[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tension-type-headache\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tension-type-headache":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,17,0,[8,50,82,112,149,177,201,227,258,285,311,333,354,379,401,428,451],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100492269","dance-therapy-and-chronic-pain-100492269",false,"NCT05689944","Dance-therapy and Chronic Pain","Effect of Dance-therapy on Chronic Adolescent Pain Patients - a Randomized Controlled Trial Study","ALGODANCE","Inclusion Criteria:\n\n* Patients aged 12 to 20 years, girls or boys, with chronic pain.\n* Diagnosis of chronic pain made in a Pain Management Center\n* Patients followed in a Pain Management Center (to ensure that patients entering the protocol have pain that is not relieved by conventional treatments)\n* Patients who have given written consent for adults or whose parents have given consent for minors\n* Patients who are affiliated with or benefit from a social security system.\n\nExclusion Criteria:\n\n* Patients with other neurological or psychological disorders\n* Patients with psychiatric illnesses\n* Patients with chronic infectious, metabolic, cancerous, autoimmune diseases.\n* Non-communicating patients including deaf and hard of hearing patients\n* Patients or parents who do not speak or read French\n* Pregnant women\n* Dance or yoga professionals (dance or yoga teachers or those studying to become teachers)","ALL","12 Years","20 Years",{"count":21,"type":22},160,"ESTIMATED","INTERVENTIONAL",[25],"NA","Pain, when it becomes chronic, can be a threat to patients and it is very common to observe a fear of pain and a fear of movement (kinesiophobia). Avoidance of movement due to fear of pain can lead to a deterioration of body image. Non-medicinal therapies are essential to correct this fear and movement avoidance behavior, to decrease \"catastrophic\" judgments and thus anxiety. The use of art-therapy in the accompaniment of patients with pain has shown, in particular, decreases in the intensity of pain, the level of anxiety, an improvement in stress, mood and overall psychological state. However, according to the current literature, it appears that 1) this technique is rarely used in children or adolescents, for whom non-medicinal therapies are fundamental, and 2) in the case of chronic pain, the form of art used is very rarely related to the body (most often painting, drawing, music...).\n\nIn this project, investigators propose to set up and test the potential benefit of art-therapy sessions related to the body, namely dance-therapy, in adolescents and young adults suffering from chronic pain.",[28,29,30],"Chronic Pain","Complex Regional Pain Syndromes","Tension-Type Headache",[32,33,34,35,36],"Dance-therapy","Chronic pain","Complex Regional Pain Syndrome","Tension Type Headache","Adolescents","RECRUITING","2026-06-16",{"date":40,"type":41},"2026-06-18","ACTUAL",{"date":43,"type":41},"2024-03-01",{"date":45,"type":22},"2030-10",{"name":47,"class":48},"Hospices Civils de Lyon","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":81},"100643394","fire-needling-plus-filiform-needling-for-chronic-migraine-with-comorbid-tension-type-headache-100643394","NCT07633522","Fire Needling Plus Filiform Needling for Chronic Migraine With Comorbid Tension-Type Headache","Clinical Research on Fire Needling Combined With Filiform Needling for Chronic Migraine With Comorbid Tension-type Headache","Inclusion Criteria:\n\n* Meets the diagnostic criteria for tension-type headaches with pericranial tenderness;\n* Meets the diagnostic criteria for chronic migraine;\n* 18 years ≤ age ≤ 65 years;\n* Has sufficient understanding to complete the necessary examinations and tests for the study;\n* Voluntarily joins this study and signs the informed consent form.\n\nExclusion Criteria:\n\n* Patients complicated with cluster headache or other primary headaches;\n* Patients with secondary headaches caused by intracranial space-occupying lesions, cranial infections, etc.;\n* Patients complicated with severe heart, liver or kidney impairment, coagulation disorders, infections, severe immunocompromise, or allergic predisposition;\n* Patients with alcohol or drug dependence;\n* Patients who are unable to cooperate with acupuncture treatment;\n* Women who are planning pregnancy, pregnant or breastfeeding;\n* Patients who have received acupuncture treatment within 3 months prior to enrollment.","18 Years","65 Years",{"count":60,"type":22},88,[25],"The investigators conducted a multicenter, prospective, randomized controlled clinical study to learn whether fire needling combined with filiform needling applied to pericranial muscle tenderness areas can effectively treat chronic migraine with comorbid tension-type headache. The study will also evaluate the safety and long-term efficacy of this therapy. Its main target questions include:\n\n1. Can fire needling significantly reduce the number of headache days per month?\n2. What is the effect of this therapy on headache intensity, emotional symptoms, and quality of life? The investigators will compare \"fire needling at pericranial tender points plus conventional filiform needling\" versus \"conventional filiform needling alone\" to verify whether the key technique of fire needling plus conventional filiform needling provides unique additive value.\n\nParticipants will:\n\n1. Receive treatment twice per week for 8 weeks (either in the experimental group or the control group)，attend a follow-up visit at week 24 after enrollment\n2. Keep a headache diary (recording headache frequency, pain intensity, duration, associated symptoms, etc.)\n3. Regularly complete assessments of emotional status, quality of life, and number of pericranial tender points",[64,65],"Chronic Migraine","Tension-type Headache",[67,68,69,70],"fire needling","filiform needling","chronic migranie","tension-type headache","NOT_YET_RECRUITING","2026-06-04",{"date":74,"type":41},"2026-06-08",{"date":76,"type":22},"2026-08",{"date":78,"type":22},"2028-12",{"name":80,"class":48},"Beijing Hospital of Traditional Chinese Medicine",3,{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":90,"minAge":91,"maxAge":58,"enrollmentInfo":92,"targetDuration":4,"studyType":23,"phases":94,"briefSummary":95,"conditions":96,"keywords":97,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":49},"100629654","effect-of-manuel-therapy-on-tension-type-headache-in-menopausal-and-premenopasual-women-100629654","NCT07477483","Effect of Manuel Therapy on Tension Type Headache in Menopausal and Premenopasual Women","Comparison of the Effect of Manuel Therapy on Tension Type Headache in Menopausal and Premenopasual Women","TTH-MT","Inclusion Criteria:\n\n* Female participants aged between 45 and 65 years.\n* Diagnosis of tension-type headache.\n* Premenopausal or menopausal status.\n* HIT-6 score of 49 or higher.\n* Willingness to participate in the study.\n\nExclusion Criteria:\n\n* Use of hormone therapy.\n* History of cervical surgery.\n* History of neurological disease.\n* Pregnancy.\n* Inability to understand questionnaire forms.\n* Failure to attend treatment sessions.","FEMALE","45 Years",{"count":93,"type":22},50,[25],"This study aims to investigate the effectiveness of manual therapy in women with tension-type headache and to compare treatment outcomes between menopausal and premenopausal women. Hormonal changes occurring during menopause may influence pain perception and headache characteristics.\n\nParticipants diagnosed with tension-type headache will receive manual therapy interventions. Headache intensity, headache-related disability, pressure pain threshold, cervical range of motion, sleep quality, and quality of life will be evaluated before and after treatment using validated assessment tools. The results are expected to contribute to physiotherapy approaches in women experiencing tension-type headache during different hormonal periods.",[35],[98,35,99,100,101,102],"Manuel Therapy","Women","Menopause","Premenopause","Physiotherapy","2026-05-16",{"date":105,"type":41},"2026-05-20",{"date":107,"type":41},"2025-10-01",{"date":109,"type":22},"2026-05",{"name":111,"class":48},"Necmettin Erbakan University",{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":91,"enrollmentInfo":120,"targetDuration":4,"studyType":23,"phases":122,"briefSummary":123,"conditions":124,"keywords":127,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":49},"100611434","efficacy-of-a-multimodal-physiotherapy-program-and-mobile-app-guided-meditation-in-adults-with-frequent-or-chronic-tension-type-headache-100611434","NCT07240532","Efficacy of a Multimodal Physiotherapy Program and Mobile-App Guided Meditation in Adults With Frequent or Chronic Tension-Type Headache","Efficacy of a Multimodal Physiotherapy Program and Mobile-App Guided Meditation in Adults With Frequent or Chronic Tension-Type Headache: A Randomized Clinical Trial","JBE-CEF","Inclusion Criteria:\n\n* Diagnosis of frequent or chronic tension-type headache (TTH) according to the International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria.\n* Ability to understand and communicate in Spanish sufficiently to follow instructions and complete questionnaires.\n* Willingness to provide written informed consent and comply with study procedures.\n\nExclusion Criteria:\n\n* Diagnosis of migraine or other primary or secondary headache disorders.\n* Presence of red flags for manual therapy, including bone pathology, inflammatory disease, malignancy, neurological disorders, vestibular dysfunction, or skin infection in the cervical area.\n* Fibromyalgia, pregnancy, or lactation.\n* Use of pacemakers or implantable defibrillators.\n* Recent medication adjustments, particularly involving psychotropic or chronic pain drugs.\n* Severe psychiatric disorders (major depressive episode, bipolar disorder, schizophrenia, or other psychotic conditions).\n* Previous physical treatment targeting the cranio-cervical region (manual therapy, dry needling, anesthetic blocks) within the last six months.\n* Regular practice of meditation or mindfulness during the last six months.\n* Participation in another clinical trial during the study period.",{"count":121,"type":22},78,[25],"The goal of this clinical trial is to evaluate whether a multimodal physiotherapy program and guided meditation using a mobile app can help reduce headache pain and improve quality of life in adults with frequent or chronic tension-type headache. The study analyzes the effects of physical and psychological interventions applied both separately and in combination, so that the combined treatment addresses tension-type headache as a multifactorial condition influenced by biopsychophysiological factors, integrating physical and psychological strategies to improve participants' overall well-being.\n\nThe main questions it aims to answer are:\n\n* Does multimodal physiotherapy lower the intensity and frequency of headaches?\n* Does guided meditation through a mobile app help reduce stress and improve emotional well-being?\n* Are the combined effects of physiotherapy and meditation greater than either intervention alone?\n\nThe study will compare:\n\n* A group receiving multimodal physiotherapy sessions once a week for four weeks,\n* A group practicing guided meditation with a mobile app for about 5 to 7 minutes daily,\n* A group combining both physiotherapy and meditation.\n\nParticipants will:\n\n* Attend clinical sessions or use the meditation app depending on group assignment,\n* Complete short questionnaires about pain, stress, sleep, and daily functioning,\n* Record headache episodes in a structured diary during the study period.",[30,125,126],"Chronic Tension-type Headache","Frequent Episodic Tension-Type Headache",[30,128,129,130,131,132,133,134,135,136,137,138,139],"Chronic Tension-Type Headache","Multimodal Physiotherapy","Manual Therapy","Dry Needling","Mindfulness","Guided Meditation","Mobile Application","Non-Pharmacological Treatment","Randomized Controlled Trial","Biopsychophysiological Approach;","Pain Management","Headache Disability","2026-05-05",{"date":142,"type":41},"2026-05-11",{"date":144,"type":22},"2026-07",{"date":146,"type":22},"2027-06",{"name":148,"class":48},"Universidad de Granada",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":153,"acronym":154,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":156,"targetDuration":158,"studyType":159,"phases":4,"briefSummary":160,"conditions":161,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":176},"100464994","china-headache-disorders-registry-100464994","NCT05334927","China HeadAche DIsorders RegiStry","CHAIRS","Inclusion Criteria:\n\n1. Age ≥ 12 years old,Any gender;\n2. The first onset age of primary headache was less than 50 years old(Age \\\u003C65 years at first diagnosis of chronic migraine);\n3. patients with primary headache (migraine, tension headache and other types of primary headache) or primary headache complicated with MOH according to ICHD-3;\n4. Sign the informed consent form.\n\nExclusion Criteria:\n\n1. According to the ICHD-3 diagnostic criteria, there are still headaches directly related to secondary factors (except drug overuse) at the time of enrollment;\n2. Those who cannot be diagnosed as primary headache or primary headache combined with medication overuse headache according to ICHD-3;\n3. According to DSM-V diagnostic criteria, patients with severe mental diseases (such as schizophrenia, mental disorders associated with mental retardation, etc.);\n4. Patients with severe organic diseases, such as malignant tumors, and the expected survival time is less than 1 year;\n5. Pregnant,planning pregnancy or Lactating women;\n6. Subjects participating in other clinical trials;\n7. Unable to cooperate to complete the follow-up due to geographical or other reasons",{"count":157,"type":22},10000,"1 Month","OBSERVATIONAL","It is planned to include 10000 patients. In the China HeadAche DIsorders RegiStry CHAIRS）, patients aged over 12 years with primary headache and medication-overuse headache(MOH) were collected. The biomarkers, imaging features, cognition, genetic characteristics, ocial and demographic data, medical data, therapeutics used, and outcome of headache-related diseases were studied, and long-term follow-up was planned.",[162,163,164,165,30,166],"Headache Disorders, Primary","Migraine","New Daily Persistent Headache","Medication Overuse Headache","Trigeminal Autonomic Cephalalgia","2026-01-12",{"date":169,"type":41},"2026-01-15",{"date":171,"type":41},"2022-08-29",{"date":173,"type":22},"2032-12-31",{"name":175,"class":48},"Beijing Tiantan Hospital",20,{"id":178,"slug":179,"hasResults":11,"nctId":180,"briefTitle":181,"officialTitle":182,"acronym":4,"eligibilityCriteria":183,"healthyVolunteers":11,"sex":17,"minAge":184,"maxAge":185,"enrollmentInfo":186,"targetDuration":4,"studyType":23,"phases":188,"briefSummary":189,"conditions":190,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":49},"100564595","to-stuidy-the-effect-of-cognitive-behavior-threapy-cbt-on-smartphone-addiction-patients-with-tension-type-headache-100564595","NCT06631222","to Stuidy the Effect of Cognitive Behavior Threapy CBT on Smartphone Addiction Patients With Tension Type Headache","Effect of Cognitive Behaviour Approach on Subjects With Smartphone Addiction","Inclusion Criteria:\n\n* Subjects were those diagnosed with tension type headache by neurologists based on the criteria of the International Headache Society.\n* age between 19-34.\n* International Headache Society diagnostic criteria of tension type headaches:\n* Frequent ETTH or CTTH diagnosed, in both cases more than three months.\n* Episodes of pain from 30 minutes to 7 days Fulfil 2 or more of the following characteristics:\n* Bilateral location of pain.\n* Non-pulsatile pain pressure.\n* Pain mild to moderate.\n* The headache does not increase with physical activity.\n* The headache may be associated with pericranial tenderness.\n* Controlled pharmacologically.\n* Myofascial TrPs were bilaterally explored in upper trapezius, splenius capitis, sternocleidomastoid, masseter, superior oblique, levator scapulae and suboccipital muscles, TrP diagnosis was conducted following the diagnostic criteria:\n* presence of a palpable taut band within a skeletal muscle.\n* presence of a hypersensitive tender spot in the taut band.\n* local twitch response elicited by snapping palpation of the taut band reproduction of the typical referred pain pattern of the TrP in response to compression.\n* TrPs were considered active if both the local and the referred pain evoked by manual palpation reproduced total or partial pattern of the headache.\n* Patients with FHP who have craniovertebral angle less than 49 degrees were included. Forward head posture is measured by calculating the angle between the horizontal line passing through C7 and a line extending from the tragus of the ear to C7.\n* patients with smartphone addiction who will score 31 for males and 33 for females on smartphone addiction scale - short version.\n\nExclusion Criteria:\n\n* rheumatoid arthritis.\n* suspected malignancy.\n* pregnancy.\n* if they had received manual therapy treatment in the 2 months before enrolment into the study.\n* Patients with infrequent episodic tension type headache, or with probable frequent and infrequent forms of tension type headache or other concomitant headache.\n* They can never have vomiting or headache episodes during the treatment.\n* Episodic tension type headache patients may experience very occasionally photophobia or phonophobia during their episodes of headache.\n* Chronic tension type headache patients may experience very occasionally photophobia, phonophobia or mild nausea during headache episodes.\n* Pain aggravated by movement of the head.\n* Metabolic or musculoskeletal problems with similar headache symptoms.\n* Previous trauma to the cervical spine.\n* Active vertigo history.\n* Poorly controlled hypertension.\n* Atherosclerosis.\n* Advanced osteoarthritis.\n* Patients undergoing pharmacological adaptation or changes in the prophylactic medication.\n* Excessive emotional stress.\n* Patients with heart devices.\n* Joint instability.\n* Neurological disorders.\n* Laxity of cervical soft tissues.\n* Radiographic abnormalities.\n* Generalized hyperlaxity or hypermobility.","19 Years","34 Years",{"count":187,"type":22},40,[25],"The goal of this clinical trial is to learn if cognitive behavioral approach works to treat tension type headache in smartphone addiction in adults. The main questions it aims to answer are:\n\nIs there an effect of adding cognitive behavior approach to physical therapy (manual therapy, corrective exercise therapy) on pain pressure threshold, forward head posture and headache intensity in smartphone addiction patients with tension-type headache? Researchers will compare adding cognitive behavior approach to physical therapy (manual therapy, corrective exercise therapy) to see if cognitive behavior approach works to treat tension type headache in smartphone addiction than physical therapy alone.\n\nParticipants will:\n\nAll participants will receive twelve treatment sessions (twice per week) in a 6 weeks period with a rest period of 48 to 72 hour between them.",[35,191],"Smartphone Addiction","2025-11-25",{"date":194,"type":41},"2025-11-26",{"date":196,"type":41},"2025-01-29",{"date":198,"type":22},"2026-01",{"name":200,"class":48},"Hatem Mostafa",{"id":202,"slug":203,"hasResults":11,"nctId":204,"briefTitle":205,"officialTitle":206,"acronym":207,"eligibilityCriteria":208,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":209,"targetDuration":4,"studyType":23,"phases":211,"briefSummary":212,"conditions":213,"keywords":214,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":218,"lastUpdatePostDateStruct":219,"startDateStruct":221,"completionDateStruct":223,"leadSponsor":225,"locationsCount":4},"100603455","biotencer-biofeedback-as-preventive-treatment-in-tension-type-headache-100603455","NCT07136740","BioTenCer: Biofeedback as Preventive Treatment in Tension Type Headache","BioTenCer: a Randomized, Wait-list Controlled Study to Assess the Safety and Efficacy of the Cerebri-biofeedback Device as Preventive Treatment in Adult Participants With Frequent and Chronic Tension Type Headache.","BioTenCer","Inclusion Criteria:\n\n* 18 years of age inclusive or older, at the time of signing the informed consent.\n* A diagnosis of TTH according to the criteria of the International Classification of Headache Disorders 3rd edition (ICHD-3)\n* History of at least 6 days or more with TTH per 28-day period in the 3 months prior to screening (as recalled by the subject).\n* Frequency of at least 6 days or more with TTH per 28-day period, confirmed by daily diary entries in the baseline period.\n* At least three months of experience with smartphone and access to an iOS or Android phone at home.\n* Capability of giving signed informed consent which includes compliance with the requirements and restrictions listed in the informed consent form (ICF) and in this protocol.\n* Onset of TTH (and migraine, if present) before the age of 50 years.\n* The onset of TTH should be present for at least 1 year prior to inclusion.\n\nExclusion Criteria:\n\n* Subject does not master a Scandinavian language at a level sufficient to fully understand the written and verbal study information.\n* Subject is unable to differentiate TTH from other concomitant headaches.\n* A history of more than 1 migraine attack per month on average in the last year, as recalled by the patient.\n* Frequency of more than 1 migraine attack per month during the baseline period, as confirmed by daily diary entries.\n* Subjects diagnosed with trigeminal autonomic cephalalgias and cranial neuralgias.\n* Subjects with secondary headache conditions with the exception of medication overuse headache (MOH) as defined in the ICHD-3 criteria that undergo a successful 8 weeks acute medication stop, and does not overuse medication in the following 28 day period.\n* Use of concurrent TTH preventive medication, with the exception of stable dose (≥3 months or 5 half-lives, whichever is longer) monotherapy of TTH preventive medication.\n* Use of prophylactic medication with known prophylactic effect on other headache disorders, whatever the indication, with the exception of stable dose (≥3 months or 5 half-lives, whichever is longer) monotherapy of any preventive medication.\n* Subjects taking opioids (\\>3 days per month) or barbiturates at the time of screening.\n* Reduced sensibility, hearing or vision to a degree that impairs proper use of the app.\n* Patients with comorbid psychiatric disorders with psychotic or other symptoms making compliance with the study protocol difficult, at the discretion of the investigator.\n* Patients exhibiting a high degree of comorbidity and\u002For frailty associated with reduced life expectancy or high likelihood of hospitalization, at the discretion of the investigator.\n* Use of non-pharmacological preventive treatment, that in the opinion of the investigator is likely to interfere with the evaluation of the biofeedback treatment strategy under investigation. Stable non-pharmacological treatments for other indications than TTH that is not likely to interfere, is allowed if it is kept unaltered during study participation.\n* Previous or current use of biofeedback equipment.\n* Other pain conditions, not intended to be treated in this study, that in the opinion of the investigator could interfere with study procedures, accurate pain reporting, and\u002For confound evaluation of study endpoints\n* High probability neurological deterioration due to other medical conditions, that in the opinion of the investigator may confound outcome assessment.\n* Have within 6 months of enrolment a significant untreated addiction to dependency-producing medications, alcohol, or illicit drugs.\n* Abnormal pain behaviour, inappropriate medication-use and\u002For unresolved psychiatric illness, that in the opinion of the investigator are significant enough to impact perception of pain, compliance with intervention and\u002For ability to evaluate treatment outcome.\n* Subject is currently participating or planning to participate in another clinical investigation.\n* Subject who is unlikely to follow Clinical Investigation Plan or where treatment seems futile in the opinion of the Investigator or have demonstrated an inability to sufficiently adhere to headache diary entries (\\\u003C70%).\n\nThis study excludes patients with more than 1 migraine attack per month. A migraine attack is defined according to ICHD-3 criteria as attacks of unilateral, pulsating, moderate or severe headache lasting 4-72 hours that is aggravated by physical activity, associated with nausea and\u002For photophobia and phonophobia, and, in some cases, preceded by unilateral, fully-reversible central nervous system symptoms.",{"count":210,"type":22},300,[25],"The purpose of this study is to test a therapist-independent home-based smartphone app-based biofeedback treatment in adults with tension type headache. The aim of the study is to assess the safety and performance of the Cerebri-TTH biofeedback device as a preventive treatment in adults with frequent and chronic tension type headache.\n\nThe primary endpoint of the study is the change in the mean Area-Under-the-headache-Curve (AUC) from baseline to the last 28-day period during the treatment phase, in the treatment group as compared to the placebo group.",[35],[215,216,217],"biofeedback","tension type headache","therapist independent treatment","2025-08-21",{"date":220,"type":41},"2025-08-22",{"date":222,"type":22},"2025-09-01",{"date":224,"type":22},"2027-12",{"name":226,"class":48},"Helse Nord-Trøndelag HF",{"id":228,"slug":229,"hasResults":11,"nctId":230,"briefTitle":231,"officialTitle":231,"acronym":232,"eligibilityCriteria":233,"healthyVolunteers":234,"sex":17,"minAge":235,"maxAge":236,"enrollmentInfo":237,"targetDuration":238,"studyType":159,"phases":4,"briefSummary":239,"conditions":240,"keywords":246,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":249,"lastUpdatePostDateStruct":250,"startDateStruct":252,"completionDateStruct":254,"leadSponsor":256,"locationsCount":49},"100434650","china-headache-and-vertigo-registry-study-100434650","NCT04939922","China Headache and Vertigo Registry Study","CHRS","Inclusion Criteria:\n\n* Written informed consent and participant privacy information (eg, Written Authorization for Use and Release of Health and Research Study Information) obtained from the participant prior to initiation of any study-specific procedures.\n* Male or female participants ages 4 to 99 years.\n* Headache patients meeting the diagnostic criteria for ICHD-3, including primary headaches such as migraine and tension tension-type headaches, secondary headaches.\n* Patients who meet the headache diagnosis in the ICHD-3 appendix (including vestibular migraine).\n\nExclusion Criteria:\n\n* Patients who were unable to complete scales such as headache diary.\n* Patients denied or unable to be admitted for long-term follow-up.",true,"4 Years","99 Years",{"count":157,"type":22},"30 Years","In the Chinese Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type headache), vertigo (vertigo diseases such as vestibular migraine) and chronic pain (fibromyalgia and other diseases) were collected. The biomarkers, imaging features, right-to-left shunt of the heart (lung), genetic characteristics, treatment, and outcome (in relation to other diseases) of headache-related diseases were studied, and long-term follow-up was planned.",[162,241,163,30,242,243,244,245],"Headache Disorders, Secondary","Cluster Headache","Vertigo, Constant","Vestibular Migraine","Fibromyalgia",[163,247,248,244,245],"Headache Disorders","Vertigo","2025-07-22",{"date":251,"type":41},"2025-07-25",{"date":253,"type":41},"2017-06-12",{"date":255,"type":22},"2050-12-12",{"name":257,"class":48},"Second Affiliated Hospital, School of Medicine, Zhejiang University",{"id":259,"slug":260,"hasResults":11,"nctId":261,"briefTitle":262,"officialTitle":263,"acronym":4,"eligibilityCriteria":264,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":265,"targetDuration":4,"studyType":159,"phases":4,"briefSummary":267,"conditions":268,"keywords":270,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":276,"lastUpdatePostDateStruct":277,"startDateStruct":279,"completionDateStruct":280,"leadSponsor":282,"locationsCount":4},"100596643","turkish-version-of-the-headache-screening-questionnaire-100596643","NCT07048132","Turkish Version of the Headache Screening Questionnaire","Validity and Reliability of the Turkish Version of the Headache Screening Questionnaire","Inclusion Criteria:\n\n* Individuals aged 18 and over who present with headache complaints (migraine or tension-type) and voluntarily agree to participate\n\nExclusion Criteria:\n\n* Individuals with severe psychiatric disorders, illiteracy in Turkish, or significant cognitive impairment preventing comprehension of the scale",{"count":266,"type":22},200,"This multi-center, nationwide study aims to evaluate the validity and reliability of the Turkish version of the Headache Screening Questionnaire (HSQ-TR). The 10-item questionnaire is designed to screen for migraine and tension-type headache in individuals with headache complaints.\n\nParticipants presenting with headache will be enrolled. Each participant will first complete the HSQ-TR and then be examined by a neurologist who will provide a diagnosis according to the ICHD-3 beta criteria. The questionnaire results will be compared with the neurologist's diagnoses to assess criterion validity, including sensitivity, specificity, and agreement.",[163,35,269],"Headache",[271,216,272,273,274,275],"migraine","headache","headache screening questionare","validation","reliability","2025-07-11",{"date":278,"type":41},"2025-07-15",{"date":278,"type":22},{"date":281,"type":22},"2025-12-15",{"name":283,"class":284},"Başakşehir Çam & Sakura City Hospital","OTHER_GOV",{"id":286,"slug":287,"hasResults":11,"nctId":288,"briefTitle":289,"officialTitle":290,"acronym":4,"eligibilityCriteria":291,"healthyVolunteers":11,"sex":17,"minAge":292,"maxAge":4,"enrollmentInfo":293,"targetDuration":4,"studyType":23,"phases":295,"briefSummary":296,"conditions":297,"keywords":298,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":302,"lastUpdatePostDateStruct":303,"startDateStruct":305,"completionDateStruct":307,"leadSponsor":309,"locationsCount":49},"100573389","carotid-sinus-massage-in-trendelenburg-position-for-headache-relief-100573389","NCT06745648","Carotid Sinus Massage in Trendelenburg Position for Headache Relief","Effectiveness of Carotid Sinus Massage in Modified Trendelenburg Position for Acute Headache Episodes: A Pilot Study","INCLUSION CRITERIA:\n\n* Participants must be at least 16 years of age.\n* Must have a diagnosis of one of the following, according to the International Classification of Headache Disorders (ICHD-3):\n\n  * Migraine\n  * Tension-type headache\n  * Mixed headache\n* The headache episode must have started within the past 24 hours.\n\nEXCLUSION CRITERIA:\n\n* Any contraindication to carotid sinus massage, including:\n\n  * Carotid bruits\n  * Recent myocardial infarction\n  * History of stroke\n  * Known or suspected carotid artery stenosis\n* Any contraindication to the Trendelenburg position, including:\n\n  * Increased intracranial pressure\n  * Respiratory distress\n  * Congestive heart failure\n  * History of syncope\n  * History of cardiac arrhythmias","16 Years",{"count":294,"type":22},18,[25],"Headaches significantly impact patients' quality of life, with tension-type headaches and migraines being among the most prevalent types. There is growing evidence suggesting that blood pressure regulation and baroreceptor activity play a role in headache pathophysiology. Carotid sinus massage (CSM), particularly when combined with the modified Trendelenburg position, may modulate autonomic nervous system activity to relieve headache symptoms.\n\nAn initial open-label pilot study (n = 17) was completed, and the results were published in a preprint server for health sciences, the Medical Research Archive (medRxiv), demonstrating the feasibility, safety, and promising preliminary efficacy of CSM+T. Based on these findings, a follow-up randomized, sham-controlled, parallel-arm trial will further evaluate the efficacy of the treatment.",[163,30],[299,300,301],"Carotid Sinus Massage","Trendelenburg","Autonomic Nervous System","2025-06-11",{"date":304,"type":41},"2025-06-15",{"date":306,"type":41},"2024-12-21",{"date":308,"type":22},"2025-12-30",{"name":310,"class":48},"Hospital Municipal Pedro T. Orellana",{"id":312,"slug":313,"hasResults":11,"nctId":314,"briefTitle":315,"officialTitle":316,"acronym":317,"eligibilityCriteria":318,"healthyVolunteers":234,"sex":17,"minAge":235,"maxAge":236,"enrollmentInfo":319,"targetDuration":321,"studyType":159,"phases":4,"briefSummary":322,"conditions":323,"keywords":324,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":325,"lastUpdatePostDateStruct":326,"startDateStruct":328,"completionDateStruct":330,"leadSponsor":332,"locationsCount":49},"100471387","international-headache-registry-study-100471387","NCT05418218","International Headache Registry Study","International Headache and Vertigo Registration Study","IHRS","Inclusion Criteria:\n\nThe following are requirements for entry into the study:\n\n1. Written informed consent and participant privacy information (eg, Written Authorization for Use and Release of Health and Research Study Information) obtained from the participant prior to initiation of any study-specific procedures.\n2. Male or female participants ages 4 to 99 years, inclusive, at Visit 1.\n3. Headache patients meeting the diagnostic criteria for ICHD-3, including primary headaches such as migraine and tension tension-type headaches, secondary headaches, and patients who meet the headache diagnosis in the ICHD-3 appendix (including vestibular migraine).\n\nExclusion Criteria:\n\n1. Patients who were unable to complete scales such as headache diary.\n2. Patients denied or unable to be admitted for long-term follow-up.",{"count":320,"type":22},200000,"60 Years","In the International Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type headache), vertigo (vertigo diseases such as vestibular migraine) and chronic pain (fibromyalgia and other diseases) were collected. The biomarkers, imaging features, right-to-left shunt of the heart (lung), genetic characteristics, treatment, and outcome (in relation to other diseases) of headache-related diseases were studied, and long-term follow-up was planned.",[162,241,163,30,248,244,245],[163,247,248,244,245],"2025-05-19",{"date":327,"type":41},"2025-05-23",{"date":329,"type":41},"2021-07-12",{"date":331,"type":22},"2082-12-31",{"name":257,"class":48},{"id":334,"slug":335,"hasResults":11,"nctId":336,"briefTitle":337,"officialTitle":338,"acronym":4,"eligibilityCriteria":339,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":340,"targetDuration":4,"studyType":23,"phases":342,"briefSummary":343,"conditions":344,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":345,"lastUpdatePostDateStruct":346,"startDateStruct":348,"completionDateStruct":350,"leadSponsor":352,"locationsCount":49},"100409301","hvlat-electric-dn-exercise-vs-mobilization-stm-exercise-tens-for-tension-type-headaches-100409301","NCT04609709","HVLAT, Electric DN, Exercise Vs. Mobilization, STM, Exercise, TENS for Tension Type Headaches","Thrust Manipulation, Electric Dry Needling and Exercise Vs. Non-thrust Mobilization, Soft-Tissue Mobilization, Exercise and TENS for Tension Type Headache Sufferers","Inclusion Criteria:\n\n* Patient must be between 18 and 65 years old and report ALL YES under one of the Tension-type Headaches described below:\n\n2.2 Frequent Episodic Tension-type Headaches: Frequent episodes of headache, typically bilateral, pressing or tightening in quality and of mild to moderate intensity, lasting minutes to days. The pain does not worsen with routine physical activity and is not associated with nausea, but photophobia or phonophobia may be present.\n\n1. At least 10 episodes of headache occurring on 1- 14 days per month on average for \\>3 months (12 and \\\u003C180 days per year)\n2. Headache lasting from 30 minutes to 7 days\n3. Patient has headaches that have at least two of the following four characteristics:\n\n   1. Bilateral location\n   2. Pressing or tightening (non-pulsating) quality\n   3. Mild or moderate intensity\n   4. Not aggravated by routine physical activity such as walking or climbing stairs\n4. Both of the following are true:\n\n   1. No nausea or vomiting\n   2. No more than one of photophobia or phonophobia\n\n2.2.1 Frequent Episodic Tension-type Headache associated with pericranial tenderness\n\n1. Episodes fulfilling criteria for Frequent episodic tension-type headache (See 2.2 above)\n2. Increased pericranial tenderness on manual palpation.\n\n2.3 Chronic Tension-type Headaches: A disorder evolving from frequent episodic tension-type headache, with daily or very frequent episodes of headache, typically bilateral, pressing or tightening in quality and of mild to moderate intensity, lasting hours to days, or unremitting. The pain does not worsen with routine physical activity, but may be associated with mild nausea, photophobia or phonophobia.\n\n1. Headache occurring on 15 days per month on average for \\>3 months (180 days per year)\n2. Headache lasting hours to days, or unremitting\n3. At least two of the following four characteristics\n\n   1. Bilateral location\n   2. Pressing or tightening (non-pulsating) quality\n   3. Mild or moderate intensity\n   4. Not aggravated by routine physical activity such as walking of climbing stairs\n4. Both of the following:\n\n   1. No more than one of the photophobia, phonophonbia, or mild nausea\n   2. Neither moderate or severe nausea nor vomiting\n\n2.3.1 Chronic Tension-type Headache associated with pericranial tenderness\n\n1. Headache fulfilling criteria for 2.3 Chronic tension- type headache\n2. Increased pericranial tenderness on manual palpation.\n\nExclusion Criteria:\n\nExclusion Criteria: Must all be NO to be eligible\n\n1. Patient presents with other primary and\u002For secondary headache\n2. Patient presents with Medication Overuse Headache defined as:\n\n   1. Headache occurring on 15 days per month in a patient with a pre-existing headache disorder\n   2. Regular overuse for \\>3 months of one of more drug that can be taken for acute and\u002For symptomatic treatment of headache\n   3. Not better accounted for by another headache diagnosis\n3. History of head\u002Fneck trauma (to include whiplash)\n4. History of Cervical Stenosis\n5. Presence of any of the following atherosclerotic risk factors: hypertension, diabetes, heart disease, stroke, transient ischemic attack, peripheral vascular disease, smoking, hypercholesterolemia or hyperlipidemia\n6. Red flags noted in the patient's Neck Medical Screening Questionnaire (i.e. tumors, fracture, metabolic diseases, RA, osteoporosis, history of prolonged steroid use, etc.\n7. Bilateral upper extremity symptoms\n8. Evidence of CNS involvement, to include hyperreflexia, sensory disturbances in the hand, intrinsic muscle wasting of the hands, unsteadiness during walking, nystagmus, loss of visual acuity, impaired sensation of the face, altered taste, presence of pathological reflexes (i.e. positive Hoffman's and\u002For Babinski reflexes).\n9. Two or more positive neurologic signs consistent with nerve root compression, including any 2 of the following:\n\n   1. Muscle weakness involving a major muscle group of the upper extremity.\n   2. Diminished UE deep tendon reflex of the biceps, brachioradialis, triceps or superficial flexors\n   3. Diminished or absent sensation to pinprick in any UE dermatome.\n10. Prior surgery to neck of thoracic spine\n11. Involvement in litigation or worker's compensation regarding their neck pain and\u002For headaches\n12. Diagnosis of fibromyalgia syndrome\n13. Received anesthetic blocks or botulinum toxin within the previous 6 months\n14. Received physical treatment in the neck and head the previous 6 months\n15. Any condition that might contraindicate spinal manipulative therapy\n16. Pregnancy",{"count":341,"type":22},110,[25],"The purpose of this research is to compare two different approaches for treating patients with tension-type headaches: thrust Manipulation, electric dry Needling and exercise Vs. non-thrust mobilization, soft-tissue mobilization, exercise and TENS. Physical therapists commonly use all of these techniques to treat tension-type headaches. This study is attempting to find out if one treatment strategy is more effective than the other.",[30],"2025-05-14",{"date":347,"type":41},"2025-05-18",{"date":349,"type":41},"2020-10-31",{"date":351,"type":22},"2026-05-01",{"name":353,"class":48},"Alabama Physical Therapy & Acupuncture",{"id":355,"slug":356,"hasResults":11,"nctId":357,"briefTitle":358,"officialTitle":358,"acronym":4,"eligibilityCriteria":359,"healthyVolunteers":11,"sex":17,"minAge":360,"maxAge":361,"enrollmentInfo":362,"targetDuration":4,"studyType":23,"phases":364,"briefSummary":365,"conditions":366,"keywords":368,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":370,"lastUpdatePostDateStruct":371,"startDateStruct":373,"completionDateStruct":375,"leadSponsor":377,"locationsCount":49},"100586878","assessment-of-the-effectiveness-of-virtual-reality-as-a-learning-tool-for-relaxation-techniques-in-reducing-pediatric-migraines-and-tension-type-headache-100586878","NCT06921109","Assessment of the Effectiveness of Virtual Reality as a Learning Tool for Relaxation Techniques in Reducing Pediatric Migraines and Tension Type Headache","Inclusion Criteria:\n\n* Having a history of headaches for at least 6 months, or having been diagnosed with migraines and\u002For chronic tension-type headaches according to the criteria of the International Headache Society (IHS) by a pediatric neurologist.\n\nExclusion Criteria:\n\n* having an epilepsy disorder","8 Years","15 Years",{"count":363,"type":22},60,[25],"The goal of this interventional study is to assess the efficacy of a therapeutic intervention aimed at diminishing pediatric chronic headache. This intervention is based on the development of relaxation skills, particularly the practice of deep breathing, using virtual reality in conjunction with a biofeedback device. Specifically, it aims to assess the relevance of this tool both in learning relaxation techniques and in changing cognitions involved in pain adjustment, such as self-efficacy and pain catastrophizing.\n\nThe main hypothesis is that the intervention using virtual reality will lead to greater daily use of the relaxation techniques learned, as well as an increase in the associated self-efficacy, resulting in a reduction in headaches (in terms of frequency and intensity) both immediately after the intervention and two months later.\n\nA secondary hypothesis is that this intervention will contribute to a decrease in negative pain perceptions, pain catastrophizing, and functional disability.\n\nA tertiary hypothesis is that the intervention will lead to an improvement in the child's quality of life.\n\nThe effects of this intervention will be compared to those of a similar intervention without the use of virtual reality, as well as to a control condition in which only psychoeducation is provided.",[367,163,35],"Chronic Headache",[369],"Virtual Reality","2025-04-07",{"date":372,"type":41},"2025-04-10",{"date":374,"type":41},"2024-12-13",{"date":376,"type":22},"2027-12-31",{"name":378,"class":48},"University of Liege",{"id":380,"slug":381,"hasResults":11,"nctId":382,"briefTitle":383,"officialTitle":384,"acronym":4,"eligibilityCriteria":385,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":321,"enrollmentInfo":386,"targetDuration":4,"studyType":23,"phases":387,"briefSummary":388,"conditions":389,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":392,"lastUpdatePostDateStruct":393,"startDateStruct":395,"completionDateStruct":397,"leadSponsor":399,"locationsCount":49},"100570141","suboccipital-release-versus-instrument--assisted-soft-tissue-mobilization-on-tension-type-headache-100570141","NCT06703385","Suboccipital Release Versus Instrument- Assisted Soft Tissue Mobilization on Tension Type Headache","Effect of Suboccipital Release Versus Instrument- Assisted Soft Tissue Mobilization on Tension Type Headache","Inclusion Criteria:\n\n1. Participants of both gender will be between the ages of 18 and 60.\n2. Episodic tension type headache criteria, according to the International Headache Society's Headache Classification Committee., have at least two of the following characteristics.\n\n   * Recurrent episodes of headache on less than 15 days per month for at least 3 months\n   * Headache that last for from around 30 min till seven days.\n   * At least 2 of the following features are found in a headache:\n   * A location that is on two sides.\n   * Tightening\u002Fpressing quality (non-pulsating).\n   * Intensity is mild to moderate.\n   * Both of the following: Not worsened by routine physical activity, there is no nausea or vomiting.\n   * Only have one photophobia\u002F phonophobia\n3. Patients have active trigger points in suboccipital muscle and upper trapezius muscle\n4. The presence of myofascial trigger points was determined by therapist using the diagnostic criteria described by Simons .,(1999) ,The major criteria of active myofascial trigger points were: Regional neck pain, Pain or altered sensation in the expected distribution of referred pain from a myofascial trigger point, Taut band palpable in an accessible muscle.\n\nExclusion Criteria:\n\n1. Patients who have had a history of cancer\n2. Patients who have had cervical and cranial surgery\n3. Patients with severe psychological disorders (major Depression)\n4. Patients with uncontrolled hypertension\n5. Dysfunctions in the tempo-mandibular joint\n6. Headaches associated with high fever, stiff neck, or rash, problems of vision or profound dizziness\n7. Female who are pregnant or lactating",{"count":363,"type":22},[25],"The study aims to explore the impact of suboccipital release versus instrument-assisted soft tissue mobilization on pain intensity, pressure pain threshold, headache impact test, and headache frequency in patients with tension headache. The research will also examine the effects of these methods on headache impact tests and frequency.",[390,391,30],"Suboccipital Release","Instrumental Assisted Soft Tissue Mobilization","2024-11-25",{"date":394,"type":41},"2024-11-27",{"date":396,"type":22},"2024-12-01",{"date":398,"type":22},"2025-04-01",{"name":400,"class":48},"Cairo University",{"id":402,"slug":403,"hasResults":11,"nctId":404,"briefTitle":405,"officialTitle":406,"acronym":407,"eligibilityCriteria":408,"healthyVolunteers":234,"sex":17,"minAge":57,"maxAge":409,"enrollmentInfo":410,"targetDuration":4,"studyType":23,"phases":411,"briefSummary":412,"conditions":413,"keywords":414,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":419,"lastUpdatePostDateStruct":420,"startDateStruct":422,"completionDateStruct":424,"leadSponsor":426,"locationsCount":4},"100564717","effectiveness-of-deep-cervical-flexor-muscle-exercises-in-patients-with-tension-type-headache-100564717","NCT06632808","Effectiveness of Deep Cervical Flexor Muscle Exercises in Patients With Tension-Type Headache","Effects of Deep Cervical Flexor Muscle Exercises on Pain, Spinal Posture, and Sensory Sensitivity in Patients With Tension-Type Headache: A Single-Blind Randomized Controlled Trial","Single-Blind","Inclusion Criteria:\n\n* being diagnosed with tension-type headache\n\nExclusion Criteria:\n\n* whiplash injury,\n* significant neck trauma (caused by trauma to the neck, fracture, distortion, or violent attack that have caused the current NP),\n* nerve root compression of the cervical spine,\n* persistent headache attributed to traumatic injury to the head\n* cluster headache,\n* trigeminal neuralgia,\n* pregnancy,\n* breastfeeding,\n* severe physical and\u002For mental illness","50 Years",{"count":187,"type":22},[25],"The aim of this study is to evaluate the effects of deep cervical flexor muscle exercises on pain, spinal posture, and sensory sensitivity in patients with tension-type headaches. Designed as a single-blind randomized controlled trial, the study will assess participants' pain levels using the Visual Analog Scale (VAS), sensory sensitivity through the Sensory Sensitivity Scale, and spinal posture via a digital inclinometer for objective measurements. This research seeks to determine the effectiveness of these exercises in managing pain, improving spinal posture, and contributing to the enhancement of sensory sensitivity.",[30],[415,416,417,418],"Tension-type headache","Pain","Posture","sensory sensitivity","2024-10-07",{"date":421,"type":41},"2024-10-09",{"date":423,"type":22},"2024-11-18",{"date":425,"type":22},"2025-01-31",{"name":427,"class":48},"Muş Alparslan University",{"id":429,"slug":4,"hasResults":11,"nctId":430,"briefTitle":431,"officialTitle":432,"acronym":433,"eligibilityCriteria":434,"healthyVolunteers":234,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":435,"targetDuration":4,"studyType":23,"phases":437,"briefSummary":438,"conditions":439,"keywords":442,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":443,"lastUpdatePostDateStruct":444,"startDateStruct":446,"completionDateStruct":448,"leadSponsor":449,"locationsCount":49},"100523813","NCT06100588","The Classification and Treatment of Myofascial Headache: a Cross-sectional Study and Randomized Controlled Trial.","The Classification of Myofascial Headache: a Cross-sectional Study. the Added Value of Dry Needling in the Treatment of Myofascial Headache: a Randomized Controlled Trial.","COMPHAS_RCT","Inclusion Criteria:\n\n* \\\u003C 15 headache days per month\n* \\> 5 episodes of the headache that gives hindrance\n* Mean NPRS score for headache episodes \\>2\u002F10\n* No history of whiplash\n* No serious structural pathology\n* No previous surgeries in the head\u002Fneck\u002Fshoulder region\n\nTo be included in the RCT-part of the study:\n\n\\- Fitting the ICHD criteria for MFH\n\nExclusion Criteria:\n\n* Diagnosis of migraine by a neurologist or as confirmed via the Headache Screening Questionnaire (HSQ) with the maximum score of 8\u002F8.\n* Chronic headache (\\>15 headache days\u002Fmonth)\n* Newly onset headache (\\\u003C5 previous episodes of new headache type)\n* Whiplash or whiplash associated disorders\n* Serious structural pathology (confirmed by medical imaging)\n* Pain on both sides of the body, above and under the waist, (with a total score of 7 or more out of 10) (=Widespread pain)\n* Cardiovascular\u002Fmetabolic\u002Fsystemic\u002Fneurological diseases\n* Fibromyalgia, Chronic Fatigue Syndrome\n* History of surgery in the head\u002Fneck or shoulder region\n* Probable or definite neuropathic pain (according to the classification of Finnerup et al.)\n* Traumatic onset of the complaints\n* Pregnancy\u002Fgiven birth\u002Fbreastfeeding in the preceding year\n* Psychiatric illnesses or depression diagnosed by a psychiatrist and currently treated by a psychiatrist and\u002For medication.\n* BMI \\>30\n\nFor all of RCT-patients, the following criteria will also lead to exclusion due to the dry needling intervention:\n\n* Usage of heavy blood thinners or anti-coagulants (e.g. Marcoumar, Marevan, Sintrom)\n* High risk of infection because of comorbidities (e.g. HIV, diabetes) or skin conditions in the neck region (e.g. psoriasis)\n* Epilepsy\n* Allergies for latex, nickel\n* Needle phobia",{"count":436,"type":22},152,[25],"This project comprises two studies; a cross-sectional study and a randomized controlled trial.\n\n1. The goal of the cross-sectional study is to compare multiple outcome parameters in different headache types: tension type (TTH), cervicogenic (CGH) and myofascial headache (MFH) as drafted by the International Classification of Headache Disorders (ICHD). Not only will these types be compared against each other, they will also be compared to healthy controls (HC).\n\n   The main research questions are:\n   * Are the criteria drafted by the International Classification of Headache Disorders (ICHD) discriminative for MFH?\n   * Are there differences between the headache types (and healthy controls) in pain \\& disability scores, range of motion (ROM), muscle strength, muscle elasticity and hyperalgesia (=pain pressure threshold, PPT)?\n\n   Participants will :\n   * Fill out questionnaires about their pain and disability;\n   * Be clinically investigated by a physiotherapist (anamnesis, inspection, examination of movement and structures of the neck and head);\n   * Undergo a testing battery including neck ROM, neck muscle strength \\& elasticity and PPT measurement of the C2 processus spinosus, the bilateral upper trapezius muscle and the tibialis anterior muscle of the dominant leg.\n2. The goal of this randomized controlled study is to investigate the additional effect of dry needling in the treatment of MFH patients, as compared to a treatment consisting of manual techniques only. The main question it aims to answer is:\n\n   * Does manual therapy combined with dry needling provide an additional effect on pain, disability and functional outcomes in MFH patients, as compared to manual therapy alone?\n\nAfter the baseline test (see part 1), participants with MFH will be randomly divided to receive 4 sessions over 4 weeks of MT or MT + DN. Hereafter, the baseline test is repeated at 1 week and 3 months post-treatment.",[30,440,441],"Cervicogenic Headache","Myofascial Headache",[131,130,269],"2024-09-04",{"date":445,"type":41},"2024-09-19",{"date":447,"type":41},"2023-12-06",{"date":224,"type":22},{"name":450,"class":48},"University Ghent",{"id":452,"slug":453,"hasResults":11,"nctId":454,"briefTitle":455,"officialTitle":456,"acronym":4,"eligibilityCriteria":457,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":91,"enrollmentInfo":458,"targetDuration":4,"studyType":23,"phases":460,"briefSummary":461,"conditions":462,"keywords":463,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":468,"lastUpdatePostDateStruct":469,"startDateStruct":471,"completionDateStruct":473,"leadSponsor":475,"locationsCount":49},"100550865","mulligan-mobilizations-versus-active-release-technique-in-tension-type-headache-100550865","NCT06452628","Mulligan Mobilizations Versus Active Release Technique in Tension-type Headache.","Effects of Mulligan Mobilizations Versus Active Release Technique on Pain, Range of Motion and Disability in Patients With Tension-Type Headache.","Inclusion Criteria:\n\n* Individuals aged 18-35 years.\n* Diagnosis of chronic tension-type headache according to the International Classification of --Headache Disorders (ICHD-3) criteria.\n* Baseline HDI from 10 and above, and NPRS score 3 and above.\n* No prior exposure to any of the two interventions (ART and Mulligan Mobilization).\n\nExclusion Criteria:\n\n* All other types of headaches.\n\n  * Individuals taking medications for headaches.\n  * Serious neurological or medical conditions that could affect the study outcomes.\n  * History of psychiatric disorders.\n  * Recent head or neck trauma or surgery.\n  * Contraindications for any of the two interventions.\n  * Participation in other headache management studies during the study period.",{"count":459,"type":22},33,[25],"Tension-type headaches, characterized by a dull, aching head pain, are one of the most prevalent forms of headache disorders worldwide. Although they are typically not associated with severe disability or neurological symptoms, they can significantly impact an individual's quality of life due to chronic pain and discomfort. Non-pharmacological interventions, such as manual therapy techniques, have gained prominence in headache management, offering potential relief and functional improvements for patients. This study aims to investigate the comparative effectiveness of two widely used manual therapy approaches, Mulligan mobilization and Active Release Technique (ART), in alleviating pain, reducing disability, and enhancing range of motion (ROM) in patients suffering from tension-type headaches. Understanding which technique offers superior outcomes is vital for optimizing headache management strategies.",[30],[30,464,465,466,467],"Mulligan Mobilizations","Active release technique","cervical spine","manual therapy","2024-06-06",{"date":470,"type":41},"2024-06-11",{"date":472,"type":22},"2024-06",{"date":474,"type":22},"2024-09",{"name":476,"class":48},"Riphah International University"]