[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tooth-extraction-status-nos\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tooth-extraction-status-nos":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,47,85,112,141,175],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100627528","assessment-of-labial-plate-thickness-after-immediate-implant-placement-using-two-different-xenografts-in-the-esthetic-zone-100627528",false,"NCT07449806","Assessment of Labial Plate Thickness After Immediate Implant Placement Using Two Different Xenografts in the Esthetic Zone","Assessment of Labial Plate Thickness After Immediate Implant Placement in Type II Extraction Sockets Using Two Different Xenografts in the Esthetic Zone: a Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Patients with one or more non-restorable teeth or remaining roots without signs of acute infection in the maxillary anterior region.\n* Type II extraction sockets.\n* Sufficient bone (\\>3 mm) apically and palatally to allow for proper implant positioning with sufficient primary stability (≥ 30 N cm).\n* Good compliance.\n\nExclusion Criteria:\n\n* Teeth with current acute periapical infection.\n* Medically compromised patients.\n* Heavy smokers (smoking of more than 10 cigarettes per day ).\n* Alcohol or drug abuse.\n* Patients undergoing chemotherapy and radiotherapy.\n* Poor oral hygiene.\n* Vulnerable groups (pregnant females and decision- impaired individual).","ALL",{"count":18,"type":19},26,"ESTIMATED","INTERVENTIONAL",[22],"NA","This randomized clinical trial aims to evaluate labial bone plate changes following immediate implant placement in Type II extraction sockets using two different xenograft materials and de-epithelialized free gingival graft in the esthetic zone . Patients requiring extraction and immediate implant placement will be randomly allocated into two groups according to the xenograft material used for defect grafting. Clinical and radiographic outcomes will be assessed to determine dimensional bone changes and implant success",[25,26,27],"Alveolar Bone Loss","Tooth Extraction Status Nos","Immediate Implant Placement",[29,30,31,32,33],"immediate implant placement","type II extraction socket","esthetic zone.","xenograft","randomized controlled clinical trial","RECRUITING","2026-03-04",{"date":37,"type":38},"2026-03-06","ACTUAL",{"date":40,"type":38},"2025-09-05",{"date":42,"type":19},"2026-09-25",{"name":44,"class":45},"Basma Gamal Mohamed Ahmed","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":16,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":20,"phases":60,"briefSummary":61,"conditions":62,"keywords":68,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":46},"100575923","comparison-of-piezoelectric-and-conventional-surgery-for-germectomy-of-the-lower-third-molar-100575923","NCT06778590","Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar","Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar: Assessment of Post-operative Sequelae","Germectomy","Inclusion Criteria:\n\n* Patients aged between 14 and 24 years, with both lower third molars in the developmental stage (with incompletely formed roots) and requiring extraction of both for prophylactic, therapeutic or strategic reasons\n* Good quality of radiographic investigations (CBCT)\n* Good health status",true,"14 Years","24 Years",{"count":59,"type":19},22,[22],"The main objective of the study is to compare the effects of the piezoelectric surgery and the traditional technique on soft tissue edema in patients undergoing bilateral germectomy of mandibular third molars",[63,64,65,26,66,67,53],"Tooth Disease","Piezoelectric Technique","Tooth Impacted","Tooth Avulsion","Facial Swelling",[69,70,71,72,73,74,75],"third molar surgery","facial swelling","3D facial swelling evaluation","Piezoelectric technique","tooth impacted","piezosurgery","germectomy","2025-01-15",{"date":78,"type":38},"2025-01-16",{"date":80,"type":38},"2024-08-01",{"date":82,"type":19},"2025-10-31",{"name":84,"class":45},"Amerigo Giudice",{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":55,"sex":16,"minAge":92,"maxAge":4,"enrollmentInfo":93,"targetDuration":4,"studyType":20,"phases":95,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":46},"100564748","adjunctive-use-of-polynucleotide-and-hyaluronic-acid-based-gel-in-alveolar-preservation-after-tooth-extraction-100564748","NCT06633211","Adjunctive Use of Polynucleotide and Hyaluronic Acid-based Gel in Alveolar Preservation After Tooth Extraction","Clinical and Histological Effects of the Adjunctive Use of Polynucleotide and Hyaluronic Acid-based Gel in Alveolar Preservation After Tooth Extraction: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Adults (\\>18 years) who need the extraction of a single non-molar tooth in the mandible or maxilla.\n* ASA I or II\n* Intact post-extraction socket or with only one wall dehiscence (buccal or lingual) of no more than 50% of the socket.\n* The treatment plan must include the replacement of the tooth to be extracted by placing an implant and an implant-supported prosthesis.\n\nExclusion Criteria:\n\n* Mandibular incisors and molars.\n* Acute infection associated with the tooth that needs to be extracted.\n* Uncontrolled systemic disease.\n* Pregnant patient.\n* Patient under treatment with antiresorptives drugs (bisphosphonates or Receptor Activator of Nuclear Factor Kappa-B Ligand (i.e., Denosumab)) or antiangiogenics.\n* Smokers (\\>10 cigarettes a day).","18 Years",{"count":94,"type":19},20,[22],"Alveolar ridge resorption after tooth extraction is a physiological process that continues throughout the patient's life due to the loss of the periodontal ligament and lack of mechanical stimulation. Alveolar ridge preservation (ARP) techniques aim to minimize dimensional changes in the ridge after tooth extraction. These techniques involve grafting the socket to fill the bed and\u002For sealing it with a biomaterial. Currently, there is a polynucleotide and hyaluronic acid-based gel (Regenfast®) on the market that has proven useful in treating residual periodontal defects. Hyaluronic acid-based gels also appear to enhance the regenerative potential of critical bone defects in both in-vitro studies on rats and clinical studies. Therefore, this study aims to evaluate the clinical and histological effects of polynucleotide and hyaluronic acid-based gel in alveolar preservation procedures.",[98,26],"Bone Substitutes",[100,101],"Alveolar Ridge preservation","Guided bone regeneration","NOT_YET_RECRUITING","2024-10-07",{"date":105,"type":38},"2024-10-09",{"date":107,"type":19},"2024-10-15",{"date":109,"type":19},"2025-10-15",{"name":111,"class":45},"Adrià Jorba García",{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":4,"eligibilityCriteria":118,"healthyVolunteers":55,"sex":16,"minAge":92,"maxAge":119,"enrollmentInfo":120,"targetDuration":4,"studyType":20,"phases":122,"briefSummary":123,"conditions":124,"keywords":127,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":46},"100457731","pontic-shield-technique-in-alveolar-ridge-preservation-100457731","NCT05240417","\"Pontic-shield\" Technique in Alveolar Ridge Preservation","Effectiveness of \"Pontic-shield\" Technique in Alveolar Ridge Preservation: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patient from 18 to 80 years old\n* Patients who sign the informed consent\n* Need to perform extraction from second premolar to second premolar in maxilla and mandible\n\nExclusion Criteria:\n\n* Tobacco consumption (more than 10 cigarettes per day)\n* Severe systemic disease ( ASA III or IV - American Society of Anaesthesiology)\n* Drug use that could interfere with alveolar bone healing\n* Active periodontal disease\n* Acute or chronic apical pathology of the tooth","80 Years",{"count":121,"type":19},30,[22],"Alveolar bone resorption after dental extraction frequently leads to situations in which long-term function and esthetic success of rehabilitations with dental implants is a challenge. \"Pontic-shield\" has been described as an alternative technique to maintain alveolar ridge after tooth extraction.\n\nThe aim of this study is to analyze the effectiveness of \"Pontic-shield\" technique in alveolar ridge preservation comparing to fresh socket and ridge preservation using deproteinized bovine bone and a porcine collagen membrane.",[26,125,126],"Bone Loss","Bone Resorption",[128,129,130,131],"Tooth extraction","Alveolar ridge preservation","Partial extraction therapies","Bone resorption","2024-08-19",{"date":134,"type":38},"2024-08-20",{"date":136,"type":38},"2023-01-01",{"date":138,"type":19},"2024-12-01",{"name":140,"class":45},"Universidad Complutense de Madrid",{"id":142,"slug":143,"hasResults":11,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":147,"eligibilityCriteria":148,"healthyVolunteers":55,"sex":16,"minAge":92,"maxAge":4,"enrollmentInfo":149,"targetDuration":4,"studyType":20,"phases":151,"briefSummary":152,"conditions":153,"keywords":157,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":46},"100390733","management-of-the-fresh-extraction-socket-in-the-aesthetic-area-100390733","NCT04367766","Management of the Fresh Extraction Socket in the Aesthetic Area","Management of the Fresh Extraction Socket in the Aesthetic Area: Alveolar Ridge Preservation vs Immediate Implant Placement vs Delayed Implant Placement","IIP\u002FARP\u002FSH","Inclusion Criteria:\n\n* single tooth extraction in the anterior region of the dentition (including premolars) to be extracted\n* smoking no more than 10 cigarettes\u002Fday,\n* periodontal health (BoP \\\u003C 10%) and good plaque control (\\\u003C 20%)\n* absence of symptomatic periapical radiolucencies, acute abscesses at the site of extraction,\n* extraction sites with less than 30% loss of one or more walls\n* adequate quantity and quality of native bone to achieve primary stability\n\nExclusion Criteria:\n\n* growing patients\n* patients with autoimmune disease, uncontrolled diabetes or immunocompromised\n* history of head and neck radiation for cancer treatment,\n* pregnancy",{"count":150,"type":19},60,[22],"After atraumatic tooth extraction and the assessment of the feasibility of immediate implant placement, patients will be randomly assigned to one of three treatment concepts:\n\n1. Immediate Implant Placement and Immediate Provisionalization\n2. Alveolar Ridge Preservation. After 4 months of healing an implant will be placed with simultaneous GBR and\u002For Soft Tissue Augmentation procedures, if needed.\n3. Spontaneous Healing of the socket. After 4 months of healing, an implant will be placedwith simultaneous GBR and\u002For Soft Tissue Augmentation procedures, if needed.\n\nIn all groups, four months after implant placement, a prosthesis will be delivered. From this experimental period onward, patients will be scheduled for maintenance. Clinical, radiographic and volumetric assessment will be performed by clinicians not involved in the surgery and blind with respect to treatment assignment at 1, 3 and 5 years post loading.",[26,154,155,156],"Dental Implant","Bone Augmentation","Soft Tissue Augmentation",[158,159,160,161,162,163,164],"Immediate implant placement","alveolar ridge preservation","delayed implant placement","PROMs","implant health","volumetric analysis","tissue augmentation","2023-12-06",{"date":167,"type":38},"2023-12-12",{"date":169,"type":38},"2023-09-27",{"date":171,"type":19},"2026-08",{"name":173,"class":174},"Centro Specialistico Odontoiatrico, Rome","NETWORK",{"id":176,"slug":177,"hasResults":11,"nctId":178,"briefTitle":179,"officialTitle":180,"acronym":181,"eligibilityCriteria":182,"healthyVolunteers":55,"sex":16,"minAge":92,"maxAge":4,"enrollmentInfo":183,"targetDuration":4,"studyType":20,"phases":185,"briefSummary":186,"conditions":187,"keywords":4,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":188,"lastUpdatePostDateStruct":189,"startDateStruct":191,"completionDateStruct":193,"leadSponsor":195,"locationsCount":4},"100527403","effect-alb-prf--a-prf-in-alveolar-ridge-preservation-in-diabetes-patients---a-rcct-100527403","NCT06147310","Effect Alb-PRF & A-PRF in Alveolar Ridge Preservation in Diabetes Patients - A RCCT","Effect of Albumin Gel-platelet-rich Fibrin (Alb-PRF) and Advanced Platelet-rich Fibrin (A-PRF) in Alveolar Ridge Preservation in Diabetes Patients - A Randomized Controlled Clinical Trial","AlbPRFARP","i. At least 18 years old with established TIIDM diagnosis for more than 0.5 years, fasting blood glucose ≥7.0 mmol\u002FL or 2 h plasma glucose ≥11.1 mmol\u002FL, maximum HbA1c levels under 8.0%.\n\nii. Non-smoker, diagnosed with generalized periodontitis stage III or IV. iii. Need for extraction of teeth, on opposing arches or opposing sides, with or without other concurrent indications for extractions: orthodontics, periodontitis, caries, fracture, root resorption, unrestorable root fragments.\n\niv. At least one adjacent teeth\u002F implant is present at the site of extraction with a secure prognosis.\n\nv. No periapical lesions with a diameter of more than 5 mm (radiographically determined.\n\nvi. Extraction socket with a bone height of at least 7mm at 2 walls. vii. Reasonably aligned dental arches viii. Will consider implant to replace missing teeth ix. Willing and able to give informed consent.\n\nExclusion Criteria:\n\ni. Patients with conditions or circumstances, in the opinion of the Investigator, which would prevent completion of study participation or interfere with analysis of study results, such as history of non-compliance or unreliability.\n\nii. Pregnancy or intention to become pregnant at any point during the study duration.\n\niii. Smoker \u002Falcoholic iv. Has platelet dysfunction\u002F thrombocytopenia\u002F blood dyscrasia v. On bisphosphonates or drugs that will significantly alter bone metabolism. vi. ASA III\u002FIV.",{"count":184,"type":19},74,[22],"This study aim to investigate the effect of albumin gel- and platelet- rich fibrin(Alb-PRF) combined with advanced platelet-rich fibrin (A-PRF) on alveolar ridge preservation by comparing alveolar ridge morphometric changes (hard and soft tissue), prospects and treatment complexity for placement of prosthetically guided dental implant, early oral wound healing outcomes evaluated by the Inflammatory Proliferative Remodeling Scale, and patient reported outcome measures, in Type I\u002FII Diabetes Mellitus patient, versus spontaneous healing",[26],"2023-11-24",{"date":190,"type":38},"2023-11-29",{"date":192,"type":19},"2024-09-01",{"date":194,"type":19},"2026-06-30",{"name":196,"class":45},"The University of Hong Kong"]