[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"trauma-including-fractures\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:trauma-including-fractures":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,51,77,115,148,178,212],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100608942","mortality-of-trauma-in-the-intensive-care-unit-100608942",false,"NCT07208110","Mortality of Trauma in the Intensive Care Unit.","Factors Associated With Mortality by Trauma in the Intensive Care Unit in Villavicencio, Colombia. A Trial Based on a Discharge Registry.","MOTRAM-ICU-COL","Inclusion Criteria:\n\n* Admitted to the intensive care unit.\n\nExclusion Criteria:\n\n* None.","ALL","15 Years","100 Years",{"count":21,"type":22},500,"ESTIMATED","OBSERVATIONAL","In this study, it was planned to establish the factors associated with severe trauma discharged from the intensive care unit and mortality. A cross-sectional trial will be conducted to review the ICU discharge database at a two-year interval to review records of trauma admissions patients and compare them with other types of admissions. Participant institutions are general hospitals (public and private) from the Colombian Orinoco region. the prevalence of admission by trauma will also be determined.",[26,27,28,29,30],"Trauma (Including Fractures)","Trauma ICU Patients","Trauma Injury","Trauma Patients in ICU","Trauma Patients",[32,33,34,35,36,37],"Trauma","Wounds and Injuries","Intensive Care Units","Trauma Registry","Low-Middle Income Countries","Colombia","RECRUITING","2026-05-25",{"date":41,"type":42},"2026-05-27","ACTUAL",{"date":44,"type":42},"2026-01-30",{"date":46,"type":22},"2028-12",{"name":48,"class":49},"Hospital Departamental de Villavicencio","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100640036","phase-3-tru-vu-wrist-positioning-aid-multi-center-implementation-within-nlhs-100640036","NCT07580976","Tru-Vu Wrist Positioning Aid Multi-Center Implementation Within NLHS","Inclusion Criteria:\n\n* Must be 18 years of age or older\n* Must be proficient in English (reading\u002Fwriting)\n* Must have been referred for wrist imaging at one of the following healthcare centers: Health Sciences Center (St. John's, NL), Bonne Bay Health Center (Norris Point, NL), or Labrador Health Center (Happy Valley-Goose Bay, NL).\n\nExclusion Criteria:\n\n* Incapable of providing informed consent","18 Years",{"count":59,"type":22},1800,"INTERVENTIONAL",[62],"PHASE3","This study has two primary aims: 1) to determine whether a novel wrist x-ray positioning aid can be implemented within 3 different healthcare centers in Newfoundland and Labrador, and 2) to determine the ability of the tool to improve patient positioning in wrist x-rays. It will also learn about the number of repeat x-rays required with or without the use of the tool and radiographer confidence. The main questions it aims to answer are:\n\n1. Will the implementation of the Tru-Vu differ between an urban health center, rural clinic, and remote regional hospital?\n2. Can the Tru-Vu improve the positioning procedure for radiographers performing wrist x-rays, resulting with more useful x-rays.\n\nResearchers will compare x-rays before and after the implementation of the tool as well as between centers.\n\nTechnologist participants will:\n\n* Use the tool during the positioning procedure for wrist x-rays.\n* Provide feedback regarding tool use and perceived implementation barriers and facilitators.",[26,65],"Arthritis","NOT_YET_RECRUITING","2026-05-13",{"date":69,"type":42},"2026-05-18",{"date":71,"type":22},"2026-06-14",{"date":73,"type":22},"2027-09-01",{"name":75,"class":49},"Western University",3,{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":88,"conditions":89,"keywords":94,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":50},"100630810","renal-and-hepatic-abnormal-doppler-patterns-in-trauma-100630810","NCT07492511","Renal and Hepatic Abnormal Doppler Patterns in Trauma","Renal and hEpatiC abnoRmal dopplEr pAtterns iN Trauma: a Multicentre Prospective Observational Study","RECREANT","Inclusion Criteria:\n\n* Age 18-65 years;\n* Admission within 24h from traumatic injury;\n* ISS \\>15\n\nExclusion Criteria:\n\n1. Age \\\u003C18 or \\>65;\n2. Known heart failure (NYHA ≥II);\n3. Chronic kidney disease (any stage) or chronic RRT;\n4. Chronic respiratory disease needing home O₂ or ventilation;\n5. Radiological evidence of vascular or parenchymal renal injury on trauma CT precluding reliable Doppler assessment","65 Years",{"count":87,"type":22},350,"The goal of this observational study is to learn about renal and hepatic blood flow abnormalities detected by bedside ultrasound in adult patients admitted to the intensive care unit (ICU) following major trauma.\n\nThe main questions it aims to answer are:\n\n* How reliably can trained operators measure renal Doppler and venous congestion scores (RDRI and VExUS) across different hospitals?\n* How common are abnormal kidney and liver blood flow patterns in major trauma patients during the first 72 hours of ICU admission?\n* Are these abnormal patterns associated with acute kidney injury or the need for mechanical ventilation?\n\nParticipants admitted to ICUs or high-dependency units (HDUs) with major trauma (Injury Severity Score \\>15) will undergo non-invasive bedside ultrasound assessments at admission and at 24, 48, and 72 hours. No additional treatments or interventions will be given as part of this study. Kidney function will also be checked at 6 months after hospital discharge.",[26,30,90,91,92,93],"Kidney Disease","Hypovolemia","Hypervolemia","Kidney Failure",[95,96,97,98,99,100,101,102,103,104],"VEXUS","trauma","kidney injury","kidney failure","Venous congestion","renal perfusion","Renal Doppler resistive index","major trauma","Hemodynamic phenotyping","ICU","2026-03-19",{"date":107,"type":42},"2026-03-25",{"date":109,"type":42},"2026-03-01",{"date":111,"type":22},"2030-06-30",{"name":113,"class":114},"Azienda Usl di Bologna","OTHER_GOV",{"id":116,"slug":117,"hasResults":11,"nctId":118,"briefTitle":119,"officialTitle":120,"acronym":121,"eligibilityCriteria":122,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":123,"enrollmentInfo":124,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":126,"conditions":127,"keywords":133,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":146,"locationsCount":50},"100629532","negative-pressure-wound-therapy-as-a-predictor-of-persistent-pain-after-war-related-trauma-100629532","NCT07475897","Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma","Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma: A Prospective Cohort Study","NPWT-Pain Stud","Inclusion Criteria:\n\n* age ≥18 years\n* war-related trauma (blast injury, fragmentation injury, gunshot wound, burn injury, or crush injury)\n* traumatic soft tissue injury requiring surgical management\n* ability to provide informed consent\n* availability for follow-up assessments\n\nExclusion Criteria:\n\n* chronic pain in the same anatomical region prior to injury\n* severe cognitive impairment preventing pain assessment\n* inability to communicate or complete questionnaires\n* refusal to participate\n* incomplete baseline data or loss to follow-up","60 Years",{"count":125,"type":22},150,"War-related trauma frequently causes complex soft tissue injuries that require repeated surgical treatment and advanced wound management techniques such as Negative Pressure Wound Therapy (NPWT). Although NPWT is widely used to promote wound healing and prepare wounds for reconstruction, its relationship with long-term pain outcomes remains unclear.\n\nThis prospective cohort study aims to investigate whether the use of NPWT after war-related trauma is associated with an increased risk of persistent post-traumatic pain six months after injury. Adult patients with traumatic soft tissue injuries requiring surgical management will be enrolled and followed for six months.\n\nIn addition to NPWT exposure, the study will evaluate several early clinical predictors of chronic pain, including acute pain intensity, number of surgical debridements, suspected nerve injury, and mechanism of trauma. Understanding these predictors may help clinicians identify high-risk patients early and develop targeted strategies for pain prevention and rehabilitation after severe trauma.",[128,129,130,26,131,132],"Phantom Limb Pain After Amputation","Chronic Pain Due to Injury","Postoperative Pain","Amputation Stump","Amputation Stump; Infection",[134,135,136,137,138,139],"Negative Pressure Wound Therapy","War-related trauma","Post-traumatic pain","Neuropathic pain","Chronic pain after trauma","Soft tissue injury","2026-03-16",{"date":142,"type":42},"2026-03-18",{"date":144,"type":22},"2026-03-15",{"date":144,"type":22},{"name":147,"class":49},"Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)",{"id":149,"slug":150,"hasResults":11,"nctId":151,"briefTitle":152,"officialTitle":153,"acronym":4,"eligibilityCriteria":154,"healthyVolunteers":155,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":156,"targetDuration":4,"studyType":60,"phases":158,"briefSummary":160,"conditions":161,"keywords":165,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":173,"completionDateStruct":174,"leadSponsor":176,"locationsCount":50},"100617116","5-minute-hot-trauma-ct-rates-of-detection-study-100617116","NCT07314437","5 Minute 'HOT' Trauma CT Rates Of Detection Study","Randomised Trial (With Integrated Pilot) Evaluating Whether a Standardised Approach, Educational Package (Including Checklist) Improve Recognition of Major Life-threatening Injuries in the Hot Reporting of Trauma Scans","Inclusion Criteria:\n\n* Medical professionals involved in trauma image review.\n* This includes clinicians who are emergency department doctors, radiologists and other specialties.\n* Non-radiologist clinicians will be participating completing the hot reports, radiologists will be evaluating their submissions and assessing their accuracy.\n\nExclusion Criteria:\n\n* Unable to review CT imaging due to lack of previous experience or disability that prevents them from doing so.\n* Under 18 years old.\n* Not a medical professional or clinician.",true,{"count":157,"type":22},300,[159],"NA","Many injured patients receive urgent CT imaging to identify major injury. CT imaging of trauma patients is often time critical and the accurate detection of life-threatening findings on this CT is essential. Often following a scan a radiologist is not immediately available to review the imaging, however other members of the trauma team have access to the imaging and may be in a position to provide a \"hot\" report. In this study we aim to demonstrate if an educational intervention with a checklist improves accuracy of the hot report.",[26,162,163,164],"Trauma Abdomen","Trauma Blunt","Trauma Centers",[32,166,167,168,169],"CT","Hot Report","Radiology","HOT-RODs","2026-01-08",{"date":172,"type":42},"2026-01-12",{"date":44,"type":22},{"date":175,"type":22},"2027-02-28",{"name":177,"class":49},"University Hospital Plymouth NHS Trust",{"id":179,"slug":180,"hasResults":11,"nctId":181,"briefTitle":182,"officialTitle":183,"acronym":184,"eligibilityCriteria":185,"healthyVolunteers":11,"sex":17,"minAge":186,"maxAge":4,"enrollmentInfo":187,"targetDuration":4,"studyType":60,"phases":189,"briefSummary":190,"conditions":191,"keywords":197,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":210,"locationsCount":50},"100613601","assess-the-efficacy-of-tailored-patient-information-and-voluntary-patient-managed-outpatient-digital-follow-up-i-pod-as-an-adjunct-to-standard-treatment-according-to-national-guidelines-in-the-national-trauma-plan-among-adult-trauma-patients-in-norway-100613601","NCT07268716","Assess the Efficacy of Tailored Patient Information and Voluntary Patient-managed Outpatient Digital Follow-up (I-POD) as an Adjunct to Standard Treatment According to National Guidelines in the National Trauma Plan Among Adult Trauma Patients in Norway.","A Randomized Controlled Clinical Trial to Assess the Efficacy of Tailored Patient Information and Voluntary Patient-Managed Outpatient Digital Follow-Up as an Adjunct to Standard Treatment According to National Guidelines in Adult Trauma Patients in Norway (The POSTRAUMA Trial).","POSTRAUMA","Inclusion Criteria:\n\n* 16 years or older\n* Fulfils the national criteria for TTA and admitted to HUS following trauma\n* Included in NTR database\n* Able to give informed consent\n\nExclusion Criteria:\n\n* 15 years or younger\n* Not included in NTR database\n* Deceased before discharge from the hospital.\n* Not able to give informed consent\n* Insufficient command of the Norwegian language\n* Foreign tourists or nationals\n* Suicide attempt or serious self-inflicted trauma\n* Serious psychiatric disorders or serious ongoing substance abuse","16 Years",{"count":188,"type":22},256,[159],"The POSTRAUMA trial is a clinical trial at The Regional trauma centre of Western Norway, Haukeland University Hospital.\n\nTrauma is the leading cause of death worldwide in patients aged 1-45 years. In Norway, approximately 10,000 patients are admitted to hospital annually due to trauma, with 66% being male. The mean age is 43 years for male and 48 years for female, indicating a relatively young patient population.\n\nWhile mortality rates are decreasing, a significant proportion of trauma survivors experience long-term disabilities, reduced quality of life, and difficulties in returning to work. These consequences impose substantial burdens on individuals, families, and society. Considering these issues, a shift in focus is needed-from survival alone to long-term functional recovery and quality of life after trauma.\n\nSevere trauma often requires long-term follow-up, both physically and psychosocially. Traditional follow-up can be fragmented and not tailored to individual needs. Digital patient monitoring and tailored information have the potential to improve patient pathways, but knowledge about how these are experienced by patients is limited.\n\nThe goal is to find out if Norwegian trauma patients who receive tailored patient information and patient-managed outpatient digital follow-up, in addition to standard treatment have:\n\n* Less disability\n* Return more often to work\n* Improved quality of life\n\nThe study population are Norwegian trauma patients, 16 years or older at date of inclusion, who are admitted to Haukeland University hospital (HUS) following trauma with trauma team activation. 256 patients will be included in this trial.\n\nParticipants will:\n\n* Answer a questionnaire at inclusion, one month, 6 months and 12 months.\n* Participants in the intervention group will be invited to digital outpatient follow up one month after the accident.\n* Some participants will be interviewed about how they experienced their trauma follow up.",[164,30,26,28,192,193,194,195,196],"Rehabilitation After Neurological or Orthopaedic Injuries","Rehabilitation","Return to Work","HRQOL (Health Related Quality Of Life)","EQ5D5L-VAS",[198,96,199,200,201,202],"multitrauma","rehabilitation","return to work","HRQOL","EQ5D","2025-12-16",{"date":205,"type":42},"2025-12-22",{"date":207,"type":22},"2026-03-02",{"date":209,"type":22},"2029-12-31",{"name":211,"class":49},"Haukeland University Hospital",{"id":213,"slug":214,"hasResults":11,"nctId":215,"briefTitle":216,"officialTitle":216,"acronym":4,"eligibilityCriteria":217,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":218,"targetDuration":4,"studyType":60,"phases":220,"briefSummary":221,"conditions":222,"keywords":225,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":229,"lastUpdatePostDateStruct":230,"startDateStruct":232,"completionDateStruct":234,"leadSponsor":236,"locationsCount":238},"100607820","assessment-of-the-feasibility-of-using-a-preoperative-surgical-fracture-analysis-tool-100607820","NCT07193524","Assessment of the Feasibility of Using a Preoperative Surgical Fracture Analysis Tool","Inclusion Criteria:\n\n* Age above 18\n* lower extremity fracture",{"count":219,"type":22},40,[159],"This study aims to evaluate a preoperative fracture analysis tool that uses 3D visualization and biomechanical modeling to assist surgeons in planning screw and plate fixation for complex tibial plateau fractures. By simulating different fixation strategies based on patient-specific CT data, the tool provides insights into construct stability, potentially improving surgical precision and reducing intraoperative uncertainty. The study also investigates the tool's feasibility within current clinical workflows without altering the standard of care.",[223,26,224],"Tibia Fractures","Surgical Planning",[226,227,224,228],"3D","Tibia fracture","Fracture Analysis","2025-09-24",{"date":231,"type":42},"2025-09-26",{"date":233,"type":42},"2025-09-10",{"date":235,"type":22},"2028-09",{"name":237,"class":49},"Brigham and Women's Hospital",2]