[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"umbilical-hernia-repair\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:umbilical-hernia-repair":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100629583","evaluating-the-efficacy-of-suture-mesh-vs-planar-mesh-in-ventral-hernia-treatment-100629583",false,"NCT07476560","Evaluating the Efficacy of Suture Mesh vs. Planar Mesh in Ventral Hernia Treatment","Mesh Matters: Evaluating the Efficacy of Suture Mesh vs. Planar Mesh in Ventral Hernia Treatment - a Randomized, Blinded Multicenter Study","MeMa","Inclusion Criteria:\n\n* Ventral hernia (maximum size 3 × 3 cm) measured with Ultrasound or CT.\n* Participants must be eligible for surgical repair using either mesh-suture or planar mesh\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years.\n* Acute (emergent) operation.\n* Pregnancy.\n* Women with plans for future pregnancies.\n* Withdrawal of informed consent during admission.","ALL","18 Years",{"count":20,"type":21},280,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to investigate whether mesh-suture affects wound complication rates, patient-reported quality of life, and operation time in adult patients undergoing surgery for small ventral hernias.\n\nThe main questions it aims to answer are:\n\nDoes mesh-suture reduce wound complication rates compared to planar mesh? Does mesh-suture improve patient-reported quality of life(QoL) and affect operation time compared to planar mesh?\n\nComparison group:\n\nResearchers will compare standard treatment with planar mesh to the interventional treatment with mesh-suture to see whether mesh-suture leads to fewer complications, better quality of life, and shorter operation time.\n\nParticipants will:\n\nBe randomized to receive either planar mesh or mesh-suture during hernia repair surgery.\n\nUndergo standardized preoperative assessment, including baseline data and QoL scoring.\n\nAttend a postoperative visit on day 7-13 for wound inspection and ultrasound. Complete QoL assessments at 90 days (telephone follow-up). Have operation time recorded and medical records reviewed for readmissions within 90 days.",[27,28,29],"Abdominal Wall Hernia","Umbilical Hernia Repair","Epigastric Hernia Repair","RECRUITING","2026-03-12",{"date":33,"type":34},"2026-03-17","ACTUAL",{"date":36,"type":34},"2026-01-05",{"date":38,"type":21},"2032-12-31",{"name":40,"class":41},"Regionshospital Nordjylland","OTHER_GOV",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":71},"100604951","the-papyrus-study-permanent-vs-absorbable-sutures-in-primary-repair-of-umbilical-hernias-a-multicentre-single-blind-non-inferiority-randomized-controlled-trial-100604951","NCT07156188","The PAPYRUS Study: Permanent vs. Absorbable Sutures in PrimarY Repair of Umbilical HerniaS: A Multicentre, Single-blind, Non-inferiority, Randomized Controlled Trial","PAPYRUS","Inclusion Criteria:\n\n1. Elective surgery for primary umbilical hernia with a defect ≤ 2 cm measured clinically or radiographically\n2. Age 19 years or older\n3. Patient able to give oral and written informed consent\n\nExclusion Criteria:\n\n1. Umbilical hernia defect \\> 2 cm measured clinically, radiologically, or intraoperatively with ruler\n2. Multiple defects\n3. Incisional hernia: prior hernia in area of operation\n4. Recurrent umbilical hernia\n5. Epigastric hernia\n6. Secondary operation performed simultaneously\n7. Pregnancy\n8. Infected wounds\n9. Acute operation (incarcerated or strangulated hernia)\n10. BMI ≥ 35 kg\u002Fm\\^2\n11. Ascites or liver cirrhosis\n12. Peritoneal dialysis\n13. Immunosuppression\n14. Connective tissue disorder\n15. Patient deemed unfit for primary repair at time of surgery based on surgeon discretion at time of operation (e.g. poor tissue quality or unexpected operative finding)\n16. Defect is made in the umbilical skin or skin incision extended beyond paraumbilical incision (e.g. sigma or midline extended incision)",{"count":51,"type":21},914,[24],"Umbilical hernias can be found in over a quarter of the population and comprise of 15% of hernia repairs performed in Canada. While mesh repair is commonly used for larger hernias, smaller hernia defects are often closed with sutures alone. While non-absorbable sutures may have greater tensile strength, the use of absorbable sutures has been found to reduce the risk for wound infection and improve healing. The objective of this multi-centre, nationwide randomized controlled study is to determine whether there is a difference in hernia recurrence when the repair is completed with absorbable polydioxanone suture versus permanent polypropylene suture. The study will also explore post-operative complications and quality of life. Recruitment will take place over 5 years with follow-up at the 30-day, 12-month and 24-month mark following surgery. The results of this trial will be directly applicable to national and international hernia guidelines and will impact the care of thousands of patients.",[55,28],"Hernia Surgery",[57,58,59],"Umbilical hernia","Hernia repair surgery","Suture use","NOT_YET_RECRUITING","2025-09-27",{"date":63,"type":34},"2025-09-30",{"date":65,"type":21},"2026-01-01",{"date":67,"type":21},"2030-12-31",{"name":69,"class":70},"University of British Columbia","OTHER",5]