[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"upper-limb-amputation-below-elbow-injury\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:upper-limb-amputation-below-elbow-injury":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,79,111],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100617983","evaluation-of-the-phantom-x-implantable-emg-sensor-system-for-myoelectric-prosthesis-control-100617983",false,"NCT07325708","Evaluation of the Phantom X Implantable EMG Sensor System for Myoelectric Prosthesis Control","Clinical Evaluation of System for Bionic Arm Gesture Control (CYBORG)","CYBORG","Inclusion Criteria:\n\n1. Patient has a unilateral upper-limb difference (congenital or acquired) at the transradial or wrist level.\n2. The patient currently uses a myoelectric prosthesis or is deemed a suitable candidate for fitting with a myoelectric prosthesis.\n3. Patient is a suitable candidate for the implantation of the Phantom X sensor array as assessed by the implanting physician.\n4. Patient is at least 18 years old and can provide written informed consent.\n5. Patient is willing to comply with study protocol and make required study visits.\n6. Patient received amputation ≥ 12 months prior to consent.\n\nExclusion Criteria:\n\n1. Patient has a significant cognitive deficit resulting in inability to follow study directions.\n2. Patient has a neuro-muscular deficit and is unable to initiate substantial muscle contraction in the residual limb as determined by the implanting physician or investigator.\n3. Patient has another medical condition, which, in the opinion of the Investigator, may cause him\u002Fher to be non-compliant with the protocol, confound the data interpretation, or is associated with a life expectancy insufficient to allow for the completion of study procedures and follow-up.\n4. The patient has a planned medical procedure (e.g., surgery) during the study period that could interfere with compliance with study visits or assessments.\n5. Patient has an allergy to anesthesia or other medication used for sedation in the study.\n6. Patient has an active implantable device (e.g. cardiac pacemaker, neuromodulation device) that can potentially interfere with the performance of Phantom X system.\n7. Patient may require an MRI during the study duration.\n8. Implantation of the device poses a health risk to the patient as determined by the implanting physician.\n9. Women who are breastfeeding, currently pregnant or planning to become pregnant during the duration of the study or have a positive urine pregnancy test at screening.","ALL","18 Years",{"count":20,"type":21},10,"ESTIMATED","INTERVENTIONAL",[24],"NA","The CYBORG Study is a first-in-human clinical investigation evaluating the safety and performance of the Phantom X System, an implantable electromyography (EMG) sensor array designed to provide control of upper-limb prostheses. The study will assess surgical feasibility, device function, signal quality, and the system's ability to support intuitive prosthetic control during functional tasks. Participants will undergo implantation of the Phantom X sensors and complete a series of in-clinic visits to assess functional performance of the Phantom X system. Patient-reported outcomes will also be collected at various timepoints.",[27,28,29],"Upper Limb Amputation Below Elbow (Injury)","Wrist Disarticulation","Transradial Amputation",[31,32,33],"Upper limb amputation","Prosthesis","Myoelectric","RECRUITING","2026-06-21",{"date":37,"type":38},"2026-06-24","ACTUAL",{"date":40,"type":38},"2026-04-17",{"date":42,"type":21},"2027-06",{"name":44,"class":45},"Phantom Neuro Inc.","INDUSTRY",2,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":65,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":75,"locationsCount":78},"100514681","level-up-adaptive-gaming-for-children-with-upper-limb-differences-100514681","NCT05981664","Level Up! Adaptive Gaming for Children With Upper Limb Differences","Inclusion Criteria:\n\n* between the age of 7 and 17 years\n* has a unilateral limb difference\n* limb difference may be from any cause (congenital difference, traumatic loss, etc.)\n* limb difference may be of any level (partial hand, wrist disarticulation, transradial, elbow disarticulation, transhumeral, shoulder disarticulation)\n* ability to communicate in English\n* cognitive ability to follow instructions\n* eligible participants will be included regardless of history of prosthesis use\n* lives locally (Winnipeg) or willing and able to travel to Rehabilitation Centre for Children for 2 appointments\n\nExclusion Criteria:\n\n* less than 7 or greater than 17 years of age\n* bilateral or no limb upper limb difference\n* inability to communicate in English\n* cognitive inability to follow instructions\n* unable or unwilling to attend 2 appointments at Rehabilitation Centre for Children","7 Years","17 Years",{"count":56,"type":21},20,[24],"The goal of this clinical trial is to test a new one-handed video game controller adapter to determine if it helps improve how video games are played and enjoyed in children with an upper limb difference on one side. The main questions it aims to answer are:\n\n* Is performance improved while playing video games with the adapter?\n* Is user satisfaction or enjoyment improved while playing video games with the adapter?\n\nParticipants will:\n\n* Answer questions about their limb difference and other demographics\n* Be interviewed about their current and past video game playing experiences\n* Learn how to use the adapter and have their performance with it evaluated\n* Take the adapter home to use for 1 week, and be asked to record their experiences\n* Have their performance with the adapter re-evaluated after a week of practice\n* Be interviewed about their experience with the adapter",[60,61,62,63,64,27],"Upper Limb Amputation at the Wrist","Pediatric","Upper Limb Amputation","Upper Limb Amputation at the Hand","Amniotic Band Syndrome",[66,67,68],"pediatric","upper limb difference","one handed gaming","2026-04-28",{"date":71,"type":38},"2026-05-05",{"date":73,"type":38},"2024-01-01",{"date":42,"type":21},{"name":76,"class":77},"University of Manitoba","OTHER",1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":89,"conditions":90,"keywords":96,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":46},"100593821","effects-of-myoelectric-channel-count-and-targeting-for-upper-limb-prosthetic-control-100593821","NCT07011420","Effects of Myoelectric Channel Count and Targeting for Upper Limb Prosthetic Control","Evaluation of Functional Performance of Persons With Limb Differences to Optimize Pattern Recognition Control of Powered Upper Limb Prosthesis","Inclusion Criteria:\n\n* Unilateral transradial level limb absence\n* Current or past user of myo-electric controlled prostheses\n* Six months or more post-amputation\n* Have adequate limb length such that a wrist rotation device can fit in the check socket\n* Well-fitting socket as determined by a Socket-Comfort Score of 6 or above\n* Capable of wearing and operating a prosthesis with a wrist rotator and multi-articulating hand\n* Capable of understanding and following multi-step instructions and completing the tasks as described\n* English speaking\n\nExclusion Criteria:\n\n* Significant new injury that would prevent use of a prosthesis: The ability to consistently wear a prosthesis and perform activities of daily living and specific performance tasks is necessary to evaluate the relative benefits of the interventions.\n* Cognitive impairment sufficient to adversely affect understanding of or compliance with study requirements, ability to communicate experiences, or ability to give informed consent: The ability to understand and comply with requirements of the study is essential for the study to generate useable, reliable data. The ability to obtain relevant user feedback through questionnaires and informal discussion adds significant value to this study.",{"count":87,"type":21},32,[24],"The goal of this clinical trial is to systematically evaluate whether or not two commonly held fundamental assumptions for pattern recognition control translates to functional performance when tested on individuals aged 18 years or older with upper limb absence at the transradial level while wearing a physical prosthesis.\n\nThe specific aims of this study are:\n\n1. To evaluate the effect of changing untargeted myoelectric channel count on the functional performance of transradial prosthesis users wearing a fully functional prosthesis via functional outcomes measures such as the Box and Blocks test.\n2. To evaluate the effect of changing myoelectric channel targeting of a fixed number of myoelectric channels on the functional performance of transradial prosthesis users wearing a fully functional prosthesis via functional outcomes measures such as the Box and Blocks test.\n\nResearchers will perform a randomized crossover study to compare system configurations with different number of sensor channels and with various strategies for sensor placement on the limb. Participants will be assigned to a random test sequence that includes the following four different EMG channel conditions:\n\nCondition A: 4 untargeted channels Condition B: 8 untargeted channels Condition C: Up to 16 untargeted channels Condition D: 8 targeted channels\n\nResearchers will evaluate the effects of changing myoelectric channel counts on the functional prosthesis performance of individuals with transradial limb loss via functional outcome measures.\n\nParticipants will:\n\n* Attend up to 5 in-lab sessions that are expected to last 4 hours.\n* Conduct site visits every 1-2 weeks to complete functional and self reported outcome measures with each condition.\n* Play virtual games with the Coapt Cuff for 15 minutes a day, 3 days a week in between visits.",[91,92,93,94,27,95],"Amputation","Amputation, Traumatic","Amputation, Congenital","Prosthesis User","Amputation; Traumatic, Arm: Forearm, Between Elbow and Wrist",[97,98,99,100,101],"amputee","upper limb amputee","transradial amputee","prosthetic arm","upper limb prosthesis user","2025-09-02",{"date":104,"type":38},"2025-09-03",{"date":106,"type":21},"2025-10",{"date":108,"type":21},"2026-06",{"name":110,"class":45},"Liberating Technologies, Inc.",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":118,"targetDuration":4,"studyType":120,"phases":4,"briefSummary":121,"conditions":122,"keywords":124,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":78},"100428144","evaluating-the-experience-of-upper-limb-prosthesis-use-100428144","NCT04855214","Evaluating the Experience of Upper Limb Prosthesis Use","Patient-specific Requirements and Experiences of Upper Limb Prosthetic Technology","Inclusion Criteria:\n\n* 18 years or older\n* Ability to give verbal informed consent\n* Ability to speak and understand English\n* Unilateral acquired trans-radial or trans-humeral amputee\n* At least six months from time of limb loss\n* Current user of an upper limb prosthesis\n* Use of the device they will be describing for at least six months (with the exception of sensory augmentation)\n\nExclusion Criteria:\n\n* Significant hearing impairment which would prevent telephone communication.\n* Unwillingness or inability to discuss experiences with prostheses\n* Emotional disturbance related to discussion the prosthesis or limb loss",{"count":119,"type":21},178,"OBSERVATIONAL","The goal is to understand the critical factors associated with outcome acceptance following upper limb loss. The investigators aim to develop a unified theoretical model that describes the psychosocial experience of upper limb prosthesis use and predicts outcome acceptance following upper limb loss. The investigators will also examine experiences with prosthesis education, selection, and training as well as how psychological and social issues impact prosthesis use. In addition, the investigators will use the findings to develop a prototype decision tool to assist with matching persons to prostheses. Study findings will help providers, technology developers, and researchers better understand the complex experience of upper limb prosthesis use.\n\nThis conceptual framework will enable clinicians and researchers to evaluate and predict patient outcomes following limb loss, and to design interventions that improve outcomes. The proposed study is a mixed methods (qualitative and quantitative) study using an observational design. The qualitative component of the study will involve data collection through telephone interviews with 42 participants and analyses using a grounded theory approach with constant comparison methods. The quantitative component involves administration of standardized measures quantifying constructs of the theoretical model in 120 participants and analyses to produce a structural equation model of outcome acceptance. Participants will include persons with unilateral acquired upper limb loss at the trans radial or trans humeral level who use currently available prosthetic devices. Up to 16 individuals will participate in a series of focus groups that will be conducted to provide feedback on the model generated from previous data.",[94,91,60,123,27],"Upper Limb Amputation Above Elbow (Injury)",[125,126,127,128,129,33,130,131,132,133,134,135,136],"Upper Limb Prosthesis User","Survey","Interview","User Experience","Body-powered","Multiple degree of freedom","Sensory Feedback","Prosthetic device features","Upper Limb Loss","Amputee","Outcome Acceptance","Qualitative Research","2025-04-01",{"date":139,"type":38},"2025-04-04",{"date":141,"type":38},"2020-12-16",{"date":143,"type":21},"2026-09-30",{"name":145,"class":146},"Louis Stokes VA Medical Center","FED"]