[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"uremic-osteodystrophy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:uremic-osteodystrophy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100534054","multi-center-clinical-study-on-hemoperfusion-of-kha80-100534054",false,"NCT06233838","Multi-center Clinical Study on Hemoperfusion of KHA80","Prospective, Multicenter, Randomized, Open Label Study on the Efficacy and Safety of Comparison of KHA80 Blood Perfusion Combined With Hemodialysis and Conventional Hemodialysis in Clearing IL-6, β2-MG and PTH in Maintenance Hemodialysis Patients","Inclusion Criteria:\n\n1. Age ≥18 years old, regardless of sex;\n2. According to the 2012 KDIGO guidelines, it was diagnosed as CKD5 (EGFR ≦ 15ml\u002F(min ˙ 1.73m2));\n3. receive regular hemodialysis (including hemodialysis filtration) for 4 hours twice a week for ≧3 months;\n4. blood β 2-mg ≥ 30 mg\u002FL and\u002For PTH ≥ 600 pg\u002FmL and\u002For IL-6 ≥ 16.2 pg\u002FmL;\n5. Sign the informed consent form.\n\nExclusion Criteria:\n\n1. Those who are known to have allergic reactions, contraindications or intolerance to the materials of dialyzers and hemoperfutors;\n2. Patients with severe bleeding tendency and active bleeding, or with definite coagulation dysfunction, with a platelet count of \\\u003C 60× 109\u002FL;\n3. Hemodialysis blood flow \\\u003C 200 ml\u002Fmin.\n4. Kt\u002FV\\\u003C1.2；\n5. Serum albumin \\\u003C 30g\u002FL;\n6. Parathyroid resection within one year;\n7. people with low blood pressure and severe cardiopulmonary insufficiency;\n8. lactating or pregnant women or those who plan to be pregnant within one year;\n9. infection, history of malignant tumor, active stage of rheumatic immune disease;\n10. Patients whose life expectancy is less than one year;\n11. Other clinical researchers are currently or recently (within 30 days);\n12. According to the researcher's judgment, the patient has other unsuitable conditions.","ALL","18 Years",{"count":19,"type":20},394,"ESTIMATED","INTERVENTIONAL",[23],"NA","To evaluate the decreasing rate of blood IL-6, β2-MG and PTH in maintenance hemodialysis patients in the 52nd week compared with routine hemodialysis.",[26,27,28],"Uremia","Uremic Osteodystrophy","Dialysis Related Complication",[30,31,32,33,34],"KHA80","Maintenance hemodialysis","IL-6","β2-MG","PTH","RECRUITING","2025-01-10",{"date":38,"type":39},"2025-01-14","ACTUAL",{"date":41,"type":20},"2025-01-13",{"date":43,"type":20},"2027-05-31",{"name":45,"class":46},"First Affiliated Hospital of Fujian Medical University","OTHER"]