[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tonsillectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tonsillectomy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,46,70,97,117,139,169,193,219,240,266],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100643818","coblator-wand-comparative-analysis-100643818",false,"NCT07635719","Coblator Wand Comparative Analysis","Comparative Analysis of Efficiency, Technical Performance, and Environmental Cost Between Reprocessed and New Coblator Wands in Intracapsular Tonsillectomies and Adenoidectomies","Inclusion Criteria:\n\n* Pediatric patients scheduled for tonsillectomy and\u002For adenoidectomy\n* Parental consent and child assent (when applicable)\n\nExclusion Criteria:\n\n* Pregnancy","ALL","1 Year","18 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will address the gap in coblator wands by comparing the performance of reprocessed coblator wands with new wands in terms of efficiency and technical issues. As part of the evaluation, the investigator team will conduct the technical performance of the life cycle assessment of reprocessed versus new coblation wands based on the methodology described in the literature (see References) in studies of laryngoscopes.",[27,28],"Tonsillectomy","Adenoidectomy",[30,31,32],"Coblator wand","Product performance","Usability","NOT_YET_RECRUITING","2026-06-03",{"date":36,"type":37},"2026-06-09","ACTUAL",{"date":39,"type":21},"2026-06",{"date":41,"type":21},"2026-12",{"name":43,"class":44},"Montefiore Medical Center","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":45},"100633482","effects-of-adenoidectomy-on-symptoms-and-ige-levels-in-children-with-ar-100633482","NCT07527260","Effects of Adenoidectomy on Symptoms and IgE Levels in Children With AR","Effects of Adenoidectomy With or Without Tonsillectomy on Symptoms and Local IgE Levels in Children With Allergic Rhinitis","Inclusion Criteria:\n\n\\- 3-12 years\n\n1. Children with physician-diagnosed allergic rhinitis and typical symptoms (nasal obstruction, watery rhinorrhea, paroxysmal sneezing);\n2. Co-existing adenoidal and tonsillar hypertrophy meeting surgical indications;\n3. No systemic or topical corticosteroids, leukotriene antagonists, or antihistamines within the past 3 months.\n\nExclusion Criteria:\n\n1. Prior adenoidectomy, tonsillectomy, or radio-frequency ablation;\n2. Nasal polyps, cystic fibrosis, primary ciliary dyskinesia, fungal rhinosinusitis, systemic vasculitis\u002Fgranulomatosis, tumor, or immunodeficiency;\n3. Endoscopic nasal surgery within 6 months or severe asthma precluding surgery;\n4. Upper respiratory infection within 4 weeks;\n5. Serious metabolic, cardiovascular, immune, neurologic, hematologic, gastrointestinal, cerebrovascular, or respiratory disease, or any condition judged by the investigator to interfere with outcome assessment or participant safety;\n6. Currently enrolled or within 30 days of participation in another clinical trial.","3 Years","12 Years",{"count":56,"type":21},36,[24],"This study aims to evaluate the effects of conservative management versus surgical intervention (adenoidectomy alone or adenotonsillectomy) on symptoms and local IgE levels in children with allergic rhinitis (AR) accompanied with adenotonsillar hypertrophy. The primary objectives include the impact of conservative management and surgical interventions on AR symptoms and local IgE levels. The second outcomes include serum IgE levels, inflammatory cell profiles within the nasal mucosa, and postoperative complications.",[28,27,60],"Allergic Rhinitis","2026-04-13",{"date":63,"type":37},"2026-04-14",{"date":65,"type":21},"2026-04-11",{"date":67,"type":21},"2027-04-01",{"name":69,"class":44},"Tongji Hospital",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":16,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":81,"briefSummary":82,"conditions":83,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":93,"leadSponsor":95,"locationsCount":45},"100630597","ondansetron-lozenge-versus-intravenous-for-prevention-of-shivering-in-tonsillectomy-100630597","NCT07489742","Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Tonsillectomy","Effect of Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Tonsillectomy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age from 4 to 15 years.\n* Both sexes.\n* American Society of Anesthesiology (ASA) physical status I-II.\n* Children undergoing tonsillectomy under general anesthesia.\n\nExclusion Criteria:\n\n* Allergy to ondansetron.\n* History of sleep apnea.\n* Cardiac and respiratory diseases.\n* Upper respiratory tract infection.\n* Taking corticosteroids.","4 Years","15 Years",{"count":80,"type":21},210,[24],"This study aims to compare the effect of ondansetron lozenge and intravenous for prevention of shivering in tonsillectomy.",[84,85,86,87,27],"Ondansetron","Lozenge","Intravenous","Shivering","RECRUITING","2026-03-25",{"date":91,"type":37},"2026-03-27",{"date":89,"type":37},{"date":94,"type":21},"2026-09-01",{"name":96,"class":44},"Tanta University",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":16,"minAge":103,"maxAge":18,"enrollmentInfo":104,"targetDuration":4,"studyType":106,"phases":4,"briefSummary":107,"conditions":108,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":45},"100630953","adenoidectomy-correlation-between-individual-factors-surgical-technique-and-residual-adenoids-100630953","NCT07494370","Adenoidectomy: Correlation Between Individual Factors, Surgical Technique, and Residual Adenoids","Inclusion Criteria:\n\n* Pediatric patients evaluated at the upper airway endoscopy clinic who are candidates for adenoidectomy","0 Years",{"count":105,"type":21},1200,"OBSERVATIONAL","Adenoidectomy is the most commonly performed otolaryngological surgical procedure in children. The removal of adenoid lymphoid tissue is intended to clear the nasopharynx and restore the patency of the nasal airways. In most cases, adenoidectomy leads to an improvement in symptoms and quality of life. However, in some patients, symptoms recur with the presence of lymphoid tissue obstructing the nasopharynx. In these cases, a surgical revision is often necessary.\n\nThe traditional surgical technique is performed using an adenoid curette or Shambaugh adenotome without direct visualization of the surgical field. Among the known limitations of this surgery is the possibility of leaving intraoperative adenoid residues. In the literature, regarding the detection of adenoid vegetations in patients who have already undergone adenoidectomy, the term \"regrowth\" of lymphoid tissue is often used; however, this term is correctly applied only when there is certainty of complete adenoid excision during the procedure. In the absence of this certainty, it would therefore be more accurate to speak of persistence or recurrence of adenoid hypertrophy after adenoidectomy. However, this phenomenon is poorly understood due to the scarcity of information in the literature regarding the incidence, associated factors, and etiology of this clinical entity. In particular, there is still debate over whether the recurrence of symptoms following the detection of nasopharyngeal lymphoid tissue is due to incomplete surgical resection, or whether individual factors may coexist and contribute to the recurrence of adenoid lymphoid tissue. To date, the scientific literature has focused almost exclusively on intraoperative variables independent of the patient. The aim of this study is to evaluate whether there are patient-specific factors at the time of surgery-such as sex, age, weight, height, and soft palate length-that may influence the surgical efficacy of the traditional technique in terms of complete removal of adenoid lymphoid tissue.",[27],"2026-03-20",{"date":91,"type":37},{"date":112,"type":37},"2020-08-20",{"date":114,"type":21},"2026-08-20",{"name":116,"class":44},"Fondazione IRCCS Policlinico San Matteo di Pavia",{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":4,"eligibilityCriteria":123,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":18,"enrollmentInfo":124,"targetDuration":4,"studyType":22,"phases":126,"briefSummary":127,"conditions":128,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":45},"100619644","head-only-draping-in-pediatric-tonsillectomy-100619644","NCT07347301","Head-Only Draping in Pediatric Tonsillectomy","30-Day Postoperative Infection Rate in Pediatric Tonsillectomy: Head-Drape vs. Full-Body Surgical Draping","Inclusion Criteria:\n\n1. Pediatric patients \\\u003C18 years at time of surgery.\n2. Scheduled for tonsillectomy, with or without adenoidectomy, without any other procedures requiring full-body draping.\n3. Ability to complete 30-day outcome assessment (i.e., remain in follow-up or reachable via phone\u002Felectronic health record).\n4. Parent\u002Fguardian able to provide parental permission and consent for both them and their children.\n\nExclusion Criteria:\n\n1. Significant deviation from planned surgical technique during case.\n2. Pre-existing systemic infection prior to surgery.\n3. Known immunodeficiency or current systemic immunosuppressive therapy.",{"count":125,"type":21},200,[24],"This single-center, interventional study will compare 30-day postoperative infection rates in pediatric tonsillectomy performed with either head-only draping or traditional full-body draping. Secondary analyses will evaluate differences in waste production, material and disposal costs, and provider attitudes between the two draping techniques. This study will randomize participants 1:1 to either the head-only draping cohort (intervention) or the full-body draping cohort (control).",[27,129],"Infections","2026-01-09",{"date":132,"type":37},"2026-01-16",{"date":134,"type":21},"2026-02-02",{"date":136,"type":21},"2026-12-01",{"name":138,"class":44},"NYU Langone Health",{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":4,"eligibilityCriteria":145,"healthyVolunteers":146,"sex":16,"minAge":53,"maxAge":54,"enrollmentInfo":147,"targetDuration":4,"studyType":22,"phases":149,"briefSummary":151,"conditions":152,"keywords":158,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":4},"100618782","phase-3-melatonin-vs-midazolam-in-children-undergoing-tonsillectomy-100618782","NCT07336095","Melatonin vs Midazolam in Children Undergoing Tonsillectomy","Effect of Oral Melatonin Versus Oral Midazolam as a Premedication in Children Undergoing Tonsillectomy","Inclusion Criteria:\n\n-ALL children with ASA class I and class II\n\nExclusion Criteria:\n\n* chest infection\n* Abnormal mental milestones.\n* Children with any organ dysfunction.\n* Allergies to any of the drugs used.\n* Children with Obstructive sleep apnea.",true,{"count":148,"type":21},195,[150],"PHASE3","Used as a premedication to decrease anxiety (Caumo et al., 2007). Midazolam, though has several drawbacks (McCann and Kain, 2001). Hence, an alternative premedication to midazolam will definitely have a widespread appeal.\n\nMelatonin is a hormone secreted by the pineal gland. Melatonin is different from benzodiazepines and their derivatives in that it exerts a promoting effect on sleep by amplifying day\u002Fnight differences in alertness and sleep quality and displaying a modest sleep-inducing effect, quite mild as compared to that seen with benzodiazepines (Ahmad et al., 2007). Melatonin has also been reported to cause preoperative anxiolysis and an increase in levels of sedation without impairing orientation (Naguib and Samarkandi, 2000). Hence, the aim of this study is to compare the effect of oral melatonin and oral midazolam on preoperative anxiety.\n\nEmergence delirium (ED) was first described in the literature in the early 1960s. Although often used interchangeably with emergence agitation, it is defined as a temporary dissociated state of consciousness after discontinuation of anesthesia. The characteristics that make up ED include irritability, inconsolable crying, distress and inability to cooperate (Reduque and Verghese, 2013).\n\nMidazolam is the most prescribed oral premedication in the preoperative setting. Its benefits include preoperative anxiolysis, amnesia, relatively rapid onset and short duration of action. Although most children have anxiolysis with midazolam, up to 29% may display a paradoxical agitation response (Shin et al., 2013).\n\nOral melatonin doses up to 0.4 mg\u002Fkg (maximum 20 mg) are effective in reducing ED in children (age 3-7 years) (Kain et al., 2009).\n\nAIM OF THE WORK The study aims to compare the effects of oral melatonin and oral midazolam on preoperative anxiety as a premedication in children undergoing tonsillectomy.",[153,154,155,156,157,27],"Emergence Delirium, Anesthesia","Child","Anxiety","Midazolam Premedication","Melatonin Bioavailability",[159],"melatonin, midazolam, anxiety, children, tonsillectomy","2026-01-02",{"date":162,"type":37},"2026-01-13",{"date":164,"type":21},"2026-03-01",{"date":166,"type":21},"2026-08",{"name":168,"class":44},"Ain Shams University",{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":174,"acronym":4,"eligibilityCriteria":175,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":176,"enrollmentInfo":177,"targetDuration":4,"studyType":22,"phases":179,"briefSummary":180,"conditions":181,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":189,"leadSponsor":191,"locationsCount":45},"100601263","lateral-positioning-for-extubation-after-adenotonsillectomy-100601263","NCT07108218","Lateral Positioning for Extubation After Adenotonsillectomy","Lateral Positioning During the Anesthesia Emergence After Ambulatory Adenotonsillectomy in Children on Postoperative Respiratory Adverse Events: a Multi-center Randomized Controlled Trial","Inclusion criteria:\n\n1. Subjects aged 1-6 years old without gender limit.\n2. Scheduled for an ambulatory adenotonsillectomy under general anesthesia.\n3. American Society of Anesthesiologists (ASA) classification grade I or II.\n4. Informed consent obtained from the patients' parents or legal guardians, who have expressed willingness to cooperate.\n\nExclusion criteria:\n\n1. Presence of concomitant cardiac or pulmonary dysfunction or other significant systemic comorbidities.\n2. History of difficult airway management or congenital\u002Facquired structural anomalies of the airway.\n3. Active respiratory tract infection within 30 days preceding surgery.\n4. Preoperative neurological disorders or developmental abnormalities.\n5. Intraoperative occurrence of major complications necessitating deviation from the planned anesthesia protocol or surgical procedure.","6 Years",{"count":178,"type":21},350,[24],"The postoperative recovery period following general anesthesia has been associated with a 30%-50% incidence of postoperative respiratory adverse events (PRAEs) in pediatric populations, including laryngospasm, airway obstruction, and hypoxemia. Despite the limited effects of existing pharmacological and operative interventions, positional optimization (e.g., lateral or semirecumbent position) may play a potential role by decreasing airway resistance and improving oxygenation. However, evidence-based evidence for its use in pediatric populations is still lacking, necessitating the urgent need for randomized controlled trials.",[182,28,27,183],"Perioperative Respiratory Adverse Events","Children","2025-07-31",{"date":186,"type":37},"2025-08-06",{"date":188,"type":21},"2025-08-20",{"date":190,"type":21},"2026-08-27",{"name":192,"class":44},"Sichuan University",{"id":194,"slug":195,"hasResults":11,"nctId":196,"briefTitle":197,"officialTitle":198,"acronym":4,"eligibilityCriteria":199,"healthyVolunteers":11,"sex":16,"minAge":200,"maxAge":201,"enrollmentInfo":202,"targetDuration":4,"studyType":22,"phases":204,"briefSummary":205,"conditions":206,"keywords":209,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":211,"lastUpdatePostDateStruct":212,"startDateStruct":214,"completionDateStruct":215,"leadSponsor":217,"locationsCount":4},"100597754","etomidate-and-esketamine-on-postoperative-pain-after-tonsillectomy-undergoing-children-100597754","NCT07062601","Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children","Effect of Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children With General Anesthesia","Inclusion Criteria:\n\n* Children who underwent elective tonsillectomy\n* Aged 2-10 years old\n* ASA class I-II\n\nExclusion Criteria:\n\n* Children with hepatic or renal dysfunction\n* Those with increased intracranial or intra-ocular pressure\n* Children with schizophrenia, bipolar disorder, and any other psychiatric condition\n* Children with preexisting chronic pain\n* Children with preoperative combined sinus bradycardia or atrioventricular block","2 Years","10 Years",{"count":203,"type":21},64,[24],"Objective: To explore the effect of etomidate and esketamine on postoperative pain after tonsillectomy in children.\n\nMethods: Investigators enrolled 64 children with American Society of Anesthesiologists (ASA) physical status I and II, aged 2-10 years, and scheduled for elective undergoing tonsillectomy with general anesthesia. All the enrolled patients were randomly divided into etomidate and fentanyl group (Group A) and etomidate and esketamine group (Group B). In the etomidate-fentanyl group (group A), 0.3 mg\u002Fkg etomidate and 4 µg\u002Fkg fentanyl were given at the induction of anesthesia, followed by continuous infusion of propofol at 4-12 mg\u002Fkg\u002Fh and remifentanil at 3-6 µg\u002Fkg\u002Fh until the end of the surgery, respectively; in the etomidate-esketamine group (group B), induction of anesthesia with 0.3 mg\u002Fkg etomidate and 0.5 mg\u002Fkg esketamine , followed by continuous infusion of propofol at 4-12 mg\u002Fkg\u002Fh and remifentanil at 3-6 µg\u002Fkg\u002Fh until the end of the operation. Anesthesiologists who were unaware of the grouping recorded the FlACC Pain Scale at 2 h, 8 h, and 24 h after surgery.",[207,208,27,183],"Etomidate","Esketamine",[207,210,27],"Esketomine","2025-07-10",{"date":213,"type":37},"2025-07-14",{"date":211,"type":21},{"date":216,"type":21},"2025-11-15",{"name":218,"class":44},"Anqing Municipal Hospital",{"id":220,"slug":221,"hasResults":11,"nctId":222,"briefTitle":223,"officialTitle":223,"acronym":4,"eligibilityCriteria":224,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":225,"enrollmentInfo":226,"targetDuration":4,"studyType":22,"phases":228,"briefSummary":229,"conditions":230,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":4},"100574612","phase-3-comparsion-of-intravenous-injection-of-magnesium-sulfate-and-lidocaine-effectiveness-on-the-prevention-of-laryngospasm-and-analgesic-requirement-in-tonsillectomy-100574612","NCT06761547","Comparsion of Intravenous Injection of Magnesium Sulfate and Lidocaine Effectiveness on the Prevention of Laryngospasm and Analgesic Requirement in Tonsillectomy","Inclusion Criteria:\n\n* -ASA physical status I-II.\n* Both sexes.\n* Age: children 3-14years old.\n* patients subjected for tonsillectomy or adeno-tonsillectomy surgery with parental consent for participation in the study.\n\nExclusion Criteria:\n\n* \\- patients who refused to participate in this study.\n* History of allergic response to magnesium sulfate and liodcaine .\n* the Prescence of cardiovascular, respiratory and kidney diseases.\n* A recent history of upper respiratory tract infection and febrile illness.\n* History of mythenia gravis.\n* patients subjected for adeno-tonsillectomy with myringotomy","14 Years",{"count":227,"type":21},90,[150],"Tonsillectomy is one of the most common surgeries in children which is associated with many morbidities such as postoperative pain, nausea, vomiting, bleeding and laryngospasm .\n\nLaryngospasm is a dangerous complication of tonsillectomy that occurs following tracheal extubation It is characterized by a strong, involuntary contraction of the laryngeal muscles, it's frequency in children is higher than adults due to their narrow upper airways that can be blocked following edema and inflammation The incidence of laryngospasm is 17 per 1000 children younger than nine years old, which increases to 96 per 1000 children with upper respiratory tract infections There are several ways to prevent this complication, including complete haemostasis during surgery, gentle suctioning of the oropharynx before extubation and the use of drugs as intravenous or topical lidocaine, propofol and etc .\n\nPostoperative pain control after the tonsillectomy has a very important role in recovery time, hospitalization duration, bleeding, nausea and vomiting.\n\nLidocaine is an antiarrhythmic drug and its main mechanism of action is blocking voltage-gated Na+ channels that inhibit the activity of the upper laryngeal nerve and reduces the long-term blockage of the glottis .\n\nMagnesium sulphate has a calcium antagonist property, which provides muscle relaxation and increases flaccidity. It also has an antagonistic action on sodium channels and N-methyl-D-aspartate receptors and reduces the release of substance P, which decreases the airway reactivity and stress responses .\n\nTherefore we decided to compare the effect of intravenous injection of magnesium sulfate and lidocaine on the prevention of laryngospasm occurrence, and analgesic requirement in tonsillectomy the goal of the study Comparing the effectiveness of magnesium sulfate and lidocaine in prevention of post tonsillectomy complication .",[27],"2025-01-06",{"date":233,"type":37},"2025-01-07",{"date":235,"type":21},"2025-03-01",{"date":237,"type":21},"2027-03-01",{"name":239,"class":44},"Assiut University",{"id":241,"slug":242,"hasResults":11,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":246,"eligibilityCriteria":247,"healthyVolunteers":11,"sex":16,"minAge":200,"maxAge":201,"enrollmentInfo":248,"targetDuration":4,"studyType":22,"phases":250,"briefSummary":251,"conditions":252,"keywords":254,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":257,"lastUpdatePostDateStruct":258,"startDateStruct":260,"completionDateStruct":262,"leadSponsor":264,"locationsCount":45},"100474652","effectiveness-of-a-mhealth-application-as-a-family-supportive-tool-in-pediatric-otolaryngology-perioperative-process-100474652","NCT05460689","Effectiveness of a mHealth Application as a Family Supportive Tool in Pediatric Otolaryngology Perioperative Process","A Randomized Controlled Trial to Evaluate the Effectiveness of a mHealth Application as a Family Educational and Supportive Tool in Children Tonsillectomy and\u002For Adenoidectomy Perioperative Process Compared to Standard Care","TONAPP","Inclusion Criteria:\n\n* Caregivers of children aged 2-10 scheduled for tonsillectomy and\u002For adenoidectomy with or without tympanostomy tubes insertion;\n* Caregivers who are capable of oral and written communication without any impairment;\n* Caregivers who guarantee access to a smartphone and internet connection.\n\nExclusion Criteria:\n\n* Caregivers with cognitive deficits;\n* Caregivers of children with cognitive impairment\n* Caregivers with visual impairment;\n* Caregivers of children affected by chronic pain;\n* Caregivers of children who had another surgery operation in the previous month.\n* Caregivers who never used at least one smart phone application",{"count":249,"type":21},180,[24],"Tonsillectomy and\u002For adenoidectomy are common surgeries in children. Authors report how distressed children and their families are by perioperative processes. Fear of the unknown can put a strain on the preoperative period, while pain and other possible complications such as fever, vomiting, restricted oral feeding or bleeding can create difficulties in postoperative home management. Parental anxiety has been found to worsen the perception of pain, perioperative discomfort and recovery of operated children. Providing children and families with preparation for hospitalisation, surgery and postoperative home management has been shown to improve perioperative outcomes. However, not all individuals can understand and benefit from the information provided by healthcare professionals: higher levels of anxiety in the perioperative process have been associated with individuals with low health literacy. Furthermore, unmet information needs may lead parents to expose themselves to health-related misinformation through autonomous investigations on the Web and common social media resources. Patient- and family-centred education and support is a complex and time-consuming care practice, while some surgeries such as tonsillectomy are characterised by short hospitalisations that limit the amount of time health professionals can devote to this programme. Health systems have been testing different types of formats, content and ways of delivering health information\u002Feducation in order to meet the requirements of clients, time availability and effectiveness. MHealth apps in particular are an essential element of e-health and consist of medical information that is available via mobile phones or other wireless devices and can be used by patients or health professionals. Their use is growing and evolving into a variety of functionalities and positive outcomes related to improving the wellbeing of individuals, including diagnostics and clinical decision-making; interventions on healthy behaviours and lifestyles; patient disease management and self-care. Findings from literature highlight the need for further randomised controlled trials to confirm positive results.",[253],"TONSILLECTOMY",[255,27,256],"MHealth","Education","2024-06-12",{"date":259,"type":37},"2024-06-13",{"date":261,"type":37},"2022-12-16",{"date":263,"type":21},"2024-12-31",{"name":265,"class":44},"IRCCS Burlo Garofolo",{"id":267,"slug":268,"hasResults":11,"nctId":269,"briefTitle":270,"officialTitle":271,"acronym":4,"eligibilityCriteria":272,"healthyVolunteers":146,"sex":16,"minAge":53,"maxAge":18,"enrollmentInfo":273,"targetDuration":4,"studyType":22,"phases":275,"briefSummary":277,"conditions":278,"keywords":280,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":283,"lastUpdatePostDateStruct":284,"startDateStruct":286,"completionDateStruct":288,"leadSponsor":290,"locationsCount":45},"100333721","phase-4-gabapentin-premedication-to-reduce-postoperative-pain-for-pediatric-tonsillectomy-100333721","NCT03625011","Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy","Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy\u002FAdenoidectomy: Randomized Control Trial","Inclusion Criteria:\n\n* participants age 3-18 years\n* ASA class 1 or 2\n* elective Tonsillectomy\u002FAdenoidectomy\n* outpatient setting.\n\nExclusion Criteria:\n\n* BMI \\>40kg\u002Fm2\n* history of renal insufficiency, chronic pain\n* allergy to gabapentin\n* history of developmental delay",{"count":274,"type":21},50,[276],"PHASE4","The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg\u002Fkg given 2) to record the time to first analgesic postoperatively and 3) to compare Wong Baker and the 0-10 numeric pain distress scale scores at 12, 24 and 48 hours postoperatively. We hypothesize one 15mg\u002Fkg (up to 600mg) dose of gabapentin will decrease mean narcotic amounts in mg\u002Fkg compared to participants who do not receive preoperative gabapentin and will demonstrate a decreased mean time to first analgesic as well as to lower mean pain scores for each age group at 12, 24 and 48 hours.",[279,27],"Tonsillitis",[281,282],"Pain Relief","Non-Narcotic Pain relief","2019-07-23",{"date":285,"type":37},"2019-07-24",{"date":287,"type":37},"2018-07-31",{"date":289,"type":21},"2019-12-31",{"name":291,"class":44},"Children's Healthcare of Atlanta"]