[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"transcutaneous-electric-nerve-stimulation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:transcutaneous-electric-nerve-stimulation":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,52,86,115,138],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100465768","high-frequency-rf-current-effects-on-muscle-pain-and-function-100465768",false,"NCT05345015","High Frequency RF Current Effects on Muscle Pain and Function","Acute and Chronic Effects of High Frequency RF Electrical Current on Pain and Muscle Function in Individuals With Musculoskeletal Pain","Individuals with Muscle Injury\n\nInclusion Criteria:\n\n* Age over 18 years.\n* Athletes: amateur soccer players or sprinters with regular, systematic training.\n* Suspected Grade I or II hamstring strain.\n* Cessation of training due to injury.\n* No surgical intervention in the previous year (for initial assessment as potential participants).\n\nExclusion Criteria:\n\n* History of injury to the same muscle (ipsilateral side) within the last 6 months.\n* Other injury to the posterior aspect of the thigh.\n* Other injuries or chronic pain in the trunk or lower limbs.\n* Use of non-steroidal anti-inflammatory drugs (NSAIDs) in the 3 months prior to the injury.\n\nIndividuals with Acute Low Back Pain\n\nInclusion Criteria:\n\n* Age over 18 years.\n* Pain located between the lower ribs and the gluteal folds (top of the buttocks).\n* Pain occurred on fewer than half of the days over the preceding six months.\n* Pain intensity $\\\\ge$ 6\u002F10 on the Visual Analogue Scale (VAS).\n* Pain related to one or more of the following:\n\n  * Lumbar facet joints\n  * Sacroiliac joints\n  * Lumbar intervertebral discs\n  * Muscles, tendons, or ligaments of the lumbar and sacral region\n  * Other bony structures of the lumbar spine\n* Discontinuation of non-steroidal anti-inflammatory drugs (NSAIDs) or analgesics:\n\n  * 1 day prior to measurement\n  * 48 hours after measurement\n\nExclusion Criteria:\n\n* Radiographic evidence of inflammatory disease affecting the spine.\n* Spinal fracture.\n* Significant genetic structural abnormality of the spine.\n* Pregnancy.\n* Psychiatric disorders.\n* Receipt of systemic medication or treatment in the last 3 months.\n* Presence of neurological deficits (sensory, motor, or reflexes).\n* Receipt of TENS or TECAR therapy within the last year.\n\nIndividuals with Chronic Low Back Pain\n\nInclusion Criteria:\n\n* Episodes of low back pain (between the lower rib margin and the gluteal fold) for at least half of the days during the last 6 months.\n* Pain intensity $\\\\ge$ 20% on the Visual Analogue Scale (VAS).\n\nExclusion Criteria:\n\n* Spinal stenosis.\n* Radiographic evidence of inflammatory disease affecting the spine.\n* Vertebral fracture.\n* Presence of spondylolisthesis or spondylolytic lesion (spondylolysis).\n* Significant genetic structural abnormality of the spine.\n* Daily, severe low back pain.\n* Pregnancy.\n* Use of medications that might influence heart rate or blood pressure.\n* Psychiatric disorders.","ALL","18 Years","65 Years",{"count":20,"type":21},200,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to examine the acute and chronic effects of high frequency electrical current transfer (frequently called \"TECAR\") on pain and functional movement in individuals with a musculoskeletal injury or pain. The participants will be assigned into an experimental or a control group and outcome measures will be measured prior to, after, 24 and 48 hours following a single intervention session (Acute effects) as well as 3 and 6 months after the intervention (chronic effects).",[27,28,29,30,31,32,33],"Transcutaneous Electric Nerve Stimulation","Chronic Low-back Pain","Hamstring Injury","Muscle; Injury, Quadriceps (Thigh)","Physical Therapy","Calf Muscle Pulled","Acute Low Back Pain",[35,36,37,38],"Sport injuries","TECAR therapy","Low back pain","Muscle injury","RECRUITING","2026-06-23",{"date":42,"type":43},"2026-06-26","ACTUAL",{"date":45,"type":43},"2022-09-01",{"date":47,"type":21},"2029-12-31",{"name":49,"class":50},"Aristotle University Of Thessaloniki","OTHER",2,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":16,"minAge":60,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":22,"phases":63,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":85},"100560196","the-effect-of-intraoral-transcutaneous-electrical-nerve-stimulation-in-orthodontics-pain-100560196","NCT06573996","The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation in Orthodontics Pain","The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation (TENS) on Pain Perception During Orthodontic Alignment and Leveling: A Randomized Clinical Trial","Inclusion Criteria:\n\nGeneral Health: Patients who are generally healthy.\n\nOrthodontic Treatment: Patients undergoing orthodontic treatment that requires the use of full-fixed appliances.\n\nNo Pain Medication: Patients not currently taking any medications for pain management.\n\nExclusion Criteria:\n\nPatients with a history of seizures\n\nPatients with or with a history of cardiac arrhythmias or pacemaker treatment\n\nPatients taking any over-the-counter or prescription pain medication during the testing period.",true,"12 Years",{"count":62,"type":21},150,[24],"The goal of this clinical trial is to determine whether an intraoral Transcutaneous Electrical Nerve Stimulation (TENS) device can reduce pain during orthodontic alignment and leveling in adolescents and adults. The study aims to compare the effectiveness of the TENS device in reducing pain on one side of the mouth, where the device is used, to the other side, where a non-functioning (placebo) device is applied.\n\nThe primary questions this study aims to answer are:\n\nDoes the TENS device effectively reduce pain during orthodontic treatment compared to the placebo? How do patients pain levels differ between the treated and untreated sides of the mouth?\n\nParticipants will:\n\nHave an orthodontic appliance placed on their teeth. Experience the TENS device being applied to one side of their mouth for 2.5 minutes immediately after the appliance placement (brackets and wires).\n\nReport their pain levels at various intervals after the procedure (immediately, 2 hours, 6 hours, 12 hours, 24 hours, 48 hours, and 72 hours).\n\nThis study includes up to 150 participants who are undergoing routine orthodontic treatment. The findings will help researchers understand whether the TENS device can effectively reduce discomfort during orthodontic procedures, potentially leading to better patient care and comfort.",[66,67,27,68],"Orthodontic Appliance","Pain","Orthodontic Appliance Complication",[70,71,72,73,74,75],"Orthodontic Pain","TENS Therapy","Orthodontic Alignment","Randomized Clinical Trial","Transcutaneous Electrical Nerve Stimulation (TENS)","Dental Pain Eraser","2026-02-11",{"date":78,"type":43},"2026-02-17",{"date":80,"type":43},"2024-09-16",{"date":82,"type":21},"2029-09-01",{"name":84,"class":50},"University of the Pacific",1,{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":4,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":22,"phases":96,"briefSummary":97,"conditions":98,"keywords":102,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":85},"100589707","transcutaneous-auricular-vagus-nerve-stimulation-and-quality-of-recovery-after-major-noncardiac-surgery-100589707","NCT06957912","Transcutaneous Auricular Vagus Nerve Stimulation and Quality of Recovery After Major Noncardiac Surgery","Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Quality of Recovery After Major Noncardiac Surgery: A Randomized Trial.","Inclusion Criteria:\n\n1. Aged ≥18 years but \\\u003C85 years.\n2. Scheduled for elective or limited-time noncardiac surgery with expected duration ≥2 hours.\n\nExclusion Criteria:\n\n1. Lesions or infections of the auricle skin.\n2. Recent or long-term use of cholinergic or anticholinergic medications.\n3. Neurosurgery.\n4. Expected mechanical ventilation with intubation for ≥1 day after surgery.\n5. Diagnosed schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis before surgery.\n6. Preoperative left ventricular ejection fraction (LVEF) \\\u003C30%, or those with sick sinus syndrome, sinus bradycardia (heart rate \\\u003C50 beats per minute), atrioventricular block of grade II or above, or implanted pacemaker.\n7. Inability to communicate due to coma, severe dementia, or language barrier before surgery, or unable to cooperate with intervention.\n8. American Society of Anesthesiologists physical status grade \\>IV, or estimated survival \\\u003C24 hours.","85 Years",{"count":95,"type":21},320,[24],"Transcutaneous auricular vagus nerve stimulation (taVNS) is a novel non-invasive neuromodulation technique. Existing evidence suggested that taVNS improves pain management, sleep quality, inflammatory responses, and gastrointestinal recovery after surgery. This study is designed to test the hypothesis that perioperative use of taVNS may improve quality of recovery in patients after major noncardiac surgery.",[99,27,100,101],"Vagus Nerve Stimulation","Noncardiac Surgery","Quality of Recovery",[103,104,105],"Transcutaneous auricular vagus nerve stimulation","Noncardiac surgery","Quality of recovery","2025-06-02",{"date":108,"type":43},"2025-06-03",{"date":110,"type":43},"2025-05-13",{"date":112,"type":21},"2026-09",{"name":114,"class":50},"Peking University First Hospital",{"id":116,"slug":117,"hasResults":11,"nctId":118,"briefTitle":119,"officialTitle":119,"acronym":4,"eligibilityCriteria":120,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":121,"enrollmentInfo":122,"targetDuration":4,"studyType":22,"phases":124,"briefSummary":125,"conditions":126,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":85},"100556626","effect-of-transcutaneous-auricular-electroacupuncture-on-sleep-disturbances-in-patients-with-rheumatoid-arthritis-a-randomized-double-blind-clinical-trial-100556626","NCT06527547","Effect of Transcutaneous Auricular Electroacupuncture on Sleep Disturbances in Patients With Rheumatoid Arthritis: A Randomized Double-Blind Clinical Trial","Inclusion Criteria:\n\n1. Meets the 2010 ACR\u002FEULAR criteria for rheumatoid arthritis.\n2. Poor sleep quality (PSQI score \\> 7).\n3. Disease activity is moderate to low or in remission (DAS28 score ≤ 5.1).\n4. No risk of sleep apnea (STOP-Bang questionnaire \\\u003C 3).\n5. Aged between 18 and 70.\n6. The type and dosage of rheumatoid arthritis medication must be stable for at least 4 weeks.\n7. Signed informed consent.\n\nExclusion Criteria:\n\n1. People with acute infectious diseases, whether generalized or localized;\n2. Those with severe internal organ diseases (such as coronary heart disease, arrhythmia, malignant tumors, renal failure, etc.);\n3. Those working night shifts during the intervention period;\n4. Those with other rheumatic diseases such as systemic lupus erythematosus, fibromyalgia, and Sjogren's syndrome;\n5. Those undergoing treatment with steroids, sleeping pills, antidepressants, or antipsychotics;\n6. Pregnant and breastfeeding women;\n7. Those who cannot tolerate transcutaneous auricular electrostimulation.","72 Years",{"count":123,"type":21},52,[24],"The purpose of this clinical trial is to determine whether transcutaneous auricular vagus nerve stimulation (taVNS) is suitable for improving sleep disorders in patients with rheumatoid arthritis (RA). It will also evaluate the safety of taVNS. The main questions it aims to answer are:\n\nCan taVNS improve the sleep quality of RA patients? What medical issues might RA patients experience while receiving taVNS treatment? Researchers will compare taVNS with a placebo (a similar substance that does not contain the actual treatment) to see if taVNS is effective in improving sleep disorders in RA patients.\n\nParticipants will:\n\nReceive taVNS or sham stimulation daily for 4 weeks Keep a daily sleep diary and visit the hospital once a week for check-ups and tests Record their sleep quality and related symptoms This study aims to provide a new, safe, and effective non-drug therapy for sleep disorders related to RA.",[27,127,128],"Rheumatoid Arthritis","Sleep Quality","2025-04-10",{"date":131,"type":43},"2025-04-13",{"date":133,"type":43},"2024-06-06",{"date":135,"type":21},"2025-12-31",{"name":137,"class":50},"Juan Jiao",{"id":139,"slug":140,"hasResults":11,"nctId":141,"briefTitle":142,"officialTitle":142,"acronym":4,"eligibilityCriteria":143,"healthyVolunteers":59,"sex":144,"minAge":17,"maxAge":4,"enrollmentInfo":145,"targetDuration":4,"studyType":22,"phases":147,"briefSummary":148,"conditions":149,"keywords":152,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":85},"100393183","transcutaneous-electrical-nerve-stimulation-for-post-cesarean-pain-control-100393183","NCT04399707","Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Control","Inclusion Criteria:\n\n\\- Women undergoing scheduled or non-urgent cesarean section\n\nExclusion Criteria:\n\n* Non-English speaking\n* Subjects with a history of chronic pain or chronic opioid use\n* Pre-operative use of opioids for more than 1 week in the preceding 6 months\n* Previous exposure to the TENS unit\n* Women with an allergy or contraindication to narcotics\u002FNSAIDs\u002Facetaminophen\n* Subjects who had a midline vertical skin incision during this operation\n* Subjects who did not receive intrathecal opioids at the time of their cesarean delivery\n* Adhesive allergies\n* Subjects with a pacemaker (due to the unknown effects of the TENS on the electrical activity of the heart)\n* Intraoperative general anesthesia\n* Inability to consent to the study\n* Postpartum tubal ligation","FEMALE",{"count":146,"type":21},180,[24],"Purpose of study is to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for post-operative pain control after a cesarean delivery compared to placebo and no TENS.",[27,150,151],"Analgesia","Cesarean Section",[153,154,155],"TENS","Transcutaneous electric nerve stimulation","Cesarean analgesia","2020-05-21",{"date":158,"type":43},"2020-05-26",{"date":160,"type":43},"2020-01-29",{"date":162,"type":21},"2021-05",{"name":164,"class":50},"Hawaii Pacific Health"]