[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tcm-constitution-theory\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tcm-constitution-theory":23},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":4,"overallStatus":24,"whyStopped":4,"lastUpdateSubmitDate":25,"lastUpdatePostDateStruct":26,"startDateStruct":29,"completionDateStruct":31,"leadSponsor":33,"locationsCount":4},"100616650","research-on-an-intelligent-health-recommendation-system-for-chronic-disease-comorbidity-integrating-tcm-100616650",false,"NCT07308366","Research on an Intelligent Health Recommendation System for Chronic Disease Comorbidity Integrating TCM","Research on an Intelligent Health Preservation Recommendation System for Chronic Disease Comorbidity Based on the Integration of Traditional Chinese Medicine Constitution Database and Multimodal Large Language Models","Inclusion Criteria:\n\nAge ≥ 18 years; Clear diagnosis of hypertension, type 2 diabetes, and hyperlipidemia, and a comorbid condition involving all three diseases; Stable disease condition with no recent acute complications; Capable of completing questionnaires, and willing to provide informed consent to voluntarily participate in the study.\n\nExclusion Criteria:\n\nPatients in the acute phase of the three high diseases (hypertension, diabetes, hyperlipidemia) or with severe complications (such as acute myocardial infarction or stroke); Patients with other major diseases that may affect constitution assessment or intervention implementation, such as malignant tumors, severe liver or kidney dysfunction, active tuberculosis, or mental illness; Patients who have received systematic Traditional Chinese Medicine treatment (e.g., herbal decoctions or acupuncture) within the past month, which may influence the initial assessment of constitution type; Pregnant or lactating women; Individuals unable to cooperate with measurements, with language communication barriers, or cognitive impairments; Patients participating in other interventional clinical studies.","ALL",{"count":18,"type":19},195,"ESTIMATED","OBSERVATIONAL","1. Construct a Traditional Chinese Medicine (TCM) constitution database, clarify the distribution patterns of TCM constitution in populations with comorbid \"three-high\" conditions (hypertension, hyperlipidemia, and hyperglycemia) and their associations with metabolic indicators. Establish a \"constitution-comorbidity-metabolism\" relationship model to provide a basis for personalized intervention and the development of an AI platform.\n2. Develop the AI-HEALS system by integrating the TCM constitution database with multimodal large language models. This system will generate personalized intervention plans and provide intelligent interactive Q\\&A capabilities to enhance patient intervention adherence.\n3. Evaluate the clinical application effectiveness of the AI-HEALS system, explore the relationship between changes in constitution and intervention outcomes, and validate the TCM intervention pathway of \"regulating constitution to promote health.\" This will provide both theoretical and practical guidance for the dynamic regulation and precise intervention of TCM constitution.",[23],"TCM Constitution Theory","NOT_YET_RECRUITING","2025-12-15",{"date":27,"type":28},"2025-12-29","ACTUAL",{"date":30,"type":19},"2025-12-20",{"date":32,"type":19},"2028-12-30",{"name":34,"class":35},"The Fourth Affiliated Hospital of Zhejiang University School of Medicine","OTHER"]