[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"upper-extremity-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:upper-extremity-surgery":78},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100643126","comparison-of-90-and-120-arm-positions-in-costoclavicular-block-100643126",false,"NCT07586670","Comparison of 90° and 120° Arm Positions in Costoclavicular Block","Effect of Arm Abduction Degree ( 90° vs. 120° ) on Block Onset Time and Block Success in Costoclavicular Brachial Plexus Block in Patients Undergoing Hand, Wrist and Forearm Surgery: A Prospective Randomized Controlled Trial","COSTO-RCT","Inclusion Criteria:\n\n* Patients aged between 18 and 80 years.\n* Patients scheduled for elective upper extremity surgery (hand, wrist, forearm).\n* Patients classified as ASA I-III.\n* Patients who provide informed consent after being informed about the study.\n\nExclusion Criteria:\n\n* History of previous surgery, scar tissue, tumor, or trauma that may alter brachial plexus anatomy.\n* Presence of infection, hematoma, severe edema, burn, or open wound at the block application site.\n* Known allergy to local anesthetics or other medications used in the study.\n* Coagulopathy, use of anticoagulants, or platelet count \\\u003C 100,000\u002Fmm³.\n* History of peripheral neuropathy, neurological deficit, cervical radiculopathy, or CRPS.\n* Pregnancy or breastfeeding.\n* Patients with BMI \\\u003C 18 kg\u002Fm².\n* Patients with BMI \\> 35 kg\u002Fm².\n* Severe cardiac, pulmonary, renal, or hepatic failure.\n* Mental retardation, communication difficulties, or lack of cooperation.\n* Deformity, amputation, or large mass in the surgical extremity that may interfere with sensorimotor assessment.\n* Preoperative significant sensory loss, motor weakness, or signs of neurological disease.\n* Severe anemia (Hb \\\u003C 9 g\u002FdL) or polycythemia (Hb \\> 18 g\u002FdL).\n* Psychiatric disorders, substance abuse, or any condition that may interfere with study compliance.","ALL","18 Years","80 Years",{"count":21,"type":22},106,"ESTIMATED","INTERVENTIONAL",[25],"NA","The costoclavicular approach of the infraclavicular brachial plexus block is widely used for upper extremity surgeries due to its reliable anatomy and high success rates. Patient positioning, particularly the degree of arm abduction, may influence the spread of local anesthetic and the characteristics of the block. However, the optimal arm abduction angle during this procedure remains unclear.\n\nThis prospective randomized controlled trial aims to investigate the effect of two different arm abduction angles (90° and 120°) on block onset time and block success in patients undergoing hand, wrist, and forearm surgery under ultrasound-guided costoclavicular brachial plexus block.\n\nPatients will be randomly assigned to one of two groups according to the degree of arm abduction. The primary outcome is block onset time. Secondary outcomes include block success, sensory and motor block characteristics, perfusion index changes, hemodynamic parameters, readiness for surgery at 15 and 20 minutes, block performance time, need for additional anesthesia, postoperative neurological evaluation at 4 and 24 hours, complications, and patient satisfaction.\n\nThe findings of this study are expected to provide evidence on optimal patient positioning to improve the effectiveness and reliability of ultrasound-guided costoclavicular brachial plexus block.",[28,29,30,31],"Perfusion Index","Upper Extremity Surgery","Brachial Plexus Block","Regional Anaesthesia","NOT_YET_RECRUITING","2026-06-06",{"date":35,"type":36},"2026-06-09","ACTUAL",{"date":38,"type":22},"2026-05-15",{"date":40,"type":22},"2026-08-27",{"name":42,"class":43},"Ankara Etlik City Hospital","OTHER_GOV",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":53,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":77},"100612149","phase-2-a-randomized-comparison-between-067-mcgkg-1-mcgkg-and-133-mcgkg-of-perineural-dexmedetomidine-for-ultrasound-guided-infraclavicular-block-100612149","NCT07249827","A Randomized Comparison Between 0.67 mcg\u002Fkg, 1 mcg\u002Fkg, and 1.33 mcg\u002Fkg of Perineural Dexmedetomidine for Ultrasound-Guided Infraclavicular Block","Inclusion Criteria:\n\n* patients undergoing upper limb surgery at or below the elbow\n* age between 18 and 75 years\n* American Society of Anesthesiologists classification 1-3\n* body mass index between 18 and 35 kg\u002Fm2\n\nExclusion Criteria:\n\n* adults who are unable to give their own consent\n* allergy or contraindication to dexmedetomidine\n* exposure to dexmedetomidine during the previous 48 hrs\n* pre-existing neuropathy (assessed by history and physical examination)\n* coagulopathy (assessed by history and physical examination and, if deemed clinically necessary, by blood workup i.e. platelets ≤ 100, International Normalized Ratio ≥ 1.4 or partial prothrombin time ≥ 50)\n* renal failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work-up i.e. creatinine. eGFR \\\u003C 90)\n* hepatic failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work-up i.e. transaminases ≥ 100)\n* allergy to LA\n* pregnancy (as institutional policy, female patients with childbearing potential undergoing non urgent surgery are tested preoperatively for pregnancy with blood tests)\n* breast feeding\n* prior surgery in the infraclavicular region\n* chronic pain syndromes requiring opioid intake at home","75 Years",{"count":52,"type":22},69,[54],"PHASE2","This study will compare three different doses of perineural dexmedetomidine 0.67 mcg\u002Fkg, 1 mcg\u002Fkg, and 1.33 mcg\u002Fkg as adjuvants to local anesthetics for ultrasound-guided infraclavicular brachial plexus blocks (ICBs). Our research hypothesis is that 1.33 mcg\u002Fkg will provide a 15%-longer duration than 1mcg\u002Fkg, which in turn will provide a 15%-longer duration than 0.67 mcg\u002Fkg. Since analgesic duration and sensory duration can be influenced by intake of pain medications and surgical trauma to small cutaneous nerves, respectively, we will select motor block duration as the main outcome to better target the action of dexmedetomidine on the brachial plexus.",[57,58,29,59],"Analgesia","Pain, Acute","Nerve Block",[57,61,62,63,64,65],"Acute pain","Brachial plexus","Brachial plexus block","Postoperative pain","Nerve block","RECRUITING","2026-01-04",{"date":69,"type":36},"2026-01-07",{"date":71,"type":36},"2025-12-28",{"date":73,"type":22},"2026-06-30",{"name":75,"class":76},"McGill University Health Centre\u002FResearch Institute of the McGill University Health Centre","OTHER",1,"Upper-extremity Surgery"]