[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"thymectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:thymectomy":34},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,62,96,124,155],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":46,"overallStatus":49,"whyStopped":4,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":61},"100567703","stanford-program-to-accelerate-robotic-childrens-surgery-100567703",false,"NCT06671639","Stanford Program to Accelerate Robotic Children's Surgery","SPARCS","Inclusion Criteria:\n\n1. Subject is between 6 - 21 years of age (weighing at least 15 kilograms)\n2. Subject clinically diagnosed with a medical condition for which one of the study procedures is appropriate therapy and selected as the treatment of choice by the guardian and surgeon.\n3. Subject without previous treatment using a robotic surgery device\n4. Subject or their guardian is willing and able to provide written informed consent\n5. Subject or their guardian is willing and able to comply with the study protocol requirements\n\nExclusion Criteria:\n\n1. Subject with uncorrected coagulopathy\n2. Subject has clinical requirement for primary open operative procedure\n3. Subject is ASA 4 or 5 status\n4. Subject is contraindicated for general anesthesia or surgery\n5. Subject is mentally handicapped or has a psychological disorder or severe systemic illness that would preclude compliance with study requirements or ability to provide informed consent\n6. Subject is pregnant or suspected to be pregnant","ALL","6 Years","21 Years",{"count":20,"type":21},250,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to provide additional data to confirm safety and performance of the da Vinci Xi Surgical System in a human clinical setting. This pilot study is intended to provide an initial assessment to evaluate the feasibility, safety, and effectiveness for the utilization of the da Vinci Xi on pediatric and adolescent patients. This clinical trial will be conducted under the auspices of Stanford University's IRB approval.",[27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45],"Sleeve Gastrectomy","Cholecystectomy","Splenectomy","Hysterectomy","Endometriosis","Ureteral Re-implant","Cervical and Thoracic Tracheoplasty","Thymectomy","Lobectomy\u002FWedge Lung Resection","Lung Segmentectomy","Bronchoplasty","Endoscopic Laryngeal\u002FPharyngeal Suturing","Vocal Feminization","Laryngeal Cleft Repair","Endolaryngeal Adjacent Tissue Transfer","Pharyngoplasty","Ileocolonic Resections","Laryngoplasty","Proctectomy With Ileal Pouch-Anal Anastomosis",[47,48],"Robotic Surgery","Pediatric Robotic Surgery","RECRUITING","2026-04-24",{"date":52,"type":53},"2026-04-30","ACTUAL",{"date":55,"type":53},"2025-08-01",{"date":57,"type":21},"2028-02-28",{"name":59,"class":60},"Stanford University","OTHER",1,{"id":63,"slug":64,"hasResults":11,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":70,"enrollmentInfo":71,"targetDuration":4,"studyType":22,"phases":73,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":49,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":95},"100594470","impact-of-thymectomy-on-immunity-in-infants-after-cardiac-surgery-100594470","NCT07019857","Impact of Thymectomy on Immunity in Infants After Cardiac Surgery","Impact of Thymectomy on Immune Response in Infants 12 Months After Cardiac Surgery: a Single-centre Prospective Study","THYMIC","Inclusion Criteria:\n\n* \\- Children aged between 0 and 6 months;\n* Born at a gestational age \\> 37 weeks' gestation;\n* With an indication for cardiac surgery under CEC at Nantes University Hospital;\n* Cardiopediatric follow-up planned at Nantes University Hospital;\n* Written agreement signed by legal guardians to participate in the study.\n\nFor the control groups:\n\n* Control group A (cardiac surgery without thymectomy):\n\n  * Children aged between 0 and 6 months of age;\n  * Born at a gestational age \\> 37 SA;\n  * Indicated for thoracotomy cardiac surgery at Nantes University Hospital;\n  * Cardiopediatric follow-up planned at Nantes University Hospital;\n  * Written agreement signed by legal guardians to participate in the study.\n* Control group B (non-cardiac surgery)\n\n  * Children aged between 0 and 6 months;\n  * Born at a gestational age \\> 37 SA;\n  * Indicated for non-cardiac surgery (ENT or visceral surgery at Nantes University Hospital);\n  * Planned follow-up surgery at Nantes University Hospital;\n  * Written agreement signed by legal guardians to participate in the study.\n\nExclusion Criteria :\n\n* Gestational age \\\u003C 37 SA;\n* With a history of cardiac surgery under ECG;\n* And\u002For with heart disease requiring further surgery within 12 months of the 1st surgery (e.g. pulmonary cerclage, systemic pulmonary anastomosis).\n* And\u002For a history of partial or complete thymectomy;\n* Receiving long-term immunosuppressive treatment;\n* Post-operative follow-up planned in a hospital other than Nantes University Hospital, or moving house planned during the follow-up period;\n* parental refusal.\n\nExclusion Criteria:\n\n* \\- Gestational age \\\u003C 37 SA;\n* With a history of cardiac surgery under ECG;\n* And\u002For with heart disease requiring further surgery within 12 months of the 1st surgery (e.g. pulmonary cerclage, systemic pulmonary anastomosis).\n* And\u002For a history of partial or complete thymectomy;\n* Receiving long-term immunosuppressive treatment;\n* Post-operative follow-up planned in a hospital other than Nantes University Hospital, or moving house planned during the follow-up period;\n* parental refusal.","6 Months",{"count":72,"type":21},70,[24],"Heart surgery in infants typically involves complete removal of the thymus gland to improve access to the heart. However, the thymus plays a key role in developing the immune system in early childhood, especially in the production and maturation of T lymphocytes, which help the body defend itself against infections.\n\nThe THYMIC study tests the hypothesis that partial removal of the thymus (partial thymectomy) during heart surgery may better preserve the child's immune function compared to total removal (complete thymectomy). The goal is to determine whether this conservative surgical approach could reduce the risk of immune system impairment and infections in the months following surgery.\n\nThis is a prospective, interventional, single-center study conducted at CHU de Nantes, involving 3 groups of infants:\n\n* One group undergoing heart surgery with complete thymectomy;\n* One group undergoing heart surgery with partial thymectomy;\n* One control group undergoing heart or non-heart surgery without thymus removal. All infants enrolled will have two blood tests: one taken during their surgery and one taken one year later. These blood tests will quantify immune cells (T, B, NK cells), levels of antibodies, and vaccine responses. Parents will also be asked to fill out a questionnaire to record any infections their child experiences during the year after surgery.\n\nBy comparing the immune responses and infection rates among the groups, the researchers hope to better understand the long-term effects of thymectomy in infants. The results could support future recommendations to preserve part of the thymus when possible during heart surgery.\n\nParticipation in the study does not change the medical or surgical care of the child. The decision to perform a partial or complete thymectomy is made by the surgeon based on the child's anatomy. The additional blood samples are small in volume and follow current safety regulations.",[76,34,77],"Congenital Heart Defects","Immunological Deficiency Syndrome",[34,79,80,81,82,83,84,85],"Cardiac Surgery","Infant","Immunity","Lymphocytes","TRECs","Vaccination","Infection","2026-04-13",{"date":88,"type":53},"2026-04-16",{"date":90,"type":53},"2025-07-25",{"date":92,"type":21},"2027-12-01",{"name":94,"class":60},"Nantes University Hospital",2,{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":16,"minAge":103,"maxAge":4,"enrollmentInfo":104,"targetDuration":4,"studyType":22,"phases":106,"briefSummary":107,"conditions":108,"keywords":110,"overallStatus":114,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":61},"100614054","comparing-the-therapeutic-efficacy-of-extended-isthmusectomy-versus-total-thyroidectomy-for-isthmus-tumors-of-the-thyroid-100614054","NCT07274605","Comparing the Therapeutic Efficacy of Extended Isthmusectomy Versus Total Thyroidectomy for Isthmus Tumors of the Thyroid","Comparing the Therapeutic Efficacy of Extended Isthmusectomy Versus Total Thyroidectomy for Isthmus Tumors of the Thyroid: A Prospective, Multicenter, Open-Label, Randomized Controlled Trial.","Inclusion Criteria:\n\n\\- Age 18 years or older.\n\nDiagnosis of low-risk differentiated thyroid cancer (papillary, follicular, or Hürthle cell carcinoma).\n\nUnifocal tumor located in the thyroid isthmus, cT1b\n\nNo evidence of extrathyroidal extension, assessed by preoperative ultrasound.\n\nExclusion Criteria:\n\n\\- Aggressive pathological subtypes (e.g., tall cell, clear cell, columnar cell, or diffuse sclerosing variants of papillary thyroid carcinoma, as well as poorly differentiated types).\n\ncN1b.\n\nM1\n\nCombined with other suspicious thyroid nodules within the lobes.","18 Years",{"count":105,"type":21},520,[24],"Prospective randomized open phase III non-inferiority trial in cT1bN0N1aM0 isthmus tumors of the thyroid comparing: extended Isthmusectomy (Isthmusectomy + Central Neck Dissection)(experimental group) versus total thyroidectomy + Central Neck Dissection (reference group).",[34,109],"Thyroid Cancer",[111,112,113],"thyroid cancer","isthmus","surgery","NOT_YET_RECRUITING","2025-12-09",{"date":117,"type":53},"2025-12-10",{"date":119,"type":21},"2025-12-19",{"date":121,"type":21},"2032-12-01",{"name":123,"class":60},"Second Affiliated Hospital, School of Medicine, Zhejiang University",{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":130,"eligibilityCriteria":131,"healthyVolunteers":11,"sex":16,"minAge":103,"maxAge":4,"enrollmentInfo":132,"targetDuration":4,"studyType":22,"phases":134,"briefSummary":135,"conditions":136,"keywords":142,"overallStatus":49,"whyStopped":4,"lastUpdateSubmitDate":146,"lastUpdatePostDateStruct":147,"startDateStruct":149,"completionDateStruct":151,"leadSponsor":153,"locationsCount":61},"100557999","serratus-posterior-superior-intercostal-plane-block-in-robotic-assisted-thymectomy-100557999","NCT06545409","Serratus Posterior Superior Intercostal Plane Block in Robotic-Assisted Thymectomy","Use of Serratus Posterior Superior Intercostal Plane Block in Robotic-Assisted Thoracoscopic Surgery for Thymectomy: A Randomized Controlled Trial","SPRATS","Inclusion Criteria:\n\n* Patients affected by thymoma, thymic hyperplasia, or thymic pathologies (cysts, teratomas) who have given informed consent to the study.\n\nExclusion Criteria:\n\n* Patients who refuse to participate in the study by not signing the informed consent;\n* Patients with myasthenia gravis, severe obesity (BMI \\> 35), history of OSAS with or without CPAP;\n* Patients belonging to ASA classes \\> 3, according to the system developed by the American Society of Anesthesiologists;\n* Patients unable to understand the functioning of the NPR Scale or the PCA device that will be used for postoperative analgesia;\n* Patients with allergies to analgesic and\u002For anesthetic drugs;\n* Patients on anticoagulant therapy;\n* Patients with a history of chronic pain;\n* Patients with an infection at the site where SPSIPB will be performed;\n* Patients who have had previous thoracic surgery and\u002For thoracic trauma with rib fractures on the side of the surgery;\n* Patients with chest deformities and\u002For neuromuscular diseases that interfere with normal ventilatory function.\n\nAdditionally, patients whose surgery is intraoperatively converted to sternotomy thymectomy will be excluded post-hoc from the study.",{"count":133,"type":21},28,[24],"This study aims to assess the effectiveness of the Serratus Posterior Superior Intercostal Plane Block (SPSIP Block) for postoperative pain control, reducing opioid analgesic consumption, minimizing postoperative respiratory complications, and enhancing patient satisfaction (measured using the QoR-15 index) in patients undergoing robotic thymectomy, compared to patients who do not receive the block.",[137,34,138,139,140,141],"RATS Surgery","Locoregional Anesthesia","Postoperative Pain Management","Serratus Posterior Superior Intercostal Plane Block","Robotic-Assisted Thoracoscopic Surgery",[143,144,145],"SPSIP","RATS Thymectomy","Thymoma","2025-03-20",{"date":148,"type":53},"2025-03-25",{"date":150,"type":53},"2025-03-01",{"date":152,"type":21},"2026-09-15",{"name":154,"class":60},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS",{"id":156,"slug":157,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":4,"eligibilityCriteria":161,"healthyVolunteers":11,"sex":16,"minAge":162,"maxAge":163,"enrollmentInfo":164,"targetDuration":4,"studyType":22,"phases":166,"briefSummary":167,"conditions":168,"keywords":169,"overallStatus":49,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":61},"100379660","video-assisted-thoracoscopic-thymectomy-versus-subxiphoid-procedure-100379660","NCT04223466","Video-assisted Thoracoscopic Thymectomy Versus Subxiphoid Procedure","Video-assisted Thoracoscopic Thymectomy Versus Subxiphoid Thymectomy: Short- Term and Long- Term Results","Inclusion Criteria:\n\n1. Thymoma with or without myasthenia gravis；\n2. Generalized myasthenia gravis not sensitive to conservative medicine treatment;\n3. Good cardiopulmonary function.\n\nExclusion Criteria:\n\n1. Cardiopulmonary function can't bear surgery;\n2. Generalized myasthenia gravis with MuSK(+).","20 Years","80 Years",{"count":165,"type":21},100,[24],"Surgerys used in thymectomy for myasthenia gravis and anterior mediastinal tumours have become much less invasive in recent years. In our study, the surgical technique which resected the thymus below the xiphoid process and the technique which was regarded as conventional video- assisted thoracoscopic surgery (VATS) thymectomy was compared.",[34],[170,171],"Video-assisted thoracoscopic surgery","Subxiphoid approach","2022-11-14",{"date":174,"type":53},"2022-11-16",{"date":176,"type":53},"2020-01-07",{"date":178,"type":21},"2027-12-31",{"name":180,"class":60},"The Second Hospital of Shandong University"]