[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"traumatic-stress\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:traumatic-stress":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,54,81,146],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":4},"100625648","personalizing-mental-health-treatment-for-youth-and-families-100625648",false,"NCT07425366","Personalizing Mental Health Treatment for Youth and Families","Development of a Decision Support Tool for Culturally Adapting Mental Health Treatment to Improve Outcomes for Latine Youths","Inclusion Criteria:\n\n* Identify as Latino\n* Fluent in English or Spanish\n* 5-15 years old\n* Referred to individual psychotherapy with a participating clinician for a primary clinical concern involving anxiety, depression, trauma, or disruptive behaviors\n\nExclusion Criteria:\n\n\\-","ALL","5 Years","15 Years",{"count":20,"type":21},64,"ESTIMATED","INTERVENTIONAL",[24],"NA","Incompatibility between evidence-based treatments (EBTs) and the cultural values, practices, and minoritized experiences of Latine youth and families contributes to racial-ethnic disparities in mental health treatment engagement and consequently mental health outcomes. The proposed study aims to develop and pilot a novel tool - the Culturally Responsive Assessment, Formulation, and Treatment Tool (CRAFTT) - for helping clinicians decide whether, when, and how to culturally adapt EBTs for individual Latine youth clients and thereby improve the cultural compatibility of EBTs for this underserved population. Completion of this study will result in a functional decision support tool designed to improve the quality and effectiveness of mental health services for Latine youths and promote mental health equity.",[27,28,29,30],"Anxiety","Traumatic Stress","Disruptive Behavior","Depression",[32,33,34,35,36,37,38,39,40,41],"child","anxiety","depression","traumatic stress","disruptive behavior","community mental health","National Institute of Mental Health","treatment adaptation","treatment fidelity","decision support tool","NOT_YET_RECRUITING","2026-02-18",{"date":45,"type":46},"2026-02-20","ACTUAL",{"date":48,"type":21},"2027-01",{"date":50,"type":21},"2028-09",{"name":52,"class":53},"University of Oregon","OTHER",{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":16,"minAge":61,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":65,"conditions":66,"keywords":67,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":4},"100622977","community-health-worker-implementation-of-transdiagnostic-evidence-based-mental-health-intervention-for-spanish-speaking-latine-parents-100622977","NCT07390630","Community Health Worker Implementation of Transdiagnostic Evidence-based Mental Health Intervention for Spanish-speaking Latine Parents","Community Health Worker Implementation of Transdiagnostic Evidence-based Treatment in Spanish","INCLUSION criteria for PATIENT participants are:\n\n* 18 years or older\n* Identifies as Latine\n* Is a caregiver to a child 18 years or younger old living in the same household\n* Preference for Spanish services\n* Symptom scores in the moderate range for depression, anxiety, and\u002For PTSD (based on Computerized Adaptive Tests for Mental Health (CAT-MH))\n\nEXCLUSION criteria for PATIENT participants:\n\n* Presence of mania symptoms in the mild range or higher (based on CAT-MH responses)\n* Presence of psychosis symptoms in mild range or higher (based on CAT-MH responses)\n* Active suicidal ideation (based on CAT-MH responses)\n* Depression, anxiety, or PTSD symptoms in the severe range (based on CAT-MH responses)\n* Currently receiving psychotherapy services","18 Years",{"count":63,"type":21},52,[24],"The goal of this clinical trial is to learn if it is doable for community health workers (CHWs) to deliver a mental health intervention to Spanish-speaking Latine parents experiencing anxiety, depression, and\u002For traumatic stress. The main questions it aims to answer are (1) Is it doable for CHWs to deliver the mental health intervention and for Latine parents to participate in the intervention, and (2) does the CHW-delivered intervention work in reducing Latine parents' mental health symptoms.\n\nResearchers will compare Latine parents receiving the intervention to Latine parents not receiving the intervention to see if the CHW-delivered intervention works to improve mental health symptoms.\n\nParticipants will:\n\n* Participate in up to 14 weekly 1-hour sessions of the mental health intervention delivered by a CHW. They will be randomized to receive the intervention immediately or after a 5-month delay.\n* Participants will complete questionnaires about their symptoms, family and child functioning, as well as about how doable, acceptable, and appropriate they found the intervention\n* Participants will also complete a recorded interview about their experience in the intervention",[30,27,28],[68,69,70,71],"community health workers","implementation science","feasibility","parent mental health","2026-01-28",{"date":74,"type":46},"2026-02-05",{"date":76,"type":21},"2027-02",{"date":78,"type":21},"2029-03",{"name":80,"class":53},"University of Illinois at Chicago",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":16,"minAge":61,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":22,"phases":90,"briefSummary":91,"conditions":92,"keywords":102,"overallStatus":135,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":145},"100587056","effectiveness-implementation-and-cost-of-cognitive-processing-therapy-in-prisons-100587056","NCT06923423","Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons","STRIDES2","Inclusion Criteria:\n\n* 18 years of age or older\n* Able to understand and speak English\n* Able to give informed consent\n* All items listed in \"Inclusion criteria for all participants\"\n* Be currently incarcerated in one of the prisons that have partnered as study sites\n* Have met criteria for a drug use disorder in the year prior to their current incarceration (≥ 2 symptoms on a DSM-5 drug use disorder checklist)\n* Have used drugs in the 30 days prior to their current incarceration\n* Have a history of traumatic event exposure\n* Endorse clinically significant posttraumatic stress symptoms (score ≥ 4 on the Primary Care PTSD Screen for DSM-5; PC-PTSD-5)\n* Expect to be incarcerated for at least long enough to complete CPT-CJ as it is being implemented at the particular site (i.e., anticipated to be \\~3 months, but will depend on dates associated with next available intervention group)\n* Expect to be released from prison within 12 months following the end of treatment (i.e., within \\~15 months of the pre-treatment assessment)\n* Willing to consent to randomization to treatment condition\n\nExclusion criteria for prisoners (additional requirements assessed during pre-treatment assessments or indicated by prison staff; will result in being withdrawn from the study prior to randomization by the PI):\n\n* Unable to provide any locator information for post-release assessments\n* Determined to be releasing sooner than would allow the individual to complete CPT-CJ\n* Determined to have an unavoidable scheduling conflict or facility restriction (e.g., disciplinary, medical) that would prevent participation in CPT-CJ. Of note, if the scheduling conflict or facility restriction is expected to resolve following the next round of randomization at the study site, the participant may be put on \"hold for next round\" status rather than withdrawn unless other exclusionary criteria would be met by that time (e.g., release).",{"count":89,"type":21},640,[24],"Addiction and trauma exposure are common among the 5.5 million people (1 in 47 adults) in the U.S. who are in prison or under supervision. About 85% of people in prison have a substance use disorder or are there for a drug-related crime, and many have experienced serious trauma before being incarcerated. Posttraumatic stress symptoms (PTSS) are often a result of trauma and are linked to more severe drug use, higher rates of relapse, and increased crime. PTSS and substance use disorder (SUD) each raise the chances of new arrests for people who are justice-involved, showing that addressing trauma and addiction could help reduce repeat offenses and the costs of incarceration. However, treatments for PTSS are rarely available in prisons, and there is little research on whether providing therapy for PTSS in prison can lower drug use, PTSS, or crime after release.\n\nThe goal of this clinical trial is to see if trauma-focused group therapy (CPT) provided while in prison, can help people after release from prison. The therapy has been adapted for use in prisons (CPT-CJ) and will be compared to trauma focused therapy delivered via a self-help workbook\n\nThis study will:\n\n* test whether a trauma-focused group therapy (CPT-CJ) can reduce post-incarceration drug and alcohol use, mental health issues, and drug-related crime, compared to trauma-focused self-help,\n* evaluate a strategy called implementation facilitation, which helps support the use of this therapy in prisons, and\n* measure the cost of the therapies and support strategies to help plan for future expansion.\n\nIncarcerated participants (N = 640; 50% female) will be enrolled from \\~10 prisons in \\~5 states, ensuring variability in population and setting characteristics. They will:\n\n* take surveys and answer questions up to 5 times (before starting treatment, right after getting treatment, right before leaving prison, 3 months after leaving prison and 6 months after leaving prison)\n* complete CPT group therapy or self-help therapy\n* provide urine samples 3 months and 6 months after leaving prison\n\nPrison stakeholders (e.g., prison staff, prison leadership, governmental officials; N = \\~15 per site) who will be purposively sampled based on their role in CPT-CJ implementation will also participate in some surveys.",[93,94,95,96,30,97,98,99,100,28,101],"PTSD - Post Traumatic Stress Disorder","PTSD and Alcohol Use Disorder","PTSD and Trauma-related Symptoms","Substance Use Disorder (SUD)","Mental Health","Trauma","Trauma Exposure","Traumatic Stress Disorder","Post Traumatic Stress Symptoms",[103,104,105,106,107,108,109,110,111,112,113,114,115,98,30,116,117,118,119,120,121,122,123,124,125,126,127,128,129,130,131,132,133,134],"Post traumatic Stress Disorder","Post traumatic Stress Symptoms","Substance Use","Substance Use Disorder","Cognitive Processing Therapy","Cognitive Processing Therapy for Criminal Justice Setting","Trauma focused self help","Facilitation","Implementation Facilitation","Implementation","Cost Estimation and Offsets","Drug Use Disorder","Alcohol Use Disorder","Adult","Incarcerated","Prison","Imprisonment","Intervention","Treatment Comparison","Acceptability","Feasibility","Budget Impact","Cost Estimate","Implementation Evaluation","Recidivism","Self Help","Workbook","Criminal Justice","Effectiveness","Evidence Based Intervention","CPT","CPT-CJ","RECRUITING","2026-01-20",{"date":138,"type":46},"2026-01-21",{"date":140,"type":46},"2025-07-07",{"date":142,"type":21},"2028-12",{"name":144,"class":53},"University of Arkansas",6,{"id":147,"slug":148,"hasResults":11,"nctId":149,"briefTitle":150,"officialTitle":151,"acronym":152,"eligibilityCriteria":153,"healthyVolunteers":11,"sex":16,"minAge":154,"maxAge":155,"enrollmentInfo":156,"targetDuration":4,"studyType":22,"phases":158,"briefSummary":159,"conditions":160,"keywords":162,"overallStatus":135,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":176},"100583574","problem-management-plus-with-emotional-processing-pmep-for-forcibly-displaced-youth-100583574","NCT06878092","Problem Management Plus With Emotional Processing (PM+EP) for Forcibly Displaced Youth","Feasibility and Acceptability of Problem Management Plus With Emotional Processing (PM+EP) for Forcibly Displaced Youth Living in Sweden","PM+EP","Inclusion Criteria:\n\n* 16 to 25 year old youth who arrived in Sweden in 2015 or later due to being forcibly displaced;\n* Elevated levels of psychological distress as determined through the Kessler-10 psychological distress scale (K10; K10 \\> 15);\n* Reduced levels of psychosocial functioning as measured by the WHO Disability Assessment Schedule (WHODAS 2.0; WHODAS 2.0 \\> 16);\n* Assessment and manual are available in their preferred language, including Swedish.\n\nExclusion Criteria:\n\n* An acute medical condition;\n* Imminent suicide risk;\n* Indication of psychotic disorders and substance-dependence;\n* Indication of severe cognitive or neurological impairment;\n* Receiving specialized mental health treatment;\n* In case of current psychotropic medication used: change in dosage during the past two months.","16 Years","25 Years",{"count":157,"type":21},60,[24],"The goal of this feasibility randomized controlled trial is to learn about the feasibility and acceptability of scalable psychological interventions in Sweden. It will also allow for a preliminary exploration of a novel modular addition targeting traumatic stress to Problem Management Plus (PM+), an evidence-based transdiagnostic psychological intervention for psychological distress.\n\nThe main question it aims to answer is whether PM+ and PM+ Emotion Processing (PM+EP) feasible and acceptable among forcibly displaced youth in Sweden?\n\nParticipants will be randomized to receive PM+, PM+EP, or treatment as usual. The two intervention arms consist of a weekly session for six weeks.\n\nAssessments will collect data on a variety of psychological symptoms, wellbeing, and service use throughout the duration of the study. Assessments will take place at baseline, 1-week post-intervention, and 3-weeks post-intervention.",[161,28],"Psychological Distress",[163,164,165,166],"psychological distress","scalable psychological interventions","forcibly displaced","common mental disorders","2025-06-26",{"date":169,"type":46},"2025-07-01",{"date":171,"type":46},"2024-06-01",{"date":173,"type":21},"2025-10",{"name":175,"class":53},"Karolinska Institutet",1]