[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"thumb-carpometacarpal-joint-osteoarthritis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:thumb-carpometacarpal-joint-osteoarthritis":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,75,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":74},"100636735","surgery-for-thumb-base-osteoarthritis-joint-replacement-vs-trapeziectomy-100636735",false,"NCT07569549","Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy","BASTION - BASe of Thumb Osteoarthritis Management Non-inferiority Trial: Surgical Treatment of First Carpometacarpal Joint Osteoarthritis: A Comparison Between Joint Replacement and Trapeziectomy","BASTION","Inclusion Criteria:\n\n* Age 40-80 years at inclusion\n* CMC-joint osteoarthritis grade 1-3 (Eaton-Littler classification)\n* Rest pain or pain reducing hand function with indication for surgery\n* Insufficient relief from non-operative treatment for ≥3 months (orthosis, OTC analgesics, cortisone injection)\n* Eligible for both prosthesis and trapezectomy per including surgeon\n* Non-smoker or complete smoking cessation ≥6 weeks prior to surgery\n\nExclusion Criteria:\n\n* Previous surgery to thumb base or STT-joint\n* Ongoing chronic pain condition\n* Dementia or cognitive impairment\n* Trapezium height \\\u003C7 mm on plain radiograph\n* Active smoker\n* Osteoarthritis grade 4 (Eaton-Littler)","ALL","40 Years","80 Years",{"count":21,"type":22},84,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint osteoarthritis.\n\nThe main questions it aims to answer are:\n\nDoes surgery with total joint arthroplasty provide better power grip and pinch grip strength compared to traditional surgery?\n\nWhat is the long-term risk of complications for both methods?\n\nWhich method is more cost-effective for the healthcare system?\n\nResearchers will compare total joint arthroplasty (TOUCH) to trapezectomy (a procedure where a bone in the thumb base is removed) to see which method provides the best results for the patient.\n\nParticipants will:\n\nBe randomized to undergo either an operation with total joint arthroplasty or a trapezectomy.\n\nUndergo an initial evaluation and a health economic cost analysis after one year.\n\nAttend follow-up checkups at 2, 5, and 10 years post-surgery to evaluate long-term function and the durability of the prosthesis.",[28,29,30,31],"Thumb Osteoarthritis","Thumb Carpometacarpal Joint Osteoarthritis","Carpometacarpal (CMC) Joint Arthritis","Basal Thumb Osteoartrithis",[33,34,35,36,37,38,39,28,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61],"Thumb base arthroplasty","CMC joint","prosthesis","hand surgery","First Carpometacarpal Joint","Trapeziometacarpal Joint","Rhizarthrosis","Dual Mobility Prosthesis","Total Joint Replacement","Total Joint Arthroplasty","Ligament Reconstruction","Surgical Reconstruction","Randomized Controlled Trial (RCT)","Prospective Studies","Comparative Study","Prospective Study","Cost-Effectiveness Analysis","Cost-Benefit Analysis","Health Economics","Patient Reported Outcome Measures (PROMs)","Quality of Life (QoL)","Health-Related Quality of Life (HRQoL)","Return to Work","Grip Strength","Pinch Strength","QuickDASH","EQ-5D","Michigan Hand Outcomes Questionnaire (MHQ","Trapeziectomy","RECRUITING","2026-06-22",{"date":65,"type":66},"2026-06-25","ACTUAL",{"date":68,"type":22},"2026-07-01",{"date":70,"type":22},"2038-03",{"name":72,"class":73},"Uppsala University","OTHER",2,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":17,"minAge":83,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":86,"phases":4,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":100},"100624157","touch-cmc-1-new-enrollment-us-study-100624157","NCT07405983","TOUCH® CMC 1 New Enrollment US Study","Effectiveness and Safety of the TOUCH® CMC 1 Prosthesis, Post-Approval Study","PAS002","Inclusion Criteria:\n\n1. Patient requiring 1st carpometacarpal (CMC) primary total joint replacement (arthroplasty) to surgically treat symptomatic Eaton-Littler Stage II or III osteoarthritis (OA)\n2. Adult (≥ 22 years of age) at the time of enrollment\n3. Willing and able to sign the study Informed Consent\n\nExclusion Criteria:\n\n1. Acute or chronic infections, local or systemic\n2. Muscular, neurological, or vascular severe deficiency affecting the joint\n3. Inadequate bone quality or quantity preventing the implant fixation\n4. Bones dimensions incompatible with implant sizes\n5. Patients who are allergic to the product's materials\n6. Any concomitant disorder that may affect the function of the implant (e.g., osteoarthritis of the wrist)\n7. Skeletally immature (i.e., pediatric population, \\\u003C22 years of age)\n8. Pregnant or nursing women\n9. Patients with contraindications to surgery in general\n10. Patients with an intellectual disability who cannot follow the instructions of their surgeon.","22 Years",{"count":85,"type":22},163,"OBSERVATIONAL","The purpose of this study is to meet a PMA (P240020) condition of approval of the TOUCH® CMC 1 Prosthesis to evaluate the effectiveness and safety of the prosthesis in the United States (US) population. The device performance in newly enrolled US patients implanted by US surgeons will be compared to device performance observed within the outside the US (OUS) premarket cohort.",[89,29],"Osteoarthritis Thumb","2026-06-02",{"date":92,"type":66},"2026-06-04",{"date":94,"type":66},"2026-03-04",{"date":96,"type":22},"2030-02",{"name":98,"class":99},"Keri Medical SA","INDUSTRY",4,{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":17,"minAge":107,"maxAge":108,"enrollmentInfo":109,"targetDuration":111,"studyType":86,"phases":4,"briefSummary":112,"conditions":113,"keywords":114,"overallStatus":118,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":4},"100639790","biomechanical-evaluation-with-finite-element-models-in-thumb-carpometacarpal-osteoarthitis-prospective-comparative-analysis-of-loads-in-arthroplasty-with-or-without-implants-100639790","NCT07614269","Biomechanical Evaluation With Finite Element Models in Thumb Carpometacarpal Osteoarthitis: Prospective Comparative Analysis of Loads in Arthroplasty With or Without Implants","Inclusion Criteria:\n\n* Primary Osteoarthritis in thumb CMC joint in the hand\n* Adults aged between 50 and 88 years old included.\n* Thumb CMC joint osteoarthritis, radiographic stages II, III and IV by Eaton- Littler classification (1973).\n\nExclusion Criteria:\n\n* Asymptomatic primary osteoarthritis in thumb CMC joint\n* Patients with osteoarthritis and age less than 50 years or more than 88 years.\n* Patients who have had previous interventions in the area, in this joint, injuries in this hand or fractures.\n* Patients with rheumatic diseases or collagen diseases that create joint instability.\n* Patients with physical or mental conditions that preclude intervention.\n* Thumb CMC joint osteoarthritis, radiographic stages I by Eaton-Littler classification (1973)","50 Years","88 Years",{"count":110,"type":22},40,"12 Months","To better understand the load distribution in the Thumb Carpometacarpal Joint (CMC joint) in presence of osteoarthritis and how surgery by means of a suspension-resection arthroplasty or a joint replacement by means of a metal prosthesis affects this load distribution. These studies allow to supporting medical decisions and surgical treatments results with biomechanical evidence.The clinical management of the patients will be adapted to the treatment standards of the Orthopedic Surgery and Traumatology Service of the Hospital de la Santa Creu i Sant Pau, without the performance of this study influencing this process.",[29],[115,116,117],"Thumb carpometacarpal joint osteoarthritis","carpometacarpal prosthesis","Thumb carpometacarpal arthroplasty","NOT_YET_RECRUITING","2026-05-25",{"date":121,"type":66},"2026-05-29",{"date":123,"type":22},"2026-06-15",{"date":125,"type":22},"2026-12-31",{"name":127,"class":73},"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau"]