[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"taste-disorders\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:taste-disorders":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,45,82,108],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100232534","hypoglossal-acupuncture-for-dysgeusia-in-patients-undergoing-chemotherapy-100232534",false,"NCT02304913","Hypoglossal Acupuncture for Dysgeusia in Patients Undergoing Chemotherapy","Hypoglossal Acupuncture for Dysgeusia in Gynecologic Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial","OralAcu","Inclusion Criteria:\n\n* Initial treatment with platinum-containing or taxane-based CTX (regardless of the the length of the CTX cycle)\n* Senological, gynecological or internistic tumors\n* Phantogeusia (on average ≥4 NRS)\n* Willingness to participate in the study and written informed consent\n\nExclusion Criteria:\n\n* Severe stomatitis\n* Dysgeusia before the CTX based on neurological diseases, diabetes, or the ingestion of drugs with taste disorders as side effects\n* Leucopenia\u002Fneutropenia\n* Intake of anticoagulants\n* Smoking\n* Severe physical or mental comorbidity (due to which the patient is unable to participate in the study)\n* Participation in other CAM treatments within the integrative oncology care\n* Participation in other studies on the effectiveness of interventions for oral complications","ALL","18 Years",{"count":20,"type":21},75,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized controlled trial aims to investigate hypoglossal acupuncture in comparison to sham acupuncture and standard medical treatment (dietary recommendations) in the treatment of dysgeusia in cancer patients undergoing chemotherapy.",[27,28,29,30,31],"Acupuncture","Taste Disorders","Dysgeusia","Chemotherapy","Cancer","RECRUITING","2026-04-09",{"date":35,"type":36},"2026-04-14","ACTUAL",{"date":38,"type":36},"2015-01-01",{"date":40,"type":21},"2027-12-31",{"name":42,"class":43},"Universität Duisburg-Essen","OTHER",3,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":56,"conditions":57,"keywords":64,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":4},"100617371","incidence-of-dysgeusia-in-breast-cancer-patients-undergoing-chemotherapy-100617371","NCT07317752","Incidence of Dysgeusia in Breast Cancer Patients Undergoing Chemotherapy","Incidenza Della Disgeusia Nei Pazienti Affetti da Carcinoma Mammario in Trattamento Chemioterapico: Uno Studio Pilota Prospettico","GustiAmo","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Diagnosis of non-metastatic breast cancer\n* Indication for neoadjuvant or adjuvant chemotherapy as part of standard clinical practice\n* Chemotherapy-naïve patients (no chemotherapy received in the previous 12 months)\n* Signed written informed consent\n\nExclusion Criteria:\n\n* Terminal or metastatic disease\n* Pre-existing taste or smell disorders (e.g., anosmia, dysgeusia, neurological syndromes, etc.)\n* Known allergies to any substances used in taste and chemesthetic function tests (e.g., quinine dihydrochloride, monosodium L-glutamate, capsaicin, etc.)\n* Receiving neoadjuvant or adjuvant chemotherapy within research protocols\n* Lack of signed written informed consent",{"count":54,"type":21},40,"OBSERVATIONAL","The goal of this observational study is to examine how frequently changes in taste occur in people with early-stage breast cancer who receive chemotherapy. It will also look at how these taste changes affect nutrition and quality of life. The main questions this study aims to answer are:\n\n* How many participants develop changes in taste during chemotherapy?\n* How do these changes affect eating habits, nutrition, and daily life?\n\nParticipants are women with non-metastatic breast cancer who are receiving chemotherapy before or after surgery.\n\nResearchers will use standardized taste tests to measure how well participants can perceive different flavors. These tests are designed to provide accurate and reproducible results.\n\nParticipants will:\n\n* Take part in taste tests during their chemotherapy treatment\n* Have their nutritional status evaluated\n* Answer questions about their quality of life",[28,58,59,60,29,61,62,63],"Breast Cancer","Quality of Life","Taste Perception","Chemotherapy Effects","Nutritional Status","Sensory Testing",[29,65,66,67,68,69,70,71],"Taste disorders","Breast cancer","Quality of life","Taste perception","Chemotherapy effects","Nutritional status","Sensory testing","NOT_YET_RECRUITING","2025-12-24",{"date":75,"type":36},"2026-01-05",{"date":77,"type":21},"2026-01",{"date":79,"type":21},"2027-12",{"name":81,"class":43},"Azienda Sanitaria Locale CN2 Alba-Bra",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":90,"targetDuration":92,"studyType":55,"phases":4,"briefSummary":93,"conditions":94,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":107},"100551124","prospective-registery-of-smelltaste-clinic-earnosethroat-100551124","NCT06456008","Prospective Registery of Smell\u002FTaste Clinic Ear\u002FNose\u002FThroat","Prospective Registry of Outcome and Correlates of Chemosensory Dysfunction at the Smell & Taste Clinic of UZ Leuven","ProspeRo'Scent","Inclusion criteria:\n\n* The psychophysical testing as well as the questionnaires require a cooperative participant who can understand and follow instructions and communicate their choices.\n* Informed consent is necessary upon participation for prospective registry.\n\nThere are no exclusion criteria related to sex, gender, or ethnicity. There are no exclusion criteria related to medical history or prior treatments.",{"count":91,"type":21},500,"5 Years","Smell\u002Ftaste disorders are common conditions with a significant impact on quality of life. In September 2021, a specific consultation for patients with smell and taste disorders was initiated at the ENT-HNS (ear, nose, and throat, head and neck surgery) department of UZ Leuven, partly in light of post-COVID-19 related smell disorders.\n\nWith this observational ambidirectional study, the investigators aim to better map smell\u002Ftaste disorders in the Belgian\u002FFlemish population. Using standard-of-care diagnostic tests and structured questionnaires, the investigators strive to gain more insight into the severity, impact, and progression\u002Fprognosis of smell\u002Ftaste disorders.",[95,28,96,97],"Olfactory Disorder","Smell Dysfunction","Smell Disorder","2025-12-09",{"date":100,"type":36},"2025-12-18",{"date":102,"type":36},"2022-12-06",{"date":104,"type":21},"2035-12-31",{"name":106,"class":43},"Universitaire Ziekenhuizen KU Leuven",1,{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":112,"acronym":113,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":115,"targetDuration":4,"studyType":22,"phases":117,"briefSummary":118,"conditions":119,"keywords":122,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":44},"100596033","gustabor-phase-1---ai-based-creation-of-a-nutritional-plan-to-compensate-for-chemotherapy-induced-taste-disorders-100596033","NCT07040189","Gustabor Phase 1 - AI-based Creation of a Nutritional Plan to Compensate for Chemotherapy-induced Taste Disorders","GustaborPilot","Inclusion Criteria:\n\n* Age ≥ 18\n* Suffering from one of the following tumor entities: Multiple myeloma or malignant tumor of the gastrointestinal tract\n* Mainly oral nutrition\n* Subjectively perceived tumor therapy-related taste disorder\n* At least two clinical presentations planned within 12 weeks with a minimum interval of three weeks\n* Ability to participate in nutritional intervention, including use of the online portal and implementation of recipe suggestions (e.g. resources and access to a kitchen), either independently or with third-party support (e.g. by relatives, outpatient care services).\n\nExclusion Criteria:\n\n* Pregnancy\n* Taste disorder explained by other causes (e.g. existing before therapy or COVID disease)\n* Placement in an inpatient care facility",{"count":116,"type":21},51,[24],"The study investigates taste disorders that commonly occur during or after cancer treatment, often leading to issues such as malnutrition and treatment discontinuation. Although many non-pharmacological recommendations exist, it is unclear which methods are suitable for which individuals. This pilot study aims to use an AI-based, or rule-driven system to generate personalized recommendations based on patients' specific impairments and taste disorder. For the pilot study, the AI will be trained on recipes to create individualized meal plans, helping to identify foods that are likely to be better. The primary endpoint is the assessment of the nutritional intervention as helpful at the second visit within 12 weeks of inclusion.",[120,121,28],"Multiple Myeloma","GI Cancer",[123,124],"taste disorders","AI","2025-06-17",{"date":127,"type":36},"2025-06-27",{"date":129,"type":21},"2025-08-01",{"date":131,"type":21},"2025-12-31",{"name":133,"class":43},"Wuerzburg University Hospital"]