[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"thoracic-epidural-analgesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:thoracic-epidural-analgesia":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,77],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100613941","combined-subcostal-and-lateral-transversus-abdominis-plane-block-for-postoperative-analgesia-versus-thoracic-epidural-analgesia-in-patients-undergoing-major-abdominal-cancer-surgery-100613941",false,"NCT07273136","Combined Subcostal and Lateral Transversus Abdominis Plane Block for Postoperative Analgesia Versus Thoracic Epidural Analgesia in Patients Undergoing Major Abdominal Cancer Surgery","Safety and Efficacy of Combined Subcostal and Lateral Transversus Abdominis Plane Block for Postoperative Analgesia Versus Thoracic Epidural Analgesia in Patients Undergoing Major Abdominal Cancer Surgery","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status I-III.\n* Scheduled for major abdominal surgeries including: (e.g., gastrectomy, colectomy, hepatectomy, cystectomy, total abdominal hysterectomy, Nephrectomy, pancreatectomy).\n\nExclusion Criteria:\n\n* Intraoperative hemodynamic instability.\n* History or evidence of coagulopathy.\n* Infection or abdominal wall masses at injection site.\n* Morbid obesity.\n* Other Medical conditions including mental illness or substance abuse.\n* Known allergy to local anesthetics.\n* Chronic opioid use or chronic pain conditions.\n* Pregnancy.","ALL","18 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to evaluate the safety and efficacy of combined subcostal and lateral transversus abdominis plane (TAP) for postoperative analgesia versus thoracic epidural anesthesia (TEA) in patients undergoing major abdominal cancer surgery.",[26,27,28,29,30,31],"Subcostal","Lateral","Transversus Abdominis Plane Block","Postoperative Analgesia","Thoracic Epidural Analgesia","Major Abdominal Cancer Surgery","RECRUITING","2025-12-10",{"date":35,"type":36},"2025-12-11","ACTUAL",{"date":33,"type":36},{"date":39,"type":20},"2026-04-01",{"name":41,"class":42},"Assiut University","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":53,"targetDuration":55,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":4},"100611266","analgesic-effectiveness-of-spsipb-versus-thoracic-epidural-and-systemic-opioid-analgesia-after-vats-spsipb-vats-100611266","NCT07238348","Analgesic Effectiveness of SPSIPB Versus Thoracic Epidural and Systemic Opioid Analgesia After VATS (SPSIPB-VATS)","Prospective Evaluation of Analgesic Outcomes of Serratus Posterior Superior Intercostal Plane Block Versus Thoracic Epidural Analgesia and Systemic Opioid Analgesia After Video-Assisted Thoracoscopic Surgery","SPSIPB-VATS","Inclusion Criteria:\n\n* Adults aged 18-75 years\n* Scheduled for elective video-assisted thoracoscopic surgery (VATS)\n* ASA physical status I-III\n* Ability to understand study procedures and provide written informed consent\n* Hemodynamically stable preoperatively\n\nExclusion Criteria:\n\n* Known allergy or contraindication to local anesthetics or study medications\n* Coagulopathy or use of anticoagulants not suitable for regional anesthesia\n* Local infection or skin lesions at the injection site\n* Severe pulmonary disease (e.g., severe COPD, uncontrolled asthma)\n* Chronic opioid use or chronic pain disorders\n* Neurological or psychiatric disorders impairing cooperation\n* Pregnancy or breastfeeding\n* BMI \\> 35 kg\u002Fm²\n* Conversion from VATS to thoracotomy\n* Inability to comply with postoperative assessments","75 Years",{"count":54,"type":20},120,"1 Day","OBSERVATIONAL","This prospective observational study aims to compare the postoperative analgesic effectiveness of three commonly used pain management strategies in video-assisted thoracoscopic surgery (VATS): Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Thoracic Epidural Analgesia (TEA), and systemic opioid analgesia. The study evaluates postoperative pain scores, opioid consumption, and the need for rescue analgesics within the first 24 hours after surgery. By analyzing analgesic performance and safety profiles of these techniques, the study seeks to provide evidence to guide optimal postoperative pain management for patients undergoing minimally invasive thoracic procedures.",[59,60,30,61],"Postoperative Pain Management","Video-assisted Thoracoscopic Surgery (VATS)","Serratus Posterior Superior Intercostal Plane Block",[61,30,63,64,65,66],"Systemic Opioid Analgesia","Video-Assisted Thoracoscopic Surgery","Opioid Consumption","Pain Management","NOT_YET_RECRUITING","2025-11-18",{"date":70,"type":36},"2025-11-20",{"date":72,"type":20},"2025-12-15",{"date":74,"type":20},"2026-08-15",{"name":76,"class":42},"Karadeniz Technical University",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":83,"minAge":17,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":21,"phases":87,"briefSummary":88,"conditions":89,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":43},"100584093","ultrasound-guided-multilevel-erectorspinae-plane-block-versus-thoracic-epidural-analgesia-for-prevention-of-post-mastectomy-pain-syndrome-for-breast-cancer-patients-100584093","NCT06884852","Ultrasound-guided Multilevel Erectorspinae Plane Block Versus Thoracic Epidural Analgesia for Prevention of Post Mastectomy Pain Syndrome for Breast Cancer Patients","Inclusion Criteria:\n\n* Female patients age ≥ 18 years and ≤ 65 Years.\n* Type of surgery; Modified Radical Mastectomy (MRM)\n* Physical status ASA II, III.\n* Body mass index (BMI): \\> 20 kg\u002Fm2 and \\\u003C 35 kg\u002Fm2.\n\nExclusion Criteria:\n\n* Patient refusal.\n* Allergy or a contraindication to the drug used in the study, e.g. local anesthetics, opioids.\n* History of psychological disorders.\n* History of chronic pain.\n* Contraindication to regional anesthesia e.g. sepsis, peripheral neuropathies and coagulopathy.\n* Advanced chronic renal disease, which is defined as a chronic kidney disease (CKD) in which there is a severe reduction in glomerular filtration rate (GFR \\\u003C 30 ml\u002Fmin) and includes stages 4 and 5 of the CKD classification.\n* Decompensated cirrhosis, which is defined as an acute deterioration in liver function in a patient with cirrhosis and is characterized by jaundice, ascites, hepatic encephalopathy, hepatorenal syndrome, or variceal hemorrhage.\n* Severe heart disease which is defined as NYHA class iii (moderate symptoms with less than normal activity, marked limitation of function status) or NYHA class IV (severe symptoms with features of heart failure with minimal activity or at rest and severe limitation of functional status)\n* Severe lung disease which includes oxygen saturation of blood less than 92%, RR more than 20, FEV1\u002FFVC ratio less than 60%.\n* Pregnancy.","FEMALE","65 Years",{"count":86,"type":20},44,[23],"The aim of this study is to compare the analgesic efficacy of multilevel erector spinae plane block (ESPB) vs thoracic epidural in modified radical mastectomy (MRM) regarding duration of analgesia, postoperative opioid consumption, effect on intraoperative fentanyl consumption, postoperative numerical pain rating scale and quality of life for the next 6 months.",[90,91,30,92,93,94],"Ultrasound","Multilevel Erector Spinae Plane Block","Post Mastectomy","Pain Syndrome","Breast Cancer Patients","2025-05-18",{"date":97,"type":36},"2025-05-21",{"date":99,"type":36},"2025-03-20",{"date":101,"type":20},"2026-03-01",{"name":103,"class":42},"National Cancer Institute, Egypt"]