[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"taste-perception\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:taste-perception":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,53],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":33,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":4},"100617371","incidence-of-dysgeusia-in-breast-cancer-patients-undergoing-chemotherapy-100617371",false,"NCT07317752","Incidence of Dysgeusia in Breast Cancer Patients Undergoing Chemotherapy","Incidenza Della Disgeusia Nei Pazienti Affetti da Carcinoma Mammario in Trattamento Chemioterapico: Uno Studio Pilota Prospettico","GustiAmo","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Diagnosis of non-metastatic breast cancer\n* Indication for neoadjuvant or adjuvant chemotherapy as part of standard clinical practice\n* Chemotherapy-naïve patients (no chemotherapy received in the previous 12 months)\n* Signed written informed consent\n\nExclusion Criteria:\n\n* Terminal or metastatic disease\n* Pre-existing taste or smell disorders (e.g., anosmia, dysgeusia, neurological syndromes, etc.)\n* Known allergies to any substances used in taste and chemesthetic function tests (e.g., quinine dihydrochloride, monosodium L-glutamate, capsaicin, etc.)\n* Receiving neoadjuvant or adjuvant chemotherapy within research protocols\n* Lack of signed written informed consent","ALL","18 Years",{"count":20,"type":21},40,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to examine how frequently changes in taste occur in people with early-stage breast cancer who receive chemotherapy. It will also look at how these taste changes affect nutrition and quality of life. The main questions this study aims to answer are:\n\n* How many participants develop changes in taste during chemotherapy?\n* How do these changes affect eating habits, nutrition, and daily life?\n\nParticipants are women with non-metastatic breast cancer who are receiving chemotherapy before or after surgery.\n\nResearchers will use standardized taste tests to measure how well participants can perceive different flavors. These tests are designed to provide accurate and reproducible results.\n\nParticipants will:\n\n* Take part in taste tests during their chemotherapy treatment\n* Have their nutritional status evaluated\n* Answer questions about their quality of life",[25,26,27,28,29,30,31,32],"Taste Disorders","Breast Cancer","Quality of Life","Taste Perception","Dysgeusia","Chemotherapy Effects","Nutritional Status","Sensory Testing",[29,34,35,36,37,38,39,40],"Taste disorders","Breast cancer","Quality of life","Taste perception","Chemotherapy effects","Nutritional status","Sensory testing","NOT_YET_RECRUITING","2025-12-24",{"date":44,"type":45},"2026-01-05","ACTUAL",{"date":47,"type":21},"2026-01",{"date":49,"type":21},"2027-12",{"name":51,"class":52},"Azienda Sanitaria Locale CN2 Alba-Bra","OTHER",{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":17,"minAge":62,"maxAge":18,"enrollmentInfo":63,"targetDuration":4,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":74,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":96},"100610097","a-sensory-strategy-to-cut-sugary-beverages-in-africanamerican-and-latine-adolescents-100610097","NCT07223151","A Sensory Strategy to Cut Sugary Beverages in African\u002FAmerican and Latine Adolescents","Trading Sugar for Sparkles in Adolescents, A Sensory Approach for Reducing Added Sugar From Sweetened Beverages","SPARKLE","Inclusion Criteria:\n\n* Adolescents ages 12 to 18 who display a \"sweet-liker\" pattern, characterized by a preference for higher concentrations of sugar in beverages, specifically identifying 0.3M (10.3% sucrose) or above as their most liked sample.\n* Have obesity (body mass index \\[BMI\\] \\> 95%). During screening, subjects' height and weight will be measured to calculate BMI, and BMI will be balanced across study arms using stratified randomization.\n* Adolescents must also indicate a willingness to drink study beverages; not currently dieting\u002Fchanging diet.\n\nExclusion Criteria:\n\n* For the primary objective. Exclusion Criteria:\n\n  * Adolescent participant is pregnant, since pregnancy affects taste perception\n  * Participant is allergic or intolerant to the items we are testing.\n\nFor the secondary objective. Exclusion Criteria:\n\n* Adolescent with type 1 or type 2 diabetes (self-declared or detected at screening visit through fasting glucose)\n* Currently consume unsweetened, sparkling water two or more times per week.\n* Adolescent participant is pregnant, since pregnancy affects taste perception\n* Participant is allergic or intolerant to the items we are testing.\n* Allergic or intolerant to the items that we are testing.",true,"12 Years",{"count":64,"type":21},63,"INTERVENTIONAL",[67],"NA","The goal of this clinical trial is to test whether replacing sugary sodas with unsweetened, flavored sparkling waters can reduce added sugar intake and improve health in Black\u002FAfrican American and Latine adolescents with obesity who prefer sweet-tasting beverages. The main questions it aims to answer are:\n\n* Does replacing sugary sodas with water change liking for sugary drinks, and water?\n* Do shifts in liking for sweetness lead to improved diet quality and cardiometabolic health?\n\nResearchers will compare replacing sugary sodas with one of three alternative beverages: unsweetened sparkling water, plain water, and beverages with gradually reduced sugar to determine which strategy is most effective.\n\nParticipants will:\n\n* Replace sugary sodas with study drinks for 4 weeks\n* Complete taste tests to measure their liking for and sensory experience of sweetness over 8-weeks\n* Provide dietary recalls, body measurements, and blood samples over 8-weeks",[70,71,28,72,73],"Obesity, Adolescent","Dietary Sugars","Insulin Resistance","Feeding Behavior",[75,76,77,28,72,78,79,80,81,82,83,84,85],"Obesity","Adolescent","Sugar-Sweetened Beverages","Sweet Taste Preference","Latine Youth","African American Youth","Dietary Intervention","Beverage Replacement","Sugar Reduction","Sensory Evaluation","Randomized Controlled Trial","RECRUITING","2025-10-29",{"date":89,"type":45},"2025-10-31",{"date":91,"type":45},"2025-07-25",{"date":93,"type":21},"2027-06",{"name":95,"class":52},"Nana Gletsu Miller",3]