[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"trigger-points\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:trigger-points":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,74,91],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100053218","effect-of-dry-needling-plus-vibration-on-myofascial-trigger-points-in-individuals-with-nonspecific-low-back-pain-100053218",false,"NCT06527339","Effect of Dry Needling Plus Vibration on Myofascial Trigger Points in Individuals With Nonspecific Low Back Pain","Acceptability and Effectiveness of Adding a Percutaneous Vibratory Stimulus to Dry Needling for the Treatment of Myofascial Trigger Points in Nonspecific Low Back Pain: A Randomized Controlled Trial.","Inclusion Criteria:\n\n1. Individuals with NSLBP: pain persisting for more than six weeks, located between the twelfth rib and the buttocks, and scoring at least 3 points on the Numeric Pain Rating Scale;\n2. Presence of MTrPs in any of the following muscles that are associated with low back pain (erector spinae muscles, longissimus, iliocostalis, multifidus, gluteus maximus, gluteus medius, and quadratus lumborum);\n3. Aged between 35-65 years: this population exhibits the highest prevalence of low back pain and consequently represents the greatest socio-economic impact on society;\n4. Having signed the informed consent form.\n\nExclusion Criteria:\n\n1. Diagnosis of specific pathologies associated with low back pain (e.g., herniated discs, neurological disorders);\n2. Any form of infiltration within the past 3 months;\n3. Having received any physiotherapy interventions in the lumbopelvic region within the past 4 weeks;\n4. History of surgical intervention in the lumbopelvic region;\n5. Use of anticoagulant or antiplatelet medications within the last week;\n6. Presence of systemic or local lumbar infections;\n7. Pregnancy;\n8. Fear of needles (belonephobia).","ALL","35 Years","65 Years",{"count":20,"type":21},36,"ESTIMATED","INTERVENTIONAL",[24],"NA","Low back pain is one of the most common health issues worldwide, and in most cases, this pain is nonspecific low back pain (NSLBP). NSLBP is characterized by the inability to determine the real source of the pain and commonly presents with myofascial trigger points (MTrPs) in the muscles related to the lumbar region.\n\nOne of the most widely used techniques for treating NSLBP by targeting MTrPs is dry needling (DN), a technique that involves inserting a needle to produce a mechanical effect capable of \"deactivating\" the MTrP and thereby alleviating its symptoms. However, some studies have concluded that other techniques are more effective than DN, such as percutaneous electrolysis (PE).\n\nWhen using the PE technique, it appears that adding a galvanic current enhances the effects of DN. Nonetheless, this poses a greater risk to the patient, as the galvanic current could damage nervous tissue if it comes into contact. For this reason, it is proposed to investigate whether other physical agents that are not electrical could enhance the effect of DN without increasing its risk. This is the case for vibration, a stimulus that has already been used successfully for the treatment of MTrPs, allowing us to investigate whether adding vibration to DN introduces therapeutic capabilities that:\n\n* Maintain or increase the effectiveness of DN in terms of pain and functional capacity.\n* Do not add risks for the patient, unlike PE.\n* Are less painful than DN and cause less post-needling pain than that generated after successive needle insertions with DN. Emphasizing these adverse effects is necessary since most clinical trials do not report these variables, which is fundamental for describing the safety of invasive techniques.\n\nFollowing this idea, the present project will analyze a new invasive therapy for the treatment of MTrPs: dry needling with vibratory stimulus (DN+V), for which the following hypotheses are proposed:\n\n* DN+V, instead of using an electrical stimulus like PE that could cause damage to some tissues, will apply vibration to the DN needles to increase the mechanical stimulus exerted on the MTrP, expecting greater benefits in terms of pain, functional capacity, muscle strength, and other variables of interest in individuals with NSLBP, and possibly requiring less treatment time than DN.\n* In DN, the repeated insertions and withdrawals of the needle in the MTrP provoke a hemorrhagic and inflammatory reaction that translates into hypersensitivity and microscopic tissue injury in the muscle, causing pain during treatment and post-needling pain for the following 24-32 hours. Another study showed that PE caused less post-needling pain than DN, which may be due to the fact that, unlike DN, it is common in PE to only perform a single puncture with each needle and not mobilize them.\n* The methodology for DN+V will be the same as for PE, with a single puncture and no needle manipulation, so it is expected that DN+V, being less invasive than DN, will reduce pain during treatment and post-needling pain compared to that generated by DN. There are studies that support this hypothesis, concluding that needle manipulation in DN produces greater post-needling pain than DN without needle manipulation.",[27,28,29,30],"Low Back Pain","Dry Needling","Trigger Points","Vibration",[32,33,34],"Non-specific low back pain","vibration dry needling","miofascial trigger points","NOT_YET_RECRUITING","2026-07-08",{"date":38,"type":39},"2026-07-13","ACTUAL",{"date":41,"type":21},"2026-09",{"date":43,"type":21},"2027-07",{"name":45,"class":46},"Universidad de Zaragoza","OTHER",2,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":73},"100633379","immediate-effect-of-dry-needling-on-calf-muscles-pain-pressure-thresholdsprint-speed-and-functional-performance-in-amateur-football-player-100633379","NCT07525921","Immediate Effect of Dry Needling on Calf Muscles Pain Pressure Threshold,Sprint Speed and Functional Performance in Amateur Football Player","Inclusion Criteria:\n\n* Amateur football players aged 18-25 years.\n\nParticipation in club-level football for at least one year.\n\nPresence of active myofascial trigger point in gastrocnemius or soleus confirmed by palpation.\n\nWillingness to participate and provide informed consent.\n\nExclusion Criteria:\n\n* History of calf muscle tear, fracture, or lower limb surgery.\n\nCurrent use of muscle relaxants or anti-inflammatory medication.\n\nKnown bleeding disorders or anticoagulant therapy.\n\nLocal infection, skin lesion, or contraindication to dry needling.\n\nNeurological or vascular disorders affecting lower limb function.","18 Years","25 Years",{"count":57,"type":21},60,[24],"This randomised single-blind trial will evaluate the immediate effect of a single session of dry needling versus sham needling on calf muscle myofascial trigger points among amateur football players aged 18-25 years. Primary and secondary outcomes are Pressure Pain Threshold (algometer), Sprint Speed (shuttle run test), and Functional Performance (single-leg hop). Outcomes will be measured immediately pre- and post-intervention. Data analysis will be performed in SPSS version 27 using paired and independent t-tests (p \\\u003C 0.05).",[61,29,62],"Myofascial Pain Syndromes","Gastrocnemius Muscle","RECRUITING","2026-04-06",{"date":66,"type":39},"2026-04-13",{"date":68,"type":39},"2025-08-29",{"date":70,"type":21},"2026-06-01",{"name":72,"class":46},"Foundation University Islamabad",1,{"id":75,"slug":4,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":22,"phases":79,"briefSummary":25,"conditions":80,"keywords":82,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":73},"100556610","RCT: Analysis of the Effectiveness on Pain in Individuals With Nonspecific Low Back Pain by Adding a Percutaneous Vibratory Stimulus to Dry Needling in the Treatment of MTrPs","Inclusion Criteria:\n\n* Individuals with nonspecific low back pain, defined as pain persisting for more than 3 months between the twelfth rib and the buttocks, registering a Numeric Pain Rating Scale (NPRS) score of 3 or higher prior to the intervention. Additionally, participants must meet the following criteria:\n* Presence of myofascial trigger points (PGMs) in any of the following muscles relevant to the project: erector spinae (longissimus and iliocostal), multifidus, gluteus maximus, gluteus medius, and quadratus lumborum. Detection of these PGMs will be conducted by a specialized physiotherapist.\n* Individuals aged 18 years or older, proficient in either Spanish or English. Participants who have provided informed consent by signing the consent form\n\nExclusion Criteria:\n\n* Diagnosis of lumbar pain associated with specific pathologies such as disc herniations or neurological disorders.\n* Recent infiltration therapy within the past 3 months.\n* Recent manual therapy, acupuncture, or dry needling interventions in the lumbopelvic region within the last 4 weeks.\n* Previous surgical intervention in the lumbopelvic region.\n* Leg length discrepancy (\\>1 cm).\n* Recent use of anticoagulant or antiplatelet medications within the last week.\n* Systemic or local infection in the lumbar region.\n* Pregnancy.\n* Needle phobia (belonephobia).",{"count":20,"type":21},[24],[27,28,81,29],"Electrolysis",[32,33,34],"2025-11-27",{"date":85,"type":39},"2025-12-04",{"date":87,"type":21},"2026-05",{"date":89,"type":21},"2026-12",{"name":45,"class":46},{"id":92,"slug":93,"hasResults":11,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":4,"eligibilityCriteria":97,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":18,"enrollmentInfo":98,"targetDuration":4,"studyType":22,"phases":99,"briefSummary":100,"conditions":101,"keywords":107,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":73},"100597449","efficacy-of-adding-greater-occipital-nerve-block-to-trigger-point-injection-in-patients-with-neck-pain-100597449","NCT07058636","Efficacy of Adding Greater Occipital Nerve Block to Trigger Point Injection in Patients With Neck Pain","Evaluation of the Efficacy of Adding Greater Occipital Nerve Block to Trigger Point Injection in Patients With Neck Pain and Upper Trapezius Trigger Points: A Single-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged between 18 and 65 years.\n* Diagnosed with myofascial pain syndrome (MPS) based on the major and minor criteria described by Travell and Simons (a diagnosis requires all 5 major and at least 1 minor criterion)\n* Presence of active trigger points in the upper trapezius muscle.\n* Patients with neck pain lasting longer than 3 months.\n* Pain intensity of ≥5 on the Visual Analog Scale (VAS).\n\nExclusion Criteria:\n\n* Elderly, pediatric, pregnant, postpartum, or breastfeeding individuals; patients in intensive care; unconscious individuals; or legally incapacitated persons.\n* Known allergy to local anesthetics used in trigger point injection (e.g., lidocaine, bupivacaine) or to other drugs used (e.g., corticosteroids).\n* Patients with bleeding disorders (e.g., hemophilia, thrombocytopenia) or those currently on anticoagulant therapy.\n* Presence of active infection at or near the injection site, or any systemic infection; impaired skin integrity.\n* Patients with psychiatric disorders that may interfere with treatment response or affect study outcomes.\n* Patients with severe neurological or cardiovascular disorders, or with uncontrolled diabetes.\n* Patients with cervical disc pathologies with radiculopathy.\n* History of receiving shoulder injection, trigger point injection, dry needling, manual therapy, or electrotherapy within the past 3 months.\n* History of cervical or shoulder surgery.\n* Patients diagnosed with adhesive capsulitis, rotator cuff tendinopathy, or shoulder impingement syndrome.\n* Diagnosis of fibromyalgia.\n* Presence of active trigger points in other back muscles.",{"count":57,"type":21},[24],"Study Title:\n\nEvaluation of the Effectiveness of Adding Greater Occipital Nerve Block to Trigger Point Injection in Patients with Neck Pain Due to Upper Trapezius Trigger Points: A Single-Blind Randomized Controlled Trial\n\nPurpose of the Study:\n\nThis study aims to evaluate whether adding a Greater Occipital Nerve (GON) block to the standard trigger point injection treatment provides better pain relief and improves daily function in patients with neck pain caused by trigger points in the upper trapezius muscle. Trigger points are small, sensitive spots in muscles that can cause significant pain and discomfort. While both trigger point injections and GON blocks are common treatments for neck and head pain, it is not yet clear if combining these two methods offers better results.\n\nWhy is this study important? Neck pain related to trigger points in the upper trapezius muscle is a frequent problem, but there is limited research on the effectiveness of combining trigger point injections with GON blocks. This study will provide important information on whether the combination therapy can reduce pain more effectively and improve patients' quality of life and ability to perform daily activities.\n\nWho can participate?\n\nAdults aged 18 to 65 years old\n\nDiagnosed with myofascial pain syndrome (MAS) based on specific clinical criteria, including the presence of trigger points in the upper trapezius muscle\n\nExperiencing neck pain lasting longer than 3 months\n\nPain intensity rated 5 or higher on a scale of 0 to 10\n\nWho cannot participate?\n\nPregnant or breastfeeding women, children, elderly people, unconscious or critically ill patients\n\nPatients with allergies to local anesthetics or steroids\n\nIndividuals with bleeding disorders or infections near the injection site\n\nPatients with serious psychiatric or neurological diseases, or other medical conditions that may affect study results\n\nThose who have recently received similar treatments or surgery for neck or shoulder problems\n\nStudy Design and Procedures:\n\nThe study will include 60 patients meeting the criteria, randomly assigned to two groups using a balanced randomization method.\n\nGroup A will receive only trigger point injections into the upper trapezius muscle using a mixture of lidocaine and saline solution.\n\nGroup B will receive both trigger point injections and an ultrasound-guided GON block, which involves injecting a combination of local anesthetics and steroid near the greater occipital nerve to reduce pain signals.\n\nBoth groups will receive the same home exercise program focusing on stretching and strengthening neck muscles to support recovery. Patients will be encouraged to perform these exercises regularly and will be followed up weekly by phone to check their progress.\n\nThe doctor assessing patients' progress will not know which treatment the patient received, to ensure unbiased results.\n\nAssessments:\n\nPatients will be evaluated at three different times: before treatment, 1 week after treatment, and 4 weeks after treatment. Assessments include:\n\nPain intensity and quality (using Visual Analog Scale and McGill Pain Questionnaire)\n\nNeck disability and ability to perform daily activities (Neck Disability Index)\n\nQuality of life (Nottingham Health Profile)\n\nNeck joint movement and position sense (using clinical tests with special equipment)\n\nPosture evaluation (measuring head position using photography)\n\nExpected Outcomes:\n\nThe main goal is to determine if the combined treatment of trigger point injection plus GON block is more effective than trigger point injection alone in reducing pain, improving neck function, and enhancing quality of life.\n\nDuration and Follow-Up:\n\nThe study is planned to last 12 months. Patients will be closely monitored during and after treatment to ensure safety and to collect necessary data.\n\nPotential Benefits and Risks:\n\nParticipants may experience pain relief and improved function if the combined treatment is effective. Risks include mild discomfort or side effects related to injections, which will be minimized by experienced medical staff.",[102,103,104,29,105,106],"Neck Pain","Myofacial Pain Syndrome","Trigger Point Pain, Myofascial","Upper Trapezius Trigger Points","Cervicogenic Headache",[108,109,110,111,112],"neck pain","myofascial pain syndrome","trigger point injection","ultrasound guided occipital nerve block","upper trapezius trigger point","2025-07-01",{"date":115,"type":39},"2025-07-10",{"date":117,"type":39},"2025-04-03",{"date":119,"type":21},"2026-04",{"name":121,"class":122},"Ankara Etlik City Hospital","OTHER_GOV"]