[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"temperature-regulation-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:temperature-regulation-disorder":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":4,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100595694","effect-of-sevoflurane-on-sweat-threshold-in-children-of-different-ages-100595694",false,"NCT07035782","Effect of Sevoflurane on Sweat Threshold in Children of Different Ages","Inclusion Criteria:\n\n1. Age: 0-12 years old;\n2. American Society of Anesthesiologists physical status I or II;\n3. Weight within the normal range and body-mass index (BMI) for age between the 25th and 85th percentiles;\n4. scheduled elective lower-body surgery under general anesthesia, expected to last at least 1 hour.\n\nExclusion Criteria:\n\n1. The guardian of the child refused to participate in the study;\n2. Operations involving extensive incisions, such as massive debridement or other operations requiring removal of large amounts of tissue;\n3. Contraindications to esophageal temperature probe insertion (e.g., esophageal varices, congenital anomalies);\n4. Thyroid dysfunction or autonomic dysfunction;\n5. Premature infants (≤1 year old).",true,"ALL","12 Years",{"count":19,"type":20},100,"ESTIMATED","INTERVENTIONAL",[23],"NA","Hypothermia is a common complication in pediatric anesthesia. Hypothermia will prolong the recovery time of anesthesia, and may also lead to increased oxygen consumption, prolonged blood coagulation time, and affect the metabolism of anesthetic drugs and postoperative immune function. Sevoflurane is the most commonly used inhaled anesthetic in children. This study explored the effect of sevoflurane on the sweat threshold of pediatric patients and analyzed the characteristics of body temperature regulation in children of different ages under anesthesia, which will help to understand the mechanism of body temperature regulation in children under anesthesia, and also provide a scientific basis for clinical anesthesia temperature management.",[26,27,28,29],"Child, Only","Temperature Regulation; Disorder","Low Body Temperatures","Sevoflurane",[31,28,29],"Pediatric Anesthesia","NOT_YET_RECRUITING","2025-06-16",{"date":35,"type":36},"2025-06-25","ACTUAL",{"date":38,"type":20},"2025-06",{"date":40,"type":20},"2026-06",{"name":42,"class":43},"Second Affiliated Hospital of Wenzhou Medical University","OTHER","Temperature Regulation Disorder"]