[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"thyroid-gland\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:thyroid-gland":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100581037","impact-of-thyroid-treatment-on-ovarian-function-and-pregnancy-outcomes-in-women-with-differentiated-thyroid-cancer-100581037",false,"NCT06845098","Impact of Thyroid Treatment on Ovarian Function and Pregnancy Outcomes in Women with Differentiated Thyroid Cancer","Impact of Thyroid Treatment on Ovarian Function and Pregnancy Outcomes in Women with Differentiated Thyroid Cancer: a Prospective Cohort Study","Inclusion criteria:\n\n1. Age 20-45 years old;\n2. Premenopausal women whose thyroid B-ultrasound + surgical pathology is clearly differentiated thyroid cancer (papillar thyroid cancer or follicular thyroid cancer);\n3. TNM stage is in stage I (T1-3, N0 or N1, M0);\n4. Treatment of thyroid tumor resection: unilateral lobe of the thyroid + isthmus resection, total thyroidectomy, total thyroidectomy + RAIT.\n\nExclusion criteria:\n\n1. Patients with malignant tumors in other parts or low undifferentiated thyroid cancer;\n2. Patients with abnormal liver and kidney function;\n3. TNM stage II and above;\n4. History of ovarian surgery, hysterectomy, pelvic surgery or radiation therapy;\n5. Pregnancy;\n6. Have the following uterine abnormalities, such as uterine malformation (single-horned uterus, double uterus); untreated mediastinal uterus, submucosal uterine fibroids, multiple endometrial polyps, or severe uterine adhesion.\n7. Patients diagnosed with polycystic ovary syndrome by the Rotterdam standard;\n8. Patients with ovarian failure;\n9. Patients have infectious factors, immune diseases and metabolic diseases that may affect pregnancy outcomes;\n10. Pregnancy contraindications or diseases that have a clear impact on pregnancy.","FEMALE","20 Years","45 Years",{"count":20,"type":21},300,"ESTIMATED","INTERVENTIONAL",[24],"NA","This project aims to study the effects of different types of thyroid surgery and RAIT on ovarian function and pregnancy outcomes of DTC women of childbearing age, analyze possible risk factors, and assess whether potential risk factors such as age, thyroid stimulating hormone (TSH) levels and positive thyroid antibodies are related to ovarian hypofunction and adverse pregnancy outcomes.",[27],"Thyroid Gland","NOT_YET_RECRUITING","2025-02-19",{"date":31,"type":32},"2025-02-25","ACTUAL",{"date":34,"type":21},"2025-02-20",{"date":36,"type":21},"2028-12-31",{"name":38,"class":39},"Zhejiang Provincial People's Hospital","OTHER"]