[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tonsillar-hypertrophy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tonsillar-hypertrophy":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,52,88,119,148,173],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100635427","full-wrap-versus-conventional-suspension-for-reducing-soft-palate-injury-rate-100635427",false,"NCT07552545","Full-wrap Versus Conventional Suspension for Reducing Soft Palate Injury Rate","Full-wrap Versus Conventional Suspension for Reducing Soft Palate Injury Rate in Transoral Surgery: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Voluntarily sign the informed consent form; for patients aged \\\u003C18 years, the informed consent form must be signed by their legal guardian.\n* Age between 2 and 70 years (inclusive), male or female.\n* Patients requiring transoral surgery of the nose, pharynx, parapharyngeal space, or skull base, in which intraoperative soft palate suspension is needed.\n* Intact soft palate mucosa with no ulcers, scars, or other lesions before surgery.\n\nExclusion Criteria:\n\n* Congenital cleft palate or submucous cleft palate.\n* Patients with limited cervical spine mobility, micrognathia, or other conditions affecting surgical exposure.\n* Pregnant or breastfeeding women.\n* Presence of markedly abnormal laboratory test results, such as significant abnormalities in routine blood tests, blood biochemistry, liver and kidney function, or coagulation function.\n* Patients with active infection or infectious diseases.\n* Severe cardiac insufficiency (NYHA class III-IV).\n* Other conditions deemed unsuitable for surgery after evaluation (e.g., concomitant severe heart, brain, or lung diseases; high anesthetic risk; patients not fit for surgery).","ALL","2 Years","70 Years",{"count":20,"type":21},138,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to evaluate whether the use of full-wrap suspension, compared with the traditional double-strap suspension, can effectively reduce the risk of intraoperative and postoperative soft palate injury in transoral\u002Ftransnasal pharyngeal surgery. Through a prospective, multicenter, randomized controlled design, this study will provide evidence-based support for the clinical promotion and standardized application of full-wrap suspension.",[27,28,29,30,31,32],"Adenoid Hypertrophy","Tonsillar Hypertrophy","Nasopharyngeal Diseases","Nasopharyngeal Tumors","Parapharyngeal or Skull Base Lesions","Required Soft Palate Suspension",[34,35,36,37,38],"soft plate injury","Transoral pharyngeal surgery","Soft palate suspension","Randomized controlled trial","Full-wrap suspension","NOT_YET_RECRUITING","2026-05-05",{"date":42,"type":43},"2026-05-08","ACTUAL",{"date":45,"type":21},"2026-04-30",{"date":47,"type":21},"2027-10-31",{"name":49,"class":50},"Sun Yat-sen University","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":16,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":22,"phases":63,"briefSummary":64,"conditions":65,"keywords":72,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":87},"100483466","lateral-pharyngoplasty-outcomes-in-children-undergoing-tonsillectomy-100483466","NCT05575401","Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy","Post-operative Outcomes of Tonsillectomy With Lateral Pharyngoplasty Versus Tonsillectomy Alone in Children: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Participants ages 3-17 years of age undergoing tonsillectomy +\u002F- adenoidectomy at Loma Linda University Health\n\nExclusion Criteria:\n\n* Subjects with congenital syndromes and\u002For developmental delay\n* Subjects with cancer\n* Subjects with gastrostomy tube use or dependence\n* Subjects undergoing intracapsular tonsillectomy","3 Years","17 Years",{"count":62,"type":21},160,[24],"The goal of this treatment study is to determine if doing lateral pharyngoplasty with tonsillectomy is better for children than doing tonsillectomy alone. The main questions it aims to answer are:\n\n* Do children experience less pain after surgery when lateral pharyngoplasty is performed with tonsillectomy compared to tonsillectomy alone?\n* Do children eat\u002Fdrink better when lateral pharyngoplasty is performed with tonsillectomy compared to tonsillectomy alone?\n* Is there a lower risk of bleeding after tonsillectomy when lateral pharyngoplasty is performed? Researchers will compare children undergoing tonsillectomy and lateral pharyngoplasty with children undergoing tonsillectomy alone to see if the participants experience less pain, better oral intake, and less bleeding complications after surgery. Parents of participants will be asked to record pain scores and pain medications given, approximate amounts of daily oral intake, and any complications after surgery.",[66,67,68,69,28,70,71],"Sleep-Disordered Breathing","Sleep Apnea Syndromes in Children","Sleep Apnea, Obstructive","Tonsillitis","Tonsil Stone","Tonsil Disease",[73,74,75,76],"Tonsillectomy","Post-tonsillectomy hemorrhage","Post-tonsillectomy complication","Lateral pharyngoplasty","RECRUITING","2026-02-19",{"date":80,"type":43},"2026-02-23",{"date":82,"type":43},"2023-05-17",{"date":84,"type":21},"2026-12",{"name":86,"class":50},"Loma Linda University",4,{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":16,"minAge":95,"maxAge":96,"enrollmentInfo":97,"targetDuration":4,"studyType":99,"phases":4,"briefSummary":100,"conditions":101,"keywords":103,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":51},"100623623","evaluation-of-the-effects-of-adenoidectomy-and-adenotonsillectomy-on-voice-in-children-100623623","NCT07399041","Evaluation of the Effects of Adenoidectomy and Adenotonsillectomy on Voice in Children","A Prospective Single-Center Study Evaluating the Effects of Adenoidectomy and Adenotonsillectomy on Voice and Speech Functions in Children","Inclusion Criteria:\n\n* Aged 4-13 years\n* Scheduled for primary adenoidectomy or adenotonsillectomy\n\nExclusion Criteria:\n\n* Does not meet inclusion criteria\n* Refuses to participate in the study\n* Diagnosis of vocal cord disorders\n* History of vocal cord surgery\n* History of cleft palate or cleft lip\n* Hearing loss requiring a hearing aid\n* Chronic diseases that may impair wound healing, including: hypertension, diabetes mellitus, immunodeficiency, autoimmune diseases, rheumatologic diseases, connective tissue disorders, renal failure, liver failure, chronic heart disease\n* Known bleeding diathesis\n* Use of anticoagulant or antiplatelet drugs\n* Upper respiratory tract infection within the last 2 weeks\n* Patients undergoing revision adenoidectomy","4 Years","13 Years",{"count":98,"type":21},36,"OBSERVATIONAL","This prospective study aims to evaluate the effects of adenoidectomy and adenotonsillectomy on voice and speech functions in children. Changes in voice quality and resonance may occur after the removal of adenoid and tonsillar tissues, particularly in pediatric patients with enlarged adenoids or tonsils.\n\nObjective voice assessments, including acoustic, aerodynamic, and nasalance measurements, as well as subjective voice-related quality of life questionnaires, will be performed before surgery and at the first and third months after surgery. The results of this study are expected to help clinicians better inform families about possible voice changes following adenoidectomy and adenotonsillectomy procedures.",[27,28,102],"Voice Disorders in Children",[104,105,106,107,108],"Adenoidectomy","Adenotonsillectomy","Pediatric Voice","Nasalance","praat","2026-02-02",{"date":111,"type":43},"2026-02-10",{"date":113,"type":21},"2026-02",{"date":115,"type":21},"2026-08",{"name":117,"class":118},"Gaziosmanpasa Research and Education Hospital","OTHER_GOV",{"id":120,"slug":121,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":124,"acronym":125,"eligibilityCriteria":126,"healthyVolunteers":127,"sex":16,"minAge":59,"maxAge":60,"enrollmentInfo":128,"targetDuration":4,"studyType":22,"phases":130,"briefSummary":132,"conditions":133,"keywords":136,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":51},"100560414","phase-4-optimization-of-pediatric-tonsillectomy-to-improve-analgesia-100560414","NCT06576830","Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia","Single-Dose Intraoperative Methadone for Pain Management in Pediatric Tonsillectomy: A Randomized Double Blind Clinical Trial","OPTIMAL","Inclusion Criteria:\n\n1. Age \\>= 3 and \\\u003C 18 years\n2. Elective tonsillectomy +\u002F- adenoidectomy\n3. Signed informed consent by parent or legal guardian\n4. Children \\>= 12 years must provide signed written consent, Children \\>= 7 years must provide verbal assent\n5. Negative pregnancy test within 48 hours for post pubescent females\n\nExclusion Criteria:\n\n1. History of chronic kidney or liver disease\n2. Current diagnosis of a chronic pain disorder\n3. Planned admission to the Pediatric Intensive Care Unit (PICU)\n4. Additional procedures under general anesthesia for which opioids would be prescribed",true,{"count":129,"type":21},440,[131],"PHASE4","The purpose of this study is to compare the use of short acting opioids (fentanyl\u002Fhydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.",[134,28,69,135,66],"Pain, Postoperative","Pediatric Sleep Apnea",[137,73,138],"Methadone","Opioid","2025-12-01",{"date":141,"type":43},"2025-12-05",{"date":143,"type":43},"2024-11-21",{"date":145,"type":21},"2029-06-01",{"name":147,"class":50},"Duke University",{"id":149,"slug":150,"hasResults":11,"nctId":151,"briefTitle":152,"officialTitle":153,"acronym":4,"eligibilityCriteria":154,"healthyVolunteers":127,"sex":16,"minAge":155,"maxAge":4,"enrollmentInfo":156,"targetDuration":4,"studyType":99,"phases":4,"briefSummary":158,"conditions":159,"keywords":160,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":164,"lastUpdatePostDateStruct":165,"startDateStruct":167,"completionDateStruct":169,"leadSponsor":171,"locationsCount":51},"100608753","self-assessment-of-tonsil-size-100608753","NCT07205653","Self-assessment of Tonsil Size","Validity of Patients' Self-assessment of Tonsil Size","Exclusion Criteria:\n\n* Experience in clinical work with patients\n* Prior tonsillectomy","18 Years",{"count":157,"type":21},90,"The participants receive instructions on two tonsil size classification scales and then, using a tongue depressor as well as their mobile phone camera and\u002For a flashlight and a mirror, the participants assess the size of their own tonsils on two scales.\n\nAfter the self-assessment, a medical student and two ear, nose, and throat (ENT) specialists evaluate the participants' tonsil size using a tongue depressor and a headlamp, applying the same scales.\n\nThe objective of this study is to demonstrate that patient self-assessment constitutes a sufficiently accurate method for evaluating tonsil size. Furthermore, it aims to show that patients experiencing conditions such as sleep apnea or swallowing difficulties can, on the basis of their own assessment, be appropriately referred to an otolaryngologist for surgical evaluation, thereby conserving healthcare resources and reducing the time burden for patients.",[28],[161,162,163],"tonsil size","tonsillar hypertrophy","self-assessment","2025-10-02",{"date":166,"type":43},"2025-10-03",{"date":168,"type":21},"2025-10-20",{"date":170,"type":21},"2026-01-01",{"name":172,"class":118},"Turku University Hospital",{"id":174,"slug":175,"hasResults":11,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":4,"eligibilityCriteria":179,"healthyVolunteers":11,"sex":16,"minAge":155,"maxAge":180,"enrollmentInfo":181,"targetDuration":4,"studyType":22,"phases":183,"briefSummary":184,"conditions":185,"keywords":187,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":4},"100545014","tonsillectomy-vs-tonsillotomy-in-adults-with-obstructive-sleep-apnea-100545014","NCT06376383","Tonsillectomy vs. Tonsillotomy in Adults With Obstructive Sleep Apnea","Tonsillectomy Versus Tonsillotomy in Adults With Obstructive Sleep Apnea; a Randomized Controlled Trial Comparing Postoperative Morbidity","Inclusion Criteria:\n\n* Age \\> 18 years\n* Tonsil size 2, 3, or 4 (Friedman tonsil scale)\n* Confirmed OSA with sleep analysis not older than a year either CRM or PSG\n* ASA 1 or 2\n* BMI \\\u003C 35 kg\u002Fm2\n\nExclusion Criteria:\n\nChildren age \\\u003C 18 years\n\n* Previous pharyngeal surgery such as previous tonsillotomy, tonsillectomy or palatal surgery\n* Epileptic disease or severe neurological comorbidity.\n* ASA 3, or 4.\n* Central sleep apnea\n* Previous thrombotic disease.\n* Currently treated with sleep medications\n* No collapse of oropharyngeal lateral wall during DISE\n* Dropout of study, lack of sleep analysis or lack of postoperative DISE.","65 Years",{"count":182,"type":21},464,[24],"The primary purpose of this randomized controlled trial s to investigate whether surgical reduction of palatine tonsils (tonsillotomy) is a superior treatment compared to complete surgical removal of palatine tonsils (tonsillectomy) in adults patients with obstructive sleep apnea and concomitant enlarged tonsils in regards of perioperative and postoperative morbidity.",[186,28],"Obstructive Sleep Apnea",[73,188,189,190,191],"Obstructive sleep apnea (OSA)","Tonsillotomy","Intracapsular reduction of tonsils","Drug Induced Sedation Endoscopy","2024-04-18",{"date":194,"type":43},"2024-04-19",{"date":196,"type":21},"2025-01",{"date":198,"type":21},"2027-09",{"name":200,"class":50},"University of Aarhus"]