[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ureteric-stone\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ureteric-stone":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,65],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100636176","safety-and-efficacy-of-combination-of-tamsulosin-04-mg-plus-tadalafil-5mg-versus-25-mg-100636176",false,"NCT07562282","Safety and Efficacy of Combination of Tamsulosin 0.4 mg Plus Tadalafil 5mg Versus 2.5 mg","Safety and Efficacy of Combination of Tamsulosin 0.4 mg Plus Tadalafil 5mg Versus 2.5 mg for Ureteric Stent Related Symptoms","Inclusion Criteria:\n\n\\- patients older than 18 years of age, with presence of a double-J (DJ) stent (polyurethane) post endoscopic stone removal.\n\nExclusion Criteria:\n\n* Patients younger than 18 years of age were excluded.\n* Patients with a history of prostate or bladder surgery were excluded.\n* Patients with prior lower urinary tract procedures were excluded.\n* Patients with cancer were excluded.\n* Patients with neurological conditions were excluded.\n* Patients with a history of pelvic radiation were excluded.\n* Patients with diabetes were excluded.\n* Patients with kidney dysfunction (acute or chronic) were excluded.\n* Patients with a solitary kidney were excluded.\n* Patients with congenital urinary anomalies were excluded.\n* Patients taking the following medications were excluded:\n\n  * α-blockers\n  * beta-blockers\n  * calcium channel blockers\n  * 5-alpha reductase inhibitors\n  * PDE5 inhibitors\n  * anticholinergics\n  * nitrates\n* Patients with cardiac issues were excluded.\n* Patients with residual stone fragments after surgery were excluded.\n* Patients with multiple or bilateral ureteral stones were excluded.\n* Patients with long-term or bilateral stents requiring frequent changes were excluded.\n* Patients with interstitial cystitis were excluded.\n* Patients with chronic cystitis were excluded.\n* Patients with prostatitis were excluded.\n* Pregnant women were excluded.\n* Breastfeeding women were excluded.\n* Patients unavailable for follow-up were excluded.","ALL","18 Years","71 Years",{"count":20,"type":21},140,"ESTIMATED","INTERVENTIONAL",[24],"NA","Ureteral stenting is a common urological procedure performed to relieve obstruction and facilitate urinary drainage. Despite its effectiveness, stent-related symptoms (SRS) such as dysuria, frequency, urgency, flank pain, and sexual discomfort negatively affect patient quality of life.\n\nPharmacological management with alpha-blockers such as Tamsulosin and phosphodiesterase-5 inhibitors (PDE5i) such as Tadalafil has shown promise in reducing SRS. While low-dose Tadalafil (2.5 mg) has not been explored, its comparative effectiveness against the standard 5 mg dose when combined with Tamsulosin remains under-researched. This study aims to evaluate the difference in reduction of SRS between Tamsulosin with Tadalafil in standard and half dosage.",[27,28],"Kidney Stone","Ureteric Stone","RECRUITING","2026-04-25",{"date":32,"type":33},"2026-05-01","ACTUAL",{"date":35,"type":33},"2025-12-01",{"date":37,"type":21},"2026-07-10",{"name":39,"class":40},"Ain Shams University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":41},"100611979","flexible-vs-semi-rigid-urs-100611979","NCT07247617","Flexible vs Semi-rigid URS","Semi-rigid Ureteroscopy Versus Flexible Ureteroscopy in Upper Third Ureteric Stones Management: a Prospective Randomized Trial","Inclusion Criteria:\n\n* Patients ≥18 years\n* upper ureteric stone\n* ≤20 mm\n\nExclusion Criteria:\n\n* Associated renal stones\n* Any contraindications to Anesthesia",{"count":50,"type":21},100,[24],"To compare the efficacy, safety, success rate, operative time, and cost-effectiveness of flexible ureteroscopy versus semirigid ureteroscopy in the management of upper ureteric stones smaller than 2 cm.\n\nThe investigators' main concern in this study is Upper third ureteric stones to determine which cases can be treated with Semi-Rigid Ureteroscopy, and which one needs flexible ureteroscopy. This depends on several factors:\n\n1. Division of the upper third of the ureter\n2. Stone size\n3. Stone impaction\n4. Surgeon experience\n5. Anesthesia\n6. Ureteric dilatation above the stone\n7. Mini endoscopy",[28,54,55],"Flexible Ureteroscopy","Upper Urinary Tract Stones","2025-11-22",{"date":58,"type":33},"2025-11-25",{"date":60,"type":33},"2025-10-01",{"date":62,"type":21},"2027-01-01",{"name":64,"class":40},"Assiut University",{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":4,"eligibilityCriteria":70,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":71,"targetDuration":4,"studyType":22,"phases":73,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":41},"100572105","efficacy-of-intra-ureteric-aminophylline-installation-after-failed-stone-accessibility-by-semi-rigid-ureteroscopy-prospective-trial-100572105","NCT06728943","Efficacy of Intra-Ureteric Aminophylline Installation After Failed Stone Accessibility by Semi-rigid Ureteroscopy. Prospective Trial","Inclusion Criteria:\n\n* The study will include patients with failed stone accessibility by semi-rigid ureteroscopy.\n\nExclusion Criteria:\n\n* Child age group\n* Pre stented patients\n* Contraindications to aminophylline (hypersensitivity to drug components, pregnancy or lactation ,…)\n* Contraindications to ureteroscopy (active urinary tract infection - Contraindications to general or spinal anesthesia - Uncorrected bleeding disorders)",{"count":72,"type":21},300,[24],"In this study we will test the effect of local intraureteric aminophylline instillation through Ureteric stent and Reaching stone without the need of ballon dilataion",[76,77,28],"Ureterocopic Lithotripsy","Stone Ureter",[79,80,81,82],"ureteroscopy","stone ureter","ureteral dilatation","failed ureteroscopy","2024-12-08",{"date":85,"type":33},"2024-12-11",{"date":87,"type":33},"2024-12-01",{"date":89,"type":21},"2028-12-01",{"name":91,"class":40},"Al-Azhar University"]