[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"transversus-abdominis-plane-tap-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:transversus-abdominis-plane-tap-block":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,43,79,119,148,168,195],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100639984","plasma-kinetics-of-levobupivacaine-after-transversus-abdominis-plane-tap-block-in-abdominal-surgery-100639984",false,"NCT07581275","Plasma Kinetics of Levobupivacaine After Transversus Abdominis Plane (TAP) Block in Abdominal Surgery","Plasma Kinetics of Levobupivacaine After Transversus Abdominis Plane (TAP) Block in Abdominal Surgery: A Prospective Study and Definition of a Safety Window for Intravenous Lidocaine Administration","LEVO-TAP-PK","Inclusion Criteria:\n\n* Age ≥18 years\n* Scheduled elective abdominal surgery under general anesthesia\n* Planned ultrasound-guided TAP block as part of standard perioperative analgesic care\n* Able to understand and speak French sufficiently to understand the study information and consent form\n* Able and willing to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal or inability to provide informed consent\n* Known allergy or hypersensitivity to amide local anesthetics\n* Severe hepatic impairment\n* Renal impairment (estimated glomerular filtration rate \\\u003C50 mL\u002Fmin\u002F1.73 m²)\n* Contraindication to repeated blood sampling or inability to complete the sampling schedule\n* Participation in another clinical study that could affect absorption, distribution, metabolism, or elimination of local anesthetics\n* Pregnancy\n* Emergency surgery or life-threatening urgent condition\n* Immediate postoperative instability requiring intensive care transfer (e.g., hemodynamic instability)\n* Inability to understand French sufficiently for study information and consent\n* Persons requiring special legal protection for consent (e.g., minors, guardianship, incapacity to consent)","ALL","18 Years","75 Years",{"count":21,"type":22},26,"ESTIMATED","OBSERVATIONAL","This prospective single-center observational pharmacokinetic study will evaluate plasma levobupivacaine concentrations after ultrasound-guided transversus abdominis plane (TAP) block in adult patients undergoing elective abdominal surgery under general anesthesia at CHU Liège. Participants receiving TAP block as part of standard clinical care (levobupivacaine 0.375%, total volume 40 mL, maximum dose 150 mg) will undergo serial blood sampling at 3, 7, 15, 30, 60, 120, and 180 minutes after block completion. Plasma levobupivacaine concentrations will be measured using validated LC-MS\u002FMS methods. The primary objectives are to estimate maximum plasma concentration (Cmax) and time to maximum concentration (Tmax). Secondary objectives include characterization of the concentration-time profile, AUC0-180, interindividual variability, and exploratory associations with clinical factors (age, sex, BMI, type of surgery). The study also aims to inform a pragmatic safety window for subsequent intravenous lidocaine infusion used in multimodal analgesia protocols. Approximately 26 participants will be enrolled. No modification of routine anesthesia or analgesic care is required apart from study-related blood sampling.",[26,27,28,29,30],"Abdominal Surgery Patients","Transversus Abdominis Plane (TAP) Block","Pharmacokinetic Analysis","Levobupivacaine","Local Anaesthetic Systemic Toxicity","NOT_YET_RECRUITING","2026-05-06",{"date":34,"type":35},"2026-05-12","ACTUAL",{"date":37,"type":22},"2026-07-01",{"date":39,"type":22},"2026-12-15",{"name":41,"class":42},"University of Liege","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":17,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":55,"studyType":23,"phases":4,"briefSummary":56,"conditions":57,"keywords":62,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":78},"100611562","transversalis-fascia-plane-versus-transversus-abdominis-plane-block-for-postoperative-analgesia-in-children-100611562","NCT07242196","Transversalis Fascia Plane Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Children","Comparison of the Analgesic Effects of Ultrasound-Guided Transversalis Fascia Plane Block and Transversus Abdominis Plane Block in Pediatric Laparoscopic Surgery","Inclusion Criteria:\n\n* Pediatric patients aged 6 months to 16 years\n* Classified as ASA physical status I or II\n* Scheduled to undergo laparoscopic surgery under general anesthesia\n\nExclusion Criteria:\n\n* Patients classified as ASA physical status III or IV\n* Known allergy or hypersensitivity to local anesthetic agents\n* Presence of bleeding diathesis or coagulation disorders\n* Infection at the injection site or local skin lesions preventing block application",true,"6 Months","16 Years",{"count":54,"type":22},36,"1 Day","This prospective clinical study aims to compare the postoperative analgesic efficacy of the ultrasound-guided transversalis fascia plane block (TFPB) and the transversus abdominis plane (TAP) block in pediatric patients undergoing laparoscopic surgery. Effective and long-lasting postoperative analgesia is essential for patient and parental satisfaction in pediatric anesthesia. With recent advances in ultrasound technology, regional anesthesia techniques have become increasingly utilized in pediatric practice.\n\nIn the TAP block, local anesthetic is injected between the internal oblique and transversus abdominis muscles, providing analgesia typically between Torachal vertebra 10 (T10) and Lumbar vertebra (L1) dermatomes. The transversalis fascia plane block, developed as a modification of this approach, targets the proximal portions of the T12 and L1 nerves by depositing local anesthetic between the transversus abdominis muscle and the transversalis fascia, potentially offering wider sensory coverage.\n\nThis study compares both blocks in terms of postoperative pain scores, duration of analgesia, and requirement for rescue analgesics in children undergoing laparoscopic surgery. The results are expected to contribute to the optimization of regional anesthesia techniques and improve pain management strategies in pediatric surgical patients.",[58,27,59,60,61],"Postoperative Analgesia","Transversalis Fascia Plane Block","Pediatric Surgical Procedures","Laparoscopic Abdominal Surgeries",[63,64,65,66,67],"transversus abdominis plane block","transversalis fascia plane block","pediatrics","laparoscopic abdominal surgery","postoperative analgesia","RECRUITING","2026-03-09",{"date":71,"type":35},"2026-03-10",{"date":73,"type":35},"2025-12-18",{"date":75,"type":22},"2026-06-15",{"name":77,"class":42},"Sakarya University",1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":101,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":115,"leadSponsor":117,"locationsCount":78},"100622848","peripheral-autonomic-block-bap-plus-transversus-abdominis-plane-block-tap-for-postoperative-analgesia-after-minimally-invasive-left-sided-colorectal-resection-baptap-100622848","NCT07388953","Peripheral Autonomic Block (BAP) Plus Transversus Abdominis Plane Block (TAP) for Postoperative Analgesia After Minimally Invasive Left-Sided Colorectal Resection (BAPTAP)","Peripheral Autonomic Block (BAP) Plus Transversus Abdominis Plane Block (TAP) for Postoperative Analgesia After Minimally Invasive Left-Sided Colorectal Resection (BAPTAP): A Randomized, Controlled, Double-Blind Trial","BAPTAP","Inclusion Criteria:\n\n* Elective laparoscopic left-sided colorectal resection\n* ASA physical status I-II\n* Ability to understand the study and sign informed consent\n\nExclusion Criteria:\n\n* Known allergy to study medications (e.g., local anesthetics)\n* Coagulation disorders\n* Pregnancy\n* Inability to understand or provide consent\n* Chronic pain on opioid therapy\n* BMI \\> 35 kg\u002Fm²","80 Years",{"count":89,"type":22},140,"INTERVENTIONAL",[92],"NA","Effective postoperative pain management is essential for enhanced recovery after laparoscopic colorectal surgery. This randomized, controlled, double-blind trial will compare conventional postoperative analgesia (intravenous medications plus surgical wound infiltration) with a locoregional strategy combining a peripheral autonomic block (inferior mesenteric and superior hypogastric plexuses) and a transversus abdominis plane (TAP) block. We hypothesize that the combined strategy (BAPTAP) reduces pain intensity and opioid consumption in the first 48 hours after Left-Sided Colorectal Resection.",[95,96,97,98,27,99,100],"Colorectal Cancer","Colorectal Surgery","Anesthesia","Autonomic Nerve Block","Pain Management","Post Operative Analgesia",[102,103,104,105,106,107,108,109,110],"colorectal surgery","Postoperative Pain","Peripheral Autonomic Block","Superior Hypogastric Plexus","Inferior Mesenteric Plexus","TAP Block","ERAS","Ropivacaine","Opioid-sparing Analgesia","2026-02-12",{"date":113,"type":35},"2026-02-13",{"date":111,"type":35},{"date":116,"type":22},"2027-07-05",{"name":118,"class":42},"Faculdade de Ciências Médicas de Minas Gerais",{"id":120,"slug":121,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":124,"acronym":4,"eligibilityCriteria":125,"healthyVolunteers":50,"sex":17,"minAge":18,"maxAge":126,"enrollmentInfo":127,"targetDuration":4,"studyType":90,"phases":129,"briefSummary":130,"conditions":131,"keywords":135,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":78},"100584827","comparison-the-analgesic-efficacy-of-ultrasonographic-bilateral-tap-and-anesthetic-infiltration-into-the-surgery-field-for-laparoscopic-unilateral-tep-herniorrhaphy-100584827","NCT06894420","Comparison the Analgesic Efficacy of Ultrasonographic Bilateral TAP and Anesthetic Infiltration Into the Surgery Field for Laparoscopic Unilateral TEP Herniorrhaphy","Comparison of Postoperative Analgesic Efficacy of Ultrasonographic Bilateral TAP (Transversus Abdominis Plane) Block and Anesthetic Infiltration Into Preperitoneal and the Surgical Field in Laparoscopic Unilateral TEP (Total Extraperitoneal) Herniorraphy","Inclusion Criteria:\n\n* Consenting patients,\n* She will undergo laparoscopic hernia repair surgery,\n* ASA-I-II,\n* Between the ages of 18 and 65,\n* No history of anticoagulant or antiaggregant drug use,\n* Regional anesthesia is not contraindicated and the anesthesiologist deems -appropriate for regional anesthesia,\n* Under general anesthesia and will undergo laparoscopic surgery,\n* Fully oriented and cooperative,\n* Unilateral inguinal hernia,\n* No previous surgery for inguinal hernia,\n* No incision in the lower abdomen,\n* Not using alcohol and drugs,\n* No preoperative pain and\n* Patients without symptoms of strangulated hernia will be included in the study.\n\nExclusion Criteria:\n\n* Patients without consent\n* Regional anesthesia is contraindicated,\n* Those who will undergo open abdominal surgery,\n* Not in the appropriate age range,\n* Chronic diseases such as uncontrolled DM and HT,\n* Drug allergy,\n* Taking anticoagulant or antiaggregant drugs,\n* History of chronic analgesic use,\n* Presence of active infection in the area to be blocked,\n* Will not be able to comply with postoperative pain \u002FVAS follow-up,\n* Patients with ASA-III-IV,\n* Patients with bilateral inguinal and scrotal hernias,\n* Patients who have been previously operated for inguinal hernia and have an incision in the lower abdomen,\n* Those with a history of alcohol and drug abuse\n* Preoperative pain and\n* Those with symptoms of strangulated hernia will not be included in this study.","65 Years",{"count":128,"type":22},60,[92],"Laparoscopic inguinal hernia repair is a common surgical procedure, but postoperative pain management remains a challenge. This prospective, randomized study aims to compare the analgesic efficacy of preperitoneal and surgical site anesthetic infiltration with ultrasound-guided bilateral transversus abdominis plane (TAP) block in patients undergoing laparoscopic unilateral total extraperitoneal (TEP) herniorrhaphy. Sixty patients will be randomly allocated into two groups: Group-I will receive preperitoneal and surgical site infiltration with bupivacaine, while Group-II will receive ultrasound-guided bilateral TAP block with bupivacaine. The primary outcomes will be postoperative pain scores assessed using the visual analog scale (VAS) and additional analgesic requirements. Secondary outcomes will include postoperative hospital stay duration and cost-effectiveness. Demographic data, ASA scores, comorbidities, and operation times will be recorded. Postoperative pain will be managed with a multimodal approach, including paracetamol and NSAIDs. Rescue analgesia will be provided with intravenous paracetamol. Statistical analysis will be performed using t-tests, ANOVA, Wilcoxon-Mann-Whitney tests, and chi-square tests, as appropriate. This study aims to determine the optimal and most beneficial method for postoperative pain management and patient comfort following laparoscopic inguinal hernia repair.",[132,133,134,27,58],"Laparoscopic Surgery","Herniorrhaphy","Inguinal Hernia Unilateral",[136,137,67,27],"Laparoscopic surgery","Inguinal hernia","2025-09-19",{"date":140,"type":35},"2025-09-24",{"date":142,"type":35},"2025-09-04",{"date":144,"type":22},"2026-06-30",{"name":146,"class":147},"Başakşehir Çam & Sakura City Hospital","OTHER_GOV",{"id":149,"slug":150,"hasResults":11,"nctId":151,"briefTitle":152,"officialTitle":152,"acronym":4,"eligibilityCriteria":153,"healthyVolunteers":50,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":154,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":155,"conditions":156,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":159,"lastUpdatePostDateStruct":160,"startDateStruct":162,"completionDateStruct":164,"leadSponsor":166,"locationsCount":78},"100581046","comparison-of-the-efficacy-of-transversus-abdominis-plane-block-and-erector-spinae-plane-block-in-postoperative-analgesia-management-after-abdominoplasty-100581046","NCT06845215","Comparison of the Efficacy of Transversus Abdominis Plane Block and Erector Spinae Plane Block in Postoperative Analgesia Management After Abdominoplasty","Inclusion Criteria:\n\n* Patients who underwent abdominoplasty and received TAP or ESP blocks for postoperative analgesia, followed by monitoring with IV PCA.\n\nExclusion Criteria:\n\n* Cases in which IV PCA was not used, VAS scoring was unavailable, or complications occurred.",{"count":128,"type":22},"Introduction: Abdominoplasty involves the removal of excess skin and fat from the abdominal region, rectus sheath plication, and umbilical transposition. The number of cosmetic abdominoplasty procedures has been steadily increasing in recent years. Due to extensive tissue manipulation and large incisions during surgery, postoperative pain has become a significant concern. Studies report that up to 80% of patients experience postoperative pain; however, fewer than half of these patients receive adequate analgesia. Improving postoperative pain control has been shown to facilitate early mobilization, reduce hospital length of stay, lower healthcare costs, and enhance patient satisfaction. Therefore, ensuring effective postoperative analgesia has become a critical aspect of patient management.\n\nTransversus abdominis plane (TAP) block and erector spinae plane (ESP) block are peripheral nerve block techniques that can be used as part of a multimodal analgesia approach for postoperative pain management after abdominoplasty. In this study, we aimed to compare the effects of TAP and ESP blocks on postoperative pain in patients undergoing abdominoplasty.\n\nAim\u002FHypothesis:\n\nH0: There is a significant difference in the analgesic efficacy between ultrasound-guided ESP and TAP blocks in postoperative pain management after abdominoplasty.\n\nH1: There is not a significant difference in the analgesic efficacy between ultrasound-guided ESP and TAP blocks in postoperative pain management after abdominoplasty.\n\nMaterials and Methods: Our study was designed as a retrospective analysis. Patient records and hospital database will be reviewed to identify all patients who underwent abdominoplasty and received TAP block or ESP block for postoperative analgesia. Demographic data including age, gender, weight, height, body mass index (BMI) and American Society of Anesthesiologists (ASA) classification, as well as comorbidities and medications used will be recorded on case report forms. The type of block performed (TAP or ESP) and postoperative pain scores obtained from pain assessment forms using the Numerical Rating Scale (NRS) at 0, 2, 4, 6, 12 and 24 hours postoperatively will be documented. In addition, data from the patient-controlled analgesia (PCA) device will be recorded, including number of doses demanded (DEM) and number of doses delivered (DEL). Other parameters such as additional analgesic requirements, postoperative nausea and vomiting, itching and patient satisfaction will also be recorded.",[157,103,27,158],"Abdominoplasty","Erector Spinae Plane Block","2025-06-12",{"date":161,"type":35},"2025-06-15",{"date":163,"type":35},"2025-02-20",{"date":165,"type":22},"2025-07-20",{"name":167,"class":147},"Ankara Ataturk Sanatorium Training and Research Hospital",{"id":169,"slug":170,"hasResults":11,"nctId":171,"briefTitle":172,"officialTitle":173,"acronym":4,"eligibilityCriteria":174,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":126,"enrollmentInfo":175,"targetDuration":4,"studyType":90,"phases":177,"briefSummary":178,"conditions":179,"keywords":182,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":78},"100587780","comparison-of-postoperative-analgesic-efficacy-of-transversus-abdominis-plane-block-tap-and-modified-thoracoabdominal-nerve-block-m-tapa-100587780","NCT06932835","Comparison of Postoperative Analgesic Efficacy of Transversus Abdominis Plane Block (TAP) and Modified Thoracoabdominal Nerve Block (M-TAPA)","Comparison of Postoperative Analgesic Efficacy of Transversus Abdominis Plane Block (TAP) and Modified Thoracoabdominal Nerve Block (M-TAPA) in Patients Undergoing Laparoscopic Cholecystectomy","Inclusion Criteria:\n\n* 18 to 65 years old\n* American Society of Anesthesiologists (ASA) physical status I-II-III\n* Body mass index 18 to 30 kg\u002Fm2\n* Elective laparoscopic cholecystectomy surgery\n\nExclusion Criteria:\n\n* Under 18 and over 65\n* ASA score IV and above\n* Advanced co-morbidity\n* History of bleeding diathesis\n* Patient refusing the procedure\n* Chronic opioid or analgesic use\n* Patients who will operate under emergency conditions\n* Block injection site infection\n* Known allergy to local anesthetics\n* Pregnancy",{"count":176,"type":22},80,[92],"Laparoscopic cholecystectomy is a frequently performed surgical procedure and is considered the gold standard for treating symptomatic gallstone disease. Although laparoscopic cholecystectomy is considered minimally invasive, it can cause moderate to severe pain in the postoperative period. Poorly controlled early postoperative pain can impair recovery quality and increase the risk of postoperative pulmonary complications as a risk factor for chronic pain development. Multimodal analgesia, including opioids, is used to limit pain following laparoscopic cholecystectomy. However, opioid treatment may lead to side effects such as postoperative nausea and vomiting (PONV), respiratory depression, and constipation.\n\nNerve blocks provide better pain control, reduce opioid consumption in the postoperative period, and offer advantages such as fewer side effects and a lower risk of pulmonary and cardiac complications.\n\nIn our clinic, a multimodal analgesia approach is preferred for patients undergoing laparoscopic cholecystectomy. In addition to intravenous analgesic agents, peripheral nerve blocks are administered based on patient preference (for all eligible and consenting patients).\n\nThis study aims to compare the postoperative analgesic efficacy of the Transversus Abdominis Plane (TAP) Block and the Modified Thoracoabdominal Nerve Block with a Pericostal Approach (M-TAPA) in patients undergoing laparoscopic cholecystectomy. Standard analgesic methods are applied to patients who do not consent to peripheral nerve block administration.",[180,27,181],"Laparoskopic Cholecystectomy","Modified Thoracoabdominal Nerve Block (M-TAPA)",[183,184,185],"remifantanile conception","acute pain","Postoperatif pain","2025-06-03",{"date":188,"type":35},"2025-06-04",{"date":190,"type":35},"2025-06-02",{"date":192,"type":22},"2026-04-21",{"name":194,"class":147},"Ankara Etlik City Hospital",{"id":196,"slug":197,"hasResults":11,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":4,"eligibilityCriteria":201,"healthyVolunteers":11,"sex":202,"minAge":18,"maxAge":4,"enrollmentInfo":203,"targetDuration":4,"studyType":90,"phases":205,"briefSummary":206,"conditions":207,"keywords":209,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":213,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":219,"locationsCount":4},"100582098","the-effect-of-tap-block-on-maternal-infant-bonding-100582098","NCT06858891","The Effect of TAP Block on Maternal-Infant Bonding","The Effect of Transversus Abdominis Plane Block on Maternal-Infant Bonding in Cesarean Sections Performed Under Spinal Anesthesia","Inclusion Criteria:\n\n* 18 aged or older patients,\n* Agree to participate in the study\n* Pregnant women without any maternal or fetal pathology during the pregnancy.\n\nExclusion Criteria:\n\n* \\\u003C18 age\n* Deny to participate in the study\n* maternal or fetal pathology during the pregnancy\n* Allergy to local anesthetics\n* local ingection at block side","FEMALE",{"count":204,"type":22},132,[92],"Cesarean delivery is a common surgical procedure that is typically performed under spinal anesthesia. Postoperative pain management has a significant impact on both the mother's physical recovery and the quality of maternal-infant bonding. The quality of maternal-infant bonding is influenced by various factors, including postoperative pain, early mobilization, initiation of breastfeeding, stress, psychological status, and hormonal balance. Studies have reported that adequate postoperative pain management, early breastfeeding, and early mobilization have positive effects on maternal-infant bonding.\n\nTransversus abdominis plane (TAP) block is a regional anesthesia technique known for its efficacy in controlling postoperative pain. Bilateral TAP block performed after cesarean section has been associated with lower pain scores, reduced analgesic consumption, and shorter hospital stays. However, its impact on maternal-infant bonding has not been fully elucidated.\n\nThis study aims to investigate the effect of bilateral TAP block on maternal-infant bonding in women undergoing cesarean section under spinal anesthesia.",[208,27],"Cesarean Section",[210,27,211],"cesarean section","Maternal-Infant Bonding","2025-03-04",{"date":214,"type":35},"2025-03-06",{"date":216,"type":22},"2025-03-10",{"date":218,"type":22},"2025-04-10",{"name":220,"class":42},"Adiyaman University Research Hospital"]