[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"thumb-injury\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:thumb-injury":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,50,82,103],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100580365","registry-randomized-comparison-of-rehabilitation-regimens-after-flexor-tendon-injury-in-the-thumb-100580365",false,"NCT06836349","Registry-randomized Comparison of Rehabilitation Regimens After Flexor Tendon Injury in the Thumb","Registry-randomized Comparison of Rehabilitation Regimens After Flexor Pollicis Longus Injury in the Thumb","Inclusion Criteria:\n\nComplete laceration of the thumb flexor tendon (Flexor Pollicis Longus; FPL) within zone 1 and 2.\n\nAge over 15 years. Minors (\\\u003C18 years) are considered to have sufficient maturity to understand the implications of the research.\n\nSwedish-speaking \u002F able to understand spoken and written Swedish. Surgery performed within 14 days from the time of injury.\n\nExclusion Criteria:\n\nTendon injury with a defect requiring tendon grafting. Another complete tendon injury in the same hand. Extensive associated injuries, such as fracture, vascular injury with circulatory impairment, large skin defect, or preoperative signs of infection. Patient deemed unsuitable for early active motion therapy due to factors such as lack of cooperation, cognitive impairment, or substance abuse issues.\n\nPatient declines follow-up in the HAKIR quality registry. Wound infection making early active motion therapy inappropriate.","ALL","15 Years",{"count":19,"type":20},380,"ESTIMATED","INTERVENTIONAL",[23],"NA","Flexor tendon injuries in the thumb occur across all ages and genders. Each year, approximately 400 patients undergo surgery for a flexor tendon injury in Sweden. These injuries are exclusively treated at one of the seven specialized hand surgery clinics, as the surgery is technically demanding, and postoperative rehabilitation is critical, specialized, and requires expertise from hand therapists. To prevent tendon adhesions and stiffness in the thumb or fingers, controlled active motion therapy is usually initiated within a few days after surgery. Studies on finger flexor tendon injuries have shown that early active movement therapy leads to better mobility compared to immobilization. Consequently, early active training is now the standard treatment following flexor tendon repair. However, during postoperative rehabilitation, the repaired flexor tendon may rupture, often necessitating revision surgery.\n\nThe rupture rate after flexor tendon repair in the thumb is approximately three times higher than in other fingers (10% vs. 3%). While most studies on flexor tendon injuries focus on finger tendons, research on the outcomes of thumb flexor tendon injuries is limited. The biomechanics and anatomy of the thumb's flexor tendon differ significantly from those of finger tendons.\n\nThe objective of this study is to determine whether the rupture rate following thumb flexor tendon surgery can be reduced by immobilizing the thumb in a cast for four weeks postoperatively, compared to standard early active motion therapy, without negatively affecting joint mobility and thumb strength. Additionally, the study will evaluate patient-reported outcomes one year post-surgery for both rehabilitation regimens (immobilization vs. mobilization).\n\nThis study is a registry-randomized clinical trial (RRCT) involving five hand surgery clinics in Sweden. Data following randomization between the two rehabilitation protocols will be collected through follow-up in the Swedish National Hand Surgery Quality Registry (HAKIR).",[26,27,28,29],"Flexor Tendon Injury","Rehabilitation Program","Flexor Tendon Rupture","Thumb Injury",[31,32,33,34,35,36],"Flexor pollicis longus injury","RRCT","Early active motion","flexor tendon injury","Thumb","Immobilisation","RECRUITING","2026-05-31",{"date":40,"type":41},"2026-06-03","ACTUAL",{"date":43,"type":41},"2025-05-01",{"date":45,"type":20},"2031-12-31",{"name":47,"class":48},"Karolinska Institutet","OTHER",5,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":61,"studyType":62,"phases":4,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":81},"100622799","functional-improvement-and-fine-dexterity-in-thumb-tendon-injuries-100622799","NCT07388316","Functional Improvement and Fine Dexterity in Thumb Tendon Injuries","Investigation of the Relationship Between Functional Improvement and Changes in Fine Manual Dexterity in Isolated Thumb Tendon Injuries","Inclusion Criteria:\n\n* No history of neurological, orthopaedic, rheumatological, metabolic disease or surgery in the relevant extremity\n\nExclusion Criteria:\n\n* Comorbid musculoskeletal-neurovascular injuries","18 Years","65 Years",{"count":60,"type":20},52,"24 Weeks","OBSERVATIONAL","Considering the thumb's contribution to fine dexterity and precision grip, this study aims to evaluate fine manual dexterity alongside functional outcomes following isolated thumb tendon injuries, and to examine the relationship between postoperative functional improvement and changes in fine manual dexterity.",[29,65],"Tendon Injuries",[67,68,69,70],"functional status","fine dexterity","thumb","tendon injury","NOT_YET_RECRUITING","2026-02-04",{"date":74,"type":41},"2026-02-06",{"date":76,"type":20},"2026-02-26",{"date":78,"type":20},"2027-03-01",{"name":80,"class":48},"Pamukkale University",1,{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":92,"conditions":93,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":99,"leadSponsor":101,"locationsCount":81},"100596039","smartphone-addiction-on-the-biomechanical-properties-of-thumb-muscles-and-thumb-sensory-sensitivity-100596039","NCT07040267","Smartphone Addiction on the Biomechanical Properties of Thumb Muscles and Thumb Sensory Sensitivity","Investigation of the Effect of Smartphone Addiction on the Biomechanical Properties of Thumb Muscles and Thumb Sensory Sensitivity in University Students","Inclusion Criteria:\n\n* Aged 18-30 years\n* Currently enrolled university students\n* Regular smartphone users\n\nExclusion Criteria:\n\n* Presence of systemic, chronic, or neuromuscular disorders\n* History of upper limb surgery or trauma\n* Neurological or orthopedic conditions affecting upper extremities\n* Subcutaneous fat over target muscles \\>20 mm\n* Presence of wounds or burns on the measurement area","30 Years",{"count":91,"type":20},36,"This study will aim to assess the effects of smartphone addiction on thumb muscle biomechanics and sensory sensitivity among university students. The research will investigate whether excessive smartphone use leads to significant differences in muscle tone, stiffness, elasticity, and sensory discrimination capabilities.",[94,29],"Smartphone Addiction","2025-07-01",{"date":97,"type":41},"2025-07-02",{"date":95,"type":41},{"date":100,"type":20},"2026-07-01",{"name":102,"class":48},"Saglik Bilimleri Universitesi",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":109,"targetDuration":4,"studyType":21,"phases":111,"briefSummary":112,"conditions":113,"keywords":116,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":81},"100572338","the-impact-of-using-mobile-games-on-rehabilitation-outcomes-in-thumb-rehabilitation-100572338","NCT06731972","The Impact of Using Mobile Games on Rehabilitation Outcomes in Thumb Rehabilitation","Inclusion Criteria:\n\n* Patients aged 18-65\n* With sufficient communication skills\n* Experiencing pain and functional impairment in the thumb (e.g., thumb fractures, tendon injuries, nerve injuries, osteoarthritis, trigger thumb, carpal tunnel syndrome, ligament injuries, soft tissue damage, etc.),\n* who are willing to volunteer.\n\nExclusion Criteria:\n\n\\- Illiteracy, lack of a smartphone, or the presence of neurological, orthopedic, or rheumatological chronic diseases in the affected limb.",{"count":110,"type":20},38,[23],"Hand injuries and diseases are common reasons for hospital visits and lead to both functional and workforce losses, making them a persistent problem in treatment and rehabilitation approaches. Among the various functions of the hand, the thumb is of particular importance due to its large representation in the brain and its contribution to all gripping and holding functions. Loss of function in the thumb leads to a loss of at least 40% of hand skills. Therefore, restoring the thumb's original functionality is this study primary goal in rehabilitation. To achieve this goal, intensive rehabilitation is required, which cannot be fully accomplished through clinic sessions alone, as home exercises contribute significantly to this process. The low adherence of patients to home exercises has led researchers to explore various alternatives.\n\nThe aim of this study is to investigate the effect of mobile application games on rehabilitation outcomes in patients who have lost thumb function. For the pre- and post-treatment evaluations of the patients, the following assessment tools will be used: the Visual Analog Scale (VAS) for pain, the eight-shaped tape measure for edema, the Quick-DASH (Disabilities of the Arm, Shoulder, and Hand) scale for upper extremity functionality, a finger goniometer for joint range of motion, the DuruÖz Hand Index for measuring activities of daily living, and a home exercise adherence tracking form to evaluate adherence to home exercises.\n\nAs determined by this study power analysis, 38 patients with thumb injuries will be included in the study. These patients will be randomly assigned into two groups: the routine treatment group (19 patients) and the routine treatment plus mobile game group (19 patients). The routine treatment group will receive standard treatment at the Kırşehir Ahi Evran University Faculty of Physiotherapy and Rehabilitation Hand Clinic, including classical massage, stretching, functional exercises, electrical modalities, thermal agents, and home exercises. In the routine treatment plus mobile game group, in addition to the standard treatment, patients will engage in 20-30 minutes of mobile application games (e.g., Temple Run, Flappy Bird, Angry Birds) as part of their home exercise program.\n\nResearchers hypothesize that the group receiving mobile games in addition to the standard treatment will experience a better rehabilitation process in terms of thumb functionality, pain, and edema compared to the routine treatment group, and they will reach rehabilitation goals more quickly. Additionally, mobile games will increase motivation for home exercises and improve adherence. This study will be the first to examine the use of mobile games in thumb rehabilitation and their effect on adherence to home exercises. Researchers anticipate that the results of this study will inspire both clinicians and future research, reaching a wider audience through presentations and publications.",[29,114,115],"Rehabilitation Outcome","Mobile Phone Use",[35,117,118,119],"Rehabilitation","Games","Technology","2024-12-09",{"date":122,"type":41},"2024-12-13",{"date":124,"type":41},"2024-05-15",{"date":126,"type":20},"2025-02-01",{"name":128,"class":48},"Kirsehir Ahi Evran Universitesi"]