[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tobacco-smoking-behavior\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tobacco-smoking-behavior":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":5},"100552225","biopsychosocial-predictors-of-nicotine-relapse-100552225",false,"NCT06470321","Biopsychosocial Predictors of Nicotine Relapse","Identifying Biomarkers of Stress-induced Neurophysiological Changes and Emotion Regulation Deficits to Predict Relapse During Nicotine Abstinence","BioNic","Inclusion Criteria:\n\n* Age 18-60 years\n* Smoking at least 10 cigarettes daily for at least 2 years\n* Intention to quit smoking\n* Medication-free\n\nExclusion Criteria:\n\n* Presence of psychiatric or medical treatment\n* Pregnancy\n* Current unstable medical illness\n* Recent (prior 6 months) drug or alcohol use disorder\n* Major Depression\n* Diagnosis of psychotic disorder","ALL","18 Years","60 Years",{"count":21,"type":22},200,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to investigate the associations between emotion regulation ability, stress-induced neural activity changes, and susceptibility to relapse in smokers attempting to quit. Participants will undergo assessments of emotion regulation, neural activity via quantitative electroencephalography (qEEG), and stress responses before and during a 24-hour nicotine abstinence period. They will then participate in a computerized smoking cessation intervention, and their abstinence status will be monitored for 6 months.",[28,29,30,31],"Smoking","Smoking Cessation","Nicotine Addiction","Tobacco Smoking Behavior",[33,34,35,36,37,38,39],"Nicotine","Relapse","Vulnerability","Biomarkers","EEG","HRV","Stress Reactivity","RECRUITING","2024-06-17",{"date":43,"type":44},"2024-06-24","ACTUAL",{"date":46,"type":44},"2022-01-01",{"date":48,"type":22},"2025-05-01",{"name":50,"class":51},"University of Cyprus","OTHER"]