[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tooth-loss--rehabilitation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tooth-loss--rehabilitation":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,78,105],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100639363","3d-printed-versus-band-and-loop-versus-denovo-space-maintainers-in-primary-dentition-100639363",false,"NCT07613658","3D-Printed Versus Band-and-Loop Versus Denovo Space Maintainers in Primary Dentition.","3D-Printed Custom Versus Conventional Band-and-Loop Versus Chairside Denovo Space Maintainers in the Primary Dentition: A Randomized Controlled Trial Protocol","Inclusion Criteria:\n\n1. Children aged 5 to 10 years\n2. Premature unilateral loss of at least one primary first or second molar\n3. Radiographically confirmed developing permanent successor at Nolla developmental stage 4 to 7\n4. Parent or legal guardian able and willing to provide written informed consent, and child able to provide age-appropriate assent\n\nExclusion Criteria:\n\n1. Systemic disease affecting bone metabolism or tooth development\n2. Clinically significant mesiodistal space loss at screening, defined as greater than 3 mm\n3. Poor oral hygiene precluding band placement, defined as a full-mouth plaque score greater than 50%\n4. Known allergy or hypersensitivity to stainless steel or resin components\n5. Current participation in another interventional clinical trial",true,"ALL","5 Years","10 Years",{"count":21,"type":22},360,"ESTIMATED","INTERVENTIONAL",[25],"NA","Purpose of the Study When a child loses a \"baby\" molar early due to a cavity or injury, the surrounding teeth can shift into the empty space. This often blocks the permanent adult tooth from growing in correctly. To prevent this, dentists use a small metal device called a space maintainer.\n\nThis study aims to find out which of three different types of space maintainers lasts the longest, is most comfortable for the child, and is most efficient for the dental office to provide.\n\nThe Three Study Groups\n\nChildren in this study are randomly assigned to one of three groups:\n\n1. 3D-Printed Custom Group: The dentist takes a digital picture (scan) of the child's mouth instead of a traditional mold. A custom-fit appliance is then 3D-printed using a specialized, medical-grade clear material.\n2. Conventional Band-and-Loop Group: This is the traditional method. The dentist takes a physical mold of the teeth, which is sent to a laboratory. The child usually has to return for a second appointment a week later to have the metal appliance glued into place.\n3. Denovo Chairside Group: This uses a kit of pre-made metal parts. The dentist selects the best fit and assembles the appliance right at the chairside, allowing it to be placed during a single visit.\n\nWhat is Being Measured?\n\nResearchers are following the children for 12 months to track:\n\nSurvival: Which appliance stays glued in and doesn't break most effectively?\n\nTime: How much time does the dentist spend making and fitting the appliance?\n\nComfort: How much discomfort or pain did the child feel during the process?\n\nHealth: Does the appliance cause any irritation to the gums or surrounding teeth?\n\nWho Can Participate? The study includes children between the ages of 5 and 10 who have lost at least one primary (baby) molar early and need a space maintainer to protect their future adult smile.\n\nImportance of This Research By comparing these three methods, this study helps dentists understand if newer technologies, like 3D printing or pre-made kits, are better or more convenient than the traditional lab-made metal loops used for decades. This information will help families choose the best treatment for their children.",[28,29],"Space Maintenance","Tooth Loss \u002F Rehabilitation",[28,31,32,33],"Band and Loop","3D-Printed Space Maintainer","Denovo Space Maintainer","NOT_YET_RECRUITING","2026-05-21",{"date":37,"type":38},"2026-05-29","ACTUAL",{"date":40,"type":22},"2026-06",{"date":42,"type":22},"2027-07",{"name":44,"class":45},"Murad Alrashidi","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":46},"100630085","influence-of-vertical-implant-position-on-marginal-bone-loss-in-cases-with-thin-phenotype-100630085","NCT07483086","Influence of Vertical Implant Position on Marginal Bone Loss in Cases With Thin Phenotype","The Influence of Vertical Implant Position With Immediate Temporization on Marginal Bone Loss in Cases With Thin Soft Tissue Phenotype: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Patients with single missing upper anterior or premolar teeth\n* Patients with minimum buccolingual width of 6 mm and mesiodistal width of 6 mm\n* Patients with thin soft tissue phenotype\n* Patients with healthy systemic conditions.\n* Patients older than 18 years.\n* Good oral hygiene.\n* Cooperative patients who accept a one-year follow-up period.\n* Patients who consent to being part of the study (sign an informed consent form).\n* Adequate inter-arch space for implant placement.\n* Favorable occlusion (no traumatic occlusion).\n* Absence of allergy to the prescribed medications.\n\nExclusion Criteria:\n\n* Patients with inadequate bone volume and\u002F or quality\n* Patients with local root remnants\n* Patients with inadequate wound healing\n* Patients with signs of acute infection related to the area of interest.\n* Patients with habits that may jeopardize the implant longevity and affect the results of the study such as parafunctional habits (Lobbezoo et al., 2006).\n* Heavy smokers (more than 10 cigarettes per day) (Lambert, Morris and Ochi, 2000).\n* Metabolic diseases such as diabetes or hyperthyroidism as well as systemic medications such as chemotherapy or bisphosphonates\n* Pregnant or nursing women.\n* Uncooperative patients.","18 Years",{"count":56,"type":22},30,[25],"The goal of this clinical trial is to learn if vertical position of the dental implant will affect the bone around the implant in place of a missing tooth that happens to be bounded by two natural teeth. It will also measure esthetics and patient satisfaction. The main questions it aims to answer are:\n\nDoes vertical implant position below the crest of the bone lead to less marginal bone loss? Will it affect implant survival as well as quality of soft tissue, esthetics and patient satisfaction?\n\nParticipants will:\n\nHave an implant placed at the bone level or 2 mm below the bone level Visit the clinic once every 3 months for checkups, radiographs, and readings",[60,61,29],"Vertical Implant Position","Delayed Implant Placement With Immediate Loading",[63,64,65,66,67],"Vertical position","subcrestal","crestal","delayed implant placement with immediate loading","vertical dental implant position","RECRUITING","2026-03-29",{"date":71,"type":38},"2026-04-02",{"date":73,"type":38},"2025-01-16",{"date":75,"type":22},"2027-02",{"name":77,"class":45},"Cairo University",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":16,"sex":17,"minAge":54,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":23,"phases":87,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":46},"100617206","in-vivo-evaluation-of-the-accuracy-of-immediate-screw-retained-provisional-crowns-fabricated-using-digital-planning-and-guided-surgery-100617206","NCT07315607","In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Fabricated Using Digital Planning and Guided Surgery","In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Prefabricated Using Digital Planning and Fully Guided Surgery","Inclusion Criteria:\n\n1. Adults aged 18 years or older.\n2. Partially edentulous patients requiring replacement of a single tooth with an immediately loaded dental implant.\n3. Patients classified as ASA I or ASA II according to the American Society of Anesthesiologists physical status classification.\n4. Patients with clinical conditions allowing immediate implant placement with a minimum primary stability of ≥25 Ncm.\n5. Ability to understand the study procedures and provide written informed consent.\n6. Willingness to comply with the study protocol and attend required clinical visits.\n\nExclusion Criteria:\n\n1. Patients classified as ASA III or ASA IV, or with uncontrolled systemic conditions that may interfere with study participation.\n2. Presence of psychiatric or cognitive disorders that may compromise informed consent or protocol compliance.\n3. Inability to comply with the visit schedule or required evaluations.\n4. Any other condition that, in the investigator's judgment, could compromise patient safety, protocol adherence, or data validity.",{"count":86,"type":22},27,[25],"This clinical trial aims to evaluate the in vivo accuracy of a fully digital workflow for the immediate placement of a previously fabricated screw-retained provisional crown using digital planning and guided implant surgery. The study will be conducted in partially edentulous adult patients requiring the replacement of a single tooth with an immediately loaded dental implant.\n\nThe main objective of the study is to assess the accuracy (trueness and precision) of the planned digital implant position and provisional restoration by comparing the virtually planned position with the actual clinical outcome after guided surgery. Emphasis will be placed on linear, angular, and rotational deviations at both the implant and provisional restoration levels.\n\nParticipants will undergo a fully guided implant placement procedure with rotational control, followed by the immediate placement of a prefabricated screw-retained provisional crown designed during the digital planning phase. Postoperative intraoral scans will be obtained to register the final implant and restoration positions.\n\nThe planned and achieved positions will be compared using three-dimensional analysis software to quantify deviations and determine whether the accuracy achieved remains within clinically acceptable limits.",[90,29],"Partial Edentulism",[92,93,94,95],"Immediate provisionalization","Screw-retained provisional crown","Guided implant surgery","Digital implant planning","2026-01-08",{"date":98,"type":38},"2026-01-09",{"date":100,"type":22},"2026-01",{"date":102,"type":22},"2027-01",{"name":104,"class":45},"Universidad Complutense de Madrid",{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":111,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":113,"enrollmentInfo":114,"targetDuration":116,"studyType":117,"phases":4,"briefSummary":118,"conditions":119,"keywords":120,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":46},"100618856","dental-implant-set-development-and-implementation-of-a-standardized-outcome-set-in-implant-dentistry-100618856","NCT07337057","DEntal implaNt Set: Development and Implementation of a Standardized Outcome Set in Implant Dentistry","PROMs in Implant Dentistry: Development of a Dental Implant Standard Set","DENS","Inclusion Criteria:\n\n* Age 18-70 years\n* Indication for implant-supported fixed single or multiple tooth replacement\n* Indication for implant-supported removable prosthesis\n* Immediate implant placement cases\n* Implant placement after implant failure\n\nExclusion Criteria:\n\n* Inadequate oral hygiene\n* Physical inability\n* Pregnancy\n* History of radiotherapy in head and neck region\n* Language barriers\n* Patients requiring soft tissue grafts prior to dental implant placement\n* Patients requiring bone augmentation with harvesting autogenous bone from intraoral sites prior to dental implant placement","75 Years",{"count":115,"type":22},1000,"18 Months","OBSERVATIONAL","Rationale Over the past decades, the placement of dental implants and prosthetic rehabilitation has revolutionised dentistry overwhelmingly. It is generally regarded as a safe and reliable method due to the high predictability and survival rates. Survival of suprastructure and implant, health status of the peri-implant tissues and radiographic peri-implant marginal bone loss are commonly used criteria to assess the implant treatment outcome. Although this way of treatment evaluation is important to develop and deliver safe dental implants, it does not provide sufficient information for the development of value-based healthcare.\n\nWith this new approach of health outcome measurement, in which patient reported outcomes and clinical outcomes are combined, new definitions of success are created that transform dental implant health care by informed decision making, quality improvement and reducing costs. If dentists and oral surgeons make treatment decisions based on this comprehensive health outcome, patients are more likely to receive high quality care and payers only pay for services that achieve results. Therefore, the development of an implant dentistry specific question set, a Dental Implant Standard Set, capturing both the clinicians' and patients' perspective of implant-related health outcomes is of utmost clinical relevance.\n\nObjective(s) A combination of patient-reported outcomes and clinical health outcomes in a Dental Implant Standard Set enables clinicians to evaluate care delivery and to compare performance in a comprehensive and meaningful way. Therefore, the main aim for this project is to implement a workable Dental Implant Standard Set for the dental implant professional to monitor and improve clinicians and patients' perception of peri-implant health following dental implant treatment, and to monitor and improve the performance of dental implant practice as a whole.\n\nStudy type This is a prospectively designed multicenter cohort study including 30 dental practices in the Netherlands and Spain\n\nStudy population A total of 1000 consecutive patients will be included by the participating dental practices within 12 months.\n\nQuestionnaires regarding the clinical outcomes are administered to the dentists providing the dental implant care. PROMs are administered to the participating patients.\n\nGenerally, patients aged 18-70 years that have an indication for implant supported fixed single or multiple tooth replacement or implant-supported removable prosthesis are eligible to participate.\n\nMethods the questionnaires are administered to the participating dentist (for clinical outcomes) and patients (Patient Reported Outcome Measures (PROMs) in combination with the collection of clinical and case mix variables at 6 time points: before and at implant placement, at prosthesis placement and 10-12 months after implant placement. The PROMs is administered via a Questionnaire Manager (QM), that is developed by an external company. Within the QM also case mix and clinical data are registered\n\nBurden and risks No risks are involved throughout the study The concise questionnaires to the patients and participating dentist will be a limited burden to the standard dental implant care.\n\nRecruitment and consent Treating clinicians will recruit participants for this project. Clinicians will provide the patient with a brief overview of the study. Participants will receive a digital questionnaire via a link with an informed consent form and contact details (of the principal investigator) for remaining questions.\n\nData is not open accessible and patient specific data will be anonymously stored.",[29],[121,122,123,124,125],"Dental implants","Patient reported outcome measures","Core outcome set","Implant dentistry","Peri-implant health","2026-01-06",{"date":128,"type":38},"2026-01-13",{"date":130,"type":38},"2024-06-24",{"date":132,"type":22},"2027-06-01",{"name":134,"class":45},"Erasmus Medical Center"]