[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"therapy-induced-hot-flashes-in-breast-cancer-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:therapy-induced-hot-flashes-in-breast-cancer-patients":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100575638","phase-3-role-of-folic-acid-in-the-management-of-adjuvant-endocrine-therapy-induced-hot-flashes-in-breast-cancer-patients-100575638",false,"NCT06774885","ROLE OF FOLIC ACID IN THE MANAGEMENT OF ADJUVANT ENDOCRINE THERAPY-INDUCED HOT FLASHES IN BREAST CANCER PATIENTS","Inclusion Criteria:\n\n* Females older than 18 years\n* Diagnosed with confirmed breast cancer and currently treated with an adjuvant endocrine\n* Experiencing bothersome hot flashes at least 14 times\u002Fweek\n* Taking the treatment within 6 months to two years.\n\nExclusion Criteria:\n\n* Known hypersensitivity to folic acid\n* Patients who have been treated with selective serotonin reuptake inhibitors (SSRIs) within the past 30 days.\n* Renal impairment is defined as a serum creatinine level greater than 2 mg\u002Fld..\n* Significant liver disease: Indicated by liver enzyme levels exceeding two times the upper limit of normal.\n* Metastatic breast cancer\n* Taking other medication for hot flashes\n* Medications inducing hot flashes such as (Clomiphene, Opioids, Nifedipine, Prednisone)","FEMALE","18 Years","75 Years",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"PHASE3","The study's objective is to investigate the role of folic acid administration in the management of hot flashes associated with adjuvant endocrine therapy in patients with breast cancer.",[26],"THERAPY-INDUCED HOT FLASHES IN BREAST CANCER PATIENTS",[28,29,30,31],"Breast cancer","Hot flashes","Endocrine therapy","Folic acid","NOT_YET_RECRUITING","2025-01-09",{"date":35,"type":36},"2025-01-14","ACTUAL",{"date":38,"type":20},"2025-02-09",{"date":40,"type":20},"2025-08",{"name":42,"class":43},"Future University in Egypt","OTHER"]