[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"upper-limb-function\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:upper-limb-function":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,39,72,100,128],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100632150","a-functional-near--infrared-spectroscopy-study-on-the-brain-activation-characteristics-of-stroke-patients-during-mirror-movement-100632150",false,"NCT07509944","A Functional Near- Infrared Spectroscopy Study on the Brain Activation Characteristics of Stroke Patients During Mirror Movement","Inclusion Criteria:\n\n* It meets the diagnostic criteria of the \"Guidelines for the Prevention and Treatment of Cerebrovascular Diseases in China\", and is diagnosed as cerebral infarction or cerebral hemorrhage by CT or MRI.\n* The first stroke occurred;\n* The muscle strength of the flexor and extensor muscles of the affected finger is ≤ grade 1.\n* Right-handed player\n* Muscle tone improvement: Asworth level 2 or below;\n* The disease course is within 6 months and the condition is stable.\n* Age: 18 to 75 years old, with normal vision and hearing or corrected to normal.\n\nExclusion Criteria:\n\n* Those with an MMSE score less than 20, severe memory, communication and speech command comprehension disorders, and those who cannot cooperate with examinations and treatments;\n* Those with a history of epilepsy;\n* Those with a history of stroke, traumatic brain injury or brain tumor in the past;\n* Those with peripheral nervous system injuries other than stroke as diagnosed by imaging;\n* Those with visual spatial impairments such as visual field defects and unilateral neglect;\n* Skull defect or metal bone plates\n* For those who are not suitable for functional near-infrared examination;\n* Those with a history of intracranial surgery.\n* Patients with lesion areas in the cerebellum or brainstem.","ALL","18 Years","75 Years",{"count":19,"type":20},25,"ESTIMATED","OBSERVATIONAL","After the selected patients are determined, the researchers of this study need to have full communication with the patients. The location is the rehabilitation ward of our hospital and the time is\n\nBefore joining the group. During this process, the patient should be informed of the purpose, procedures and processes of the trial. The informed consent form should be signed by the patient himself\u002Fherself. Such as the patient\n\nIlliterate, the informed consent process was witnessed by an independent witness and signed. The subject pressed their fingerprint at the signature. In the study process fully\n\nListen to and respond to the questions and opinions of the subjects or their representatives.",[24,25],"Stroke","Upper Limb Function","RECRUITING","2026-03-29",{"date":29,"type":30},"2026-04-03","ACTUAL",{"date":32,"type":30},"2024-05-01",{"date":34,"type":20},"2030-10-01",{"name":36,"class":37},"Second Affiliated Hospital, School of Medicine, Zhejiang University","OTHER",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":4,"eligibilityCriteria":44,"healthyVolunteers":11,"sex":15,"minAge":45,"maxAge":46,"enrollmentInfo":47,"targetDuration":4,"studyType":49,"phases":50,"briefSummary":52,"conditions":53,"keywords":58,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":70,"locationsCount":38},"100587210","effect-of-task-specific-electrical-stimulation-on-upper-limb-gross-motor-skills-in-children-with-spastic-quadriplegia-100587210","NCT06925425","Effect of Task Specific Electrical Stimulation on Upper Limb Gross Motor Skills in Children With Spastic Quadriplegia","Inclusion Criteria:\n\n1. Their age will be ranged from 2 to 6 years. Their grade of spasticity will be from 1+ to 2 according to Modified Ashworth scale (Baunsgaard etal., 2016). (APPENDIX II).\n2. They will be on Level III and IV according to Gross Motor Functional Classification System (GMFCS) (Palisano et al., 2008).(APPENDIX III).\n3. Parents\u002Flegals representatives consenting to their child's participation 5 - Diagnosed with Spastic Quadriplegic cerebral palsy\n\nExclusion Criteria:\n\n1. Previous neurological or orthopedic surgery in the upperextremities.\n2. Fixed deformity in the joints of upper limb. 3- Severe hearing and visual defect.\n\n4-Irregular attendance at assessments or therapy sessions","2 Years","6 Years",{"count":48,"type":20},30,"INTERVENTIONAL",[51],"NA","Cerebral palsy is a non-progressive lesion of the brain occurring before 2 years of age resulting in disorders of posture and movement.( Ostensjo S, 2004)( Keles MN, 2018). Although non- progressive, motor impairments develop as the child grows leading to activity and participation restriction.\n\nFor children with CP, body function and structure impairments include changes in muscle tone and strength that affect the ability to control movement, specifically in regard to postural responses, selective control, regulation of activity, ability to learn unique movements, and inappropriate sequencing.(Ross SA,2007)( Ostensjo S, 2004) .\n\nLack of proper loading and maladaptive muscle pulls over time causes the skeletal system to adapt to positions of malalignment, malformation, and overall bone weakness (Beckung E, 2007) (Elbasan B, 2018).\n\nThese changes lead to delays in the natural progression of gross motor skills. As the child falls behind in motor function, they also fall behind in cognitive stimulation and development.( Akaya KU, 2018) . Understanding the anatomical and physiological implications that CP has on the developing child is necessary for physical therapists to treat this population, especially when utilizing electrical stimulation.\n\nSpastic quadriplegia Is a type of cerebral palsy that affects all four limbs and typically involves significant motor impairment. It results from brain damage that occurs before, during, or shortly after birth, affecting the areas of the brain responsible for movement and coordination.\n\nElectrical stimulation is a mode of physical therapy that can be utilized in the treatment of various nerve and muscle injuries, in addition to patients with acute and chronic pain. It involves an electrical pulse applied to a muscle or nerve that activates excitable tissue utilizing internal or external electrodes to build muscle strength, reduce pain, as well as create or support limb movement (Kerr C, 2007).\n\nTask-specific electrical stimulation (TASES) is a therapeutic technique used primarily in rehabilitation settings to enhance motor function. The primary aim of TASES is to facilitate movement and improve motor learning by applying electrical stimulation to specific muscles during targeted tasks.",[54,55,56,25,57],"Cerebral Palsy (CP)","Spastic Cerebral Palsy","Quadriplegic Cerebral Palsy","Gross Motor Delay",[59,60,61,62,63],"TASES","Cerebral palsy","Gross motor skills","Upper limb","Task specific electrical stimulation","2026-03-27",{"date":66,"type":30},"2026-04-01",{"date":68,"type":30},"2025-05-01",{"date":27,"type":20},{"name":71,"class":37},"Kafrelsheikh University",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":49,"phases":82,"briefSummary":83,"conditions":84,"keywords":85,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":38},"100580806","investigating-the-effects-of-transcranial-stimulation-to-advance-stroke-rehabilitation-100580806","NCT06842095","Investigating the Effects of Transcranial Stimulation to Advance Stroke Rehabilitation","Investigating the Effects of Beta Transcranial Stimulation to Advance Stroke Rehabilitation","T-STAR","Inclusion Criteria:\n\n* Participant is willing and able to give informed consent for participation in the study.\n* Aged 18 years or above.\n* Clinical diagnosis of stroke affecting the upper limb, with sufficient ability to perform the upper limb reaching task.\n* At least 3 months post-stroke and discharged from inpatient care.\n\nExclusion Criteria:\n\n* Inability to follow task instructions.\n* Other neurological condition affecting movement (e.g. Parkinson's Disease, Multiple Sclerosis).\n* Standard contraindications to non-invasive brain stimulation (TMS, tACS). including (but not limited to) the presence of intracranial metallic or magnetic hardware, seizures, pregnancy, and the presence of a pacemaker or other stimulators\u002Fimplants.\n* Insufficient verbal and written English to comprehend the study and provide informed consent.",{"count":81,"type":20},60,[51],"Non-invasive brain stimulation (NIBS) has the potential to boost rehabilitation after stroke by creating a 'pro-plastic' environment, where the brain is more adaptable in response to movement (motor) training. However, responses to classical NIBS protocols are highly variable.\n\nMovement-related changes in specific brain rhythms have previously been shown to be related to recovery of hand\u002Farm function after a stroke. The investigators propose to use NIBS to target movement-related activity in the beta band (13-30Hz) within the motor cortical regions of the brain. The investigators will use a type of NIBS called transcranial alternating current stimulation (tACS), which uses a sinusoidally-varying electrical current where the stimulation frequency is determined to be relevant to the underlying brain rhythms of interest, and the stimulation timed to coincide with specific phases of the hand\u002Farm movement.\n\nThe primary aim is to investigate whether beta-tACS improves upper limb movement in stroke survivors.",[24,25],[86,24,87,88,89,90],"Non-Invasive Brain Stimulation","Upper Limb","Electroencephalography","Transcranial Alternating Current Stimulation","Beta Oscillations","2025-03-04",{"date":93,"type":30},"2025-03-07",{"date":95,"type":30},"2025-02-01",{"date":97,"type":20},"2027-02-28",{"name":99,"class":37},"University of Oxford",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":108,"sex":15,"minAge":16,"maxAge":109,"enrollmentInfo":110,"targetDuration":112,"studyType":21,"phases":4,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":118,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":4},"100580255","upper-limb-functional-index-100580255","NCT06834919","Upper Limb Functional Index","Translation, Cross-Cultural Adaptation, Validity and Reliability of Upper Limb Functional Index in Albanian Population","ULFI-A","Inclusion Criteria:\n\n* shoulder pain\n* arm pain\n* myofascial pain\n* muscular pain\n* trigger points\n* arthritis\n\nExclusion Criteria:\n\n* tumor\n* metabolic disease\n* neurologic conditions",true,"80 Years",{"count":111,"type":20},200,"7 Days","To translate and validate the Upper Limb Functional Index into Albanian for use in the Albanian-speaking population.",[25,115,116,117],"Upper Limb Pain","Upper Limb; Injury, Superficial, Multiple","Upper Limb Rehabilitation","NOT_YET_RECRUITING","2025-02-13",{"date":121,"type":30},"2025-02-19",{"date":123,"type":20},"2025-02-18",{"date":125,"type":20},"2025-03-15",{"name":127,"class":37},"Universidad Católica San Antonio de Murcia",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":132,"acronym":133,"eligibilityCriteria":134,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":135,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":137,"conditions":138,"keywords":140,"overallStatus":118,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":4},"100572977","investigating-the-upper-limb-during-the-first-6-months-after-sustaining-a-cervical-spinal-cord-injury-100572977","NCT06740279","Investigating the Upper Limb During the First 6 Months After Sustaining a Cervical Spinal Cord Injury,","In Ul 6 SCI","Inclusion Criteria:\n\n* Signed informed consent\n* Acute onset Cervical SCI (traumatic and non-traumatic) C0-C7 AIS A-D that affects motor function in the upper limb.\n* Over the age of 18 at admission\n* Admitted for rehabilitation at one of the study sites.\n\nExclusion Criteria:\n\n* For the surveys: Inability to understand Swedish or English in writing.",{"count":136,"type":20},210,"The goal of this observational study is to investigate and describe the injury patterns, secondary complications, and biomechanical properties of the upper limb during the initial 6 months post-SCI.\n\nThe overarching objective is to investigate and describe the trajectory of upper limb functioning, secondary complications, and biomechanical properties of the upper limb during the initial 6 months post-SCI and explore factors influencing functional use of the hands at 6 months after injury.",[139,25],"Spinal Cord Injuries (SCI)",[141,62,142,143,144,145,146],"Spinal cord injury","tetraplegia","Quadriplegia","hand function","Activities of daily living","grip ability","2024-12-13",{"date":149,"type":30},"2024-12-18",{"date":151,"type":20},"2025-01-07",{"date":153,"type":20},"2026-12-30",{"name":155,"class":156},"Vastra Gotaland Region","OTHER_GOV"]