[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ureteral-stone\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ureteral-stone":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,40,68],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100638322","patient-positioning-for-treatment-of-proximal-ureteral-stones-100638322",false,"NCT07601932","Patient Positioning for Treatment of Proximal Ureteral Stones","Optimal Patient Positioning and Strategy for the Treatment of Proximal Ureteral Stones","Inclusion criteria:\n\n* Adults aged 18 years and older.\n* Diagnosed with kidney stones and scheduled for fURS.\n* Stone burden \\> 1 cm and\u002For multiple stones will be eligible.\n* Able and willing to provide informed consent.\n\nExclusion criteria:\n\n* Pregnant persons as determined by pre-operative urine pregnancy test (standard of care at the institution)\n* Untreated UTI\n* Patients with urinary anomalies (e.g., urinary diversion, ureteral reconstruction, horseshoe kidney)\n* Single stone \\\u003C 1 cm","ALL","18 Years",{"count":19,"type":20},54,"ESTIMATED","INTERVENTIONAL",[23],"NA","Ureteroscopic management of proximal ureteral stones presents technical challenges including stone retropulsion, prolonged operative time, and conversion to intrarenal treatment. Reverse Trendelenburg positioning has been shown to reduce proximal stone migration and operative time in ureteral stones, while the T-tilt position improves intrarenal stone clearance. The optimal strategy for proximal ureteral stones (treating stones in situ using reverse Trendelenburg versus pushing stones into the kidney followed by intrarenal treatment in T-tilt) remains unknown.\n\nThis randomized controlled trial compares these two strategies, with primary focus on operative time as a measure of procedural efficiency.\n\nA total of 54 patients (27 per arm) will be enrolled at Mount Sinai West.",[26],"Ureteral Stone","RECRUITING","2026-06-02",{"date":30,"type":31},"2026-06-04","ACTUAL",{"date":33,"type":31},"2026-05-21",{"date":35,"type":20},"2027-12",{"name":37,"class":38},"Icahn School of Medicine at Mount Sinai","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":21,"phases":50,"briefSummary":51,"conditions":52,"keywords":54,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":39},"100615849","access-sheath-and-stent-trial-100615849","NCT07297953","Access Sheath and Stent Trial","Access Sheath and stENT Trial","ACCENT","Inclusion Criteria:\n\n* Provision of signed and dated informed consent form\n* Stated willingness to comply with all study procedures and availability for the duration of the study\n* Planned ureteroscopy using a Ureteral Access Sheath (UAS) for treatment of unilateral kidney and\u002For ureteral stones in patients that have an existing ureteral stent (pre-stented)\n* Planned treatment of unilateral renal and\u002For ureteral stones, in a single procedure.\n* Renal stone defined as only renal location of stone(s)\n* Ureteral stone defined as ureteral only location of stone(s)\n* Ureteral and renal stone(s)\n* No evidence of significant ureteral injury on intra-operative assessment (Post-Ureteroscopy Lesion Scale (PULS) Grade 0 or 1)\n* Ability and willingness to complete and adhere to survey questions and responses throughout study duration.\n\nExclusion Criteria:\n\n* Pregnancy\n* Ureteric injury during ureteroscopy (PULS ≥ Grade 2)\n* Evidence of ureteral stricture\n* Anatomical abnormalities (e.g., solitary, horseshoe, fused crossed ectopia, pelvic kidney, urinary diversion)\n* Known planned secondary or staged procedure\n* Indwelling nephrostomy tube\n* Bilateral ureteroscopy",{"count":49,"type":20},184,[23],"The study is being completed to compare patient reported outcomes for stent omission vs. placement after using a ureteral access sheath for uncomplicated ureteroscopy.\n\nParticipants that consent for the study will complete baseline PRO questionnaires. A UAS will be used during surgery, and the size left to the discretion of the surgeon. At the end of the procedure, the urologist will evaluate the ureter for iatrogenic injury, and the ureter will be graded using the Post Ureteroscopic Lesion Scale (PULS). Patients assessed with PULS 0 and PULS 1 will meet 2nd stage eligibility and will be randomized 1:1 to either stent omission or stent placement. When a stent is placed, the stent type and decision to leave a string (tether) will be at the operating urologist's discretion.\n\nHypothesis:\n\n\\- stent omission arm will be non-inferior to stent placement in Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Interference and Pain Intensity, and have lower 30-day healthcare utilization.",[53,26],"Kidney Stone",[55,56,57,58],"Ureteral stent","Ureteroscopy and lithotripsy","Surveys","Quality of life","2025-12-08",{"date":61,"type":31},"2025-12-22",{"date":63,"type":31},"2025-09-24",{"date":65,"type":20},"2026-10",{"name":67,"class":38},"University of Michigan",{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":77,"targetDuration":4,"studyType":21,"phases":79,"briefSummary":80,"conditions":81,"keywords":82,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":39},"100494200","upurs-trial-for-patient-centered-management-of-symptomatic-obstructing-stones-100494200","NCT05715086","UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones","Upfront vs Postponed Ureteroscopy (UPURS) Trial for Patient-centered Management of Symptomatic Obstructing Stones","UPURS","Inclusion Criteria:\n\n* Presenting to the Emergency Department (ED)\n* Adult (\\> 18 yo)\n* ≥5mm ureteral stone diagnosed on CT scan\n* Presence of symptoms (pain, nausea, vomiting, hematuria)\n\nExclusion Criteria:\n\n* Strict indication for stent\n* Stone burden not amenable to Ureteroscopy (URS)\n* Dirty urine analysis (UA) or positive urine culture (UCx)\n* Transplant kidney\n* Presence of conduit\n* Comorbidities not optimized for surgery\n* Strong preference for surgery or observation",true,{"count":78,"type":20},100,[23],"A prospective, non-blinded, randomized controlled trial studying the management of symptomatic ureteral stones. This study will compare upfront ureteroscopy vs observation and delayed intervention for patients presenting to the emergency department with a symptomatic ureteral stone.",[26],[83],"Symptomatic ureteral stones","2025-01-15",{"date":86,"type":31},"2025-01-17",{"date":88,"type":31},"2023-08-23",{"date":90,"type":20},"2026-06-30",{"name":92,"class":38},"University of California, San Francisco"]