[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"thyroid-dysfunction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:thyroid-dysfunction":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,49,76,99,130,150],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100625855","postoperative-hypocalcemia-after-thyroidectomy-100625855",false,"NCT07428057","Postoperative Hypocalcemia After Thyroidectomy","A Ten-Year Cohort Study of Clinical and Surgical Predictors for Hypocalcemia Post-Thyroidectomy","Inclusion Criteria:\n\n* Adult patients aged 18 years or older at time of surgery\n* Underwent thyroidectomy at Minia University Hospital\n* Availability of medical records with complete surgical and postoperative data\n* Documented serum calcium levels measured postoperatively\n* Minimum follow-up of 6 months postoperatively or documented outcome status\n\nExclusion Criteria:\n\n* Age less than 18 years at time of surgery\n* Preoperative hypocalcemia (serum calcium \\\u003C8.0 mg\u002FdL or ionized calcium \\\u003C1.0 mmol\u002FL)\n* Pre-existing parathyroid disorders (primary hyperparathyroidism, hypoparathyroidism, secondary or tertiary hyperparathyroidism)\n* Chronic kidney disease Stage 3 or higher (estimated glomerular filtration rate \\\u003C60 mL\u002Fmin\u002F1.73m²)\n* Malabsorption syndromes affecting calcium metabolism (celiac disease, inflammatory bowel disease,short bowel syndrome)\n* Concurrent planned parathyroidectomy\n* History of neck irradiation\n* Chronic use of medications significantly affecting calcium metabolism (bisphosphonates, denosumab,cinacalcet, chronic corticosteroids)\n* Incomplete medical records lacking essential data including surgical details, postoperative calcium levels,or follow-up data\n* Patients lost to follow-up before 6-month endpoint without documented outcome status","ALL","18 Years","75 Years",{"count":20,"type":21},600,"ESTIMATED","OBSERVATIONAL","This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024). Postthyroidectomy hypocalcemia is one of the most common complications of thyroid surgery, affecting 20-50% of patients. The study aims to identify demographic, clinical, laboratory, and surgical factors associated with the development of both transient and permanent hypocalcemia. Results will inform risk stratification, patient counseling, and perioperative management strategies.",[25,26,27,28,29],"Thyroid Nodule","Thyroid Dysfunction","Hypocalcemia","Thyroid Cancer","Postoperative Complications",[31,32,33,34,35],"Thyroidectomy","Postoperative hypocalcemia","Hypoparathyroidism","Parathyroid gland injury","Total thyroidectomy","RECRUITING","2026-06-27",{"date":39,"type":40},"2026-06-30","ACTUAL",{"date":42,"type":40},"2026-03-04",{"date":44,"type":21},"2026-08-01",{"name":46,"class":47},"Minia University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100605034","evaluation-of-thyroid-function-lipid-profile-and-uric-acid-levels-in-hemodialysis-patients-100605034","NCT07157267","Evaluation of Thyroid Function, Lipid Profile, and Uric Acid Levels in Hemodialysis Patients","Evaluation of Thyroid Function, Lipid Profile, and Uric Acid Levels in Patients Undergoing Hemodialysis Prevalence in Assiut University Hospital","Inclusion Criteria:\n\n* Adults ≥18 years\n* On regular hemodialysis for ≥3 months\n\nExclusion Criteria:\n\n* On lipid-lowering or uric acid-lowering medications\n* Acute infections or hospitalizations in the past month",{"count":57,"type":21},100,"This observational study evaluates the prevalence and relationships of thyroid dysfunction, lipid abnormalities, and elevated uric acid levels in adult patients undergoing maintenance hemodialysis at Assiut University Hospital.",[26,60,61],"Hemodialysis","Elevated Uric Acid",[63,64,65],"hemodialysis","elevated uric acid","Thyroid Function Status","NOT_YET_RECRUITING","2025-08-28",{"date":69,"type":40},"2025-09-05",{"date":71,"type":21},"2026-07-01",{"date":73,"type":21},"2027-12-30",{"name":75,"class":47},"Assiut University",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":4},"100600626","relationship-between-thyroid-dysfunction-and-diabetes-100600626","NCT07099937","Relationship Between Thyroid Dysfunction and Diabetes","Metabolic Syndrome and Thyroid Dysfunction in Type 2 Diabetes In Upper Egypt","Inclusion Criteria:\n\n* Patients diagnosed with type 2 diabetes mellitus in upper egypt.\n* Age above 18 years.\n* Patients who gave informed consent to participate.\n\nExclusion Criteria:\n\n* Patients with type 1 diabetes mellitus.\n* Age below 18 years.\n* Patients with known autoimmune thyroid diseases, pregnancy, or acute illness at the time of assessment.","80 Years",{"count":85,"type":21},120,"Evaluate the expression of glycemic parameters, lipid profile, and thyroid hormones in patients with type 2 diabetes mellitus in upper egypt.",[88,26,89,90],"Type 2 Diabetes Mellitus (T2DM)","Metabolic Syndrome","Upper Egypt Patients","2025-07-30",{"date":93,"type":40},"2025-08-01",{"date":95,"type":21},"2025-09-01",{"date":97,"type":21},"2026-10",{"name":75,"class":47},{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":106,"maxAge":107,"enrollmentInfo":108,"targetDuration":4,"studyType":110,"phases":111,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":4},"100591410","wearable-devices-assist-in-the-detection-screening-and-management-of-major-diseases-in-middle-aged-and-elderly-populations-100591410","NCT06980064","Wearable Devices Assist in the Detection, Screening, and Management of Major Diseases in Middle-aged and Elderly Populations","Wearable Devices Assist in the Detection, Screening, and Management of Major Diseases in Middle-aged and Elderly Populations: a Multicenter Randomized Controlled Trial","The inclusion criteria are as follows:\n\n1. Aged more than equal to 40 years, less than 69 years.\n2. Having at least one of the following conditions (with one risk factor for cardiovascular and cerebrovascular diseases):\n\n   ① Male ≥ 55 years old, female ≥ 65 years old; ② Smokers or those who quit smoking within the past 3 months prior to the visit; ③ Diabetes (type 1 or 2); ④ Hypertension (systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg) or currently taking antihypertensive medication; ⑤ Dyslipidemia: total cholesterol ≥ 5.18mmol\u002FL, triglycerides ≥ 1.70mmol\u002FL, high-density lipoprotein\\\u003C1.04mmol or low-density lipoprotein ≥ 3.37mmol\u002FL; ⑥ hsCRP\\>3.0 mg\u002FL; ⑦ 10-year ASCVD risk of 20% or more (calculated according to the formula designed in the PREVENT study)\n3. Agree to receive coronary CTA if suspected to have coronary artery stenosis.\n4. Voluntarily joined and signed the informed consent.\n\nThe exclusion criteria:\n\n1. Previously diagnosed with CAD or considered moderate to severe coronary stenosis (CAD-RADS grade 3 or above: stenosis degree of 50% or above) through coronary CTA or coronary angiography examination.\n2. Pregnant women or women planning to become pregnant within the next year.\n3. During the onset of the disease and needs in-hospital treatment.\n4. Tattoos or other substances that affect optical signals on the wrist.\n5. Severe arrhythmia patients, including third degree atrioventricular block, ventricular escape rhythm, severe sinus bradycardia, sick sinus syndrome, supraventricular tachycardia, ventricular tachycardia, atrial fibrillation, atrial flutter, ventricular fibrillation, ventricular flutter.\n6. Physical disability, blindness, and deafness.\n7. Allergic history of contrast agent containing iodine.","40 Years","69 Years",{"count":109,"type":21},800,"INTERVENTIONAL",[112],"NA","The goal of this randomized controlled trial is to evaluate the effectiveness of wearable devices (Huawei smartwatches) in aiding the detection, and screening of major diseases (e.g., coronary artery disease, hypertension) in middle-aged and elderly populations aged 40-69 years with cardiovascular risk factors (e.g., smoking, diabetes, hypertension, dyslipidemia). The main questions it aims to answer are:\n\nDoes AI-assisted diagnosis using wearable device data improve the detection rate of coronary artery stenosis (CAD-RADS ≥3) compared to standard physician assessment without AI assistance?\n\nDoes the intervention reduce the incidence of coronary artery disease-related events (e.g., angina, myocardial infarction) within one year?\n\nResearchers will compare the intervention group (AI model-assisted diagnosis based on Huawei smartwatch data) with the control group (standard assessment) to determine if the AI-aided smartwatch approach enhances diagnostic accuracy and clinical outcomes.\n\nParticipants will:\n\n（Intervention group）Wear a Huawei smartwatch for 24 hours to collect physiological data (e.g., PPG signals, heart rate, motion).\n\nUndergo baseline assessments, including medical history review, physical exams, and laboratory tests.\n\nReceive a preliminary diagnosis from a general practitioner.\n\nComplete a follow-up evaluation after one year to track cardiovascular events and other disease outcomes.\n\nUndergo coronary CTA if suspected of coronary stenosis.",[115,116,117,118,119,120,26],"Coronary Stenosis","Cerebral Arterial Diseases","Hypertension","Parkinson Disease","Heart Failure","Peripheral Arterial Occlusive Disease","2025-05-16",{"date":123,"type":40},"2025-05-20",{"date":125,"type":21},"2025-06-01",{"date":127,"type":21},"2026-12-31",{"name":129,"class":47},"Tongji Hospital",{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":134,"acronym":4,"eligibilityCriteria":135,"healthyVolunteers":136,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":137,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":139,"conditions":140,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":146,"leadSponsor":148,"locationsCount":48},"100572904","thyroid-dysfunction-and-its-association-with-metabolic-dysfunction-associated-fatty-liver-disease-100572904","NCT06739330","Thyroid Dysfunction and Its Association With Metabolic Dysfunction-Associated Fatty Liver Disease","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Both sexes.\n* Patients with metabolic dysfunction-associated fatty liver disease (MAFLD).\n\nExclusion Criteria:\n\n* History of thyroid disease or treatment (e.g., thyroid nodules, thyroid cancer, hypothyroidism, and hyperthyroidism).\n* Patients with alcoholic liver disease take more than 40g of alcohol (or four units) per day.\n* Viral hepatitis.\n* Pregnant women.",true,{"count":138,"type":21},150,"This study aims to evaluate the prevalence of thyroid dysfunction and its association with metabolic dysfunction-associated fatty liver disease.",[26,141],"Metabolic Dysfunction-Associated Fatty Liver Disease","2024-12-19",{"date":144,"type":40},"2024-12-20",{"date":142,"type":40},{"date":147,"type":21},"2025-05-01",{"name":149,"class":47},"Tanta University",{"id":151,"slug":152,"hasResults":11,"nctId":153,"briefTitle":154,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":156,"enrollmentInfo":157,"targetDuration":159,"studyType":22,"phases":4,"briefSummary":160,"conditions":161,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":4},"100560581","prevalence-and-prognostic-effects-of-thyroid-abnormalities-in-patients-with-acute-coronary-syndrome-100560581","NCT06579014","Prevalence and Prognostic Effects of Thyroid Abnormalities in Patients With Acute Coronary Syndrome.","Inclusion Criteria:\n\n* Patients with ACS: (STEMI\\_NSTEMI)\n\nExclusion Criteria:\n\n* 1-patients with cardiogenic shock. 2- patients with other endocrinal diseases. 3- patients on dialysis. 4-patients with Acute malignancy. 5-patient with thyroid diseases on treatment. 6- patients with liver diseases. 7-patients with Any autoimmune diseases","90 Years",{"count":158,"type":21},129,"6 Months","The goal of this observational study is knowledge of Prevalence of throid abnormalities in patients with acute coronary syndrome And prognostic effects of thyroid abnormalities in patients with acute coronary syndrome as early detection and management of thyroid abnormalities can improve clinical outcomes.",[26],"2024-09-05",{"date":164,"type":40},"2024-09-19",{"date":166,"type":21},"2024-09-01",{"date":168,"type":21},"2026-11",{"name":75,"class":47}]