[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"third-molar-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:third-molar-surgery":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,78],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100631260","comparative-analysis-of-fast-and-slow-absorbable-polylactose-co-glycolide-sutures-in-oral-surgery-a-randomized-controlled-trial-100631260",false,"NCT07498361","Comparative Analysis of fast-and Slow-absorbable Poly(Lactose-co-glycolide) Sutures in Oral Surgery: a Randomized Controlled Trial.","Inclusion Criteria:\n\n* non smoker patients\n* clinical indication to third molar surgical removal\n* patients who are able to express informed consent\n\nExclusion Criteria:\n\n* smokers\n* pregnant female\n* subjects treated with medications that affect bone metabolism",true,"ALL","18 Years",{"count":19,"type":20},27,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to compare slow-resorbing and fast-resorbing sutures used after the surgical extraction of lower third molars. Sutures are routinely placed after wisdom tooth removal to promote hemostasis. Slow-resorbing and fast-resorbing sutures differ mainly in how long they remain in place, and fast-resorbing sutures often do not require removal. The study evaluates whether these two types of sutures differ in terms of microbiological contamination. Patient-reported inflammation, swelling, and postoperative discomfort will also be assessed.\n\nEach participant will be randomly assigned to receive one of the two suture types. Only routine clinical procedures are involved. Participation includes several standard visits: initial medical and dental history collection with oral and radiographic examination; the surgical extraction of the lower third molar; suture removal at 7 days. No additional invasive procedures are required.\n\nParticipants will receive a daily diary to record pain levels and any pain medication taken during the first postoperative week. At the 7-day visit, wound healing will be evaluated and sutures will be removed, collected and anonymously analyzed by the University Microbiology Laboratory.\n\nThis study seeks to provide useful information about the clinical performance and microbiological behavior of different types of resorbable sutures commonly used in oral surgery, with the goal of improving patient care and postoperative outcomes.",[26,27,28],"Poly(Lactide-co-glycolide) Sutures","Suture Resorption","Third Molar Surgery",[30,31,32,33],"poly(lactide-co-glycolide) sutures","third molar surgery","microbial biofilm","suture resorption","RECRUITING","2026-03-30",{"date":37,"type":38},"2026-04-06","ACTUAL",{"date":40,"type":38},"2024-12-03",{"date":42,"type":20},"2027-01-01",{"name":44,"class":45},"University of Padova, School of Dental Medicine","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":21,"phases":57,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100571422","intraosseous-versus-submucosal-dexamethsone-injection-in-third-molar-surgery-100571422","NCT06720051","Intraosseous Versus Submucosal Dexamethsone Injection in Third Molar Surgery","Efficacy of Intraosseous Versus Submucosal Dexamethasone Injection in Terms of Pain, Facial Swelling and Interincisal Opening Among Patients Undergoing Third Molar Surgery","Inclusion Criteria:\n\n* Patients undergoing mandibular third molar surgery\n* Age 18 to 35 years\n* Male and female\n\nExclusion Criteria:\n\n* Uncontrolled systemic medical problems including diabetes and hypertension\n* Presence of any cyst, tumor, or other pathological condition in the molar area\n* Presence of any craniofacial anomalies, congenital deformities or syndromes\n* Patients with known adverse effects of steroid use\n* Previous history of orthodontic treatment\n* Have a pain disorder or taking pain medications\n* Pregnant and lactating mothers","35 Years",{"count":56,"type":20},76,[23],"The goal of this clinical trial is to learn if intraosseous dexamethasone injection is better for pain and swelling postop 3rd molar surgery than submucosal dexamethasone injection. The main questions it aims to answer are:\n\nDoes intraosseous dexamethasone injection provide better pain relief and lessen facial swelling than submucosal dexamethasone injection Does intraosseous dexamethasone injection provide better interincisal opening than submucosal dexamethasone injection Researcher will compare both the techniques to see if intraosseous dexamethasone injection works better than submucosal dexamethasone injection\n\nParticipants will:\n\nBe assessed at 3rd and 7th day postoperatively Pain will be assessed through visual analog scale score Facial measurement will be calculated as horizontal measurement plus vertical measurement divided by 2, where horizontal measurement will be taken as the distance between corner of the mouth and the earlobe attachment, and vertical measurement will be taken as distance from outer canthus of the eye to the angle of jaw.\n\nInterincisal opening will be measured from the incisal edge of the maxillary central incisors to the incisal edge of mandibular central incisors at the midline by using millimeter ruler",[28],[61,62,63,64,65,66],"intraosseous dexamethasone injection","submucosal dexamethasone injection","Third molar surgery","facial pain in third molar surgery","facial swelling in 3rd molar surgery","interincisal opening in third molar surgery","NOT_YET_RECRUITING","2024-12-09",{"date":70,"type":38},"2024-12-13",{"date":72,"type":20},"2025-06-01",{"date":74,"type":20},"2025-11-30",{"name":76,"class":77},"Services Institute of Medical Sciences, Pakistan","OTHER_GOV",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":16,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":21,"phases":90,"briefSummary":92,"conditions":93,"keywords":97,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":46},"100565304","early-phase-1-led-therapy-for-third-molar-surgery-100565304","NCT06640439","LED Therapy for Third Molar Surgery","LED Therapy Using 830 Nm in the Mandibular Third Molar Surgery: Double-blind Randomized Clinical Trial.","LTTMS","Inclusion Criteria:\n\n1. Healthy Asians;\n2. 20-55 years old;\n3. Having mandibular third molars that are inappropriately erupted and need to be extracted due to caries, orthodontic reasons and\u002For periodontal disease;\n\nExclusion Criteria:\n\n1. Underlying diseases: diabetes, cardiovascular disease, coagulation disorder, osteoporosis, hypertension, neurological disease, psychological disorder, tumor, systemic infection or cyst at the extraction site;\n2. Women who are preparing for pregnancy, pregnant or breastfeeding;\n3. Medication history: use of analgesics, anti-inflammatory drugs and\u002For antibacterial drugs 2 weeks before tooth extraction, need for systemic medication other than acetaminophen after surgery, allergy to acetaminophen, use of anticoagulants, bisphosphonates;\n4. Bad habits, such as addicted to smoking, drinking, etc.;\n5. Volunteers who have recently participated in other clinical trials;","20 Years","55 Years",{"count":89,"type":20},50,[91],"EARLY_PHASE1","LED Therapy for third molar surgery",[94,95,96,28],"Molar, Third","Photobiomodulation","Photobiomodulation Therapy",[98,99,100,31],"photobiomodulation","LED","830 nm","2024-10-10",{"date":103,"type":38},"2024-10-15",{"date":105,"type":20},"2024-10-14",{"date":107,"type":20},"2025-04-14",{"name":109,"class":45},"Huashan Hospital"]