[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"thyroid-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:thyroid-surgery":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,42,67,99,128,158,185,206],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100638700","effects-of-two-anesthesa-technques-on-inflammatory-response-and-amno-acd-metabolsm-n-thyrod-surgery-100638700",false,"NCT07592832","EFFECTS OF TWO ANESTHESİA TECHNİQUES ON INFLAMMATORY RESPONSE AND AMİNO ACİD METABOLİSM İN THYROİD SURGERY","THE EFFECT OF TWO DİFFERENT ANESTHESİA APPROACHES ON PERİOPERATİVE INFLAMMATORY RESPONSE AND AMİNO ACİD METABOLİSM İN THYROİD SURGERY","Inclusion Criteria:\n\n* This includes patients aged 18-70 years\n* classified as ASA I-III\n* who have undergone elective thyroidectomy.\n\nExclusion Criteria:\n\n* Patients who did not wish to participate in the study voluntarily\n* patients for whom superficial cervical block was contraindicated\n* pregnant and breastfeeding women\n* patients in ASA IV-V groups were excluded from the study.","ALL","18 Years","70 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","The main aim of this study is to compare the effects of two different anesthesia methods-(1) general anesthesia alone and (2) combination of general anesthesia with cervical plexus block-on postoperative inflammatory process and amino acid metabolism in patients undergoing thyroidectomy.",[27,28,29],"General Anesthesia","Cervical Plexus Block","Thyroid Surgery","NOT_YET_RECRUITING","2026-05-15",{"date":33,"type":34},"2026-05-18","ACTUAL",{"date":36,"type":21},"2026-07-30",{"date":38,"type":21},"2027-02-20",{"name":40,"class":41},"Harran University","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":66},"100627854","nurse-led-emotional-freedom-technique-for-preoperative-anxiety-and-fear-in-thyroid-surgery-100627854","NCT07454044","Nurse-Led Emotional Freedom Technique for Preoperative Anxiety and Fear in Thyroid Surgery","The Effect of Emotional Freedom Techniques on Preoperative Anxiety and Fear in Patients Undergoing Thyroid Surgery","EFT","Inclusion Criteria:\n\n* Patients scheduled for thyroid surgery\n* Aged 18 years and older\n* Able to speak and understand Turkish\n* Literate (able to read and write)\n* No visual, hearing, or mental impairment\n* Able to communicate effectively\n* Preoperative anxiety and fear level of 3 or higher according to the Subjective Units of Distress (SUD) scale\n\nExclusion Criteria:\n\n* Presence of a neurological disorder\n* Diagnosed psychiatric disorder and current use of medication for this condition\n* Previous training related to coping with anxiety or fear\n* Previous participation in an energy therapy course\n* Presence of infection, wound, or scar at the tapping (touch) sites",{"count":51,"type":21},70,[24],"Emotional Freedom Technique (EFT) is a non-invasive, low-cost complementary intervention that has been used in various clinical settings to reduce anxiety and psychological distress. Although previous studies have suggested the potential benefits of EFT in general anxiety and postoperative psychological outcomes, evidence regarding its effectiveness in patients undergoing thyroid surgery is limited. Thyroid surgery is associated with unique sources of preoperative anxiety and fear due to potential complications related to voice, swallowing, and hormonal balance.\n\nThis randomized controlled study aims to evaluate the effect of Emotional Freedom Technique on preoperative anxiety and fear in patients undergoing thyroid surgery. Eligible patients will be randomly assigned to an intervention group receiving EFT in addition to standard preoperative nursing care or to a control group receiving standard preoperative nursing care alone. EFT will be administered by trained nurses following a standardized protocol during the preoperative period. Anxiety and fear levels will be assessed using validated measurement tools before and after the intervention. The findings of this study are expected to contribute to evidence-based nursing practices and to support the integration of complementary interventions into perioperative nursing care.",[55,56,29],"Preoperative Anxiety","Fear and Anxiety","2026-03-05",{"date":59,"type":34},"2026-03-06",{"date":61,"type":21},"2026-02-09",{"date":63,"type":21},"2026-07",{"name":65,"class":41},"Saglik Bilimleri Universitesi",1,{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":22,"phases":77,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":66},"100574950","pteye-vs-surgeons-eyes-in-intraoperative-identification-and-functional-preservation-of-parathyroid-glands-during-thyroid-surgery-a-parallel-randomized-controlled-clinical-trial-100574950","NCT06765941","PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial.","Clinical Validation of Probe-based Parathyroid Autofluorescence Detection System PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial.","PTSURGEYE","Inclusion Criteria:\n\n* a patient with thyroid disease qualified for first-time total thyroidectomy.\n\nExclusion Criteria:\n\n* history of thyroid or parathyroid surgery,\n* planned simultaneous thyroid and parathyroid surgery,\n* renal failure,\n* pregnancy,\n* lactation,\n* allergy to contrast agents and\u002For iodine,\n* inability of the patient to understand the study protocol,\n* inability to participate in the planned postoperative follow-up,\n* age below 18 years.",{"count":76,"type":21},154,[24],"The goal of this randomized clinical trial is to learn if there are any added benefits of using near-infrared autofluorescence (NIRAF) probe-based imaging system (the PTeye) for intraoperative identification of parathyroid glands (PGs) during thyroid surgery in comparison to visual identification of PGs by the surgeon's naked eyes without PTeye.\n\nThe main questions it aims to answer are:\n\n* Is number of PGs identified intraoperatively and preserved in situ larger in thyroid operations with PTeye versus surgeon's naked eyes without PTeye?\n* Is number of patients with undetectable or low parathormone serum level on postoperative day 1 fewer in thyroid operations with PTeye versus surgeon's naked eyes without PTeye?\n* Is number of patients requiring substitution therapy with calcium and vitamin D analogue fewer after thyroid operations with PTeye versus surgeon's naked eyes without PTeye in a short-term (\\\u003C 6 weeks) and\u002For in a long-term (at 6 months) follow-up?\n* Is numer of inadvertenly removed and reimplanted PGs fewer in thyroid operations with PTeye versus surgeon's naked eyes without PTeye?\n* Is number of frozen sections fewer in thyroid operations with PTeye versus surgeon's naked eyes without PTeye?\n* Is number of PGs identified by pathologist in the surgical specimen fewer in in thyroid operations with PTeye versus surgeon's naked eyes without PTeye?\n* Is number of patients with symptomatic hypoparathyroidism within 30 days of the operation fewer in thyroid operations with PTeye versus surgeon's naked eyes without PTeye? The hypothesis explored in this study is that use of PTeye in comparison to the surgeon's naked eyes may be beneficial for intraoperative identification and preservation of PGs in thyroid surgery leading to reduced risk of postoperative hypoparathyroidism.\n\nA prospective, randomized study with 2 arms: use of PTeye vs. visual identification of PGs without PTeye (n=77 patients, each).\n\nThe primary outcome measure is number of intraoperatively identified PGs with use of PTeye vs without it.",[29,80,81],"Parathyroid Dysfunction","Hypoparathyroidism Post-surgical",[83,84,85,86,87,88],"thyroid surgery","postoperative hypoparathyroidism","near-infrared autofluorescence","PTeye","probe-based parathyroid detection","visual identification","RECRUITING","2025-08-25",{"date":92,"type":34},"2025-09-02",{"date":94,"type":34},"2025-08-23",{"date":96,"type":21},"2026-06-30",{"name":98,"class":41},"Marcin Barczynski",{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":106,"targetDuration":4,"studyType":22,"phases":108,"briefSummary":109,"conditions":110,"keywords":113,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":4},"100587350","use-of-the-pteye-device-to-reduce-inadvertent-parathyroidectomy-during-thyroid-surgery-100587350","NCT06927245","Use of the PTEye Device to Reduce Inadvertent Parathyroidectomy During Thyroid Surgery","Use of Intraoperative Autofluorescence Imaging to Reduce the Incidence of Inadvertent Parathyroidectomy During Thyroid Surgery","Inclusion Criteria:\n\n* Patients undergoing either a total thyroidectomy or a thyroid lobectomy\n* Patients must be 18 years old or older\n* Patient needs to be operated on by a study approved surgeon\n\nExclusion Criteria:\n\n* Under 18 years old\n* Receiving a planned parathyroidectomy, Cistrunk procedure, repeat neck surgery, or neck dissection\n* Receiving surgery from a non-approved surgeon\n* Pregnant at time of procedure",{"count":107,"type":21},25,[24],"Inadvertent Parathyroidectomy (IP) during thyroid surgery may lead to transient or permanent hypoparathyroidism and hypocalcemia, which represents significant morbidity. Patients that suffer from IP and its clinical consequences often require longer duration of hospitalization and additional inpatient treatment and prescription medications. ProMedica performs a large number of endocrine procedures, so the use of novel technology to aid in the intra operative identification of parathyroid glands may ultimately offer decreased morbidity to patients.\n\nThe goal of this study is to find out if using the PTEye device (a device that uses infrared light to find the Parathyroid gland) lowers the amount of times a surgeon accidentally takes out the Parathyroid gland while trying to take out the Thyroid gland in surgery.",[29,111,112],"Inadvertent Parathyroidectomy","Enlarged Thyroid",[114,115,116,117,111,118],"PTEye","Total Thyroidectomy","Thyroid Lobectomy","Intraoperative Autofluorescence Imaging","Inadvertent Parathyroid Removal","2025-08-05",{"date":121,"type":34},"2025-08-11",{"date":123,"type":21},"2025-09-01",{"date":125,"type":21},"2025-12-31",{"name":127,"class":41},"ProMedica Health System",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":135,"targetDuration":4,"studyType":137,"phases":4,"briefSummary":138,"conditions":139,"keywords":140,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":149,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":157},"100593738","quantitative-intra-operative-assessment-of-parathyroid-perfusion-using-indocyanine-green-icg-fluorescence-imaging-100593738","NCT07010341","Quantitative Intra-operative Assessment of Parathyroid Perfusion Using Indocyanine Green (ICG) Fluorescence Imaging","Quantitative Intra-operative Assessment of Parathyroid Perfusion Using Indocyanine Green (ICG) Fluorescence Imaging: A Prospective Observational Study","Inclusion Criteria:\n\n* Scheduled for unilateral thyroid lobectomy plus central (VI-level) lymph-node dissection.\n* Intra-operative findings consistent with:\n* Complete identification and in-situ preservation of the ipsilateral superior parathyroid gland;\n* Complete identification and autotransplantation of the ipsilateral inferior parathyroid gland.\n* Serum 25-hydroxy-vitamin D ≥ 30 ng\u002FmL at baseline; patients below this level may be enrolled after standardized vitamin-D and calcium supplementation with re-test confirming ≥ 30 ng\u002FmL.\n* Surgery and all postoperative follow-up performed at the study center.\n* Able and willing to provide written informed consent.\n\nExclusion Criteria:\n\n* Prior surgery on the thyroid or parathyroid glands.\n* Severe hepatic or renal impairment, or other serious metabolic bone disease.\n* Pregnancy or lactation.\n* Known hypersensitivity to indocyanine green or iodine-containing compounds.\n* Inability or unwillingness to comply with postoperative visits and blood testing.",{"count":136,"type":21},210,"OBSERVATIONAL","This single-center, prospective, three-phase observational cohort quantifies the relationship between indocyanine green (ICG) fluorescence and early parathyroid function. Adult patients scheduled for unilateral thyroid lobectomy with autotransplantation of the ipsilateral inferior parathyroid gland are enrolled. After intravenous ICG 25 µg\u002Fkg, peak fluorescence of the superior parathyroid gland and the common carotid artery (CCA) is recorded at 60-120 seconds to calculate the ratio R = PTG\u002FCCA. Serum parathyroid hormone (PTH) is measured 30 minutes post-operatively. A derivation cohort (\\~120 patients) generates R-based thresholds for in-situ preservation versus autotransplantation, which are prospectively validated in an independent cohort (60 patients) together with decision-curve analysis of clinical net benefit.",[29],[141,142,143,144,145,146,147],"Thyroid surgery","Indocyanine Green","Near-Infrared Fluorescence","Parathyroid Perfusion","Perfusion Threshold","Hypocalcemia","Perfusion Ratio","2025-07-12",{"date":150,"type":34},"2025-07-15",{"date":152,"type":34},"2025-05-01",{"date":154,"type":21},"2026-05-31",{"name":156,"class":41},"Fujian Medical University",2,{"id":159,"slug":160,"hasResults":11,"nctId":161,"briefTitle":162,"officialTitle":163,"acronym":4,"eligibilityCriteria":164,"healthyVolunteers":165,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":166,"targetDuration":4,"studyType":22,"phases":168,"briefSummary":169,"conditions":170,"keywords":172,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":177,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":183,"locationsCount":66},"100586621","the-impact-of-immersive-virtual-reality-training-in-thyroid-surgery-100586621","NCT06917755","The Impact of Immersive Virtual Reality Training in Thyroid Surgery","The Impact of Immersive Virtual Reality Training in Thyroid Surgery: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Residents of the 2nd Surgical Department of Aristotle University of Thessaloniki\n* Residents who have completed their 1st year of training programm.\n\nExclusion Criteria:\n\n* Disagreement of participants' randomisation\n* Prolonged surgical time of completion\n* Participant's experience beyond the included limits\n* Participants who are completely incapable of using VR devices or have specific helath restrictions of using these\n* Patients with complex thyroid disease such as recurrent disease, concominant primary hyperparathyroidism, lymph node disease or metastasis, Graves disease and intrathoracic goiter",true,{"count":167,"type":21},12,[24],"Up to this date, there have been no reports on virtual reality (VR) training in thyroid surgery. The purpose of this study is to determine the impact of VR training in residents' education.\n\nInvestigators intend to include general surgery residents in the trial, subgrouped in a VR training group and another one with traditional learning, utilizing a technical textbook as a control. For the purpose of this study, a commercial available VR mask will be given for training in the VR group. Randomization will be used to secure balance in the distribution of residents according to their experience. The task which will be examined include surgical steps from neck incision up to the placement of the C-IONM electrode and will be evaluated by a blinded FEBS certified endocrine surgeon in the operating theatre.\n\nTraining superiority will be assessed by the outcome measures of Objective Structured Assessment of Technical Skills (OSATS) score, need for the main surgeon to intervene (NTI), verbal answers and time to task completion. Participants will complete questionnaires regarding satisfaction of the whole educational process.",[171,29],"Virtual Reality Simulation",[173,29,174,175],"Endocrine Surgery","Virtual Reality","Training","2025-04-09",{"date":178,"type":34},"2025-04-10",{"date":180,"type":34},"2025-02-20",{"date":182,"type":21},"2025-05-30",{"name":184,"class":41},"G.Gennimatas General Hospital",{"id":186,"slug":187,"hasResults":11,"nctId":188,"briefTitle":189,"officialTitle":189,"acronym":4,"eligibilityCriteria":190,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":191,"targetDuration":4,"studyType":22,"phases":193,"briefSummary":195,"conditions":196,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":197,"lastUpdatePostDateStruct":198,"startDateStruct":200,"completionDateStruct":202,"leadSponsor":204,"locationsCount":4},"100576767","phase-3-comparison-of-bupivacaine-wound-infiltration-versus-wound-instillation-to-minimize-postoperative-pain-after-thyroid-surgery-100576767","NCT06789575","Comparison of Bupivacaine Wound Infiltration Versus Wound Instillation to Minimize Postoperative Pain After Thyroid Surgery","Inclusion Criteria:\n\n* Normal thyroid function patients of both genders scheduled for thyroid surgery will included in this study\n* If they are over the age of 18\n* If they had an ASA score (American Society of Anesthesiology) I, II.\n* A Score of Mallampati I , II.\n\nExclusion Criteria:\n\n* Patient refused to participate in the study.\n* Patients will be excluded if they have any analgesic medication or corticosteroid drug prior surgery or\n* A known or suspected allergy to local anesthetics,\n* if the duration of surgery is greater than 5 h and if a major complication of surgery or anesthesia (major bleeding, allergy to anesthetic products).\n* Patients who have lateral neck dissection associated with Thyroid surgery are excluded.",{"count":192,"type":21},102,[194],"PHASE3","Pain management following thyroidectomies, which can cause mild to moderate postoperative pain, particularly in the first 24 hours following surgery, has received little attention . The incision of the wound, neck hyperextension, retraction of the wound margins during surgery, and dissection are the main reasons of post-thyroidectomy discomfort . After thyroid surgery, pain management improves patients' quality of life and facilitates a speedy return to regular daily activities.\n\nthe aim of the study to evaluate the effects of bupivacaine instillation after thyroidectomy against infiltration into the surgical field in order to reduce postoperative discomfort following thyroid surgery.",[29],"2025-01-18",{"date":199,"type":34},"2025-01-23",{"date":201,"type":21},"2025-03-01",{"date":203,"type":21},"2027-05-01",{"name":205,"class":41},"Assiut University",{"id":207,"slug":208,"hasResults":11,"nctId":209,"briefTitle":210,"officialTitle":211,"acronym":4,"eligibilityCriteria":212,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":213,"enrollmentInfo":214,"targetDuration":4,"studyType":22,"phases":216,"briefSummary":217,"conditions":218,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":221,"lastUpdatePostDateStruct":222,"startDateStruct":224,"completionDateStruct":226,"leadSponsor":228,"locationsCount":4},"100574891","randomized-controlled-trial-comparing-drains-usage-vs-without-drains-after-thyroid-surgery-100574891","NCT06765174","Randomized Controlled Trial Comparing Drains Usage vs Without Drains After Thyroid Surgery","Drain vs no Drain After Thyroid Surgeries: a Prospective Randomized Clinical Trial.","Inclusion Criteria:\n\n* (1) Male or female patients undergoing thyroidectomy (2) Patients with ages: from 18 to 60 years old. (3) Patients with normal thyroid function tests (4) Patients who are fit for general-anesthesia.\n\nExclusion Criteria:\n\n* (1) Patients with bleeding diathesis and those on anticoagulants. (2) Patients with thyrotoxicosis (uncontrolled) (3) Patients those requiring neck L.N dissection. (4) Patients with previous neck surgeries. (5) Patients with severe comorbid conditions with high risk for general anesthesia.","60 Years",{"count":215,"type":21},40,[24],"The aim of this study is to compare patients who used drain to patients who did not use drain post-thyroidectomy regarding the short-term outcomes .",[29,219,220],"Drains","Post Thyroidectomy Complications","2025-01-03",{"date":223,"type":34},"2025-01-09",{"date":225,"type":21},"2025-12",{"date":227,"type":21},"2027-01",{"name":205,"class":41}]