[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"transcranial-doppler-ultrasound\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:transcranial-doppler-ultrasound":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,39],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":16,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100617722","diagnostic-value-of-transcranial-doppler-ultrasound-for-evaluating-neonatal-craniocerebral-injuries-100617722",false,"NCT07322315","Diagnostic Value of Transcranial Doppler Ultrasound for Evaluating Neonatal Craniocerebral Injuries","Inclusion Criteria:\n\n* Both sexes.\n* High-risk neonates with any of the following:\n\n  * Critically ill neonates.\n  * Neonatal sepsis.\n  * Neonatal encephalopathy includes hypoxic-ischemic encephalopathy.\n  * Respiratory distress.\n  * Neonatal seizures.\n  * Birth asphyxia.\n  * Signs and or symptoms of central nervous system disorders like microcephaly, macrocephaly, hypotonia, unexplained poor feeding,\n  * Neonates born out of traumatic\u002Finstrumental labor.\n  * Suspected metabolic disturbances.\n  * Neonates with low APGAR score (\\\u003C7).\n  * Neonates with low birth weight (\\\u003C2.5 kg).\n\nExclusion Criteria:\n\n* Congenital malformations.\n* Genetic metabolic diseases or other severe complications.\n* Severe intrauterine infection.","ALL","37 Weeks",{"count":18,"type":19},60,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate the diagnostic value of transcranial Doppler ultrasonography (TCD) for evaluating neonatal craniocerebral injuries.",[23,24,25],"Diagnostic Value","Transcranial Doppler Ultrasound","Neonatal Craniocerebral Injuries","RECRUITING","2026-01-07",{"date":29,"type":30},"2026-01-08","ACTUAL",{"date":32,"type":30},"2026-01-06",{"date":34,"type":19},"2026-12-30",{"name":36,"class":37},"Kafrelsheikh University","OTHER",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":15,"minAge":47,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":50,"conditions":51,"keywords":59,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":5},"100591382","early-wake-up-predictors-after-out-of-hospital-cardiac-arrest-100591382","NCT06979700","Early WAKE-up Predictors After Out-of-Hospital Cardiac Arrest","Early Wake-up Predictors After Out-of-hospital Cardiac Arrest - an Observational, Multicenter Substudy of the DANOHCA Trial","WAKE-OHCA","Inclusion Criteria:\n\n* Age ≥18 years\n* OHCA of presumed cardiac cause\n* Sustained ROSC, defined as persistent signs of circulation and no need for chest compressions or mechanical circulatory support for 20 minutes\n* Unconsciousness (GCS \\\u003C9) (patients not able to obey verbal commands) after sustained ROSC at the time of randomization\n\nExclusion Criteria:\n\n* Females of childbearing potential if pregnancy is suspected (unless a negative HCG test can rule out pregnancy within the inclusion window)\n* Known bleeding diathesis (medically induced coagulopathy (e.g. warfarin, NOAC, clopidogrel) does not exclude the patient)\n* Suspected or confirmed acute intracranial bleeding\n* Suspected or confirmed acute stroke\n* Unwitnessed asystole\n* Known limitations in therapy and Do Not Resuscitate-order\n* Known disease making 180 days survival unlikely\n* Known pre-arrest CPC 3 or 4 functional status\n* \\>3 hours (180 minutes) from ROSC to screening\n* Systolic blood pressure \\\u003C80 mm Hg despite fluid loading\u002Fvasopressor and\u002For inotropic medication (If the systolic blood pressure is recovering during the inclusion window of 180 minutes the patient may be included)\n* Use of intra-aortic balloon pump\u002Faxial flow device\u002FECMO (If the patient is weaned and the device is removed during the inclusion window of 180 minutes the patient may be included)\n* Temperature on admission \\\u003C30°C\n* Known allergy for dexamethasone or olanzapine\n* Ongoing (within 48 h) treatment with olanzapine or dexamethasone\n* Known back or hip condition that precluded the patients from being positioned with backrest from 0 to 45-degree angle\n* Known or suspected Long QT Syndrome (LQTS)\n* Known active fungal disease. Localized skin lesions do not exclude patients from inclusion\n* Estimated body weight \\\u003C45kg","18 Years",{"count":49,"type":19},250,"WAKE-OHCA is a prospective observational substudy of the Danish Out-of-Hospital Cardiac Arrest (DANOHCA) trial, identifier NCT05895838. The aim is to collect early neuromonitoring data to identify key predictors of successful wake-up.",[52,53,54,55,56,57,24,58],"Cardiac Arrest (CA)","Anoxic Brain Injury","Comatose Survivors of Cardiac Arrest","EEG","Pupillometry","Optic Nerve Sheath Diameter","Neurological Outcome",[60,61],"wakeup","sedation","2025-11-14",{"date":64,"type":30},"2025-11-18",{"date":66,"type":30},"2025-05-13",{"date":68,"type":19},"2027-12",{"name":70,"class":37},"University of Aarhus"]