[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"toothbrushing\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:toothbrushing":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100616662","clinical-microbiological-and-compliance-outcomes-of-ai-based-toothbrushes-in-plaque-induced-gingivitis-100616662",false,"NCT07308522","Clinical ,Microbiological and Compliance Outcomes of AI-based Toothbrushes in Plaque Induced Gingivitis","Clinical ,Microbiological and Compliance Outcomes of AI-based vs Standard Electric and Manual Toothbrushes in Adults With Plaque-Induced Gingivitis: A 6-Week Randomized Controlled Trial","Inclusion Criteria:\n\n* Participants should be systemically healthy\n* 18 years old, with the presence of ≥ 20 teeth\n* Diagnosed with generalized plaque-induced gingivitis having \\>30% bleeding sites, with probing depths ≤3 mm and intact periodontium\n* Participants with at least secondary school education, who are able to read and understand basic English to follow the app-based toothbrush instructions\n\nExclusion Criteria:\n\n* Participants who using antibiotics or anti-inflammatory medication throughout the investigation or during the previous 3 months prior to the study.\n* Drug-induced gingival enlargement (phenytoin, cyclosporine, calciumchannel blockers).\n* Individuals with periodontitis and healthy periodontium.\n* Mouth breathers .\n* Individuals with severe dental crowding or malalignment that prevents proper toothbrushing.\n* Individuals with heavy calculus.\n* Individuals who smoke or alcoholism.\n* Pregnant, breastfeeding women or those using contraceptive tablets.\n* Individuals with orthodontic devices or removable dentures","ALL","18 Years","35 Years",{"count":20,"type":21},33,"ESTIMATED","INTERVENTIONAL",[24],"NA","Severe periodontitis is widespread and begins with reversible gingivitis, driven by poor oral hygiene and a dysbiotic microbiome. Daily toothbrushing is the simplest prevention, but patients still leave plaque. Electric brushes remove more plaque and reduce gingivitis better than manual ones, and users show better periodontal status. App-connected smart brushes and apps aim to improve adherence. Trials increased plaque reduction and brushing time versus manual brushing, but app layers have not clearly beaten standard power brushes, and microbiological outcomes are rarely reported. Xiaomi's AI-based sonic T501 adds pressure sensing, personalised coaching and coverage tracking, whereas the T302 is a simpler non-connected sonic brush. Streptococcus sanguinis is a health-associated early coloniser; its qPCR-measured relative abundance marks a healthy supragingival profile. It is still unclear whether AI guidance adds extra benefit beyond a standard electric brush in adult gingivitis.",[27,28,29],"Plaque Induced Gingivitis","Toothbrushing","Compliance","NOT_YET_RECRUITING","2025-12-13",{"date":33,"type":34},"2025-12-29","ACTUAL",{"date":36,"type":21},"2026-01-01",{"date":38,"type":21},"2026-06-30",{"name":40,"class":41},"University of Baghdad","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":42},"100595256","evaluation-of-a-novel-dual-headed-toothbrush-design-for-periodontal-health-split-mouth-randomized-blind-clinical-trial-100595256","NCT07030088","Evaluation of a Novel Dual-Headed Toothbrush Design for Periodontal Health: Split-Mouth Randomized Blind Clinical Trial","Clinical and Patient-Based Evaluation of a Novel Dual-Headed Toothbrush Design: Split-Mouth Clinical Trial","Inclusion Criteria:\n\n* • Dentists with a minimum of 26 natural teeth, good general health, and the ability to perform routine oral hygiene independently.\n\n  * No systemic diseases affecting oral hygiene.\n  * Record of mild-to-moderate plaque accumulation; PI score ≥ 1\n  * Rt handed dentists\n\nExclusion Criteria:\n\n* • Participants with active periodontal disease, orthodontic appliances, or having recent oral surgery\n\n  * Those currently enrolled in any other dental trial\n  * Smokers.","25 Years","40 Years",{"count":53,"type":21},40,[24],"The goal of this clinical trial is to evaluate the effectiveness and patient satisfaction of a novel dual-headed toothbrush design compared to a conventional single-headed toothbrush in adult dental professionals aged 22-45 years with healthy gingival conditions. The main questions it aims to answer are:\n\nDoes the dual-headed toothbrush improve plaque removal efficiency compared to a single-headed toothbrush? Does the dual-headed toothbrush enhance brushing comfort, reduce brushing time, and improve user satisfaction? Researchers will compare the side of the mouth (cleaned with a dual-headed toothbrush) with the other side (cleaned with a single-headed toothbrush) in a randomized split-mouth design to see if the novel design leads to superior plaque control and better user experience.\n\nParticipants will:\n\nReceive both toothbrush types (medium bristle) and identical toothpaste Be trained in the Bass brushing technique Use each toothbrush, twice daily, with the assigned toothbrush applied to its designated side of the mouth\n\nComplete post-trial questionnaires on comfort, ease of use, and brushing time",[57,58,28],"Dental Plaque Accumulation","Oral Hygiene Education Methods",[60,61,62],"Dual-headed toothbrush","Single-headed toothbrush","Toothbrushing technique","RECRUITING","2025-09-05",{"date":66,"type":34},"2025-09-11",{"date":68,"type":21},"2025-09",{"date":70,"type":21},"2025-12",{"name":72,"class":41},"Dar Al Uloom University",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":16,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":42},"100525520","effectiveness-of-dual-light-electric-toothbrush-vs-manual-toothbrush-in-orthodontic-patients-undergoing-oral-surgery-100525520","NCT06122805","Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery","Effectiveness of Dual Light Therapy Electric Toothbrush vs.Manual Toothbrush on Periodontal Health of Orthodontic Patients Undergoing Oral Surgery","Inclusion Criteria:\n\n* Patient of record of the Craniofacial and Special Care Orthodontic Clinic at Children's Hospital Los Angeles\n* Between the ages of 6 and 20 years\n* Physical status of ASA I or II\n* Diagnosis of craniofacial and\u002For isolated, complete or incomplete, bilateral or unilateral cleft lip and palate\n\nExclusion Criteria:\n\n* physical inability to brush teeth\n* cognitive inability to comprehend and follow directions.",true,"6 Years","20 Years",{"count":84,"type":21},198,[24],"The study is a randomized clinical trial to compare the effectiveness of a dual light ultrasonic toothbrush on periodontal health in orthodontic patients undergoing surgery.\n\nPatients with cleft lip and palate undergo bone graft and orthognathic surgery. The study will compare the periodontal outcomes in patients who use these toothbrushes during the post-surgical period.",[28,88,89],"Gingivitis","Cleft Lip and Palate","2024-05-09",{"date":92,"type":34},"2024-05-13",{"date":94,"type":34},"2024-03-11",{"date":96,"type":21},"2027-11-30",{"name":98,"class":41},"Children's Hospital Los Angeles"]