[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"temporomandibular-joint-disc-displacement-without-reduction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:temporomandibular-joint-disc-displacement-without-reduction":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,71],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100638314","arthroscopic-lysis-and-lavage-with-and-without-intra-articular-injection-of-hyaluronic-acid-in-patients-with-ddwor-in-tmj-100638314",false,"NCT07614932","Arthroscopic Lysis and Lavage With and Without Intra-articular Injection of Hyaluronic Acid in Patients With DDwoR in TMJ","Assessment of Arthroscopic Lysis and Lavage With And Without Intra-Articular Injection of Hyaluronic Acid in the Management of Patients With Disc Displacement Without Reduction: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Adults above 18 years old.\n2. Diagnosis of Disc Displacement Without Reduction (DDWOR) with limited mouth : eitherunilateral or bilateral based on the DC\u002FTMD and confirmed with MRI\n3. History of unsuccessful conservative treatment such as physical therapy, occlusal splints,or medications (e.g., NSAIDs, muscle relaxants) for at least 3 months.\n4. Patients must sign the informed consent, understand the study procedures and potential risks, accept to volunteer in the study and be available to attend the follow-up visits.\n\nExclusion Criteria:\n\n1. Degenerative Temporomandibular Joint Disorders (e.g., osteoarthritis, rheumatoid arthritis).\n2. History of prior TMJ surgery (e.g., joint replacement, previous arthroscopy).\n3. Severe Systemic Conditions (e.g., cardiovascular disease, autoimmune disorders, uncontrolled diabetes).\n4. Active joint infection, acute inflammation, or presence of any condition that may increase the risk of complications from arthroscopic surgery or injections (e.g., local infection, uncontrolled bleeding disorders).\n5. Pregnancy or Breastfeeding.\n6. Patients with severe Psychological Conditions (e.g., severe depression, psychosis, myofascial pain disorder) or dental related pain will be identified at the initial assessment and referred for appropriate psychological, behavioural, or dental management prior to inclusion in the study.","ALL","18 Years",{"count":19,"type":20},52,"ESTIMATED","INTERVENTIONAL",[23],"NA","The study aims to assess the outcomes of arthroscopic lysis and lavage procedure with and without single intra-articular injection of hyaluronic acid in managing patients with anterior disc displacement without reduction.\n\nThe research question that this study will answer is:\n\nDoes arthroscopic lysis and lavage combined with hyaluronic acid provide better outcomes in terms of pain intensity and maximum mouth opening compared to arthroscopic lysis and lavage alone?",[26,27,28,29,30],"TMJ Disc Disorder","Temporomandibular Joint Disc Displacement, Without Reduction","TMD\u002FOrofacial Pain","Temporomandibular Disorder","TMJ Closed Lock",[32,33,34],"TMJ arthroscopy","TMJ arthroscopic lysis and lavage","Anterior Disc Displacement without reduction","NOT_YET_RECRUITING","2026-05-22",{"date":38,"type":39},"2026-05-29","ACTUAL",{"date":41,"type":20},"2026-05",{"date":43,"type":20},"2027-01",{"name":45,"class":46},"Cairo University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":56,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":69,"locationsCount":47},"100576197","long-term-follow-up-of-tmj-surgery-and-evaluation-of-the-6-month-control-as-a-prognostic-marker-100576197","NCT06782165","Long-term Follow up of TMJ Surgery and Evaluation of the 6-month Control as a Prognostic Marker.","Inclusion Criteria:\n\n* Patients participating in the studies with ethical approval numbers EPN 2014\u002F764-31\u002F2 and 2014\u002F622-31\u002F1.\n* Initial diagnosis DDwR or DDwoR.\n\nExclusion Criteria:\n\n* Patient unable to verify informed consent.",{"count":55,"type":20},91,"10 Years","OBSERVATIONAL","The goal of this clinical trial is to evaluate the long-term outcome of surgical intervention (arthroscopy or discectomy) due to the diagnoses temporomandibular joint disc displacement with or without displacement. The main questions it aims to answer are:\n\n* Does the surgical outcome recorded at the earlier 6-month follow up persist at the long-term follow up approximately 10 years postoperatively?\n* How does the radiologically determined degree of joint degeneration change with time in patients that have had joint surgery? Researchers will compare the six-month surgical outcome to the ten-year outcome to see if temporomandibular joint surgery results are stable over time.\n\nParticipants with an earlier performed joint surgery will:\n\n* Have a clinical examination approximately ten years postoperatively.\n* Have a temporomandibular joint x-ray scan performed (cone-beam computed tomography).",[60,61,27],"Temporomandibular Disorders (TMD)","Temporomandibular Joint Disc Displacement, With Reduction","RECRUITING","2025-12-09",{"date":65,"type":39},"2025-12-17",{"date":67,"type":39},"2025-04-01",{"date":41,"type":20},{"name":70,"class":46},"Karolinska Institutet",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":21,"phases":81,"briefSummary":82,"conditions":83,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":89,"leadSponsor":91,"locationsCount":47},"100576198","tmj-arthroscopy-compared-to-arthrocentesis-in-disc-displacement-without-reduction-100576198","NCT06782178","TMJ Arthroscopy Compared to Arthrocentesis in Disc Displacement Without Reduction","Temporomandibular Joint Arthroscopic Lysis and Lavage Compared to Arthrocentesis in Disc Displacement Without Reduction: a Randomised, Double-blind, Controlled Trial","ACALL","Inclusion Criteria:\n\n* Uni- or bilateral DDwoR affecting the patients mouth opening capacity to a range of ≤ 35 mm, verified with clinical and magnetic resonance imaging (MRI) findings.\n* TMJ pain ≥ 3 (NRS)\n* TMJ disability ≥ 3 (NRS)\n* Age ≥ 18 years\n\nExclusion Criteria:\n\n* Prior open TMJ surgery\n* Patient diagnosed with rheumatologic joint disease.\n* ASA (American Society of Anaesthesiologists) \\> 3\n* Patient unable to verify informed consent.",{"count":80,"type":20},100,[23],"The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention arthrocentesis in treating disabling and painful temporomandibular joint disc displacement without reduction. The main questions it aims to answer are:\n\n* Which surgical method that best improves mouth opening capacity, TMJ pain, and TMJ disability?\n* If any pre- or peri-operative variable\u002F-s could be identified as a predictor for surgical outcome? Researchers will compare arthroscopic lysis and lavage to arthrocentesis to see if arthroscopic lysis and lavage works better to treat temporomandibular joint disc displacement.\n\nParticipants will:\n\n* Have one of the two interventions under general anesthesia, not knowing which intervention.\n* Visit an external clinic for regular checkups at 1, 3, 6, 12, and 24 months after surgery.\n* Answer three different quality of life surveys at the checkups.",[84,27,60],"Temporomandibular Joint Disc Displacement","2025-06-27",{"date":87,"type":39},"2025-06-29",{"date":67,"type":39},{"date":90,"type":20},"2030-02",{"name":70,"class":46}]