[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tonsil-hypertrophy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tonsil-hypertrophy":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100639804","randomized-clinical-trial-for-tonsil-surgery-in-adults-with-obstructive-sleep-apnea-and-enlarged-tonsils-100639804",false,"NCT07580170","Randomized Clinical Trial for Tonsil Surgery in Adults With Obstructive Sleep Apnea and Enlarged Tonsils","Multicenter, National, Randomized, Patient-Blinded, Parallel Group, Non-Inferiority Trial To Compare Tonsillotomy Versus Extracapsular Tonsillectomy in Adults With Obstructive Sleep Apnea and Tonsil Hypertrophy: The TONOS Trial.","TONOS","Inclusion Criteria:\n\n* BMI \\\u003C 35\n* Tonsil size 2 - 4\n* Otherwise healthy patient fit for tonsil surgery\n* Apnea-hypopnea index \\> 15\n* Obstructive sleep apnea symptoms\n\nExclusion Criteria:\n\n* Pathological hemostasis or use of anticoagulation\n* Craniofacial deformities\n* Neurological condition with muscular hypotonia\n* Other surgical treatment for OSA","ALL","18 Years","65 Years",{"count":21,"type":22},132,"ESTIMATED","INTERVENTIONAL",[25],"NA","The aim is to investigate whether the tissue-preserving tonsil surgery technique is as effective as complete tonsil removal in the treatment of obstructive sleep apnea. The primary outcome measure is the change in the apnea-hypopnea index (AHI) before surgery and at 4-6, 24, and 60 months after surgery.",[28,29],"Sleep Apnea, Obstructives","Tonsil Hypertrophy",[31,32,33,34,35,36],"sleep apnea","tonsillectomy","tonsillotomy","intracapsular tonsillectomy","adults","tonsil hypertrophy","NOT_YET_RECRUITING","2026-05-31",{"date":40,"type":41},"2026-06-03","ACTUAL",{"date":43,"type":22},"2026-10-01",{"date":45,"type":22},"2036-01-01",{"name":47,"class":48},"Turku University Hospital","OTHER_GOV",4,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":23,"phases":62,"briefSummary":63,"conditions":64,"keywords":65,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":80},"100615963","effect-of-the-combination-of-dexamethasone-and-bis-monitoring-on-reducing-postoperative-nausea-and-vomiting-in-children-100615963","NCT07299435","Effect of the Combination of Dexamethasone and BIS Monitoring on Reducing Postoperative Nausea and Vomiting in Children","Effect of the Combination of Dexamethasone and BIS Monitoring on Reducing Postoperative Nausea and Vomiting in Children: a Multicenter Prospective Double-blind Study (BISDEX TRIAL)","BISDEX","Inclusion Criteria:\n\n* children aged 2 to 8 years undergoing endoscopic adenoidectomy\n* parental\u002Fchild consent\n* ASA I-II (American Society of Anaesthesiologists Physical Status)\n* no central nervous system (CNS) or gastrointestinal tract (GIT) disease\n* no corticosteroid medication\n\nExclusion Criteria:\n\n* Parent\u002Fchild disapproval\n* ASA III and above (American Society of Anaesthesiologists Physical Status)\n* central nervous system (CNS) or gastrointestinal tract (GIT) disease\n* chronic corticosteroid therapy","2 Years","8 Years",{"count":61,"type":22},1508,[25],"This study will investigate the impact of combining dexamethasone and bispectral index (BIS) monitoring on the incidence of postoperative nausea and vomiting, emergence delirium and recovery trajectories in children undergoing ear-nose-throat (ENT) surgery.",[29],[66,67,68,69],"postoperative nausea and vomiting","emergence delirium","children","ENT surgery","2025-12-09",{"date":72,"type":41},"2025-12-23",{"date":74,"type":22},"2026-01-05",{"date":76,"type":22},"2029-01",{"name":78,"class":79},"University Hospital Ostrava","OTHER",5]