[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"transudative-pleural-effusion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:transudative-pleural-effusion":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100632455","evaluation-of-transthoracic-ultrasonography-in-differentiating-pleural-effusions-100632455",false,"NCT07513909","Evaluation of Transthoracic Ultrasonography in Differentiating Pleural Effusions","Evaluation of Transthoracic Ultrasonography in Differentiating Exudative From Transudative Pleural Effusions","Inclusion Criteria:\n\n* Adult patients aged ≥18 years of either sex\n* Clinically and radiologically documented pleural effusion (confirmed by chest X-ray and\u002For thoracic ultrasound)\n* Patients scheduled for diagnostic or therapeutic thoracentesis as part of their standard clinical care\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Patients with a history of prior pleural interventions, including chemical or surgical pleurodesis or previous chest tube insertion on the affected side\n* Patients with absolute contraindications to thoracentesis (e.g., uncorrectable coagulopathy, uncooperative patients, or hemodynamic instability)\n* Poor transthoracic ultrasound window preventing adequate evaluation of the pleural space (e.g., due to severe obesity, extensive subcutaneous emphysema, or chest wall deformities)\n* Patients with traumatic hemothorax.","ALL","18 Years",{"count":19,"type":20},90,"ESTIMATED","OBSERVATIONAL","Pleural effusion is a condition where excess fluid builds up in the space between the lungs and the chest wall. To properly treat this condition, doctors must determine if the fluid is a \"transudate\" (usually resulting from systemic conditions like heart failure or liver disease) or an \"exudate\" (often resulting from local issues like infections, inflammation, or cancer). The standard method to classify this fluid involves inserting a needle into the chest to draw out a sample for laboratory testing, a procedure known as thoracentesis.\n\nWhile laboratory fluid analysis is highly accurate, the needle procedure carries some inherent procedural risks. This observational study aims to evaluate whether non-invasive imaging tests, specifically chest ultrasound, can accurately determine if the fluid is a transudate or an exudate.\n\nResearchers will enroll adult patients presenting with pleural effusion at Assiut University Hospital. As part of their diagnostic workup, participants will undergo a chest ultrasound and a standard diagnostic thoracentesis (fluid draw) within 24 to 48 hours of each other. The study will then evaluate the features seen on the ultrasound against the laboratory fluid analysis (the current gold standard) to see how well the non-invasive imaging performs in identifying the specific type of pleural effusion.",[24,25,26],"Pleural Effusion","Transudative Pleural Effusion","Exudative Pleural Effusion",[28,29,30,31,32,33],"Chest Ultrasound","Computed Tomography","Transudate","Exudate","Light's Criteria","Thoracentesis","NOT_YET_RECRUITING","2026-04-08",{"date":37,"type":38},"2026-04-13","ACTUAL",{"date":40,"type":20},"2026-05",{"date":42,"type":20},"2027-06",{"name":44,"class":45},"Assiut University","OTHER"]