[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"terminal-cancer\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:terminal-cancer":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,67,93],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100563375","digipall-a-trial-of-digital-patient-reported-outcome-and-biomarker-monitoring-in-palliative-care-100563375",false,"NCT06615349","DigiPall; a Trial of Digital Patient Reported Outcome and Biomarker Monitoring in Palliative Care","DigiPall; a Randomized Controlled Trial of Digital Patient Reported Outcome and Biomarker Monitoring in Palliative Care","Inclusion Criteria:\n\n* Patients with established diagnosis of a metastatic cancer\u002Fsevere illness with limited life expectancy receiving palliative care services\n* Estimated life expectancy \\\u003C24 months (physician's guess)\u002F \\>3 months\n* Karnofsky Index ≥ 50% \u002F ECOG≤ 2\n* Aged \\>18 years\n* Owns and uses a smartphone\n* Give written informed consent\n\nExclusion Criteria:\n\n* Patients under curative treatment\n* Relevant cognitive impairment","ALL","18 Years",{"count":19,"type":20},382,"ESTIMATED","INTERVENTIONAL",[23],"NA","The aim of this study is to test if a system consisting of a wearable device measuring heartbeats and steps, together with daily communication with a chatbot on the smartphone asking the patients about their symptoms and giving tips, can reduce unplanned hospital readmissions and improve well-being in advanced cancer and severely ill patients.",[26,27],"Terminal Illness","Terminal Cancer",[29,30,31,32,33,34],"Palliative Care","chatbot","wearable","PROMs","rehospitalisation","mobile health","RECRUITING","2025-07-07",{"date":38,"type":39},"2025-07-10","ACTUAL",{"date":41,"type":39},"2025-06-11",{"date":43,"type":20},"2027-09",{"name":45,"class":46},"David Blum","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":47},"100524411","differences-in-acceptability-of-music-therapy-sessions-played-live-compared-to-a-recording-thereof-100524411","NCT06108375","Differences in Acceptability of Music Therapy Sessions Played Live Compared to a Recording Thereof","Inclusion Criteria:\n\n* Age \\>18 years old\n* Capacity to provide informed consent\n* Patients with established diagnosis of a metastatic cancer\u002Fsevere illness with limited life expectancy on a palliative care ward at the University Hospital Zurich\n\nExclusion Criteria:\n\n• Inability to answer a questionnaire due to physical limitations as well as cognitive or linguistic reasons.",{"count":55,"type":20},25,[23],"The present study seeks to assess differences in feasibility and acceptability of music therapy played live and listening to a recording thereof at the palliative care ward of the University Hospital Zurich. As a secondary objective the investigators aim to extend the limited findings on the putative effect of music therapy in palliative care populations derived from objective measures of human autonomic response combined with subjective psychological outcomes to support evidence-based medicine. The investigators will implement a commercially available tracker, the wristband 287-2 by Corsano, to investigate multiple simultaneous biomarkers of autonomic response to music therapy and a recording thereof, such as heart rate, heart rate variability, electrodermal activity and distal body temperature.\n\nTo investigate subjective quality of life and psychological outcomes, the investigators will administer highly validated and widely used questionnaires, namely the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire 15 Palliative Care, the Edmonton Symptom Assessment System and the Hospital Anxiety and Depression Scale.",[26,27],{"date":60,"type":39},"2025-07-11",{"date":62,"type":39},"2023-10-24",{"date":64,"type":20},"2026-03",{"name":66,"class":46},"University of Zurich",{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":77,"phases":4,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":47},"100541437","exploring-indications-and-practices-of-administering-artificial-hydration-to-terminal-cancer-patients-in-taiwan-100541437","NCT06329856","Exploring Indications and Practices of Administering Artificial Hydration to Terminal Cancer Patients in Taiwan","Exploring Indications and Practices of Administering Artificial Hydration to Terminal Cancer Patients and Establishing Clinical Consensus Guideline in Taiwan","Inclusion Criteria:\n\n* Taiwan Academy of Hospice Palliative Medicine\n* Taiwan Society of Cancer Palliative Medicine\n* At least a year in training to take care of terminally ill patients\n* Have signed informed consent.\n\nExclusion Criteria:\n\n* No clinical experience in palliative care\n* Decline to sign informed consent",true,{"count":76,"type":20},1270,"OBSERVATIONAL","Background: The issue of artificial hydration for terminal cancer patients is a classic ethical dilemma in palliative care. It is a common practice especially when patients are incapable of oral intake; however, there is a lack of research on indications and practices for the provision of artificial hydration to terminal cancer patients in Taiwan. The investigators aim to conduct a nationwide survey of palliative care physicians on their indications (general or specific), and practices of providing artificial hydration to terminal cancer patients. With that understanding of reasoning and clinical practice, the investigators would further establish an indigenous, evidence-based consensus guideline to serve as a reference for physicians in Taiwan.\n\nMethods: The study is comprised of two parts. The first part is to conduct a nationwide survey of palliative and oncology care specialists with a questionnaire designed from literature reviews and principles of clinical ethics. After validation of the questionnaire, the investigators will e-mail it to members of the Taiwan Academy of Hospice Palliative Medicine and the Taiwan Society of Cancer Palliative Medicine. The primary outcome measure of the study is the indication and clinical practice of artificial hydration, and the secondary outcome is factors associated with the administration or withdrawal of hydration.\n\nThe second part is to establish a national consensus on clinical guidelines for administering artificial hydration, where the investigators will conduct a modified Delphi method for 6 rounds. Literature reviews will be first performed and 14 sessions of one-to-one interviews in Round 1 to develop a draft. Subsequent rounds comprise questionnaire surveys among all panelists, teleconferences and e-mail discussions among core members, and cancer patients\u002Fpatients' family discussions. Statistical criteria include median and disagreement scores according to the Inter-Percentile Range Adjusted for Symmetry. Items voted for by 70% or more panelists will be selected and formalized into a consensus guideline.\n\nExpected results: The investigators hypothesize that the indication to administer artificial hydration to the terminal cancer patient is multi-factorial and culturally based.\n\nConclusion: The establishment of a consensus guideline will help clinicians to make an appropriate decision from ethical, medical, cultural, and emotional factors and facilitate cancer patients to achieve a good quality of dying.",[27,80,81],"Hospice","Palliative Medicine",[83],"Artificial hydration","2025-02-12",{"date":86,"type":39},"2025-02-14",{"date":88,"type":39},"2024-08-15",{"date":90,"type":20},"2026-07",{"name":92,"class":46},"National Taiwan University Hospital",{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":97,"acronym":98,"eligibilityCriteria":99,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":100,"enrollmentInfo":101,"targetDuration":4,"studyType":21,"phases":103,"briefSummary":105,"conditions":106,"keywords":108,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":47},"100517542","phase-2-vitamin-c-to-quality-of-life-in-patients-with-terminal-stage-pancreatic-cancer-100517542","NCT06018896","Vitamin C to Quality of Life in Patients With Terminal Stage Pancreatic Cancer","PTCA199-4","Inclusion Criteria:\n\n* Ability to understand and the willingness to sign a written informed consent document.\n* Age ≥ 18 years and ≤ 80 years.\n* Eastern Cooperative Oncology Group (ECOG) performance status 0-2.\n* Histologically or cytologically confirmed metastatic pancreas adenocarcinoma.\n* Tumor progression after two lines of chemotherapy.\n* Adequate organ performance based on laboratory blood tests.\n* Presence of at least of one measurable lesion in agreement to Response Evaluation Criteria in Solid Tumours (RECIST) criteria.\n* The expected survival ≥ 1 months.\n* Women of childbearing potential and men must agree to use adequate contraception prior to study entry and for the duration of study participation.\n\nExclusion Criteria:\n\n* Active second primary malignancy or history of second primary malignancy.\n* The diagnosis was confirmed by pathology as non-adenocarcinoma of pancreas.\n* Inflammation of the digestive tract, including pancreatitis, cholecystitis, cholangitis, etc.\n* Pregnant or nursing women.\n* Glucose-6-phosphate dehydrogenase (G6PD) deficiency.\n* Severe and uncontrollable accompanying diseases that may affect protocol compliance or interfere with the interpretation of results.\n* Renal insufficiency or dialysis\n* Other serious accompanying illnesses, which, in the researcher's opinion, could seriously adversely affect the safety of the treatment.\n* Patients who are unwilling or unable to comply with study procedures.","80 Years",{"count":102,"type":20},20,[104],"PHASE2","The purpose of this study is to evaluate the efficacy of vitamin C in improving the quality of life for metastatic pancreatic cancer patients who are resistant to chemotherapy.",[107,27],"Metastatic Pancreatic Cancer",[109,110,111,112],"ascorbate","anemia","quality of life","chemotherapy","2024-06-05",{"date":115,"type":39},"2024-06-06",{"date":117,"type":39},"2023-08-25",{"date":119,"type":20},"2026-08-15",{"name":121,"class":46},"Fudan University"]