[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"transversus-abdominis-plane-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:transversus-abdominis-plane-block":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,51,77,102,118,143],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100637651","phase-4-transversus-abdominis-plane-and-rectus-sheath-block-for-robotic-colectomy-100637651",false,"NCT07624916","Transversus Abdominis Plane and Rectus Sheath Block for Robotic Colectomy","Impact of Transversus Abdominis Plane Block Combined With Rectus Sheath Block on Postoperative Pain Management in Patients Undergoing Elective Robotic Colectomy","Inclusion Criteria:\n\n* Patients scheduled for elective robotic colorectal cancer surgery for the first time\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years or age \\> 80 years\n* Allergic to any medication in the protocol\n* Infection over the injection site\n* Chronic pain history\n* Severe hepatic or renal insufficiency\n* Pregnancy\n* Emergency surgery\n* Refusal to join the study","ALL","20 Years","80 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","This study aimed to evaluate the impact of ultrasound-guided bilateral transversus abdominis plane block combined with rectus sheath block on postoperative pain and recovery after robotic colectomy under an enhanced recovery after surgery (ERAS) protocol.",[27,28,29,30,31],"Rectus Sheath Block","Transversus Abdominis Plane Block","Enhanced Recovery After Surgery","Robotic Surgery","Colorectal Cancer",[33,34,35,36,37],"colorectal cancer","robotic colectomy","enhanced recovery after surgery","transversus abdominis plane block","rectus sheath block","NOT_YET_RECRUITING","2026-05-30",{"date":41,"type":42},"2026-06-03","ACTUAL",{"date":44,"type":21},"2026-06-01",{"date":46,"type":21},"2028-03-31",{"name":48,"class":49},"Tri-Service General Hospital","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":58,"minAge":59,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":64,"conditions":65,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":73,"leadSponsor":75,"locationsCount":50},"100640200","combination-of-superior-hypogastric-plexus-block-and-transversus-abdominis-plane-block-in-abdominal-hysterectomies-100640200","NCT07606781","Combination of Superior Hypogastric Plexus Block and Transversus Abdominis Plane Block in Abdominal Hysterectomies","Analgesic Effect of Combination of Superior Hypogastric Plexus Block and Transversus Abdominis Plane Block in Abdominal Hysterectomies: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* American Society of Anesthesiology (ASA) physical status I-II.\n* Undergoing abdominal hysterectomies under general anesthesia (GA).\n\nExclusion Criteria:\n\n* History of allergies to local anesthetics.\n* Body mass index (BMI) \\>35 kg\u002Fm2.\n* Opioid dependency.\n* Cognitive impairment.\n* Bleeding or coagulation disorders.\n* Psychiatric and neurological disorder.\n* Local infection at the site of injection.\n* Severe heart, lung, liver, and renal dysfunction.","FEMALE","18 Years",{"count":61,"type":21},44,[63],"NA","This study aims to evaluate the analgesic effect of superior hypogastric plexus block combined with transversus abdominis plane block in abdominal hysterectomies.",[66,28,67],"Superior Hypogastric Plexus Block","Abdominal Hysterectomies","RECRUITING","2026-05-23",{"date":71,"type":42},"2026-05-27",{"date":69,"type":42},{"date":74,"type":21},"2026-10-01",{"name":76,"class":49},"Tanta University",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":16,"minAge":59,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":22,"phases":87,"briefSummary":88,"conditions":89,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":50},"100628181","the-efficacy-and-safety-of-liposomal-bupivacaine-for-transversus-abdominis-plane-block-in-relieving-postoperative-pain-after-laparoscopic-surgery-in-gynecologic-oncology-100628181","NCT07458295","The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery in Gynecologic Oncology","The Efficacy and Safety of Liposomal Bupivacaine Plus Bupivacaine Transversus Abdominis Plane Block for Postoperative Pain in Patients Undergoing Laparoscopic Surgery in Gynecologic Oncology:A Multi-Center Randomized Controlled Trial","Inclusion Criteria:\n\n1. Patients scheduled for elective Laparoscopic Surgery in Gynecologic Oncology under general anesthesia;\n2. Ages 18 to 64 years old；\n3. American Society of Anesthesiologists (ASA) physical status of I-III；\n4. Glasgow Coma Scale (GCS) score of 15；\n5. Patients must be able to understand the nature and potential personal consequences of the clinical trial, signing of the informed consent form.\n\nExclusion Criteria:\n\n1. History of chronic pain syndrome of any cause.\n2. Patients with heart conduction block (sinus block or atrioventricular block).\n3. Patients with unstable coronary artery disease.\n4. Patients with gastric ulcer or gastric bleeding.\n5. Patients with diabetes and are being treated with insulin.\n6. Subjects with coagulation dysfunction (prothrombin time or activated partial thromboplastin time is higher than the normal threshold) or patients who are taking oral anticoagulants for other medical reasons and have not stopped it before surgery, such as warfarin or new anticoagulants rivaroxaban or dabigatran.\n7. Patients with abnormal liver function: alanine aminotransferase (ALT) and\u002For aspartate aminotransferase (AST) \\> 2× the upper limit of normal (ULN) or total bilirubin (TBIL) ≥ 1.5×ULN.\n8. Patients with renal impairment (serum creatinine \\> 176 µmol\u002FL) or receiving dialysis treatment within 28 days before surgery.\n9. Patients with a history of diagnosed mental illness or currently taking psychotropic medication.\n10. Excessive alcohol or drug abuse, chronic opioid use (more than 2 weeks or 3 days per week for more than 1 month), use of drugs with confirmed or suspected sedative or analgesic effects, or use of any painkiller within 24 h before surgery.\n11. Pregnancy or breastfeeding.\n12. Extreme body mass index (BMI) (\\\u003C 15 or \\> 35).\n13. Participation in another interventional trial that interferes with the intervention or outcome of this trial.\n14. Patients with a history of allergy to local anaesthetics or one of the study drugs.","64 Years",{"count":86,"type":21},110,[63],"Laparoscopic surgery, characterized by minimal invasiveness, rapid recovery, and shorter hospital stays, has been widely adopted in Gynecologic Oncology. However, the elevation and stretching of the diaphragm following pneumoperitoneum, combined with increased intra-abdominal pressure compressing visceral organs and causing ischemia-hypoxia, can trigger systemic inflammatory responses and lead to postoperLaparoscopic surgery, characterized by minimal invasiveness, rapid recovery, and shorter hospital stays, has been widely adopted in gynecological procedures. However, the elevation and stretching of the diaphragm following pneumoperitoneum, combined with increased intra-abdominal pressure compressing visceral organs and causing ischemia-hypoxia, can trigger systemic inflammatory responses and lead to postoperative pain. Inadequate or delayed pain management may prolong hospitalization, and some patients may develop chronic pain, resulting in altered behavioral patterns. As one of the analgesic strategies after abdominal surgery, transversus abdominis plane block (TAPB) not only reduces opioid consumption and the incidence of complications but also avoids adverse effects associated with epidural analgesia. Nevertheless, the analgesic duration provided by a single-injection TAPB is limited, while continuous TAPB faces constraints in clinical application due to challenges such as catheter fixation.Inadequate or delayed pain management may prolong hospitalization, and some patients may develop chronic pain, resulting in altered behavioral patterns. As one of the analgesic strategies after abdominal surgery, TAPB not only reduces opioid consumption and the incidence of complications but also avoids adverse effects associated with epidural analgesia. Nevertheless, the analgesic duration provided by a single-injection TAPB is limited, while continuous TAPB faces constraints in clinical application due to challenges such as catheter fixation. Liposomal bupivacaine(LB) is a novel, long-acting, sustained-release amide-type local anesthetic, providing localized analgesic effects for up to 72 hours.However, its efficacy and safety in laparoscopic surgery not yet been fully validated. Based on this premise, the present study aims to evaluate and compare the clinical outcomes of Ultrasound-guided TAPB utilizing liposomal bupivacaine plus bupivacaine for postoperative pain management in patients undergoing Laparoscopic Surgery in Gynecologic Oncology.",[90,91,92,28],"Laparoscopic Surgery","Gynecologic Oncology Patient","Liposomal Bupivacaine","2026-03-14",{"date":95,"type":42},"2026-03-17",{"date":97,"type":42},"2026-03-10",{"date":99,"type":21},"2027-06-30",{"name":101,"class":49},"Beijing Tiantan Hospital",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":16,"minAge":59,"maxAge":84,"enrollmentInfo":109,"targetDuration":4,"studyType":22,"phases":111,"briefSummary":112,"conditions":113,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":114,"startDateStruct":115,"completionDateStruct":116,"leadSponsor":117,"locationsCount":50},"100628180","the-efficacy-and-safety-of-liposomal-bupivacaine-for-transversus-abdominis-plane-block-in-relieving-postoperative-pain-after-laparoscopic-surgery-100628180","NCT07458282","The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery","The Efficacy and Safety of Liposomal Bupivacaine Plus Bupivacaine Transversus Abdominis Plane Block for Postoperative Pain in Patients Undergoing Laparoscopic Surgery:A Multi-Center Randomized Controlled Trial","Inclusion Criteria:\n\n1. Patients scheduled for elective laparoscopic cholecystectomy, hernia repair, and appendectomy under general anesthesia;\n2. Ages 18 to 64 years old；\n3. American Society of Anesthesiologists (ASA) physical status of I-III；\n4. Glasgow Coma Scale (GCS) score of 15；\n5. Patients must be able to understand the nature and potential personal consequences of the clinical trial, signing of the informed consent form.\n\nExclusion Criteria:\n\n1. History of chronic pain syndrome of any cause.\n2. Patients with heart conduction block (sinus block or atrioventricular block).\n3. Patients with unstable coronary artery disease.\n4. Patients with gastric ulcer or gastric bleeding.\n5. Patients with diabetes and are being treated with insulin.\n6. Subjects with coagulation dysfunction (prothrombin time or activated partial thromboplastin time is higher than the normal threshold) or patients who are taking oral anticoagulants for other medical reasons and have not stopped it before surgery, such as warfarin or new anticoagulants rivaroxaban or dabigatran.\n7. Patients with abnormal liver function: alanine aminotransferase (ALT) and\u002For aspartate aminotransferase (AST) \\> 2× the upper limit of normal (ULN) or total bilirubin (TBIL) ≥ 1.5×ULN.\n8. Patients with renal impairment (serum creatinine \\> 176 µmol\u002FL) or receiving dialysis treatment within 28 days before surgery.\n9. Patients with a history of diagnosed mental illness or currently taking psychotropic medication.\n10. Excessive alcohol or drug abuse, chronic opioid use (more than 2 weeks or 3 days per week for more than 1 month), use of drugs with confirmed or suspected sedative or analgesic effects, or use of any painkiller within 24 h before surgery.\n11. Pregnancy or breastfeeding.\n12. Extreme body mass index (BMI) (\\\u003C 15 or \\> 35).\n13. Participation in another interventional trial that interferes with the intervention or outcome of this trial.\n14. Patients with a history of allergy to local anaesthetics or one of the study drugs.",{"count":110,"type":21},318,[63],"Laparoscopic surgery has become the preferred approach for abdominal surgical interventions due to its advantages of minimal invasiveness, rapid recovery, and reduced complication rates. Despite its minimally invasive nature, postoperative pain persists and adversely affects patient recovery. In the absence of effective pain management, acute pain may progress to chronic pain. Although opioids provide reliable analgesic effects, their associated adverse reactions limit their application following minimally invasive procedures. Regional analgesia serves as the cornerstone of multimodal analgesia, and ultrasound-guided nerve block techniques have become increasingly refined. Ultrasound-guided transversus abdominis plane block(TAPB) generally fulfills intraoperative and postoperative analgesic requirements for laparoscopic surgeries by inhibiting the transmission of nociceptive stimuli in the targeted region, thereby aiding in the prevention of central sensitization. Conventional TAPB utilize local anesthetics, which demonstrate excellent efficacy in alleviating incisional pain. However, the short duration of analgesia provided by conventional local anesthetics significantly compromises their clinical utility.Liposomal bupivacaine(LB) is a novel, long-acting, sustained-release amide-type local anesthetic, providing localized analgesic effects for up to 72 hours.However, its efficacy and safety in laparoscopic surgery not yet been fully validated. Based on this premise, the present study aims to evaluate and compare the clinical outcomes of Ultrasound-guided TAPB utilizing liposomal bupivacaine plus bupivacaine for postoperative pain management in patients undergoing laparoscopic surgery.",[90,92,28],{"date":95,"type":42},{"date":97,"type":42},{"date":99,"type":21},{"name":101,"class":49},{"id":119,"slug":120,"hasResults":11,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":4,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":16,"minAge":59,"maxAge":4,"enrollmentInfo":125,"targetDuration":4,"studyType":22,"phases":127,"briefSummary":128,"conditions":129,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":139,"leadSponsor":141,"locationsCount":50},"100613941","combined-subcostal-and-lateral-transversus-abdominis-plane-block-for-postoperative-analgesia-versus-thoracic-epidural-analgesia-in-patients-undergoing-major-abdominal-cancer-surgery-100613941","NCT07273136","Combined Subcostal and Lateral Transversus Abdominis Plane Block for Postoperative Analgesia Versus Thoracic Epidural Analgesia in Patients Undergoing Major Abdominal Cancer Surgery","Safety and Efficacy of Combined Subcostal and Lateral Transversus Abdominis Plane Block for Postoperative Analgesia Versus Thoracic Epidural Analgesia in Patients Undergoing Major Abdominal Cancer Surgery","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status I-III.\n* Scheduled for major abdominal surgeries including: (e.g., gastrectomy, colectomy, hepatectomy, cystectomy, total abdominal hysterectomy, Nephrectomy, pancreatectomy).\n\nExclusion Criteria:\n\n* Intraoperative hemodynamic instability.\n* History or evidence of coagulopathy.\n* Infection or abdominal wall masses at injection site.\n* Morbid obesity.\n* Other Medical conditions including mental illness or substance abuse.\n* Known allergy to local anesthetics.\n* Chronic opioid use or chronic pain conditions.\n* Pregnancy.",{"count":126,"type":21},50,[63],"This study aims to evaluate the safety and efficacy of combined subcostal and lateral transversus abdominis plane (TAP) for postoperative analgesia versus thoracic epidural anesthesia (TEA) in patients undergoing major abdominal cancer surgery.",[130,131,28,132,133,134],"Subcostal","Lateral","Postoperative Analgesia","Thoracic Epidural Analgesia","Major Abdominal Cancer Surgery","2025-12-10",{"date":137,"type":42},"2025-12-11",{"date":135,"type":42},{"date":140,"type":21},"2026-04-01",{"name":142,"class":49},"Assiut University",{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":147,"acronym":4,"eligibilityCriteria":148,"healthyVolunteers":11,"sex":16,"minAge":59,"maxAge":149,"enrollmentInfo":150,"targetDuration":4,"studyType":22,"phases":151,"briefSummary":152,"conditions":153,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":50},"100570444","analgesic-efficacy-of-transversus-abdominis-plane-block-versus-external-oblique-block-in-patients-undergoing-elective-laparoscopic-cholecystectomy-100570444","NCT06707324","Analgesic Efficacy of Transversus Abdominis Plane Block Versus External Oblique Block in Patients Undergoing Elective Laparoscopic Cholecystectomy","Inclusion Criteria:\n\n1. Adult patients aged 18-60 years.\n2. Gender: Both males and females.\n3. BMI less than 35 kg\u002Fm2\n4. Scheduled for laparoscopic cholecystectomy surgery\n5. American Society of Anesthesiologists - ASA - I \\& II\n\nExclusion Criteria:\n\n1-ASA physical status more than II. 2-History of allergic response to local anaesthetics or any of the medications used in the study\n\n\\-","60 Years",{"count":126,"type":21},[63],"Postoperative pain management is a critical aspect of recovery following laparoscopic cholecystectomy, a commonly performed procedure for symptomatic gallbladder disease. Effective analgesia not only enhances patient comfort but also facilitates early mobilization, reduces the incidence of complications, and improves overall outcomes.\n\nOblique subcostal transversus abdominis plane block (OSTAP), one of the regional anesthesia techniques, is used in middle and upper abdominal surgeries OSTAP blocks the T6-9 intercostal nerves between the rectus abdominis and transversus abdominis muscle. Many studies have shown that OSTAP block reduces the postoperative analgesic and opioid requirement and improves the quality of postoperative pain control.",[28,154,155],"External Oblique Block","Laparoscopic Cholecystectomy","2024-11-28",{"date":158,"type":42},"2024-12-03",{"date":160,"type":21},"2024-12-01",{"date":162,"type":21},"2025-12-15",{"name":142,"class":49}]