[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"total-thyroidectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:total-thyroidectomy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100545529","impact-of-manual-therapy-on-laryngeal-function-following-total-thyroidectomy-100545529",false,"NCT06383091","Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy","Man Total Thy","Inclusion Criteria:\n\n* The study population consists of individuals with malignant or benign thyroid disease scheduled to undergo total thyroidectomy\n* native speakers of English\n* All patients will be greater than or equal to 18 years of age\n\nExclusion Criteria:\n\n* Participants will be excluded if they have completed voice therapy prior\n* are current smokers\n* have organic vocal fold pathology or clear mucosal changes to the vocal folds that can affect vibration (e.g., vocal fold scar, polyp, or nodules),\n* pre-existing unilateral or bilateral vocal fold paralysis\n* have had prior surgical neck or chest history including central or lateral neck dissection\n* pre- or post-operative abscess or inflammation\n* have a history of head, neck, or chest radiation, diagnosed baseline oral or pharyngeal dysphagia\n* have recently started taking in the last 3 months, plan to start taking or increase the level of testosterone during the treatment period\n* greater than 10% otherwise unexplained weight loss\n* had a recent aspiration pneumonia","ALL","18 Years",{"count":19,"type":20},20,"ESTIMATED","INTERVENTIONAL",[23],"NA","In this clinical trial, the investigators are seeking to learn if a course of voice therapy, including neck massage, stretches and pain science education in addition to voice exercise and scar massage will effectively treatment patient complaints of swallowing or voice changes after total thyroidectomy as compared to voice exercise and scar massage alone.\n\nThe main questions it aims to answer are:\n\nWill neck massage, stretches and pain science education reduce patient complaints of swallowing changes after total thyroidectomy?\n\nWill neck massage, stretches and pain science education reduce patient complaints of voice changes after total thyroidectomy?\n\nWill neck massage, stretches and pain science education reduce patient complaints of scar tethering and quality changes after total thyroidectomy?\n\nWill neck massage, stretches and pain science education improve quality of life after total thyroidectomy?\n\nParticipants will:\n\nParticipate in 4 visits with the participant's endocrine\u002Flaryngology surgeon. One prior and 3 after surgery for endoscopic evaluation and tests.\n\nParticipate in 5 Speech-Language Pathology Sessions for intervention exercises and tests. One prior and 4 after surgery.\n\nComplete a journal of the participant's Home Exercise Practice",[26],"Total Thyroidectomy",[28,29,30,31],"manual","pain neuroscience education","total thyroidectomy","Speech Pathology","RECRUITING","2026-06-17",{"date":35,"type":36},"2026-06-22","ACTUAL",{"date":38,"type":36},"2024-06-03",{"date":40,"type":20},"2027-12",{"name":42,"class":43},"Johns Hopkins University","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":21,"phases":53,"briefSummary":54,"conditions":55,"keywords":59,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100624939","comparing-pteye-assisted-versus-conventional-total-thyroidectomy-100624939","NCT07416149","Comparing PTeye-assisted Versus Conventional Total Thyroidectomy","Reducing Post-operative Hypoparathyroidism With Probe-based Near Infrared Autofluorescence (NIRAF)- Assisted Total Thyroidectomy Versus Conventional Total Thyroidectomy, a Randomized-controlled Trial","Inclusion Criteria:\n\n* Adult patients ≥18 years of age\n* Undergoing total thyroidectomy, or completion total thyroidectomy\n* Pre-operative serum adjusted calcium levels within normal ranges\n\nExclusion Criteria:\n\n* Patients on pre-operative calcium or vitamin D supplements\n* Patients with pre-operative vitamin D deficiency, defined as serum vitamin D\\\u003C30nmol\u002FL\n* Patients with untreated primary or secondary hyperparathyroidism\n* Patient with known non-surgical hypoparathyroidism diseases\n* Patients with estimated glomerular filtration rate \\\u003C30ml\u002F1.73m2\u002Fmin, on dialysis, or having a history of kidney transplant",{"count":52,"type":20},210,[23],"This is a prospective, single-blinded, randomized controlled trial to evaluate whether PTeye™ can reduce post-operative hypoparathyroidism (PH). The study will enroll consecutive patients undergoing total thyroidectomy in a teritary endocrine surgery unit in Hong Kong, randomizing them into receiving conventional surgery versus PTeye™-assisted surgery. Subjects will be assigned to the two groups before surgery. Subjects will be under medical care as in usual practice.",[56,57,58,26],"Hypocalcemia","Parathyroid","Hypoparathyroidism Post-surgical",[60,61,62,63,64,65],"Thyroidectomy","calcium","hypocalcemia","post operation","hypoparathyroidism","PTeye™ parathyroid detection system","2026-02-12",{"date":68,"type":36},"2026-02-17",{"date":70,"type":36},"2025-09-16",{"date":72,"type":20},"2028-12-31",{"name":74,"class":43},"The University of Hong Kong",1]