[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"upper-gastrointestinal-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:upper-gastrointestinal-disorder":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100449464","high-resolution-manometry-after-partial-fundoplication-for-gastro-oesophageal-reflux-100449464",false,"NCT05132816","High Resolution Manometry After Partial Fundoplication for Gastro-oesophageal Reflux","High Resolution Manometry After Partial Fundoplication for Gastro-oesophageal Reflux: Does the Ineffective Preoperative Oesophageal Motility Change Postoperatively?","Inclusion Criteria:\n\n* Age older than 18 years\n* Ineffective esophageal motility disorder according the Chicago classification (7), defined as ≥ 7\u002F10 (70%) of swallows with weak contraction (distal contraction interval (DCI) between 100mmHg\u002Fs\u002Fcm and less than 450 mmHg\u002Fs\u002Fcm) or ≥ 5\u002F10 (50%) of swallows with failed peristalsis (DCI \\\u003C100mgHg\u002Fs\u002Fcm)Performance of partial fundoplication (180° anterior or 270° posterior) at Spital Limmattal\n* Informed Consent as documented by signature\n\nExclusion Criteria:\n\n* Age under 18 years\n* Pregnancy\n* Normal preoperative esophageal motility\n* Other specifically defined esophageal motility disorders such as Nutcracker or Jackhammer esophagus\n* Preoperative presence of a hiatal hernia with migration of \\>20% of stomach in the chest\n* Revisional surgery (after other procedures for reflux or at the hiatus)","ALL","18 Years",{"count":19,"type":20},100,"ESTIMATED","INTERVENTIONAL",[23],"NA","This is a combined retro- and prospective, monocentric study. All patients who underwent or are planned for laparoscopic partial fundoplication (180° anterior or 270° posterior) between 2020-2023 are assessed for preoperative ineffective esophageal motility (IEM).\n\nThe main hypothesis is, that preoperative oesophageal motility disorders, especially hypo-contractility or failed peristalsis, are caused by gastro-oesophageal reflux. Therefore, postoperative manometry after partial wrap fundoplication (270° posterior, 180° anterior) shows a decrease in comparison to preoperative motility disorders.\n\nThe primary objective of this study is to examine the postoperative esophageal motility in patients with known preoperative motility disorders.\n\nSecondary endpoints are the presence of other oesophageal motility disorders pre- vs. postoperatively (including new onset disorders), the assessment of the Gastrointestinal Symptom Rating Scale (GSRS) pre- vs. postoperatively, and more.\n\nIf IEM is present preoperatively, patients are contacted at least 1 year after surgery and will be informed about the study and asked to participate. In case of agreement, they are invited to the study site. They undergo high-resolution manometry 18-24 months postoperatively (study intervention).",[26,27,28],"Gastroesophageal Reflux","Esophageal Motility Disorders","Upper Gastrointestinal Disorder","RECRUITING","2026-06-08",{"date":32,"type":33},"2026-06-09","ACTUAL",{"date":35,"type":33},"2022-01-24",{"date":37,"type":20},"2027-12-31",{"name":39,"class":40},"Prof Urs Zingg","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":51,"briefSummary":52,"conditions":53,"keywords":54,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":41},"100560735","performance-characteristics-and-technical-outcomes-of-single-use-vs-reusable-gastroscopes-evaluated-in-the-or-100560735","NCT06581016","Performance Characteristics and Technical Outcomes of Single-use vs. Reusable Gastroscopes Evaluated in the OR","Performance Characteristics and Technical Outcomes of Single-use Versus Reusable Gastroscopes Evaluated in the Operating Room in Acute, Subacute and Elective Patients","Inclusion Criteria:\n\n* Acute, subacute or elective gastroscopies in the operating theater\n* Age ≥ 18 years\n\nExclusion Criteria:\n\n* None",{"count":50,"type":20},700,[23],"The goal of this clinical trial is to investigate whether single-use gastroscopes are as good as reusable gastroscopes when used in the operation theater in all patients where gastroscopy in the operation theater is indicated. The main question it aims to answer is:\n\n\\- Is the technical success and performance characteristics the same for single-use and reusable gastroscopies?\n\nResearchers will compare single-use gastroscopes with reusable gastroscopes to see if the technical success and performance characteristics are the same in the to groups.\n\nParticipants will in the first period have gastroscopy with a single-use gastroscope. In the second period participants will have gastroscopy with a reusable gastroscope.",[28],[55,56,57,58,59],"Gastroscopy","Upper endoscopy","Gastroscope","Single-use","Reusable","2026-01-07",{"date":62,"type":33},"2026-01-09",{"date":64,"type":33},"2024-09-01",{"date":66,"type":20},"2026-09-30",{"name":68,"class":40},"Zealand University Hospital",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":21,"phases":77,"briefSummary":78,"conditions":79,"keywords":80,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":41},"100575347","performance-characteristics-and-technical-outcomes-of-single-use-gastroscopes-used-bedside-versus-reusable-gastroscopes-used-in-the-endoscopy-unit-evaluated-in-subacute-patients-100575347","NCT06771102","Performance Characteristics and Technical Outcomes of Single-use Gastroscopes Used Bedside Versus Reusable Gastroscopes Used in the Endoscopy Unit Evaluated in Subacute Patients","Inclusion Criteria:\n\n* Patients of any gender, 18 years of age or older admitted to the acute section of the surgical department (Kir2) at Zealand University Hospital referred to early EGD without general anesthesia.\n\nExclusion Criteria:\n\n* ASA-score of 4 or higher\n* Unstable patient\n* Suspicion of ventricular retention\n* Suspicion of active bleeders\n* Need for expert endoscopist to perform the procedure, e.g. stenting\n* Patients \\\u003C 18 years of age",{"count":76,"type":20},180,[23],"The aim of this study is to investigate whether single-use gastroscopes used bedside can reduce the time from indication to procedure compared with re-usable gastroscopes used at the endoscopy unit in patients referred to a subacute gastroscopy.\n\nParticipants in the first period will be scheduled for gastroscopy with a re-usable gastroscope in the endoscopy unit, whereas participants during the second period will have a gastroscopy performed at the ward (bed-side) with a single-use gastroscope.",[28],[55,56,57,58,59,81],"Bedside","2025-06-10",{"date":84,"type":33},"2025-06-15",{"date":86,"type":33},"2025-01-13",{"date":88,"type":20},"2027-04",{"name":68,"class":40}]