[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"upper-extremity-paralysis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:upper-extremity-paralysis":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,54],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":33,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100488290","nerve-transfer-surgery-to-restore-upper-limb-function-after-cervical-spinal-cord-injury-100488290",false,"NCT05638191","Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury","Inclusion Criteria:\n\n* Traumatic, motor-complete cervical SCI (AIS A or B)\n* Male or female, ages 18-70\n* Consent and plan to undergo nerve transfer to restore grasp function in at least one limb\n* Motor grade 4-5 at C5\n* Motor grade 0-1 at C8\u002FT1\n* Injury duration within 6 months at the time of surgery\n* English-speaking and cognitively intact\n* Able to provide informed written consent\n* Able to attend and comply with the testing protocols\n\nExclusion Criteria:\n\n* Inability or unwillingness to participate in post-operative rehabilitation (in person or virtual)\n* Secondary complication of SCI (e.g., intractable neuropathic pain, edema, contracture) or major medical comorbidity (e.g., traumatic brain injury) that would independently influence response to surgery or ability to participate in rehabilitation","ALL","18 Years","70 Years",{"count":19,"type":20},40,"ESTIMATED","2 Years","OBSERVATIONAL","The goal of this prospective, open-label cohort study is to assess functional outcomes in individuals with cervical spinal cord injury who have undergone nerve transfer surgery to restore upper limb function. The main questions it aims to answer are:\n\n* Does nerve transfer improve hand function in individuals with cervical spinal cord injury?\n* What factors are associated with functional improvement following nerve transfer? Researchers will compare functional outcomes at 24 months post-surgery to 1) baseline outcomes and 2) individuals with cervical spinal cord injury who did not undergo nerve transfer.\n\nParticipants who have received nerve transfer surgery as part of their regular medical care will complete functional hand tests, electrodiagnostic assessments, and questionnaires on independence and mood every 3 months for 24 months after surgery.",[25,26,27,28,29,30,31,32],"Spinal Cord Injury","Spinal Cord Injury at C5-C7 Level","SCI - Spinal Cord Injury","Upper Extremity Paralysis","Upper Extremity Dysfunction","Tetraplegia","Upper Extremity Paresis","Cervical Spinal Cord Injury",[34,35,36,37,38,39,40],"spinal cord injury","upper extremity nerve transfer","nerve transfer","SCI","nerve reconstruction","quadriplegia","paresis","RECRUITING","2026-05-27",{"date":44,"type":45},"2026-05-29","ACTUAL",{"date":47,"type":45},"2021-06-03",{"date":49,"type":20},"2028-01",{"name":51,"class":52},"University of British Columbia","OTHER",4,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":15,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":84},"100527789","virtual-reality-based-mirror-therapy-100527789","NCT06152328","Virtual Reality Based Mirror Therapy","A New Perspective on Mirror Therapy: The Effect of Leap Motion-Based Multi-Axis Immersive Virtual Reality Mirror Therapy (LISA) on Upper Extremity Functions in Individuals With Stroke","Inclusion Criteria:\n\n* Have a ischemic stroke\n* Stroke duration not less than 2 months and not more than 6 months\n* Individuals with a score of 2b and 3 according to the Thrombolysis in cerebral infarction (TICI) scale\n* A score of 2 and above according to the upper extremity motor assessment of the NIH stroke scale\n* Intact depth perception in the Titmus Stereopsis assessment\n* A score of 24 and above in the Mini-mental test and\n* Independent sitting balance\n\nExclusion Criteria:\n\n* Additional neurologic diseases\n* Have a head injury\n* Have a brain tumor\n* Prior cranial surgery\n* Psychological disorder or mental problem\n* Previous stroke\n* Aphasia and apraxia\n* Upper extremity amputation","40 Years","80 Years",{"count":64,"type":20},56,"INTERVENTIONAL",[67],"NA","The aim of this study is to examine the effectiveness of 3D virtual reality assisted mirror therapy based rehabilitation applications compared to classical methods used in stroke rehabilitation.",[70,31,28],"Stroke",[72,73,74],"Rehabilitation","Virtual Reality Immersion Therapy","Mirror Movement Therapy","2026-05-02",{"date":77,"type":45},"2026-05-07",{"date":79,"type":45},"2024-04-01",{"date":81,"type":20},"2026-06-15",{"name":83,"class":52},"Abant Izzet Baysal University",1]