[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"typically-developing-children\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:typically-developing-children":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100636543","repetitive-transcranial-magnetic-stimulation-on-motor-function-and-meta-plasticity-in-cerebral-palsy-tms-eeg-study-100636543",false,"NCT07567053","Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Cerebral Palsy: TMS-EEG Study","6-Hz Primed Low and High-Frequency Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Children With Cerebral Palsy: TMS-EEG Study","Inclusion Criteria (CP):\n\n* Aged 6 - 20 years,\n* A confirmed diagnosis of CP by a specialized professional (pediatric neurologist, PM\\&R physician, neonatal developmental specialist, or neonatologist) is a prerequisite for participation,\n* Classified as high functioning (Level I, II, or III) according to the Gross Motor Function Classification System (GMFCS),\n* Age-appropriate ability to understand and comply with study procedure throughout the entire duration of the study,\n* Preserved vision and hearing (with or without correction).\n\nInclusion Criteria (TD):\n\n* Aged 6 - 20 years\n* Age-appropriate ability to understand and comply with study procedure throughout the entire duration of the study,\n* Preserved vision and hearing (with or without correction).\n\nExclusion Criteria (CP):\n\n* Syndromic or genetic brain-related associations,\n* History of major trauma or brain surgery,\n* Inability to remain still,\n* History of Epilepsy,\n* Severe coexisting sickness or illness unrelated to CP or unstable medical conditions such as pneumonia,\n* Modified Ashworth Scale: Shoulder, elbow, and wrist scores more than 3,\n* Limb contractures caused by any other injury except CP,\n* Severe movement disorders that prevent intentional limb movements, such as choreoathetosis, or ballismus,\n* Contraindications for rTMS include non-removable metallic objects close to a coil and implanted electronic devices, such as cochlear implants and pacemakers.\n\nExclusion Criteria (TD):\n\n* Syndromic or genetic brain-related associations,\n* History of major trauma or brain surgery,\n* Inability to remain still,\n* History of Epilepsy,\n* Severe coexisting sickness or illness unrelated to CP or unstable medical conditions such as pneumonia,\n* Limb contractures caused by injury,\n* Severe movement disorders that prevent intentional limb movements, such as choreoathetosis, or ballismus,\n* Contraindications for rTMS include non-removable metallic objects close to a coil and implanted electronic devices, such as cochlear implants and pacemakers.",true,"ALL","6 Years","20 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","This project examines the use of repetitive transcranial magnetic stimulation (rTMS) as a therapeutic approach to improve motor function in children with cerebral palsy (CP). By applying 6-Hz primed low and high-frequency rTMS and measuring brain responses through TMS-EEG, the study aims to enhance neural plasticity and motor recovery. The goal is to promote faster rehabilitation and reduce long-term healthcare needs.",[28,29],"Cerebral Palsy","Typically Developing Children",[28,31,32,33,34,35,36],"CP","TMS","repetitive Transcranial Magnetic Stimulation","Transcranial Magnetic Stimulation","rTMS","TMS-EEG","NOT_YET_RECRUITING","2026-05-12",{"date":40,"type":41},"2026-05-14","ACTUAL",{"date":43,"type":22},"2026-05-01",{"date":45,"type":22},"2030-06-01",{"name":47,"class":48},"Cook Children's Health Care System","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":63,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":49},"100630339","task-specific-maximal-strength-and-motor-fatigability-during-daily-activities-of-the-arms-and-hands-in-typically-developing-children-100630339","NCT07486388","Task-specific Maximal Strength and Motor Fatigability During Daily Activities of the Arms and Hands in Typically Developing Children","Inclusion Criteria:\n\n* Age between 7 and 18 years\n* Sufficient understanding of the Dutch language to comprehend and perform the test procedures (also applicable to the parents\u002Flegal guardians)\n\nExclusion Criteria:\n\n* Upper limb movement problems within the past 6 months\n* Trauma to the upper limb within the past 6 months","7 Years","18 Years",{"count":59,"type":22},75,"OBSERVATIONAL","The aim of this study is to measure task-specific maximal strength and motor fatigability during functional daily activities involving the upper limbs in typically developing children. The focus is on determining the test-retest reliability of these measurements. In addition, the results are compared with existing data from children with cerebral palsy (CP). Through this comparison, we aim to gain insight into the motor limitations experienced by children with CP when performing everyday tasks.",[29],[64,65,66],"Motor fatigability","Strength","Upper limbs","RECRUITING","2026-03-17",{"date":70,"type":41},"2026-03-20",{"date":72,"type":41},"2025-11-05",{"date":74,"type":22},"2026-07",{"name":76,"class":48},"Hasselt University"]