[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tendon-adhesion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tendon-adhesion":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100571709","phase-2-surgical-release-of-hand-tendons-with-wrapping-of-the-released-tendon-using-an-amniotic-membrane-100571709",false,"NCT06723782","Surgical Release of Hand Tendons with Wrapping of the Released Tendon Using an Amniotic Membrane","Inclusion Criteria:\n\n* Man or woman aged 18 to 65 years old\n* Adhesion of a flexor and\u002For extensor tendon of the hand.\n* Adhesion localized to a single finger.\n* Adhesion that has been present for at least 3 months following primary repair, despite high-quality rehabilitation. Primary repair is defined as the repair of a tendon injury, fracture, crush injury of the finger, infection, etc., leading to the adhesion of the tendon to surrounding tissue.\n* Patient with a total passive range of motion of the proximal and distal interphalangeal joints of at least 150°.\n* Informed and consenting patient.\n* Patient enrolled in a social security plan or a beneficiary of such a plan.\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding woman, or without an effective method of contraception.\n* Patient requiring tenolysis after tendon grafting for the reconstruction of a deep common flexor or after reimplantation.\n* Patient with amputated hand(s).\n* Patient with an untreated fracture or non-union in the affected hand.\n* Patient requiring multiple surgical interventions that may be potential confounding factors, particularly those involving additional incisions.\n* Patient unable to understand rehabilitation or follow the study protocol.\n* Patient with a contraindication to anesthesia.\n* Person deprived of liberty by judicial or administrative decision.\n* Adult subject to legal protection measures or incapable of expressing consent.","ALL","18 Years","65 Years",{"count":19,"type":20},16,"ESTIMATED","INTERVENTIONAL",[23],"PHASE2","The goal of this clinical trial is to evaluate whether an amniotic membrane can function as an effective anti-adhesive barrier following surgical release of tendon adhesions. The main question the clinical trial aims to answer is:\n\n\\- Can wrapping an amniotic membrane around a surgically released tendon help reduce recurrence of adhesions and promote recovery of hand functionality?\n\nParticipants will:\n\n* Undergo surgical treatment (surgical release of the tendon adhesions and wrapping of the amniotic membrane around the release tendon) on Day 0.\n* Visit the center for a series of tests 15 days, 6 weeks, 3 months, 6 months after the surgical intervention.",[26,27],"Tendon Adhesion","Tenolysis","RECRUITING","2024-12-04",{"date":31,"type":32},"2024-12-09","ACTUAL",{"date":34,"type":32},"2024-02-15",{"date":36,"type":20},"2026-08",{"name":38,"class":39},"TBF Genie Tissulaire","INDUSTRY"]