[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"trauma-and-emergency-care\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:trauma-and-emergency-care":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100633743","delayed-fluids-in-hemorrhagic-shock-due-to-severe-injuries-100633743",false,"NCT07530653","Delayed Fluids in Hemorrhagic Shock Due to Severe Injuries.","Delayed Resuscitation in Hemorrhagic Shock Due to Severe Injuries of the Torso in Low-resource Facilities of Latin America.","PERMIT-LATAM","Inclusion Criteria:\n\n* Major injuries.\n* ISS \\>15.\n* Hypotension with a systolic blood pressure below 90 mmHg.\n* No previous hospital care.\n* Older than 16 years.\n\nExclusion Criteria:\n\n* Brain injuries.\n* Pregnancy.\n* Drowning.\n* Burns.","ALL","18 Years","100 Years",{"count":21,"type":22},716,"ESTIMATED","OBSERVATIONAL","This study will provide information on the quality of care in hemorrhagic shock of severe injuries in a limited resource facility of Latin America, the strategies of fluid resuscitation, and outcomes.",[26,27,28],"Trauma and Emergency Care","Shock,Hemorrhagic","Intravenous Fluid Therapy",[30,31,32,33,34,35,36,37,38],"Severe Trauma","Hemorrhagic shock","Non-compresible torso injuries","Delayes resuscitation","Permissive hypotension","IV fluids","Low-resource settings","Latin America","Trauma systems","NOT_YET_RECRUITING","2026-05-25",{"date":42,"type":43},"2026-05-28","ACTUAL",{"date":45,"type":22},"2026-10-01",{"date":47,"type":22},"2028-11-30",{"name":49,"class":50},"Hospital Departamental de Villavicencio","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100612355","early-phase-1-early-intravenous-magnesium-sulfate-and-its-impact-on-cerebral-vasospasm-in-traumatic-subarachnoid-hemorrhage-100612355","NCT07252505","Early Intravenous Magnesium Sulfate and Its Impact on Cerebral Vasospasm in Traumatic Subarachnoid Hemorrhage","Inclusion Criteria:\n\n* Patients aged between eighteen to sixty five years Diagnosed with tSAH on Head Computed Tomography(CT)within 24 hours of trauma.\n* Both Genders are included Indication for endovascular or microsurgical treatment plan\n\nExclusion Criteria:\n\n* Aneurysmal or spontaneous SAH Sever hepatic dysfunction.\n* Known hypersensitivity to magnesium sulfate\n* Renal disease with glomerular filtration rate\\\u003C15 ml\u002Fmin.\n* pregnancy","65 Years",{"count":60,"type":22},50,"INTERVENTIONAL",[63],"EARLY_PHASE1","Subarachnoid hemorrhage (SAH) is a clinical phenomenon caused by the abrupt rupture and bleeding of blood vessels at the surface or base of the brain, which can occur for a number of reasons. As a result, the subarachnoid membrane receives direct blood flow. SAH is a debilitating neurological disorder with high morbidity and mortality. Despite advancements in medicine and surgical care, patients who survive their first bleeding event are at high risk for secondary sequelae, including delayed cerebral ischemia (DCI) and cerebral vasospasm (CV)\n\nCV denotes a temporary, self-resolving constriction of the intracranial arteries that occurs several days after an SAH. This phenomenon is closely linked to clinical deterioration resulting from DCI, affecting up to 30% to 40% of patients. DCI is a significant clinical event that typically manifests 3 to 14 days after the initial bleeding and is characterized by subsequent neurological deterioration. These complications can lead to poor functional outcomes and long-term disability\n\nSubarachnoid hemorrhage is classified into aneurysmal subarachnoid hemorrhage (aSAH) and Traumatic SAH (tSAH). TSAH has been described as an adverse prognostic factor leading to progressive neurological deterioration and increased morbidity and mortality. Traumatic subarachnoid hemorrhage is caused by head injuries from events like falls, motor vehicle crashes, and blows to the head, which damage blood vessels within the skull. The injury itself is the primary cause, leading to the brain being hit against the skull and tearing these blood vessels",[26],"2025-11-24",{"date":68,"type":43},"2025-11-26",{"date":70,"type":22},"2025-11",{"date":72,"type":22},"2027-10",{"name":74,"class":50},"Assiut University"]