[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"undernutrition\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:undernutrition":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,13,0,[8,49,82,113,139,170,199,227,254,280,303,327,352],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100643436","randomized-evaluation-of-voucher-interventions-for-value-and-effectiveness-revive-in-philippines-100643436",false,"NCT07640594","Randomized Evaluation of Voucher Interventions for Value and Effectiveness (REVIVE) in Philippines","REVIVE","Inclusion Criteria:\n\n* Households enrolled in the REVIVE study sample drawn from Listahanan 3-eligible low-income households\n* Residency within selected study clusters in the study municipalities\n* Household consent to participate in the study and all survey components\n* Availability of a primary respondent (meal planner or primary food preparer) willing to participate in household interviews\n* For individual dietary assessment components: presence of at least one woman of reproductive age (15-49 years) and\u002For at least one child under five years of age, where applicable\n\nExclusion Criteria:\n\n* Households unwilling or unable to provide informed consent\n* Households not residing within the designated study clusters at the time of baseline data collection\n* Inability to complete core survey modules due to communication barriers or other conditions preventing reliable data collection","ALL","0 Months","99 Years",{"count":20,"type":21},5320,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to evaluate whether revised food voucher programs, combined with nutrition education sessions, can improve food security, dietary quality, nutrition knowledge, and nutritional outcomes among low-income households in the Philippines. Researchers will compare different monthly voucher amounts-Philippine Peso (PhP) 3,000, PhP 5,000, and PhP 8,000-with a no-voucher control group to determine which approach is most effective.\n\nThe main questions the study aims to answer are:\n\n* Do food vouchers improve household food security, reduce hunger, and improve dietary quality and nutrient intake?\n* Do larger voucher amounts lead to greater improvements in nutrition and health outcomes?\n* Does enhanced nutrition education improve nutrition knowledge and healthy eating practices?\n\nParticipants will:\n\n* Receive either a monthly food voucher or no voucher, depending on study group assignment\n* Attend nutrition education and Social and Behavior Change Communication (SBCC) sessions if assigned to a voucher group\n* Complete household interviews on food consumption, household expenditures, food security, and nutrition knowledge\n* Participate in dietary assessments and anthropometric measurements for women and children under 5 years of age",[27,28,29,30],"Food Insecurity","Undernutrition","Diet Quality","Nutrition Knowledge",[32,33,34,35],"Food Vouchers","Social and Behavior Change Communication","Cluster-Randomized Controlled Trial","Philippines","RECRUITING","2026-06-06",{"date":39,"type":40},"2026-06-10","ACTUAL",{"date":42,"type":40},"2026-04-29",{"date":44,"type":21},"2027-03-30",{"name":46,"class":47},"International Food Policy Research Institute","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":64,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":81},"100627693","effectiveness-of-small-quantity-vs-medium-quantity-lipid-based-nutrient-supplements-for-prevention-of-undernutrition-in-children-6-12-months-100627693","NCT07451951","Effectiveness of Small-Quantity vs Medium-Quantity Lipid-Based Nutrient Supplements for Prevention of Undernutrition in Children 6-12 Months","Effectiveness of Small-Quantity vs Medium-Quantity Lipid-Based Nutrient Supplements for Prevention of Undernutrition in Children Aged 6-12 Months: An Individually Randomized, Parallel-Group, Non-Inferiority Trial","Inclusion Criteria:\n\n* Children aged 6 months (26 weeks) to 7 months and 15 days (33 weeks) with weight-for-length z-score (WLZ) ≥ -2 standard deviation (SD) and mid-upper arm circumference (MUAC) ≥125 mm, born to mothers who are beneficiaries of the Benazir Income Support Programme and registered with the Benazir Nashonuma Programme (BNP) at any point during their pregnancy.\n* Permanent residents of the selected districts, with no plan to relocate or migrate within the next 6 months.\n* Written informed consent provided by the child's caregivers.\n\nExclusion Criteria:\n\n* Children with moderate acute malnutrition (MAM), defined as WLZ ≥ -3 to \\\u003C -2 SD, or MUAC ≥115 mm to \\\u003C125 mm.\n* Children with severe acute malnutrition (SAM), defined as WLZ \\\u003C -3 SD or MUAC \\\u003C115 mm or presence of bilateral pitting edema, who require therapeutic feeding.\n* Children with known congenital anomalies, chronic illness, or conditions affecting growth or feeding (for example, cerebral palsy or congenital heart disease).\n* Children already enrolled in any nutritional supplementation other than BNP or another clinical trial.\n* Children whose families will be unwilling to provide informed consent, or likely to be unavailable for follow-up.",true,"26 Weeks","33 Weeks",{"count":60,"type":21},980,[24],"Nutrition is essential for a child's growth, brain development, and protection from disease. While breastmilk provides the best nutrition for young infants, children older than six months may not get all the nutrients they need from breastmilk and regular foods alone. For this reason, some children receive special nutrient supplements to support healthy growth.\n\nLipid-based nutrient supplements (LNS) are one type of supplement that provides important vitamins and minerals. These supplements are used in many countries to help prevent undernutrition in young children. In Pakistan, the government social safety net program currently provides medium-quantity LNS to children starting at six months of age. However, it is not known whether a smaller-quantity LNS could provide similar benefits for children in this age group from under-resourced communities that have limited access to nutritious foods.\n\nThe goal of this trial is to learn whether small-quantity lipid-based nutrient supplements (SQ-LNS) work as well as medium-quantity lipid-based nutrient supplements (MQ-LNS) in preventing undernutrition in children aged six to twelve months.\n\nThe main questions this study aims to answer are:\n\n* Does SQ-LNS work as well as MQ-LNS in supporting healthy growth, including reducing stunting, wasting, and underweight?\n* Does SQ-LNS work as well as MQ-LNS in reducing anemia?\n\nResearchers will compare SQ-LNS and MQ-LNS to see if SQ-LNS is as good as MQ-LNS in preventing undernutrition.\n\nParticipants will:\n\n* Receive either SQ-LNS or MQ-LNS once daily for 6 months\n* Have their length, weight and mid-upper arm circumference (MUAC) measured monthly\n* Have their blood tested for anemia at the start and end of supplementation",[28],[65,66,67,68,69,70,71],"Stunting","Wasting","Anemia","Underweight","Small-quantity lipid-based nutrient supplement","Child nutrition","Medium-quantity lipid-based nutrient supplement","2026-05-29",{"date":74,"type":40},"2026-06-02",{"date":76,"type":40},"2026-02-26",{"date":78,"type":21},"2027-03-31",{"name":80,"class":47},"Aga Khan University",2,{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":56,"sex":16,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":22,"phases":94,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":48},"100639597","effectiveness-of-positive-deviancehearth-in-treating-uncomplicated-moderate-acute-malnutrition-in-children-6-59-months-in-mymensingh-division-bangladesh-100639597","NCT07591064","Effectiveness of Positive Deviance\u002FHearth in Treating Uncomplicated Moderate Acute Malnutrition in Children 6-59 Months in Mymensingh Division, Bangladesh","The Effectiveness of Positive Deviance\u002FHearth (PDH), a Local Dietary Approach, to Treat Uncomplicated Moderate Acute Malnutrition (MAM) in Children 6-59 Months in Mymensingh, Bangladesh","PD\u002FHearth MAM","Inclusion Criteria:\n\n* Children 6-52.9 months at Baseline. This is so that children are 6-59 months by end of study (6-7 months from baseline)\n* Children with MAM (WHZ\u002FWLZ \\\u003C-2 and ≥-3 and\u002For MUAC \\\u003C125mm and ≥115mm)\n* No Medical Complications (passes IMCI screening questions)\n* No oedema\n* Child does not deteriorate to SAM (WHZ\u002FWLZ\\\u003C-3 and\u002For MUAC\\\u003C115mm) because child should be referred to health centre\n* Caregiver refuses to receive age-appropriate immunization, Vitamin A and deworming minimum 2 weeks before PDH begins\n* Child is not planning to live outside the study area routinely for more than 2 weeks during the 3 months of the study\n* Written\u002FOral consent is given by Parent\u002FCaregiver to participate in the study\n\nExclusion Criteria:\n\n* Child is not between 6-52 months of age at Baseline\n* Child does not meet the inclusion criteria for WHZ\u002FWLZ and\u002For MUAC; (WHZ\u002FWLZ \\\u003C-2SD and ≥-3SD and\u002For MUAC \\\u003C125mm and ≥115mm);\n* Child has oedema;\n* Child has medical complications and\u002For does not pass the IMCI screening including fever, nausea\u002Fvomiting, acute respiratory illness (refer to Study Protocol V2.0, 19 Feb 2026);\n* Deteriorates to SAM and must be removed from the study and referred to the health centre for specially formulated food (SFF) treatment;\n* Refuses to receive minimum 2 weeks before the intervention begins, age-appropriate immunization and Vitamin A and deworming in the past 6 months;\n* Child lives outside the study area routinely or will be outside of the study area for more than 2 weeks in the upcoming 3 months\n* Parent\u002FCaregiver unable or unwilling to attend PDH from start;\n* Parent\u002FCaregiver does not provide written or oral consent to screen for the trial;\n* Parent\u002FCaregiver does not provide informed consent for the study; and\n* any other reason.","6 Months","59 Months",{"count":93,"type":21},400,[24],"The goal of this clinical trial (cluster randomized controlled trial) is to learn whether a Positive Deviance\u002FHearth (PDH) intervention can effectively treat moderate acute malnutrition (MAM) and reduce relapse compared to standard care in children aged 6-59 months diagnosed with MAM in Bangladesh. The main questions it aims to answer are:\n\n* Does the PDH intervention improve recovery rates among children with MAM?\n* Does the PDH intervention reduce relapse to MAM or progression to severe acute malnutrition (SAM) after recovery?\n\nResearchers will compare communities receiving the PDH intervention to communities receiving standard nutrition care (e.g., usual counseling or supplementary feeding programs) to see if PDH leads to better nutritional recovery and sustained outcomes.\n\nParticipants will:\n\n* Take part in a 12-day \"Hearth\" nutrition education program where caregivers prepare and feed children nutrient-dense meals using local foods\n* Receive 2 weeks of home follow-up visits by volunteers after the Hearth sessions, along with ongoing growth monitoring and counseling twice per month\n* Undergo periodic anthropometric assessments (weight, height\u002Flength, Mid-upper arm circumference (MUAC)) at key time points",[97,28,66],"Moderate Acute Malnutrition (MAM)",[99,100,101,102],"Moderate acute malnutrition (MAM)","Children","relapse","positive deviance\u002Fhearth","NOT_YET_RECRUITING","2026-05-08",{"date":106,"type":40},"2026-05-15",{"date":108,"type":21},"2026-05-16",{"date":110,"type":21},"2026-12-17",{"name":112,"class":47},"World Vision US",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":119,"eligibilityCriteria":120,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":121,"targetDuration":4,"studyType":22,"phases":123,"briefSummary":124,"conditions":125,"keywords":127,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":48},"100590786","tuberculosis-in-rural-and-malnourished-populations-100590786","NCT06971952","Tuberculosis in Rural and Malnourished Populations","Closing the Tuberculosis Diagnosis Gap in Rural and Malnourished Populations","TB-RAMP","Inclusion Criteria:\n\n* Index person\u002Fpeople diagnosed with drug sensitive pulmonary tuberculosis disease (PWTB) and starting TB treatment within 2 months of enrollment, of any age.\n* Index PWTB are eligible if they reside within the catchment area of Haydom Lutheran Hospital (HLH), and\n* Index PWTB intend to receive TB care at a participating study site.\n* Index PWTB (or their parent or guardian if index PWTB are \\\u003C18 years) and head of household (if different from index PWTB) are able and willing to provide informed consent.\n\nExclusion Criteria:\n\n* Inability to provide informed consent, or assent when applicable.\n* Residing or receiving TB care outside of the catchment area of study sites\n* Prior completion of TB screening procedures for all household members.",{"count":122,"type":21},360,[24],"Background: Tuberculosis (TB) remains a large public health threat in Tanzania with an estimated incidence of 195 per 100,000 people in 2022 and 36% of cases going undiagnosed. Nutritional and financial barriers combine to compound the burden of TB in Tanzania and many other high burden countries.\n\nObjectives: In this study, we aim to evaluate the effect and cost-effectiveness of conditional cash transfer added to the current facility-based approach to improve TB screening among household contacts (HHCs) of index people diagnosed with TB disease (PWTB) in rural Tanzania; and characterize the prevalence of undernutrition among HHCs of index PWTB and quantify the effect of undernutrition severity on the progression to active TB disease.\n\nMethods: In this prospective, interventional cohort study we plan to enroll 360 PWTB and their households within 2 months of TB treatment initiation. The duration of the study is 3 years in total: 2-year enrollment period, divided equally between the current standard of care phase and the added conditional cash transfer phase. All participating households will be visited 2 months after enrollment to complete TB screening for all HHCs and perform anthropometric measurements, and then followed a 2-year period to evaluate for incident TB disease among HHCs.\n\nData analysis: The proportion of households completing TB screening procedures for all HHCs during phase 1 will be compared to that during phase 2 using a chi-square test to evaluate the effect of conditional cash transfer on completion of HHC TB screening. A similar approach will be used to compare proportions of HHCs diagnosed with active TB disease based on nutritional status. We will use regression and Bayesian modeling to quantify the effect of demographic, nutritional and socioeconomic predictors on completion of HHC TB screening and the incidence of TB disease among HHCs to prioritize higher risk subgroup for TB prevention effort.\n\nImpact: Successful completion of this proposal will informTB programs in many high burden countries with implementable interventions that can be scaled in rural communities to prioritize TB prevention efforts to the HHCs at the highest risk of developing TB disease",[126,28],"Tuberculosis (TB)",[128,129,28],"Tuberculosis","Active case finding","2026-05-01",{"date":132,"type":40},"2026-05-05",{"date":134,"type":40},"2025-09-01",{"date":136,"type":21},"2030-09-01",{"name":138,"class":47},"University of Virginia",{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":4,"eligibilityCriteria":145,"healthyVolunteers":11,"sex":16,"minAge":146,"maxAge":147,"enrollmentInfo":148,"targetDuration":4,"studyType":22,"phases":150,"briefSummary":151,"conditions":152,"keywords":157,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":81},"100635438","effects-of-high-calorie-diets-vs-high-calorie-formulas-on-weight-gain-in-children-with-congenital-heart-disease--100635438","NCT07552688","\"Effects of High-Calorie Diets VS High-Calorie Formulas on Weight Gain in Children With Congenital Heart Disease \"","\"Effects of High-Calorie Diet vs High-Calorie Formula on Weight Gain and Clinical Outcomes Among Children With Congenital Heart Disease\"","Inclusion Criteria:\n\n* Children aged 1 to 5 years.\n* Diagnosed with congenital heart disease (confirmed by echocardiography).\n* Underweight (weight-for-age below the 10th percentile).\n* Medically stable and eligible for oral or enteral feeding.\n* Informed consent obtained from a parent.\n\nExclusion Criteria:\n\n* Children with genetic syndromes known to affect growth (e.g., Down syndrome).\n* Children with gastrointestinal conditions impairing nutrient absorption.\n* Children who had cardiac surgery within the last 4 weeks.\n* Presence of severe organ failure (renal, hepatic, etc.).\n* Children on parenteral nutrition.\n* Families unlikely to adhere to follow-up or dietary instructions.","1 Year","5 Years",{"count":149,"type":21},75,[24],"This study is a randomized controlled trial designed to evaluate the effects of high-calorie diets and specialized nutritional formulas on weight gain and clinical outcomes in underweight children aged 1 to 5 years with congenital heart disease (CHD). Children with CHD often experience growth failure due to increased energy needs and feeding difficulties, which can negatively impact their recovery, development, and overall health.\n\nSeventy-five children will be randomly assigned to one of three groups: a control group receiving a standard diet, a group receiving a high-calorie diet made from energy-dense foods, and a third group receiving both the high-calorie diet and a specialized high-calorie pediatric formula. The study will measure changes in weight, appetite, feeding tolerance, and other growth indicators over an 8-week period. The goal is to determine whether enhanced nutritional support can improve weight gain and health outcomes in this high-risk population.",[153,154,155,156,28],"Weight Gain","Body Mass Index","Pediatric Nutrition","Congenital Heart Disease",[158,159,160,161],"BMI","Nutritional Status","Growth and Development","Pediatric Nursing","2026-04-24",{"date":42,"type":40},{"date":165,"type":21},"2026-04-17",{"date":167,"type":21},"2026-06-01",{"name":169,"class":47},"Aryan Najmadin Nasradin",{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":174,"acronym":175,"eligibilityCriteria":176,"healthyVolunteers":11,"sex":16,"minAge":146,"maxAge":177,"enrollmentInfo":178,"targetDuration":4,"studyType":22,"phases":180,"briefSummary":181,"conditions":182,"keywords":186,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":5},"100509320","the-effect-of-high-caloric-oral-nutritional-supplements-on-growth-and-development-of-malnourished-children-100509320","NCT05911893","the Effect of High Caloric Oral Nutritional Supplements on Growth and Development of Malnourished Children","EHCONSGDMC","Inclusion Criteria:\n\n* Aged 1-3 years\n* BMI for Age Z-score\\\u003C-2\n* Height-for-age z score\\\u003C-2\n* Total daily energy intake\\\u003C75% of recommended nutrient intake\n* The child's guardian is willing to participate in this study and sign an informed consent form.\n\nExclusion Criteria:\n\n* Chronic or severe infectious disease (e.g., chronic hepatitis, HIV or tuberculosis infection)\n* Certain congenital or genetic diseases affecting physical growth and development (congenital heart disease, Down's syndrome, infantile anorexia nervosa, etc.), malignancies and use of drugs (diuretics, appetite stimulants, steroids and growth hormones, etc.)\n* Severe gastrointestinal disorders (e.g., celiac disease, short bowel syndrome, inflammatory bowel disease, etc.)\n* Acute and chronic respiratory\u002Fdigestive tract infections within 2 weeks prior to enrollment\n* Allergy or contraindication to any of the ingredients in the high-energy total nutrition formula used in this study\n* Have used high-energy enteral nutrition preparations for the last 3 months","3 Years",{"count":179,"type":21},200,[24],"The goal of this clinical trial is to investigate the effect of high caloric oral nutritional supplements on body proportion, weight, linear growth pattern, neuropsychological development level and related health aspects (gut health, immune function, quality of life, etc.) in participants aged 1 to 3 years who are malnourished (underweight and wasting),as well as to evaluate the safety of applying high caloric oral nutritional supplements. Participants will receive nutritional education and daily high caloric oral nutritional supplements(experimental group),or will receive nutritional education and dietary instruction(control group).This study may provide data to support the development of clinical intervention strategies for malnourished Chinese children.",[183,184,185,28],"Malnutrition, Child","Malnourishment","Nutritional Deficiency",[187,188,189],"Oral Nutritional Supplements","Physique Growth","Neuropsychological Development","2026-03-16",{"date":192,"type":40},"2026-03-18",{"date":194,"type":40},"2024-06-17",{"date":196,"type":21},"2026-03-10",{"name":198,"class":47},"Children's Hospital of Chongqing Medical University",{"id":200,"slug":201,"hasResults":11,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":205,"eligibilityCriteria":206,"healthyVolunteers":56,"sex":16,"minAge":207,"maxAge":208,"enrollmentInfo":209,"targetDuration":4,"studyType":22,"phases":211,"briefSummary":212,"conditions":213,"keywords":215,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":218,"lastUpdatePostDateStruct":219,"startDateStruct":221,"completionDateStruct":223,"leadSponsor":225,"locationsCount":81},"100469153","finger-food-pleasure-at-your-fingertips-randomized-pilot-study-open-label-and-parallel-groups-100469153","NCT05389098","Finger Food, Pleasure at Your Fingertips: Randomized Pilot Study, Open-label and Parallel Groups","L'Alimentation Manger-mains, le Plaisir au Bout Des Doigts : Etude Pilote randomisée, en Ouvert et en Groupes parallèles","PLAID","Inclusion Criteria:\n\n* Male or female residents over 75 years old living in a Accommodation facility for dependent elderly people for at least 3 months\n* Presenting at least one of the following 3 criteria:\n\n  * Unintentional weight loss ≥ 5% in 1 month\n  * Involuntary weight loss ≥ 10% in 6 months or compared to the usual weight or compared to the weight at entry to the EHPAD\n  * Confirmed sarcopenia:\n\n    * Male (at least one of the 2 criteria):\n\n      * Dynamometer (kg): \\\u003C 27 AND calf circumference (cm): \\\u003C 31\n      * Impedancemetry: appendicular muscle mass index \\\u003C 20 kg OR appendicular muscle mass index \\\u003C 7 kg\u002Fm²\n    * Woman (at least one of the 2 criteria):\n\n      * Dynamometer (kg): \\\u003C 16 AND calf circumference (cm): \\\u003C 31\n      * Impedancemetry: appendicular muscle mass index \\\u003C 15 kg OR appendicular muscle mass index \\\u003C 5.5 kg\u002Fm²\n* Loss of autonomy according to the Tully scale \\\u003C 12\u002F18 with a score of 2 or 3 on the item \"Able to bite, chew, swallow without making false routes\"\n* Person having given free, informed and express consent\n* Person having an affiliation to a social security scheme\n\nExclusion Criteria:\n\n* Protected person: safeguard of justice\n* Swallowing disorder having a contra-indication to the texture of hand-eating meals.\n* Lack of motor skills in both hands\n* Specific diet: pleasure diet, salt-free, sugar-free, fiber-free, artificial nutrition\n* Wearer of a pacemaker","75 Years","120 Years",{"count":210,"type":21},30,[24],"Food is available in easy-to-grip bites that allow residents in care settings to use their fingers for food. This new way of eating can help limit weight loss, increase food intake, gain independence and improve the enjoyment of eating for residents.",[28,214],"Elderly Person",[28,214,216,217],"Nursing home","Nutrition","2025-11-18",{"date":220,"type":40},"2025-11-24",{"date":222,"type":40},"2023-08-03",{"date":224,"type":21},"2027-01-31",{"name":226,"class":47},"University Hospital, Tours",{"id":228,"slug":229,"hasResults":11,"nctId":230,"briefTitle":231,"officialTitle":232,"acronym":4,"eligibilityCriteria":233,"healthyVolunteers":11,"sex":16,"minAge":146,"maxAge":234,"enrollmentInfo":235,"targetDuration":4,"studyType":22,"phases":237,"briefSummary":238,"conditions":239,"keywords":242,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":245,"lastUpdatePostDateStruct":246,"startDateStruct":248,"completionDateStruct":250,"leadSponsor":252,"locationsCount":4},"100603467","nutritional-assessment-in-patient-of-mucopolysaccharide--100603467","NCT07136896","Nutritional Assessment in Patient of Mucopolysaccharide \"","Nutritional Assessment of Patient of Mucopolysaccharide","Inclusion Criteria:Confirmed diagnosis of mucopolysaccharidosis (any subtype) by enzymatic assay or genetic testing\n\nAge between 1 and 18 years\n\nStable clinical condition at time of enrollment\n\nInformed consent obtained from parent\u002Fguardian, and assent from child when applicable -\n\nExclusion Criteria:Presence of other chronic conditions affecting growth or nutrition (e.g., untreated endocrine disorders, severe cardiac failure unrelated to MPS)\n\nAcute illness or hospitalization within the last 2 weeks prior to assessment\n\nPatients who received nutritional supplementation or dietary intervention within 3 months prior to enrollment that could affect baseline nutritional assessment\n\nRefusal or inability to comply with study assessments\n\n\\-","18 Years",{"count":236,"type":21},40,[24],"\" Nutritional assessment in patients of Mucopolysaccharide \"",[240,241,28],"Mucopolysaccharidosis (MPS)","Malnutrition (Calorie)",[243,244],"Caloric deficiency","Pediatric nutrition","2025-08-15",{"date":247,"type":40},"2025-08-22",{"date":249,"type":21},"2025-08-16",{"date":251,"type":21},"2026-08-30",{"name":253,"class":47},"Assiut University",{"id":255,"slug":256,"hasResults":11,"nctId":257,"briefTitle":258,"officialTitle":258,"acronym":259,"eligibilityCriteria":260,"healthyVolunteers":11,"sex":16,"minAge":234,"maxAge":4,"enrollmentInfo":261,"targetDuration":4,"studyType":22,"phases":263,"briefSummary":264,"conditions":265,"keywords":269,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":271,"lastUpdatePostDateStruct":272,"startDateStruct":274,"completionDateStruct":276,"leadSponsor":278,"locationsCount":48},"100586149","impact-of-nutritional-management-on-the-frailty-of-patients-waiting-for-liver-transplantation-via-the-lfi-tool-100586149","NCT06911619","Impact of Nutritional Management on the Frailty of Patients Waiting for Liver Transplantation (Via the LFI Tool)","LFI-PATH","Inclusion Criteria:\n\n* Patient aged ≥ 18 years\n* Patient registered on the waiting list for Hepatic Transplantation in the Transplantation center of the Croix Rousse Hospital (GHN), Hospices Civils de Lyon\n* Dated and signed an informed consent\n* Affiliated to a social security scheme or beneficiary of a similar scheme\n\nExclusion Criteria:\n\n* Patient hospitalized in intensive care\n* Patient with initial LFI test result \\\u003C to 3.2, that is considered as \"robust\".\n* Patient unable to perform LFI exercises (chronic or acute motor disability in lower or upper limbs)\n* Pregnant, parturient or lactating women\n* Persons deprived of liberty by a judicial or administrative decision\n* Persons under psychiatric care\n* Persons admitted to a health or social institution for purposes other than research\n* Adults subject to a legal protection measure (guardianship, curatorship)\n* Inability to understand protocol information\n* Subject participating in another interventional research including an ongoing exclusion period at inclusion",{"count":262,"type":21},210,[24],"Cirrhosis is a major public health issue responsible for about 15000 deaths each year. Liver transplantation (LT) remains the only curative treatment for decompensated cirrhosis. Decompensated cirrhotic patients awaiting LT are malnourished, sarcopenic and fragile. The evaluation of the nutritional status of these patients is complex because the anthropometric data that define undernutrition (weight variation, BMI) are often compromised by the presence of edema and ascites related to liver disease. It therefore seems appropriate to focus on the fragility and sarcopenia of the cirrhotic patient as a reflection of the nutritional status. In 2017, the American team of Lai et al. validated a Liver fraily index (LFI) score of frailty specific to cirrhotic patients waiting for LT. The LFI is composed of three simple physical tests (Grip test, chair lift test, and balance tests) performed at the patient's bedside, which results in a quantitative and reproducible frailty score. Frailty while waiting for LT is associated with an increase in mortality on the waiting list, independently of the MELD (Model for End stage Liver disease) score, which is a reflection of liver severity. About half of the patients who are candidates for LT will present an aggravation of their frailty while waiting for LT. To date, no study has reported the results of a nutritional intervention on the evolution of fragility in patients awaiting LT. The objective of our study is to evaluate the impact of a nutritional management and follow-up by a dietitian specialized in hepatology on the fragility of patients waiting for LT. This is a monocentric study, randomized in two parallel groups (an intervention group with nutritional follow-ups by a trained dietitian and a control group with follow-up by the reference hepatologist without specific dietary management by a dietician) in open. All patients enrolled on the LT list with an LFI \\> 3.2 (pre-frail and frail state) will be included in the study. It is planned to include 210 patients over a period of 24 months. The LFI will be measured for all patients (control group + intervention group) at 3 and 6 months, as part of their follow-up in the LT center. This study will also make it possible to correlate frailty with other parameters (severity of liver disease, access to LT).",[266,267,268,28],"Fragility","Cirrhosis","Hepatic Transplantation",[270,268,267],"nutrition","2025-07-01",{"date":273,"type":40},"2025-07-04",{"date":275,"type":40},"2025-06-30",{"date":277,"type":21},"2027-12-30",{"name":279,"class":47},"Hospices Civils de Lyon",{"id":281,"slug":282,"hasResults":11,"nctId":283,"briefTitle":284,"officialTitle":285,"acronym":4,"eligibilityCriteria":286,"healthyVolunteers":11,"sex":16,"minAge":287,"maxAge":4,"enrollmentInfo":288,"targetDuration":4,"studyType":290,"phases":4,"briefSummary":291,"conditions":292,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":294,"lastUpdatePostDateStruct":295,"startDateStruct":297,"completionDateStruct":299,"leadSponsor":301,"locationsCount":48},"100588352","food-intake-of-hospitalized-elderly-and-its-influence-on-muscular-and-clinical-outcomes-100588352","NCT06940284","Food Intake of Hospitalized Elderly and Its Influence on Muscular and Clinical Outcomes","Food Intake of Hospitalized Elderly and Its Influence on Muscular and Clinical Outcomes: A Prospective Cohort Study","Inclusion Criteria:\n\n* both sex;\n* 65 years and older;\n* hospital stay less than 48 hours;\n\nExclusion Criteria:\n\n* cancer in the last 5 years;\n* delirium;\n* cognitive deficit that impossibility the patient to read and sign the informed consent form;\n* neurological disease;\n* neurodegenerative muscular disease;\n* patients receive nutrition via enteral and parenteral routes.","65 Years",{"count":289,"type":21},60,"OBSERVATIONAL","The objectives of the present study are: 1) to characterize the energy-protein intake of the elderly during hospitalization; 2) to verify the influence of energy-protein intake during hospitalization on muscular (i.e., cross-sectional area of the rectus femoris and vastus lateralis muscles, muscle strength, functionality and level of independence) and clinical (i.e., length of hospital stay, hospital readmission and mortality) at the time of hospital discharge, 2 and 6 months after hospital discharge and; 3) to verify whether energy-protein intake during hospitalization is a significant predictor of loss of function and muscle mass, length of hospital stay, hospital readmission rate and mortality.",[293,28],"Atrophy, Muscular","2025-05-22",{"date":296,"type":40},"2025-05-23",{"date":298,"type":40},"2025-05-01",{"date":300,"type":21},"2026-01-30",{"name":302,"class":47},"University of Sao Paulo General Hospital",{"id":304,"slug":305,"hasResults":11,"nctId":306,"briefTitle":307,"officialTitle":308,"acronym":4,"eligibilityCriteria":309,"healthyVolunteers":11,"sex":16,"minAge":234,"maxAge":4,"enrollmentInfo":310,"targetDuration":4,"studyType":22,"phases":312,"briefSummary":314,"conditions":315,"keywords":316,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":318,"lastUpdatePostDateStruct":319,"startDateStruct":321,"completionDateStruct":323,"leadSponsor":325,"locationsCount":48},"100468433","phase-2-nutritional-supplementation-in-head-and-neck-cancers-100468433","NCT05379712","Nutritional Supplementation in Head and Neck Cancers","A Randomized Open Label Trial of Multimodal Oral Nutritional Supplementation Versus Standard Care, to Prevent \u002F Attenuate Malnutrition in Patients with Cancers of the Head and Neck Receiving (chemo)-radiotherapy Treatment.","Inclusion Criteria:\n\n1. Patients must have the ability to read, understand, and sign an informed consent and must be willing to comply with study treatment and follow-up.\n2. Male or female\n3. ≥18 years of age\n4. Histopathologically confirmed primary squamous cell carcinoma of the oral cavity and oropharynx, larynx or hypopharynx, who have agreed to receive radical intent radiotherapy as primary treatment or adjuvant treatment post-surgery, with or without platinum chemotherapy\n5. Capable of volitional oral nutritional intake at baseline.\n6. A diagnostic CT image taken with a maximum of 30 days before initiation of radical intent radiotherapy. If the CT scan history in the patient's clinical record does not include a study within this window, a baseline non-contrast enhanced CT abdomen will be conducted.\n7. An Eastern Cooperative Oncology Group Performance Status of ≤ 2\n\nExclusion Criteria:\n\n1. Fed by nasogastric tube, gastrostomy or total parenteral nutrition\n2. Cancer of the nasopharynx, thyroid or salivary gland\n3. Life expectancy \\\u003C6 months.\n4. A known hypersensitivity \u002F allergy to the investigational product or to any ingredient in their formulations (e.g. Milk\u002FLactose, Fish).\n5. Enrolment in any other clinical protocol or investigational study with an interventional agent or assessments that may interfere with study procedures.\n6. Patients with untreated brain metastases (patients with previously resected and\u002For radiated brain metastases without neurologic symptoms are permitted).\n7. Poorly controlled chronic illnesses or other inflammatory diseases (e.g. COPD, uncontrolled non-insulin dependent diabetes, rheumatoid arthritis).\n8. In the investigators' opinion, patients who have medical conditions that could interfere with nutrient metabolism or absorption (e.g., short bowel syndrome, Crohn's disease, etc.)",{"count":311,"type":21},81,[313],"PHASE2","The purpose of this study is to determine whether multimodal nutrition therapy (primary nutrition intervention + adjuvant nutrition therapy) will support patients to optimize their total caloric intake during cancer treatment by measuring the difference in mean cumulative energy intake between the intervention and control group over the duration of cancer treatment.",[184,185,28],[317,187],"Nutritional Support","2025-03-25",{"date":320,"type":40},"2025-03-28",{"date":322,"type":40},"2024-10-25",{"date":324,"type":21},"2026-10",{"name":326,"class":47},"AHS Cancer Control Alberta",{"id":328,"slug":329,"hasResults":11,"nctId":330,"briefTitle":331,"officialTitle":331,"acronym":4,"eligibilityCriteria":332,"healthyVolunteers":56,"sex":16,"minAge":333,"maxAge":334,"enrollmentInfo":335,"targetDuration":4,"studyType":22,"phases":337,"briefSummary":338,"conditions":339,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":344,"startDateStruct":346,"completionDateStruct":348,"leadSponsor":350,"locationsCount":48},"100463187","nutri-cap-nutrition-for-children-adolescent-girls-and-pregnant-women-in-slums-of-dhaka-city-100463187","NCT05311436","Nutri-CAP: Nutrition for Children, Adolescent Girls, and Pregnant Women in Slums of Dhaka City","Inclusion Criteria:\n\n* Pregnant women:\n\n  * Age 18-39 years\n  * Before 16 weeks of gestation\n  * BMI 15-24.99 kg\u002Fm2 measured on enrolment\n  * Have the plan to stay in the study area till delivery\n  * Willing to participate in the study\n  * Not enrolled in any nutrition project\u002Fprogramme currently\n\nAdolescent girls:\n\n* Aged 11-19 years\n* Willing to participate in the study\n* Not involved in any nutrition project\u002Fprogramme\n* Will stay in the study area for the next 2 years\n\nChildren:\n\n* Aged 0-24 months\n* Youngest child of the household\n* Caregivers have the plan to stay in the study area at least up to two years of age\n* Not enrolled in any nutrition project\u002Fprogramme currently\n\nExclusion Criteria:\n\n* Pregnant women:\n\n  * Subject not willing to provide consent\n  * Subject has the plan to migrate outside of the study area during the study period\n  * Subject has a plan to go elsewhere ( village\u002F parents' house) for delivery\n  * Any reported\u002Fdiagnosed chronic diseases (such as hypertension, heart disease, chronic obstructive pulmonary disease, chronic kidney disease, chronic liver disease, pancreatic diseases, diabetes mellitus, thyroid dysfunction, immunological diseases, malignancy, or any other diseases which could impede compliance with the study protocol)\n  * Extremely obese\n  * Subject involved in any nutrition programme\u002F intervention currently\n\nAdolescent girls:\n\n* Subject not willing to give assent\u002Fconsent\n* Subject has the plan to migrate outside the study area during the study period\n* Subject involved in any nutrition programme\u002Fintervention currently\n\nChildren:\n\n* Caregiver\u002Fguardian not willing to provide consent\n* Have the plan to migrate outside of the study area during the study period\n* Child with any congenital anomaly\n* Subject involved in any nutrition programme\u002Fintervention currently","1 Day","39 Years",{"count":336,"type":21},3278,[24],"The objective of the research project is to establish an evidence-based sustainable nutrition service delivery platform for optimizing pregnancy weight gain, increasing dietary diversity of adolescent girls, and ensuring proper physical growth of under 2 children.\n\nHypothesis\n\n1. Pregnant Women: Intensive nutrition and WASH counseling, iron-folate, calcium supplementation during pregnancy, can improve gestational weight gain and improve hemoglobin status in pregnant women in a slum of Dhaka city\n2. Adolescent girl: Iron and zinc supplementation and nutrition counseling on dietary diversity could improve nutritional status and dietary diversity score in adolescent girls of slums in Dhaka\n3. Children \\\u003C2 years: Counselling on IYCF, growth monitoring, and promotion, ensuring six-monthly vitamin A supplementation, counseling on WASH, treatment of acute malnutrition, and daily 1 egg supplementation for 3 months for severely stunted children can improve the nutritional status of children\n4. Counselling to improve Water, Sanitation and Hygiene (WASH) practice: WASH intervention can improve EED biomarkers",[340,341,28,342],"Gestational Weight Gain","Diet, Food, and Nutrition","Health Behavior","2024-10-27",{"date":345,"type":40},"2024-10-30",{"date":347,"type":40},"2022-04-01",{"date":349,"type":21},"2024-12-31",{"name":351,"class":47},"International Centre for Diarrhoeal Disease Research, Bangladesh",{"id":353,"slug":354,"hasResults":11,"nctId":355,"briefTitle":356,"officialTitle":357,"acronym":358,"eligibilityCriteria":359,"healthyVolunteers":11,"sex":16,"minAge":360,"maxAge":147,"enrollmentInfo":361,"targetDuration":4,"studyType":22,"phases":363,"briefSummary":364,"conditions":365,"keywords":369,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":374,"lastUpdatePostDateStruct":375,"startDateStruct":377,"completionDateStruct":379,"leadSponsor":381,"locationsCount":81},"100500057","double-duty-interventions-and-its-impact-on-double-burden-of-malnutrition-in-children-under-five-years-100500057","NCT05791305","Double Duty Interventions and Its Impact on Double Burden of Malnutrition in Children Under Five Years","Double Duty Interventions and Its Impact on DBM Among Children Under Five Years Ethiopia: A Cluster Randomized Controlled Trial","DBM","Inclusion Criteria:\n\n* who attend the intervention\n\nExclusion Criteria:\n\n* who are not attended the intervention","2 Years",{"count":362,"type":21},456,[24],"Background: Double burden of malnutrition is an emerging public health problem among children under-five years due to the inevitable consequences of nutritional transition. Addressing these two contrasting forms of malnutrition (undernutrition and overnutrition) simultaneously brings an enormous challenge to the food and nutrition policies of developing countries like Ethiopia. Children under five ages are more vulnerable to DBM, especially during the first year of their life due to high growth and inadequate diet. Hence, there has been a paradigm shift in thinking to reduce its effect on the health of children. However, interventions that are used to address these different kinds of malnutrition are implemented through different governance and still, they are isolated and disintegrated each other. Therefore, double-duty interventions can tackle the risk of both nutritional problems simultaneously in an integrated approach through nutrition behavior change communication.\n\nObjective: Therefore, the main aim of this pilot study is to assess the effect of selected double-duty interventions on the double burden of malnutrition among children under five years in Debre Berhan City, Ethiopia.",[366,183,367,28,368],"Malnutrition","Obesity","Thinness",[370,371,372,28,373],"Double burden of malnutrition","Double-duty interventions","Children under five years","Overnutrition","2024-08-07",{"date":376,"type":40},"2024-08-09",{"date":378,"type":40},"2023-04-10",{"date":380,"type":21},"2025-12-30",{"name":382,"class":47},"Debre Berhan University"]