[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tonsillitis-recurrent\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tonsillitis-recurrent":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100595658","the-effect-of-systemic-nonsteroidal-anti-inflammatory-drugs-nsaids-vs-intraoperative-infiltration-of-steroids-in-tonsillar-bed-following-tonsillectomy-on-post-tonsillectomy-pain-100595658",false,"NCT07035314","The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain.","The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain: A Prospective Randomized Controlled Study.","NSAIDs","Inclusion Criteria:\n\n* Age: Between 4-10 years.\n* Indications of tonsillectomy such as:\n\n  * Recurrent acute attacks at least 7 episodes in the past year or at least 5 episodes per year for 2 years or at least 3 episodes per year for 3 years.\n  * Chronic tonsillitis and hypertrophy of tonsils causing sleep apnea, difficulty in deglutition, interference in speech.\n* Tonsillectomy by cold dissection only.\n* American Society of Anesthesiologists (ASA) classification 1,2 (Normal Health, Mild systematic disease).\n\nExclusion Criteria:\n\n* Patients with age less than 4 and more than 10 years.\n* Indications of tonsillectomy other than chronic tonsillitis such as lymphoma.\n* Patients on chronic steroid therapy\n* Hemoglobin level less than 10 gm\u002FdL\n* Presence of acute infection in the upper respiratory tract, acute tonsillitis\n* American Society of Anesthesiologists (ASA) classification ASA 3,4 (Severe systematic disease such as uncontrolled Diabetes, cardiac disease, liver or kidney disease, life threating medical conditions)\n* Regular use of analgesics within a week of surgery.","ALL","4 Years","10 Years",{"count":21,"type":22},75,"ESTIMATED","INTERVENTIONAL",[25],"NA","The aim of this study is to compare the efficacy of adding paracetamol to systemic non-steroidal anti-inflammatory drugs (NSAIDs) versus adding dexamethasone as local infiltration to paracetamol on post tonsillectomy pain control.",[28,29,30],"Tonsillitis Chronic","Tonsillitis Recurrent","OSA - Obstructive Sleep Apnea",[32,33,34,35,15],"tonsillitis","tonsillectomy","post tonsillectomy pain","Dexamethasone infiltration in tonsillar bed","RECRUITING","2025-06-15",{"date":39,"type":40},"2025-06-25","ACTUAL",{"date":42,"type":40},"2025-03-08",{"date":44,"type":22},"2025-08-01",{"name":46,"class":47},"Ain Shams University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":62,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":5},"100562676","tonsillectomy-versus-tonsillotomy-in-the-treatment-of-recurrent-acute-tonsillitis-100562676","NCT06606262","Tonsillectomy Versus Tonsillotomy in the Treatment of Recurrent Acute Tonsillitis","Tonsillectomy Versus Tonsillotomy in the Treatment of Recurrent Acute Tonsillitis: A Randomized Controlled Non-inferiority Trial","Inclusion Criteria:\n\n* Adults (age ≥15 years) with RT, defined as a minimum of five tonsillitis episodes in one year or a minimum of three tonsillitis episodes per year for two years (Danish National Guidelines criteria\n* The ability to understand Danish orally and in writing.\n\nExclusion Criteria:\n\n* Previous TE or TO.\n* Suspected tonsillar malignancy.\n* History of malignant tumor in the oral cavity, the pharynx or the larynx.\n* Previous radiation therapy on head or neck.\n* Hemorrhagic diathesis or anticoagulant therapy.","15 Years",{"count":58,"type":22},250,[25],"Background: recurrent acute tonsillitis (RT) is a frequent condition affecting teenagers and adults. Patients suffer from recurring throat symptoms, fever and impaired quality of life (QOL). Tonsillectomy (TE) is the only well-known treatment, but studies indicate that tonsillotomy (TO) is associated with less morbidity (eg. pain and bleeding) and equal efficiency (e.g. reduced number of sore throat episodes and improved QOL). The investigator aim to clarify whether TO is a non-inferior alternative to TE.\n\nMethods: inclusion and randomization of 250 adult RT patients for TE or TO with a 12 month follow up. Comparisons will be made between groups, and outcome measures includes number of sore throat episodes, QOL and postoperative pain.\n\nDiscussion: the study has the potential to improve the treatment of a prevalent disease by enhancing knowledge of an alternative procedure (TO) associated with less discomfort and risk than the current standard procedure (TE) and a presumably low risk of insufficiency.",[29],[33,63,64],"tonsillotomy","quality of life","2024-12-17",{"date":67,"type":40},"2024-12-19",{"date":69,"type":40},"2024-10-31",{"date":71,"type":22},"2029-12-31",{"name":73,"class":47},"Tejs Ehlers Klug"]