[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"temporomandibular-disorder-tmd\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:temporomandibular-disorder-tmd":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,53,85,117,143,185,214,242,264,300],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":34,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100636071","temporomandibular-disorder-tmd-diagnostic-concordance-between-physiotherapist-and-surgeon-100636071",false,"NCT07560917","Temporomandibular Disorder (TMD) Diagnostic Concordance Between Physiotherapist and Surgeon","Improving Access and Care Quality for Temporomandibular Disorder Patients - a Prospective Study to Examine Diagnostic Concordance Between Advanced-practice Physical Therapist and Oral and Maxillofacial Surgeon","TMD","Inclusion Criteria:\n\n* Referred for new consultation at the MUHC TMJ clinic for temporomandibular joint (TMJ) pain or dysfunction\n* Residents of the province of Quebec and benefiaries of provincial universal health insurance coverage (Régie de l'Assurance Maladie du Québec - RAMQ)\n* Be able to understand and communicate in either French of English\n* Be legally capable of providing informed consent\n\nExclusion Criteria:\n\n* Presenting for a follow-up visit (i.e., not a new consultation)\n* Have undergone TMJ surgery within the past six months\n* Referred directly from a recognized orofacial pain dentist or oral medicine specialist\n* Referred for acute TMJ trauma requiring urgent management (e.g., fractures, dislocations)\n* Present with complex or multi-system pathology that could confound the diagnostic process and are not related to TMD","ALL","18 Years","85 Years",{"count":21,"type":22},70,"ESTIMATED","INTERVENTIONAL",[25],"NA","Jaw disorders is the leading cause in facial pain, affecting many people in the world. Despite many patients finding relief from conservative treatment, many get referred to the surgeon for an evaluation. In order to improve access to care and reduce wait times, a new advanced practice physiotherapist-led triage model is being studied.",[28,29,30,31,32,33],"Temporo-mandibular Dysfunction","Temporomandibular Disorder (TMD)","Temporomandibular Dysfunction (TMD)","Temporomandibular Disorders (TMDs)","Temporomandibular Joint and Muscle Disorder","Temporomandibular Joint",[15,35,36,37,38,39,33],"Physiotherapy","Physical Therapy","Oral and Maxillofacial Surgery","Diagnostic","TMJ","NOT_YET_RECRUITING","2026-04-28",{"date":43,"type":44},"2026-05-01","ACTUAL",{"date":46,"type":22},"2026-09",{"date":48,"type":22},"2027-06",{"name":50,"class":51},"McGill University Health Centre\u002FResearch Institute of the McGill University Health Centre","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":17,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":4,"studyType":66,"phases":4,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":52},"100622604","psychosomatic-symptoms-in-patients-with-myofascial-pain-and-temporomandibular-joint-dysfunction-100622604","NCT07385781","Psychosomatic Symptoms in Patients With Myofascial Pain and Temporomandibular Joint Dysfunction","Psychosomatic Symptoms in Patients With Myofascial Pain and Temporomandibular Joint Dysfunction- A Case Control Study","Psychosomatic","Inclusion Criteria:\n\ndiagnosed patients with myofascial pain and TMD for at least six months based on Research Diagnostic Criteria for Temporomandibular Disorders (RDC\u002FTMD), Axis I, age between 20 and 60 years, literate and able to comprehend the questionnaire no prior psychological treatment for pain.\n\nExclusion Criteria:\n\nage \\\u003C20 or \\>60 years, low literacy (less than five years of formal education), history of major psychiatric or neurological disorders, diagnosed joint pathologies (e.g., arthritis, disc displacement with reduction), history of migraine or facial trauma, drug dependency and pregnancy or current use of psychotropic medication.",true,"20 Years","60 Years",{"count":65,"type":22},300,"OBSERVATIONAL","Temporomandibular joint disorder poses an intricate etiology. Biomechanical, neuromuscular and psychosocial factors may contribute to the disorder among which psychological and psychosocial disturbances have shown strong direct or indirect contribution to the disease especially when the pain is of muscular origin.",[69,29],"Psychosomatic Symptoms",[71,72,73,74,75],"Anxiety","Depression","myofascial facial pain","Perceived stress","Somatization","2026-03-16",{"date":78,"type":44},"2026-03-18",{"date":80,"type":22},"2026-03-01",{"date":82,"type":22},"2026-08-30",{"name":84,"class":51},"Bahria University",{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":92,"targetDuration":4,"studyType":23,"phases":94,"briefSummary":95,"conditions":96,"keywords":100,"overallStatus":108,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":111,"completionDateStruct":112,"leadSponsor":114,"locationsCount":116},"100629437","comparing-the-effectiveness-of-online-vs-face-to-face-physiotherapy-for-treating-temporomandibular-disorders-100629437","NCT07474662","Comparing the Effectiveness of Online vs. Face-to-face Physiotherapy for Treating Temporomandibular Disorders","Comparing the Effectiveness of Online vs. One-on-one vs. Group Physiotherapy for Treating Myogenic Temporomandibular Disorders: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients with myalgia\n\nExclusion Criteria:\n\n* Children, patients with systemic rheumatic diseases (RA, SLE..), previous jaw surgery or trauma",{"count":93,"type":22},90,[25],"Dentists and physiotherapists have two options for treating these conditions: splint therapy and physiotherapy. Right now, the gold standard is individual physiotherapy, which contains manual therapy and active exercises too. Since not many dentists and physiotherapists are experts in this area, patients have to wait for months or even years to get their treatment. Thanks to social media, patients can find many information about their condition while they are waiting, but it's our responsibility to provide safe and effective information. In view of this situation, our aim is to find out if online or group physiotherapy is as effective as individual physiotherapy.",[97,98,28,32,99,29,31],"Temporomandibular Disorders (TMD)","Orofacial Pain","TMD\u002FOrofacial Pain",[31,35,101,102,103,104,105,106,107],"Manual therapy","Online","Group physiotherapy","Individual physiotherapy","Video exercises","Telemedicine","Teledentistry","RECRUITING","2026-03-11",{"date":76,"type":44},{"date":80,"type":22},{"date":113,"type":22},"2026-07-31",{"name":115,"class":51},"Semmelweis University",2,{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":4,"eligibilityCriteria":123,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":124,"targetDuration":4,"studyType":23,"phases":126,"briefSummary":127,"conditions":128,"keywords":132,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":139,"leadSponsor":141,"locationsCount":4},"100628381","effectiveness-of-photobiomodulation-for-myofascial-pain-in-temporomandibular-disorders-100628381","NCT07460895","Effectiveness of Photobiomodulation for Myofascial Pain in Temporomandibular Disorders","Photobiomodulation in the Management of Myofascial Pain: A Randomized and Blinded Clinical Trial","Inclusion Criteria:\n\n* Individuals with myofascial TMD (ICD-9 729.1; ICD-10 M79.1) diagnosed according to the DC\u002FTMD criteria;\n* Participants aged 18 years or older;\n* Individuals able to communicate, read, write, and provide written informed consent in Portuguese.\n\nExclusion Criteria:\n\n* Patients with a history of autoimmune connective tissue diseases, such as rheumatoid arthritis, psoriatic arthritis, scleroderma, or systemic lupus erythematosus;\n* History of malignancy in the head and neck region within the past 2 years (except basal cell carcinoma) who have undergone head and neck radiation therapy and\u002For surgery affecting facial muscles;\n* Patients who have undergone temporomandibular joint surgery or orthognathic surgery;\n* Pregnant or breastfeeding women;\n* Patients with poorly adapted prostheses and\u002For prostheses associated with inadequate increase or decrease of the vertical dimension;\n* Patients with a history of tardive dyskinesia or oromandibular\u002Fcervical dystonia; -Patients with maximum mouth opening less than 35 mm;\n* Patients using systemic medications with a potential effect on pain at the time of screening will not be included in the study, including analgesics, anti-inflammatory drugs, muscle relaxants, corticosteroids, or other medications with analgesic and\u002For anti-inflammatory effects.\n\nIf a participant initiates the use of any such medication during the follow-up period, the participant will be excluded from the study.\n\n\\- Patients receiving oral and\u002For intravenous corticosteroid bolus therapy at doses \\> 1 mg\u002Fkg within the past 3 months, and those receiving biologic agents within 1 month or five times the drug half-life, whichever is longer; Individuals with mental or psychological conditions that may prevent participation in the study.",{"count":125,"type":22},140,[25],"This randomized clinical trial aims to evaluate the effectiveness of photobiomodulation therapy (PBM) alone or combined with therapeutic exercises compared with placebo PBM associated with exercises in patients with myofascial temporomandibular disorders (TMD). Participants will be allocated into three groups: PBM alone, PBM combined with exercises, or placebo PBM combined with exercises. The intervention consists of 12 treatment sessions. Outcomes related to pain intensity, mandibular function, and clinical measures will be assessed over time. The study seeks to investigate whether PBM provides additional benefits in pain reduction and functional improvement in individuals with myofascial TMD.",[129,29,130,131],"Photobiomodulation","Myofacial Pain","Pain Management",[129,133,134,131],"Myofascial Pain","Temporomandibular Disorder","2026-03-05",{"date":137,"type":44},"2026-03-10",{"date":137,"type":22},{"date":140,"type":22},"2030-12",{"name":142,"class":51},"Federal University of Rio Grande do Sul",{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":148,"acronym":149,"eligibilityCriteria":150,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":151,"targetDuration":4,"studyType":23,"phases":153,"briefSummary":154,"conditions":155,"keywords":156,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":177,"lastUpdatePostDateStruct":178,"startDateStruct":180,"completionDateStruct":182,"leadSponsor":183,"locationsCount":52},"100626567","marine-lipids-ease-painful-tmd-100626567","NCT07437313","Marine Lipids Ease Painful TMD","Safety And Analgesic Efficacy of Marine Lipid Precursors of Specialized Pro-Resolving Mediators in Adults With Chronic Temporomandibular Pain","ADAPT","Inclusion\n\nPre-screening (before Visit 0):\n\n* Age ≥18 years.\n* Pain in jaws, temples, ears, or in front of ears at least 5 days in the past 30 days, occurring monthly over the last 3 months.\n* Pain not due to toothache or ear infection.\n* Pain intensity ≥30 on a 0-100 numeric rating scale (NRS) during the week before pre-screening.\n* Willing to provide written informed consent and follow all study procedures.\n* Able to be contacted reliably during the study period.\n\nVisit 0 - Screening\u002FBaseline:\n\n* Meets all pre-screening criteria above.\n* Examiner-confirmed TMD diagnosis (myalgia or arthralgia) per DC-TMD criteria.\n* Discontinues omega-3 supplements prior to randomization and agrees not to use them during the study.\n* Will not initiate new occlusal splint therapy during the study. Participants already using a splint ≥30 days prior may continue.\n* Maintains stable facial pain management regimen:\n* No changes to regularly scheduled daily pain medications.\n* No initiation of new facial pain treatments (pharmacologic, injectable, or non-pharmacologic).\n* Episodic prescription pain medications discontinued prior to randomization, except NSAIDs, acetaminophen, or low-dose aspirin.\n\nVisit 1 - Randomization:\n\n* Completes ≥4 of 7 daily symptom diary (DSD) entries before Visit 1.\n* Average weekly pain ≥30 on 0-100 NRS, or ≥30 on at least 4 days that week.\n\nExclusion (Assessed at pre-screening and\u002For Visit 0):\n\n* Allergy or hypersensitivity to fish or seafood.\n* Botulinum toxin injections for facial pain within past 3 months.\n* Facial trauma or orofacial surgery within past 6 weeks.\n* History of renal failure or dialysis.\n* History of hyperthyroidism.\n* Immunocompromised state or autoimmune disorder.\n* History of seizure disorder or uncontrolled seizures.\n* Use of opioid medications in the past 30 days.\n* Pregnancy.",{"count":152,"type":22},100,[25],"The ADAPT study is a single-site, Phase 2b, randomized, quadruple-masked, placebo-controlled trial evaluating an omega-3 dietary supplement enriched with specialized pro-resolving mediator (SPM) precursors in adults with chronic temporomandibular disorder (TMD) pain. The trial will enroll 100 adults aged 18 years or older with examiner-confirmed TMD myalgia or arthralgia will be enrolled at the University of North Carolina at Chapel Hill, Adams School of Dentistry.\n\nParticipants are randomized 1:1 to receive either the SPM precursor supplement or a matched placebo daily for 8 weeks. Randomization is stratified by sex, and study agents are identical in appearance to maintain masking.\n\nThe study aims to evaluate whether the SPM precursor supplement:\n\nReduces facial pain intensity compared with placebo.\n\nChanges pressure pain sensitivity at the jaw and other standard body sites.\n\nAffects other aspects of chronic pain, including duration, interference with daily activities, headache burden, anxiety, depression, jaw-related quality of life, and overall patient-reported change.\n\nParticipants will record their daily facial pain intensity in electronic diaries, complete short questionnaires at baseline, Week 4, and Week 8, and undergo experimental pain testing with a handheld algometer at baseline, Week 4, and Week 8. Safety is monitored through the documentation of all adverse events throughout the study period.",[29],[157,158,159,160,161,162,163,164,165,166,167,168,169,170,171,172,173,174,175,176],"Chronic facial pain","Temporomandibular joint pain","TMD myalgia","TMD arthralgia","Orofacial pain","Specialized pro-resolving mediators (SPMs)","Omega-3 fatty acids","Marine lipid supplement","Dietary supplement intervention","Pressure pain sensitivity","Experimental pain testing","Central sensitization","Chronic pain mechanisms","Randomized controlled trial","Pain interference","Headache impact","Anxiety and depression in chronic pain","Quality of life","Migraine","Body pain distribution","2026-02-20",{"date":179,"type":44},"2026-02-27",{"date":181,"type":22},"2026-08",{"date":140,"type":22},{"name":184,"class":51},"University of North Carolina, Chapel Hill",{"id":186,"slug":187,"hasResults":11,"nctId":188,"briefTitle":189,"officialTitle":190,"acronym":39,"eligibilityCriteria":191,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":192,"targetDuration":194,"studyType":66,"phases":4,"briefSummary":195,"conditions":196,"keywords":201,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":177,"lastUpdatePostDateStruct":207,"startDateStruct":209,"completionDateStruct":211,"leadSponsor":212,"locationsCount":4},"100625961","morphometric-and-morphological-analysis-of-cervical-vertebrae-in-disc-displacement-100625961","NCT07429435","Morphometric and Morphological Analysis of Cervical Vertebrae in Disc Displacement","Imaging-Based Morphometric and Morphological Analysis of Cervical Vertebrae in Patients With TMJ Disc Displacement","Inclusion Criteria:\n\n* Presence of TMJ symptoms on at least one side, including pain, abnormal mandibular movements, or joint noises.\n* Parafunctional habits such as bruxism or clenching.\n* Patients with disc displacement of TMJ.\n\nExclusion Criteria:\n\n* Presence of malformations affecting the craniofacial region.\n* History of trauma of the maxillofacial region.\n* History of cervical surgery or any procedure involving the cervical region.\n* Patients with tumors, cysts, hypoplasia, or hyperplasia in the TMJ region.\n* Any condition related to a congenital anomaly or syndrome.\n* Presence of contraindications to magnetic resonance imaging.\n* Pregnancy.\n* Women in the breastfeeding period.",{"count":193,"type":22},115,"1 Week","Temporomandibular disorders (TMDs) are multifactorial clinical conditions affecting the masticatory muscles, the temporomandibular joint (TMJ), and the surrounding structures. The most common subtype is disc displacement, which is characterized by an abnormal position of the articular disc. Magnetic resonance imaging (MRI) is considered the gold standard for the diagnosis of disc displacement because it provides excellent soft tissue contrast, allows direct visualization of the disc, and enables dynamic evaluation. The parallel nature of mandibular and head-neck movements reflects the functional relationship between the temporomandibular and cervical neuromuscular systems. In addition, various craniofacial skeletal anomalies have been reported to be associated with disorders of the cervical vertebrae. TMD restricts mandibular movements and causes pain in the surrounding muscles, which may lead to referred pain in the neck, shoulder, and cervical muscles, thereby affecting head posture. Head and neck postural abnormalities are closely associated with cervical pain and dysfunction related to TMD. This relationship is thought to be bidirectional and can be explained through biomechanical, neurological, and pathophysiological mechanisms. In particular, upper cervical vertebral dysfunctions and changes in head position may influence the severity of TMD symptoms. For this purpose, lateral cephalometric radiography is frequently used to evaluate the hyoid position and the cervical spine in relation to the TMJ. Upper cervical vertebral anomalies and craniofacial morphological characteristics can be analyzed using these images.",[29,197,198,199,200],"Cervical Vertebrae","Disc Displacement","Dentistry","Cephalometric Analysis",[202,203,204,205,206],"temporomandibular disorder","cervical vertebrae","disc displacement","dentistry","cephalometric analysis",{"date":208,"type":44},"2026-02-24",{"date":210,"type":22},"2026-02-28",{"date":113,"type":22},{"name":213,"class":51},"Kutahya Health Sciences University",{"id":215,"slug":216,"hasResults":11,"nctId":217,"briefTitle":218,"officialTitle":219,"acronym":15,"eligibilityCriteria":220,"healthyVolunteers":61,"sex":17,"minAge":221,"maxAge":222,"enrollmentInfo":223,"targetDuration":4,"studyType":23,"phases":225,"briefSummary":227,"conditions":228,"keywords":229,"overallStatus":108,"whyStopped":4,"lastUpdateSubmitDate":233,"lastUpdatePostDateStruct":234,"startDateStruct":236,"completionDateStruct":238,"leadSponsor":240,"locationsCount":52},"100566808","early-phase-1-jit-effect-of-pain-on-dt-in-tmd-100566808","NCT06659991","JIT: Effect of Pain on DT in TMD","JIT: Effects of Pain on Laboratory Drinking Topography and Daily Drinking in People With Chronic Temporomandibular Disorder (TMD) Pain","Inclusion Criteria:\n\n* Participants in this study must be 21 years to 65 years of age and provide a driver's license or other state-issued ID.\n* Participants must also be sufficiently fluent in English to provide informed consent and understand questionnaires and instructions for laboratory procedures.\n* Participants must report drinking of, on average, at least 1 drink 3 days\u002Fweek over the past 6 months.\n* Meet Diagnostic Criteria for Temporomandibular Disorders (DC\u002FTMD) for myalgia (masticatory muscle pain), arthralgia (TMJ pain), or a combination (Schiffman et al., 2014) (TMD group only).\n* Own a smartphone with internet access.\n* Use of prescription medications will be allowed, provided they do not contraindicate alcohol use.\n\nExclusion Criteria:\n\n* Use of opioid analgesics within the past month;\n* Current major depression;\n* History of any psychotic disorder;\n* Under-controlled hypertension or diabetes (as reflected by self-report); neurological disease (e.g., multiple sclerosis, epilepsy, amyotrophic lateral sclerosis, Parkinson's disease);\n* Serious medical illness (e.g., hepatitis, HIV\u002FAIDS);\n* Impaired cognitive function;\n* History of substance use disorder (including nicotine\u002Ftobacco);\n* Alcohol naïve\n* Alcohol use disorder, or currently attempting to quit or cut down on using alcohol\n* Positive pregnancy test\n* Breastfeeding or intending to become pregnant\n* Loss of sensation in the lower leg\n* Inability to complete study tasks due to weakness, immobilization, or loss of limbs\n* Chronic pain (Control group only)\n* A urine-based drug screen for tetrahydrocannabinol, cocaine, benzodiazepines, morphine, and methamphetamine (Innovacon, Inc., San Diego, CA) will be performed. Participants testing positive for any substance will be discontinued.\n* Medications that contraindicate alcohol use","21 Years","65 Years",{"count":224,"type":22},160,[226],"EARLY_PHASE1","Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in many individuals. However, few systematic examinations of modifiable and non-modifiable risk factors, including orofacial pain status, have been conducted. This project addresses this gap in knowledge by determining the effect of pain on drinking topography in heavy drinkers with and without chronic TMD pain in both the laboratory and daily life.",[29],[230,231,232],"alcohol","temporomandibular disorder (TMD)","chronic pain","2026-02-10",{"date":235,"type":44},"2026-02-12",{"date":237,"type":44},"2025-05-14",{"date":239,"type":22},"2029-09-07",{"name":241,"class":51},"University of Minnesota",{"id":243,"slug":244,"hasResults":11,"nctId":245,"briefTitle":246,"officialTitle":247,"acronym":4,"eligibilityCriteria":248,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":63,"enrollmentInfo":249,"targetDuration":4,"studyType":66,"phases":4,"briefSummary":251,"conditions":252,"keywords":253,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":262,"locationsCount":52},"100621478","turkish-version-of-helkimo-clinical-dysfunction-index-100621478","NCT07371143","Turkish Version of Helkimo Clinical Dysfunction Index","Turkish Adaptation, Validity, and Reliability of the Helkimo Clinical Dysfunction Index","Inclusion Criteria:\n\n* Being between 18 and 60 years of age and having been diagnosed with TMB,\n* The person must be a volunteer to participate in the study,\n* The native language must be Turkish.\n\nExclusion Criteria:\n\n* Having a history of malignant conditions, trauma, or surgery in the cranial and cervical region,\n* Inability to cooperate,\n* Regular use of analgesic and anti-inflammatory drugs,\n* Having dentofacial anomalies,\n* Having active inflammatory arthritis,\n* Having metabolic diseases (gout, osteoporosis, Cushing's disease, and hyper\u002Fhypoparathyroidism),\n* Having connective tissue, rheumatological (systemic lupus erythematosus and scleroderma), and hematological disorders (anemia and leukemia),\n* Having a diagnosed psychiatric illness,\n* Having received physical therapy related to TMB less than 6 months ago,\n* Not being a native language of Turkish",{"count":250,"type":22},48,"This study aimed to translate the Helkimo Clinical Dysfunction Index (HCDI) into Turkish and to test its validity and reliability as an outcome measurement method in individuals with temporomandibular dysfunction (TMD). The study included 40 patients. Participants' pain intensity and range of jaw movement were measured, followed by the administration of the HDCI, the Fonseca Anamnestic Index (FAI), and the Mandibular Function Impairment Questionnaire (MFIQ). For test-retest reliability, the same questionnaire was administered again to the same patients two weeks later, and the FAI was used to test the validity of the questionnaire.",[29],[202,254,255],"helkimo clinical dysfunction Index","Turkish Adaptation, Reliability, and Validity","2026-01-18",{"date":258,"type":44},"2026-01-27",{"date":260,"type":22},"2026-01-25",{"date":137,"type":22},{"name":263,"class":51},"Sevgi Medical Center",{"id":265,"slug":266,"hasResults":11,"nctId":267,"briefTitle":268,"officialTitle":269,"acronym":4,"eligibilityCriteria":270,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":222,"enrollmentInfo":271,"targetDuration":4,"studyType":23,"phases":273,"briefSummary":274,"conditions":275,"keywords":277,"overallStatus":108,"whyStopped":4,"lastUpdateSubmitDate":291,"lastUpdatePostDateStruct":292,"startDateStruct":294,"completionDateStruct":296,"leadSponsor":298,"locationsCount":52},"100587747","orofacial-pain-self-management-personality-moderation-effect-100587747","NCT06932406","Orofacial Pain Self-management: Personality Moderation Effect","Orofacial Pain Self-management: Personality Moderation Effect - Randomized Clinical Trial","Inclusion Criteria:\n\n* The patient presents TMDs diagnosed according to the CD\u002FTMD classification.\n* Age between 18 and 65.\n* Presence of pain in mandibular, temporal, facial, peri-auricular and\u002For auricular regions.\n* Presence of chronic orofacial pain. Defined by the ICD-11 as orofacial pain or headache that occurs for more than two hours a day for 50% of the days of the last three months.\n* Orofacial pain is related to TMDs according to the International Classification of Headaches.\n* Moderate pain intensity, corresponding to a weekly average of at least 30 mm on a 100 mm VAS (validated representation of moderate pain on the VAS scale = 31-54 mm)\n\nExclusion Criteria:\n\n* Concomitant rheumatic systemic pathologies.\n* History of trauma or recent surgical intervention in the head, face, neck or chest.\n* Presence of intraoral infections or odontogenic pain.\n* Headache of neuropathic origin (trigeminal neuralgia, Arnold neuralgia, etc.).\n* Being receiving therapy (except rescue pharmacological therapy) for this disorder or pain.\n* Cognitive impairment that prevents the follow-up of an educational program (determined through the MoCA questionnaire)",{"count":272,"type":22},98,[25],"The objective of this clinical trial is to study the effect of self-management on pain perception in patients with chronic orofacial pain and temporomandibular disorders (TMD) comparing it with the conventional treatment proposed by the TMD clinical practice guidelines. It also evaluates its effect on function and various psychosocial variables.\n\nAs a secondary objective, this work proposes to study the variability between patients, in terms of personality factors, as moderators of the effect of treatment on pain perception. Including in the proposed statistical models certain covariates such as perception and\u002For coping with stress, anxiety and other psychosocial variables.\n\nThis is a randomized clinical trial with two intervention groups and three measurement times (T0; pre-intervention, T1; post-5 weeks and T2; post-6 months). The experimental group will be applied a protocol based on self-management, which includes: therapeutic education, cognitive-behavioral tools, therapeutic exercise of the temporomandibular region, mind-body strategies and modifications of aspects related to lifestyle. The control group will carry out an intervention program based on the Clinical Practice Guidelines for the Management of Temporomandibular Joint Disorders. Therefore, using a set of tools based on therapeutic education, cognitive-behavioral tools for bruxism and other parafunctional habits, temporomandibular region exercises and manual therapy.",[276,29,97,30],"Chronic Orofacial Pain",[278,161,279,280,281,282,283,284,285,286,287,288,289,290],"Temporomandibular disorder","Self-management","self-efficacy","therapeutic exercise","therapeutic education","cognitive behavioral","mind-body techniques","Lifestyle modification training","manual therapy","personality","psychosocial","biopsychosocial","physiotherapy","2025-12-01",{"date":293,"type":44},"2025-12-08",{"date":295,"type":44},"2025-11-28",{"date":297,"type":22},"2026-05-24",{"name":299,"class":51},"Fundación Universidad Católica de Valencia San Vicente Mártir",{"id":301,"slug":302,"hasResults":11,"nctId":303,"briefTitle":304,"officialTitle":305,"acronym":306,"eligibilityCriteria":307,"healthyVolunteers":61,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":308,"targetDuration":4,"studyType":66,"phases":4,"briefSummary":310,"conditions":311,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":313,"lastUpdatePostDateStruct":314,"startDateStruct":316,"completionDateStruct":317,"leadSponsor":319,"locationsCount":4},"100605513","occlusal-sensitivity-to-articulating-foils-in-patients-with-temporomandibular-disorders-and-healthy-controls-100605513","NCT07163494","Occlusal Sensitivity to Articulating Foils in Patients With Temporomandibular Disorders and Healthy Controls","Assessment of Occlusal Sensitivity to Articulating Foils in Patients With Temporomandibular Disorders Compared to Healthy Controls: A Case-Control Study","SENFOIL","Inclusion Criteria:\n\nReported pain in the temporomandibular joint (TMJ) and\u002For masticatory muscles persists for more than 3 months.\n\nSpontaneous pain \\>30 mm on the Visual Analogue Scale (VAS) at the time of the first examination.\n\n\\-\n\nExclusion Criteria:\n\nLoss of posterior teeth leads to loss of occlusal support zones.\n\nPosterior removable dentures.\n\nPoor oral hygiene or periodontal disease.\n\nOrofacial pathology unrelated to TMD diagnosis.\n\nAcute pain (duration \\\u003C3 months).\n\nHistory of head and neck trauma.\n\nHeadache not related to TMD (according to the International Classification of Headache Disorders, ICHD-II).\n\nPain caused by fibromyalgia.\n\nSystemic diseases or diagnosed psychiatric disorders.\n\nHistory of pain medication abuse or current substance abuse.\n\n\\-",{"count":309,"type":22},80,"Occlusal sensitivity refers to the ability to detect fine objects placed between opposing teeth during biting or in maximum intercuspation. Two main approaches are commonly used to assess occlusal sensitivity and the periodontal sensory threshold: one measures the minimal detectable force using monofilaments, while the other evaluates the sensitivity threshold to interocclusal thickness with articulating foils. In healthy individuals, occlusal sensitivity ranges from 2 µm to 77 µm (average 24 µm) and tends to decrease with age. Periodontal mechanoreceptors are primarily responsible for this function, although studies indicate that other mechanoreceptors may contribute, especially in individuals with implants or prostheses. Evidence suggests that patients with painful temporomandibular disorders (TMD) may have reduced occlusal sensitivity and show less adaptability to occlusal interferences than healthy subjects. This observational case-control study assesses differences in occlusal sensitivity between patients with pain-related TMD and healthy controls. The study will also explore the relationship between sensory sensitivity, psychosomatic characteristics, and the clinical manifestations of TMD. The TMD group will include patients from the Department of Removable Prosthodontics and the Department of Oral Medicine at the University of Zagreb School of Dental Medicine, diagnosed with pain-related TMD (including myalgia, referred myofascial pain, and\u002For arthralgia) according to the DC\u002FTMD criteria. The control group will consist of healthy volunteers matched for age and sex, with no neurological alterations in sensory function. The study has been approved by the Ethics Committee of the University of Zagreb School of Dental Medicine and will be conducted in accordance with the Declaration of Helsinki. All participants will receive detailed information about the study and provide written informed consent before participation. The experimental procedure will test occlusal sensitivity by assessing the ability of participants to detect different thicknesses of articulating foils, applied in randomised order between upper and lower molars, including a sham test. Participants will report whether they detect the foil, and their responses will be recorded for subsequent statistical analysis.",[29,312],"Chronic Pain","2025-09-01",{"date":315,"type":44},"2025-09-09",{"date":313,"type":22},{"date":318,"type":22},"2025-11-01",{"name":320,"class":51},"University of Zagreb"]