[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"unhealthy-alcohol-use\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:unhealthy-alcohol-use":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,45,73,116],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100586648","screening-and-brief-intervention-of-post-war-alcohol-consumption-in-public-hospital-outpatients-100586648",false,"NCT06918106","Screening and Brief-Intervention of Post-war Alcohol Consumption in Public Hospital Outpatients","Inclusion Criteria:\n\n* All gender (Female \\& Male patients)\n* Outpatients aged 18 years and above\n* Outpatients with no serious medical or mental illnesses\n* Outpatients who will be identified to have AUDIT score of 8-19\n\nExclusion Criteria:\n\n* Age less than 18 years\n* Outpatients with serious medical or mental illnesses\n* Outpatients with AUDIT score of less than 7 and above 20","ALL","18 Years",{"count":18,"type":19},262,"ESTIMATED","INTERVENTIONAL",[22],"NA","Background:\n\nHigh prevalence of alcohol-consumption among conflict-affected population has been reported in some low-and-middle income countries. However, studies that assess the effectiveness of screening and brief-intervention (SBI) in the reduction of unhealthy alcohol consumptions among conflict-affected hospital outpatients in Tigray are insufficient.\n\nObjective:\n\nThis study aims to test the effectiveness of Screening and Brief-Intervention (SBI) in the reduction of unhealthy alcohol consumptions among conflict-affected hospital outpatients in Tigray.\n\nMethod:\n\nAbout 1260 outpatients will be screened for alcohol consumption using Alcohol Use Disorder Identification Test (AUDIT). Those who will have \"8-19\" scores in the AUDIT will be allocated to \"Intervention\" and \"Control\" groups using block randomization and they will be followed at 6 and 12 months of follow - up. The Intervention group will receive simple advice, brief-counseling and 6-and 12-months follow-up screening of alcohol consumptions. However, outpatients in control group will only receive 6- and 12-months follow-up screening of alcohol consumptions. Data will be entered to and will be analyzed using SPSS V 26. Means, standard deviations and percentages will be used for descriptive statistics. Bivariate and multivariate logistic regression, at 95% of confidence interval and p-value of \\\u003C0.05, will be used to identify correlates of alcohol consumption. Independent sample t-test and Mann-Whitney U test will be used to compare AUDIT mean scores of normally and none-normally distributed continuous variables between intervention and control groups respectively.",[25,26],"Effectiveness of Screening and Brief-Intervention","Unhealthy Alcohol Use",[28,29,30,31],"Post-war alcohol use","Screening and Brief-intervention","Harmful alcohol use","Hazardous alcohol use","RECRUITING","2026-06-05",{"date":35,"type":36},"2026-06-08","ACTUAL",{"date":38,"type":36},"2025-04-03",{"date":40,"type":19},"2026-07-10",{"name":42,"class":43},"Aksum University","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":20,"phases":54,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":44},"100477915","telehealth-for-pain-and-unhealthy-drinking-among-plwh-100477915","NCT05503173","Telehealth for Pain and Unhealthy Drinking Among PLWH","Integrated Telehealth Intervention To Reduce Chronic Pain And Unhealthy Drinking Among People Living With HIV (PLWH)","Inclusion Criteria:\n\n* Able to confirm HIV diagnosis, via visual evidence of antiretroviral (ART) medication bottle or medical record presented to study staff over Zoom.\n* Engaged in unhealthy drinking, defined as:\n* \\>7 drinks for women \u002F \\> 14 drinks for men per week.\n* OR ≥ 3 drinks for women \u002F ≥4 drinks for men on one occasion in the past month.\n* Experiencing moderate or greater chronic pain (4 or greater on the numerical pain rating scale) for at least 3 months.\n* Own a smart phone.\n* Lives in the USA.\n* Has a US mailing address.\n\nExclusion Criteria:\n\n* History of bipolar, schizoaffective disorder or schizophrenia per self report.\n* Unstable dose of psychoactive medication for pain or alcohol\u002Fsubstance use \\[i.e., if on medication, participant has not been on same dose for least 2 months\\]\n* History of withdrawal-related seizures or delirium tremens\n* Current non-pharmacological treatment for alcohol use disorder or chronic pain\n* Acute life-threatening illness that requires treatment or intend to have surgery for a pain-related condition in the next 6-months.\n* Current cancer-related pain\n* Unable to provide one or more individuals for follow-up contact\n* Individual who is unwilling to provide their sex at birth\n* Limited or non-readers",{"count":53,"type":19},385,[22],"This randomized controlled trial is a between-groups design to compare the Motivational and Cognitive Behavioral Management for Alcohol and Pain (MCBMAP) Intervention to a Brief Advice and Information Control condition.\n\nTwo-hundred and fifty participants who have HIV with moderate or greater chronic pain will be randomized for the trial. Recruitment will take place through digital media. A unique feature of this intervention trial is that most of the procedures will be conducted remotely which will minimize barriers of transportation and time for participants. Consent and baseline assessment will be completed remotely. Following baseline assessment, participants will complete two weeks of ecological momentary assessment (EMA) to assess alcohol use, chronic pain, physical function and mechanisms of behavior change for alcohol and pain management. Following the two-week phase, participants will be randomly assigned to either the intervention or control condition and meet the interventionist through videoconferencing. Participants will complete outcome assessment measures at 3- and 6-months post-baseline. Following the 3-month outcome assessment, participants will complete another two weeks of EMA.",[57,58,26],"HIV","Chronic Pain",[60,61,62,63],"Pain management","Telehealth","Unhealthy drinking","Ecological momentary assessment","2026-05-26",{"date":66,"type":36},"2026-05-28",{"date":68,"type":36},"2023-03-03",{"date":70,"type":19},"2026-12",{"name":72,"class":43},"Boston University",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":15,"minAge":82,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":20,"phases":85,"briefSummary":86,"conditions":87,"keywords":98,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":44},"100617156","impact-of-lifestyle-on-health-maintenance-a-randomized-controlled-trial-100617156","NCT07314957","Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial","The Role of Lifestyle in Maintaining Health: Biological, Psychological and Social Responses of the Organism to Lifestyle","LifeHealth-RCT","Inclusion Criteria:\n\n* adults aged 20 years and older\n* overweight or obesity (BMI ≥25 kg\u002Fm²),\n* stable body weight over the past 6 months\n* physically inactive.\n\nExclusion Criteria:\n\n* HbA1c \\>12%\n* insulin therapy\n* severe psychiatry and severe chronic illnesses of parents\n* diseases of the hypothalamus and pituitary and adrenal gland\n* mobility restriction\n* tetraplegia\n* use of obesity pharmacotherapy\n* malignant disease and chemotherapy\n* pregnancy",true,"20 Years",{"count":84,"type":19},120,[22],"This study aims to evaluate the impact of public health interventions on changes in healthy lifestyle habits over time and their subsequent effects on health outcomes. The investigators hypothesize that exposing at-risk populations to structured physical activity programs, education on healthy nutrition, promotion of the Mediterranean diet, and workshops focused on strengthening psychological resilience will lead to improvements in anthropometric, oxidative, metabolic, and psychological parameters. Anthropometric and laboratory measures will be collected at multiple time points throughout the study. The longitudinal follow-up will span 12 months. It is anticipated that sustained adherence to healthy lifestyle behaviors will result in positive lifestyle changes and enhanced health-related quality of life.",[88,89,90,26,91,92,93,94,95,96,97],"Metabolic Syndrome","Inactivity\u002FLow Levels of Exercise","Unhealthy Diet","Smoking Behaviors","Stress","Sleep Disorder","Obesity & Overweight","Anxiety","Depressed Mood","Emotional Eating Behaviour",[99,100,101,102,92,103,104,105],"Habits","Lifestlye","Nutrition","Phisical activity","Metabolic syndrome","Mental health","Sleep","NOT_YET_RECRUITING","2026-02-09",{"date":109,"type":36},"2026-02-12",{"date":111,"type":19},"2026-09-01",{"date":113,"type":19},"2027-12-31",{"name":115,"class":43},"University of Zadar",{"id":117,"slug":118,"hasResults":11,"nctId":119,"briefTitle":120,"officialTitle":120,"acronym":4,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":122,"targetDuration":4,"studyType":20,"phases":124,"briefSummary":125,"conditions":126,"keywords":128,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":44},"100540529","systematic-implementation-of-patient-centered-care-for-alcohol-use-trial-beyond-referral-to-treatment-100540529","NCT06318026","Systematic Implementation of Patient-centered Care for Alcohol Use Trial: Beyond Referral to Treatment","Inclusion Criteria:\n\n1. Adult primary care patients ≥18 years old on the day of a primary care appointment; and\n2. ≥4 symptoms on the Alcohol Symptom Checklist, or 2-3 symptoms on the Alcohol Symptom Checklist with at least one symptom associated with high risk of progression to severe symptoms, documented in the electronic health record associated with the primary care appointment; and\n3. high-risk drinking on the alcohol screening questionnaire (AUDIT-C ≥7) on the day of the Alcohol Symptom Checklist or in the prior 30 days documented in the electronic health record.\n\nExclusion Criteria:\n\n1. Documented request to not participate in research, or\n2. Patient was eligible for the Vanguard pilot study.",{"count":123,"type":19},1500,[22],"The Systematic Implementation of Patient-centered Care for Alcohol Use Trial is a pragmatic, cluster-randomized, effectiveness-implementation trial testing two interventions in Kaiser Permanente Washington to systematically implement shared decision-making with primary care patients with symptoms due to alcohol use: a primary care intervention and a centralized intervention. An anticipated 25 primary care clinics will be randomized to one of three conditions: usual care or the primary care or centralized interventions.",[127,26],"Alcohol Use Disorder",[129,130,131,132,133],"Patient-centered care","Shared decision-making","Population-based management","Quality improvement","Decision aid","2025-05-05",{"date":136,"type":36},"2025-05-06",{"date":138,"type":36},"2025-03-25",{"date":140,"type":19},"2029-02",{"name":142,"class":43},"Kaiser Permanente"]