[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"transverse-maxillary-deficiency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:transverse-maxillary-deficiency":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,42,74,103,128],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100599601","obstructive-sleep-apnea-hypopnea-syndrome-osahs-and-transverse-orthodontic-deficiency-in-children-100599601",false,"NCT07086612","Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Transverse Orthodontic Deficiency in Children","ASCOT","Inclusion Criteria:\n\n* Patient aged between 6 and 16 years\n* Patients with a transverse orthodontic deficiency (group \"CAS\")\n* Patients with another type of orthodontic deficiency (group \"CONTROL\") such as tooth rotation, crowding, mild Angle Class II or Class III dental occlusion\n* Patient who has given free, informed oral consent\n* Patient whose legal representatives have given their free written consent\n* Patient affiliated with a health insurance scheme\n\nExclusion Criteria:\n\n* Patients refusing to participate in the study\n* Patients whose legal representatives refuse to participate in the study","ALL","6 Years","16 Years",{"count":20,"type":21},102,"ESTIMATED","INTERVENTIONAL",[24],"NA","OSAHS (Obstructive Sleep Apnea Hypopnea Syndrome) in children is a frequent respiratory disorder, whose prevalence is estimated at between 1.2 and 5.7%, and which, if left untreated, can cause severe medical complications. This prevalence tends to be underestimated. Diagnosis is made following a clinical examination noting the presence of characteristic clinical and polysomnographic criteria. Multidisciplinary management has been widely described in the literature, and various therapeutic options have been indicated. Rapid maxillary expansion has proved highly effective in the treatment of this condition. This syndrome is a real public health problem and must be diagnosed as early as possible. Through our research, we would like to study whether there is a causal link between an orthodontic problem of the transverse direction and the presence of SAHOS in children. In other words, we would like to assess whether children who clinically present an orthodontic deficiency of their transverse dimension are more likely to develop SAHOS than children without this deficit. If this proves to be true, then a new clinical sign could enable certain healthcare professionals to detect this syndrome early, and be able to refer patients to physicians as soon as possible.",[27,28],"Obstructive Sleep Apnea","Transverse Maxillary Deficiency","RECRUITING","2026-03-27",{"date":32,"type":33},"2026-03-30","ACTUAL",{"date":35,"type":33},"2025-11-06",{"date":37,"type":21},"2026-09-30",{"name":39,"class":40},"Fondation Hôpital Saint-Joseph","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":69,"completionDateStruct":70,"leadSponsor":72,"locationsCount":41},"100631401","quad-helix-vs-rme-for-posterior-cross-bite-in-egyptian-children-100631401","NCT07500194","Quad Helix vs RME for Posterior Cross-bite in Egyptian Children","Quad Helix Versus Rapid Maxillary Expanders in the Treatment of Posterior Cross-bite During Mixed Dentition in a Sample of Egyptian Children: A Randomized Clinical Study.","Expansion","Inclusion Criteria:\n\n1. Children aged 9-12 years in the mixed dentition stage\n2. Presence of posterior cross-bite due to transverse maxillary deficiency\n3. No previous history of orthodontic treatment\n4. Good oral hygiene and cooperative behavior\n5. No significant antero-posterior or vertical skeletal discrepancies\n\nExclusion Criteria:\n\n1. Patient with craniofacial anomalies\n2. Presence of systemic diseases or syndromes affecting bone metabolism\n3. Extensive dental caries or untreated periodontal disease\n4. History of trauma or surgery affecting the maxilla or mandible","9 Years","12 Years",{"count":53,"type":21},20,[24],"This randomized clinical trial aims to evaluate and compare the effectiveness of the Quad Helix (QH) appliance versus Rapid Maxillary Expanders (RME) in treating posterior cross-bite in Egyptian children during the mixed dentition stage. The study will also assess patient comfort and pain levels associated with each appliance.",[57,58,28],"Posterior Crossbite","Maxillary Expansion",[60,61,62,63,64,65],"Quad Helix","Rapid Maxillary Expansion","Posterior cross-bite","Mixed Dentition","Egyptian children","Randomized clinical trials","NOT_YET_RECRUITING","2026-03-24",{"date":32,"type":33},{"date":32,"type":21},{"date":71,"type":21},"2028-03-31",{"name":73,"class":40},"Al-Azhar University",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":81,"maxAge":51,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":41},"100630269","effects-of-invisalign-palatal-expander-vs-rapid-palatal-expander-with-facemask-in-growing-class-iii-patients-100630269","NCT07485478","Effects of Invisalign Palatal Expander vs Rapid Palatal Expander With Facemask in Growing Class III Patients","Effects of the Invisalign® Palatal Expander (IPE) vs. Rapid Palatal Expander With Facemask in Growing Skeletal Class III Patients: A CBCT Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients aged between 8 and 12 years\n* Patients in the mixed dentition or early permanent stage have at least three stable teeth per quadrant, good oral hygiene, and healthy periodontal tissues\n* Patients with maxilla-mandibular discrepancies; skeletal class III is indicated by an ANB angle \\\u003C 0 degrees or a Wits appraisal value that is negative, and Maxillary constriction is characterized by posterior crossbite teeth or having a maxillary width below the norm value.\n\nExclusion Criteria:\n\n* Patients with craniofacial anomalies such as cleft lip and palate\n* Patient with a prior history of maxillary expansion.\n* Patients who have systemic conditions that contraindicate orthodontic treatment.","8 Years",{"count":83,"type":21},24,[24],"The goal of this clinical trial is to compare two types of palatal expanders used with a facemask in children who have skeletal Class III and a narrow upper jaw. The study will compare the Invisalign Palatal Expander (IPE) and the Rapid Palatal Expander (RPE). Researchers want to learn how these devices affect jaw bones and tooth position. They also want to learn about children's and parents' experiences during treatment.\n\nThe main questions this study aims to answer are:\n\nDo IPE and RPE widen the upper jaw differently?\n\nDo they cause different changes in tooth position?\n\nHow do children and parents describe their treatment experience?\n\nParticipants will be children aged 8 to 12 years who have skeletal Class III and a narrow upper jaw. Children with craniofacial conditions, previous upper jaw expansion, or medical conditions that prevent orthodontic treatment will not take part. Parents and children must give consent before joining the study.\n\nParticipants will:\n\nBe assigned to receive either IPE or RPE\n\nExpand the upper jaw to 7 mm (0.25 mm per day)\n\nAfter expansion, wear a facemask for at least 12 hours per day for 6 to 8 months\n\nHave cone-beam computed tomography (CBCT) scans taken before expansion, after expansion, and after facemask treatment\n\nTake part in an interview with a parent after expansion\n\nResearchers will use CBCT images to measure changes in jaw bones and tooth position. The main outcomes are changes in jaw bones and tooth position. Secondary outcomes include children's and parents' experiences during treatment.",[87,28],"Skeletal Class III Malocclusion",[89,90,91,92,93],"Invisalign Palatal Expander","Rapid Palatal Expansion","Facemask","CBCT","Retrognathic maxilla","2026-03-16",{"date":96,"type":33},"2026-03-20",{"date":98,"type":21},"2026-03",{"date":100,"type":21},"2027-10",{"name":102,"class":40},"Mahidol University",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":110,"sex":16,"minAge":51,"maxAge":111,"enrollmentInfo":112,"targetDuration":4,"studyType":22,"phases":114,"briefSummary":115,"conditions":116,"keywords":117,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":41},"100624550","three-dimensionally-printed-hyrax-versus-conventional-hyrax-for-maxillary-arch-expansion-in-adolescents-100624550","NCT07411092","Three-dimensionally Printed Hyrax Versus Conventional Hyrax for Maxillary Arch Expansion in Adolescents","Three-dimensionally Printed Hyrax Versus Conventional Hyrax for Maxillary Arch Expansion in Adolescents: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Patients aged between 12 to 17 years.\n2. Skeletal age ranges from CVMS 3 to CVMS 5.\n3. Skeletal maxillary transverse deficiency with\u002Fwithout crossbite.\n4. Cooperative and able to attend follow-up visits.\n\nExclusion Criteria:\n\n1. Previous orthodontic treatment.\n2. Craniofacial syndromes, or cleft lip and\u002For palate.\n3. Patients with vertical growth pattern.\n4. Very bad oral hygiene and active periodontal disease.\n5. Vulnerable groups such as individuals with cognitive impairments or intellectual disabilities and individuals with severe mental health disorders.",true,"17 Years",{"count":113,"type":21},22,[24],"This clinical trial aims to compare the skeletal and dental effects of conventional Hyrax expanders and 3D-printed Hyrax expanders in adolescent patients with maxillary transverse deficiency. Using cone-beam computed tomography (CBCT) and digital models, the study evaluates the precision, customization, and treatment outcomes of both appliance types to inform evidence-based orthodontic treatment planning.",[28,58],[58,118],"Hyrax expander","2026-02-08",{"date":121,"type":33},"2026-02-13",{"date":123,"type":33},"2025-08-01",{"date":125,"type":21},"2027-01-01",{"name":127,"class":40},"Ain Shams University",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":132,"acronym":4,"eligibilityCriteria":133,"healthyVolunteers":11,"sex":16,"minAge":134,"maxAge":135,"enrollmentInfo":136,"targetDuration":4,"studyType":138,"phases":4,"briefSummary":139,"conditions":140,"keywords":141,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":156},"100618974","digital-vs-analog-inputs-in-cadcam-orthodontics-a-comparative-clinical-evaluation-of-palatal-expander-fabrication-workflow-100618974","NCT07338591","Digital vs. Analog Inputs in CAD\u002FCAM Orthodontics: A Comparative Clinical Evaluation of Palatal Expander Fabrication Workflow","Inclusion Criteria:\n\n* • Aged between 8 and 13 years with transverse maxillary deficiency ( with unilateral or bilateral crossbite ,with or without anterior cross bite)\n\n  * Indicated for tooth-borne maxillary expansion\n  * Good oral hygiene and cooperative behavior\n  * No prior orthodontic treatment\n\nExclusion Criteria:\n\n* • Craniofacial anomalies or syndromes\n\n  * Requirement for surgically assisted expansion\n  * Poor oral hygiene or high caries index","8 Months","13 Months",{"count":137,"type":21},36,"OBSERVATIONAL","36 patients with unilateral or bilateral cross bite treated with hyrax expanders fabricated through three distinct workflows: fully conventional (physical impression + manual fabrication), hybrid (physical impression + CAD\u002FCAM fabrication), and fully digital (intraoral scanning + CAD\u002FCAM fabrication). To evaluate and compare the clinical fit, workflow efficiency, and patient\u002Fclinician satisfaction of palatal expanders fabricated using traditional, hybrid digital, and fully digital workflows.",[28],[142,143,144,145,146],"Palatal Expander","Hyrax Expander","CAD\u002FCAM Orthodontics","Digital Workflow","Intraoral Scanning","2026-01-03",{"date":149,"type":33},"2026-01-14",{"date":151,"type":21},"2025-12-25",{"date":153,"type":21},"2027-07-25",{"name":155,"class":40},"Mansoura University",2]