[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tmj-disc-displacement-with-reduction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tmj-disc-displacement-with-reduction":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100634083","ultrasound-guided-versus-arthroscopic-guided-prf-injection-for-tmj-disc-displacement-100634083",false,"NCT07535073","Ultrasound-guided Versus Arthroscopic Guided PRF Injection for TMJ Disc Displacement.","Ultrasound Guided Versus Arthroscopic Guided PRF Injection in Management of Temporomandibular Joint Disc Displacement With Reduction: A Randomized Controlled Clinical Trials","Inclusion Criteria:\n\n* Patients aged 18-60 years.\n* Clinically and radiographically diagnosed temporomandibular joint disc displacemet with reduction.\n* Presence of TMJ pain exacerbated by mandibular movement.\n* Limited mandibular function and\u002For reduced maximum mouth opening.\n* Symptoms persisting for at least 3 months.\n* Failure of conservative treatment (e.g. occlusal splint, physiotherapy, NSAIDs). -Ability to understand the study protocol and provide informed consent.\n\nExclusion Criteria:\n\n* Previous TMJ surgery or arthroscopic intervention.\n* Intra-articular injection in the TMJ within the last 6 months.\n* Systemic inflammatory or autoimmune joint diseases.\n* Coagulation disorders or current anticoagulant therapy.\n* Active local infection at the injection site.\n* Pregnancy or lactation.\n* Severe degenerative joint disease (advanced osteoarthritis).\n* Known allergy or contraindication to ( PRF) preparation.","ALL","18 Years","60 Years",{"count":20,"type":21},18,"ESTIMATED","INTERVENTIONAL",[24],"NA","To compare the clinical effectiveness of ultrasound-guided versus arthroscopic guided platelet rich fibrin injection in the management of anterior disc displacement with reduction of the temporomandibular joint, in terms of pain reduction, improvement of mandibular function, and patient-reported outcomes.",[27],"TMJ Disc Displacement With Reduction",[29,30,31],"temporomandibular joint","Tmj disc displacement","PRF","NOT_YET_RECRUITING","2026-04-09",{"date":35,"type":36},"2026-04-16","ACTUAL",{"date":38,"type":21},"2026-05-07",{"date":40,"type":21},"2027-06-07",{"name":42,"class":43},"Cairo University","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":4},"100601845","ars-vs-ars-with-arthrocentesis-and-prp-injection-in-ddwr-100601845","NCT07115797","ARS vs ARS With Arthrocentesis and PRP Injection in DDWR","Anterior Repositioning Splint With or Without Arthrocentesis and Platelet-rich Plasma Injection In TMD Patients With Anterior Disc Displacement With Reduction: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Patients suffering from internal derangement anterior disc displacement\n* Mouth Opening: Limited range of motion or difficulty with full mouth opening\n* Symptoms: Patients who report typical symptoms of TMJ dysfunction, such as pain, discomfort, or clicking sounds in the joint, especially when opening or closing the mouth.\n* Clicking: Audible clicking.\n* Pain: Pain or tenderness around the TMJ, often radiating to the ear, temple, or neck.\n\nExclusion Criteria:\n\n* Blood dyscrasias and Uncontrolled systemic diseases.\n* Rheumatoid Arthritis.\n* Infection in the pre-auricular area.",true,{"count":53,"type":21},20,[24],"This study will be conducted to assess the effect of anterior repositioning splint and arthrocentesis with platelet-rich plasma injection compared to anterior repositioning splint only, in TMD patients with anterior disc displacement with reduction",[27,57,58],"TMD","PRP Injection",[60],"ARS-PRP-Arthrocentsis","2025-08-04",{"date":63,"type":36},"2025-08-11",{"date":65,"type":21},"2025-09",{"date":67,"type":21},"2026-10",{"name":42,"class":43},{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":16,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":80,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":4},"100580602","therapeutic-effect-of-using-injectable-hypertonic-saline-5-versus-injectable-dextrose-20-on-pain-in-painful-cases-of-disc-displacement-with-reduction-100580602","NCT06839430","Therapeutic Effect of Using Injectable Hypertonic Saline 5% Versus Injectable Dextrose 20% on Pain in Painful Cases of Disc Displacement With Reduction","Therapeutic Effect of Using Injectable Hypertonic Saline 5% Versus Injectable Dextrose 20% on Pain in Painful Cases of Disc Displacement With Reduction ( A Randomized Clinical Trial)","RCT","Inclusion Criteria:\n\n* presence of one or more of the following observations in one or both temporomandibular joints:\n\n  1. pain.\n  2. audible clicking.\n  3. mandibular deviation on opening.\n  4. Failure of conservative treatment\n\nExclusion Criteria:\n\n* The clinical or radiographic signs of disc displacement without reduction, osteoarthritis, or articular bony changes.\n\n  * Previous TMJ surgery, arthrocentesis, , or the presence of any systemic disease that would affect the TMJ anatomy or mechanical function.\n  * A history of allergic reactions to any components of the injectable solution.\n  * Infection of the affected joint and pre-auricular area.\n  * Previous surgery of the affected joint","15 Years","75 Years",{"count":53,"type":21},[24],"This study is aiming to assess effect of hypertonic saline 5% in comparison to dextrose 20% on pain ,inter-insical opening and movements of jaw in painful cases of disc displacement with reduction",[27],"2025-03-06",{"date":85,"type":36},"2025-03-07",{"date":87,"type":21},"2025-08-20",{"date":89,"type":21},"2026-09-20",{"name":42,"class":43}]